Pan paniscus (bonobo): 100974638
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Entry
100974638 CDS
T02283
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase 3 isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
pps
Pan paniscus (bonobo)
Pathway
pps00220
Arginine biosynthesis
pps00330
Arginine and proline metabolism
pps01100
Metabolic pathways
pps04020
Calcium signaling pathway
pps04022
cGMP-PKG signaling pathway
pps04066
HIF-1 signaling pathway
pps04071
Sphingolipid signaling pathway
pps04151
PI3K-Akt signaling pathway
pps04370
VEGF signaling pathway
pps04371
Apelin signaling pathway
pps04611
Platelet activation
pps04915
Estrogen signaling pathway
pps04921
Oxytocin signaling pathway
pps04926
Relaxin signaling pathway
pps04931
Insulin resistance
pps04933
AGE-RAGE signaling pathway in diabetic complications
pps05415
Diabetic cardiomyopathy
pps05417
Lipid and atherosclerosis
pps05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pps00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
100974638 (NOS3)
00330 Arginine and proline metabolism
100974638 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
100974638 (NOS3)
04371 Apelin signaling pathway
100974638 (NOS3)
04066 HIF-1 signaling pathway
100974638 (NOS3)
04020 Calcium signaling pathway
100974638 (NOS3)
04071 Sphingolipid signaling pathway
100974638 (NOS3)
04022 cGMP-PKG signaling pathway
100974638 (NOS3)
04151 PI3K-Akt signaling pathway
100974638 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100974638 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
100974638 (NOS3)
04921 Oxytocin signaling pathway
100974638 (NOS3)
04926 Relaxin signaling pathway
100974638 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100974638 (NOS3)
05418 Fluid shear stress and atherosclerosis
100974638 (NOS3)
05415 Diabetic cardiomyopathy
100974638 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100974638 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
100974638 (NOS3)
Enzymes [BR:
pps01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
100974638 (NOS3)
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Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
100974638
NCBI-ProteinID:
XP_008966187
Ensembl:
ENSPPAG00000039019
LinkDB
All DBs
Position
6:187411083..187436160
Genome browser
AA seq
1306 aa
AA seq
DB search
MPQPPRCSPRALLDTWAPTYQPQSSQRNPGVRPPTLQASGRGAEALEPPSRACSCPIVYG
TGAGRGPALESPLPLPPPLGPLPLPKEKARALLEQAAEWTHSNMGNLKSVAQESGPPCGL
GLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLTQPPEGPKFPRVKNWEVG
SITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPEQLLSQARDFINQYYSS
IKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFD
ARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDFRIWNSQLVRYAGYRQQ
DGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPPELFLLPPELVLEVPLEH
PTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTEIGTRNLCDPHRYNILE
DVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHHAATASFMKHLENEQKA
RGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWKGSAAKGTGITRKKTFK
EVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRLFRKAFDPRVLCMDEYD
VVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSPRPEQHKSYKIRFNSIS
CSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCAFARAVDTRLEELGGE
RLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAARDIFSPKRSWKRQRYRL
SAQAEGLQLLPGLIHVHRRKMFQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGD
HIGVCPPNRPGLVEALLSRVEDPPAPTEPVAVEQLEKGSPGGPPPGWVRDPRLPPCTLRQ
ALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPRRYEEWKWFRCPTLLEVLEQ
FPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVLAYRTQDGLGPLHYGVCS
TWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFRGFWQERLHDIESKGL
QPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSREPDNPKTYVQDILRTELA
AEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDMELDEAGDVIGVLRDQQRYHE
DIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDPPGSDTNSP
NT seq
3921 nt
NT seq
+upstream
nt +downstream
nt
atgccccagcccccacgctgcagccccagggctctgctggacacctgggctcccacttat
cagcctcagtcctcacagcggaacccaggcgtccggccccccacccttcaggccagcggg
cgtggagctgaggctttagagcctcccagccgggcttgttcctgtcccattgtgtatggg
acaggggcggggcgagggccagcactggagagccccctcccactgccccctcctctcggt
cccctccctcttcctaaggaaaaggccagggctctgctggagcaggcagcagagtggacg
cacagtaacatgggcaacttgaagagcgtggcccaggagtctgggccaccctgcggcctg
gggctggggctgggccttgggctgtgcggcaagcagggcccagccaccccggcccctgag
cccagccgggccccagcatccctactcccgccagcgccagaacacagccccccgagctcc
ccgctaacccagcccccagaggggcccaagttccctcgtgtgaagaactgggaggtgggg
agcatcacctatgacaccctcagcgcccaggcgcagcaggatgggccctgcaccccaaga
cgctgcctgggctccctggtatttccacggaaactacagggccggccctcccccggcccc
ccggcccctgagcagctgctgagtcaggcccgggacttcatcaaccagtactacagctcc
attaagaggagcggctcccaggcccacgaacagcggcttcaagaggtggaagccgaggtg
gcagccacaggcacctaccagcttagggagagcgagctggtgttcggggccaagcaggcc
tggcgcaacgctccccgctgcgtgggccggatccagtgggggaagctgcaggtgttcgat
gcccgggactgcaggtctgcacaggaaatgttcacctacatctgcaaccacatcaagtat
gccaccaaccggggcaaccttcgctcggccatcacagtgttcccgcagcgctgccctggc
cgaggagacttccgaatctggaacagccagctggtgcgctacgcgggctaccggcagcag
gacggctctgtgcggggggacccagccaacgtggagatcaccgagctctgcattcagcac
ggctggaccccaggaaacggtcgcttcgacgtgctgcccctgctgctgcaggccccagat
gagcccccagaactcttccttctgccccccgagctggtccttgaagtgcccctggagcac
cccacgctggagtggtttgcagccctgggcctgcgctggtacgccctcccagcagtgtcc
aacatgctgctggaaattgggggcctggagttccccgcagcccccttcagtggctggtac
atgagcactgagatcggcacgaggaacctgtgtgaccctcaccgctacaacatcctggag
gatgtggctgtctgcatggacctggatacccggacaacctcgtccctgtggaaagacaag
gcagcagtggaaatcaacgtggccgtgctgcacagttaccagctggccaaagtcaccatc
gtggaccaccacgccgccacggcctctttcatgaagcacctggagaatgagcagaaggcc
agggggggctgccctgcagactgggcctggatcgtgccccccatctcgggcagcctcact
cctgttttccatcaggagatggtcaactatttcctgtccccggccttccgctaccagcca
gacccctggaaggggagtgccgccaagggcaccggcatcaccaggaagaagacctttaaa
gaagtggccaacgccgtgaagatctccgcctcgctcatgggcacggtgatggcgaagcga
gtgaaggcgacaatcttgtatggctccgagaccggccgggcccagagctacgcacagcag
ctggggagactcttccggaaggcttttgatccccgggtcctgtgtatggatgagtatgac
gtggtgtccctcgaacacgagacgctggtgctggtggtaaccagcacatttgggaatggg
gatcccccggagaatggagagagctttgcagctgccctgatggagatgtccggcccctac
aacagctcccctcggccggaacagcacaagagttataagatccgcttcaacagcatctcc
tgctcagacccactggtgtcctcttggcggcggaagaggaaggagtccagtaacacagac
agtgcaggggccctgggcaccctcaggttctgtgtgttcgggctcggctcccgggcatac
ccccacttctgcgcctttgctcgtgcggtggacacacggctggaggaactgggcggggag
cggctgctgcagctgggccagggcgacgagctgtgcggccaggaggaggccttccgaggc
tgggcccaggctgccttccaggccgcctgtgagaccttctgtgtgggagaggatgccaag
gccgccgcccgagacatcttcagccccaaacggagctggaagcgccagaggtaccggctg
agcgcccaggccgagggcctgcagttgctgccaggtctgatccacgtgcacaggcggaag
atgttccaggctacaatccgctcagtggaaaacctgcaaagcagcaagtccacgagggcc
accatcctggtgcgcctggacaccggaggccaggaggggctgcagtaccagccgggggac
cacataggtgtctgcccgcccaaccggcccggccttgtggaggcgctgctgagccgcgtg
gaggacccgccggcgcccactgagcccgtggcagtagagcagctggagaagggcagccct
ggtggccctccccccggctgggtgcgggacccccggctgcccccgtgcacgctgcgccag
gctctcaccttcttcctggacatcacctccccacccagccctcagctcttgcggctgctc
agcaccttggcagaagagcccagggaacagcaggagctggaggccctcagccaggatccc
cgacgctacgaggagtggaagtggttccgctgccccacgctgctggaggtgctggagcag
ttcccgtcggtggcgctgcctgccccactgctcctcacccagctgcctctgctccagccc
cggtactactcagtcagctcggcacccagcacccacccaggagagatccacctcactgta
gctgtgctggcatacaggactcaggatgggctgggccccctgcactatggagtctgctcc
acgtggctaagccagctcaagcccggagaccctgtgccctgcttcatccggggggctccc
tccttccggctgccacccgatcccagcttgccctgcatcctagtgggcccaggcactggc
attgcccccttccggggattctggcaggagcggctgcatgacattgagagcaaagggctg
cagcccactcccatgactttggtgttcggctgccgatgctcccaacttgaccatctctac
cgcgacgaggtgcagaacgcccagcagcgcggggtgtttggccgagtcctcaccgccttc
tcccgggaacctgacaaccccaagacctacgtgcaggacatcctgaggacggagctggct
gcggaggtgcaccgcgtgctgtgcctcgagcggggccacatgtttgtctgcggcgatgtc
accatggcaaccaacgtcctgcagaccgtgcagcgcatcctggcgacggagggcgacatg
gagctggacgaggccggcgacgtcatcggcgtgctgcgggatcagcaacgctaccacgaa
gacattttcgggctcacgctgcgcacccaggaggtgacaagccgcatacgcacccagagc
ttttccttgcaggagcgtcagttgcggggcgcagtgccctgggcgttcgaccctcccggc
tcagacaccaacagcccctga
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