Pan paniscus (bonobo): 100975452
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Entry
100975452 CDS
T02283
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
pps
Pan paniscus (bonobo)
Pathway
pps00230
Purine metabolism
pps01100
Metabolic pathways
pps04024
cAMP signaling pathway
pps05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pps00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100975452 (PDE10A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
100975452 (PDE10A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100975452 (PDE10A)
Enzymes [BR:
pps01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
100975452 (PDE10A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
100975452 (PDE10A)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
HD
SpoVT_C
PEX15_N
DUF7334
Motif
Other DBs
NCBI-GeneID:
100975452
NCBI-ProteinID:
XP_003820278
Ensembl:
ENSPPAG00000034143
UniProt:
A0A2R9AYB4
LinkDB
All DBs
Position
5:complement(185514841..186181000)
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AA seq
1057 aa
AA seq
DB search
MASLEEPLAPRPQGPLPAAGDEPGCGPGKLRPEPRLSAAGGGSAAGPGPAPEWPGRGRAE
RAAPPRPPPSSAGRPSPAGGPGALSARGGGCGWVAARAPLALAFSSRVPSSSPSFFYFWP
PPPPPPPSFLPSSSAFHLPVRLPGREGAAAAAAAAAGGGGDAGGGGGGGQEAAPLSVPTS
SSHRGGGGSGGGRRRLFLSPALQGLLLPARAGPRPPPPPRLPLGQAARRAGSPGFPGAGP
GGGGQTPRRPQGASFALAAAAALLFGSDMEDGPSNNASCFRRLTECFLSPSLTDEKVKAY
LSLHPQVLDEFVSESVSAETVEKWLKRKNNKSEDESAPKEVSRYQDTNMQGVVYELNSYI
EQRLDTGGDNQLLLYELSSIIKIATKADGFALYFLGECNNSLCIFTPPGIKEGKPRLIPA
GPITQGTTVSAYVAKSRKTLLVEDILGDERFPGGTGLESGTRIQSVLCLPIVTAIGDLIG
ILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFD
NIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPVFKKTKEI
RFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVV
QMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICT
SEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFI
MSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSN
SYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIA
TDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDI
YAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLL
KACRDNLSQWEKVIRGEETATWISSPSVAQKAAASED
NT seq
3174 nt
NT seq
+upstream
nt +downstream
nt
atggccagcctcgaggagcctcttgctccccgcccccagggtcccctgccagcggccggg
gacgagccgggctgcggccccggcaaactccgcccggaaccccggctcagcgcggccggc
ggggggagcgcggcgggcccgggcccggcccccgagtggcctggccgtggccgggcggag
cgcgccgcgcccccgcgcccgcccccctcctccgcaggccgccccagccccgctgggggc
cccggcgccctctctgcgcgcggcggcggctgcggctgggtcgcggcccgcgctcccttg
gcgctcgccttctcctcccgggtcccctcctcctctccatctttcttttacttctggccg
ccgccccccccgccccctccctcttttctcccctcctcatctgcctttcacctccccgtg
cgtctcccaggaagggagggcgcggcggcggcggcggcggcggcggcgggaggaggcggc
gatgctggcggaggaggaggaggaggacaagaggcagctcccttgagcgtccccaccagc
agtagtcaccgcggcggcggtggcagcggcggcgggcggcggcggctcttcctctcgcct
gcgctccagggcttgctgcttccagcccgtgccggtccccggccgccgccgccgccccgg
ctcccccttggccaggccgcccgccgcgcgggctcccccggcttccccggcgccggccca
ggcggcggcggccaaactccgcggcgtccccagggcgccagcttcgccctcgccgccgcg
gccgcgctcctcttcggctccgacatggaagatggaccttctaataatgcgagctgcttc
cgaaggctgaccgagtgcttcctgagccccagtttgacagatgaaaaagtgaaggcatat
ctttctcttcacccccaggtattagatgaatttgtatctgaaagtgttagtgcagagaca
gtagagaaatggctgaagaggaagaacaacaaatcagaagatgaatcggctcctaaggaa
gtcagcaggtaccaagatacgaatatgcagggagttgtatatgaactaaacagctatata
gaacaacggttggacacaggaggagacaaccagctactcctctatgaactgagcagcatc
attaaaatagccacaaaagccgatggatttgcactgtatttccttggagagtgcaataat
agcctgtgcatattcacaccacctgggataaaggaaggaaaaccccgcctcatccctgct
gggcccatcactcagggcaccaccgtctctgcttatgtggccaagtccaggaaaacactg
ctagtagaagacatccttggagatgaacgatttccaggaggtactggactggaatcaggg
actcgtatccagtctgttctttgcttaccaattgtcactgcaattggtgacttgattggt
attctcgagctgtatcggcactggggcaaagaagccttctgtcttagtcaccaggaggtt
gcaacagcaaatcttgcctgggcttcagtagcaatacatcaggtgcaggtatgcagaggc
cttgccaaacagacagaattgaatgacttcctactcgacgtatcaaaaacatattttgat
aacatagttgcaatagattctctacttgaacacataatgatatatgcaaaaaacctggtg
aatgccgatcgttgtgcacttttccaggtagaccataagaacaaggagttatattcagac
ctttttgatattggagaggaaaaggaaggaaaacctgtcttcaagaagaccaaagagata
agattttcaattgagaaaggaattgctggccaagtagcaagaacaggggaagtcctgaac
attccagatgcctatgcagacccacgctttaacagagaagtagacttgtacacaggctac
accacgcggaacatcctgtgcatgcccatcgtcagccgaggcagcgtgataggtgtggtg
cagatggtcaacaaaatcagtggcagtgccttctctaaaacagatgaaaacaacttcaaa
atgtttgccgtcttttgtgctttagccttacactgtgctaatatgtatcatagaattcgc
cactcagagtgcatttaccgggtaacgatggaaaagctgtcctaccatagcatttgtact
tcggaagagtggcaaggcctcatgcaattcacccttcccgtgcgtctctgcaaagaaatt
gaattattccactttgacattggtccttttgaaaacatgtggcctggaatttttgtctac
atggttcatcggtcctgtgggacatcctgctttgagcttgaaaagttgtgtcgttttatt
atgtctgtgaagaagaactatcggcgggttccttatcacaactggaagcatgcggtcact
gtagcacactgcatgtatgccatacttcagaacaatcacacgcttttcacagaccttgag
cgcaaaggactgctgattgcgtgtctgtgtcatgacctggaccacaggggcttcagtaac
agctacctgcagaagttcgaccaccctctggccgctctctactccacttccaccatggag
cagcaccacttctcccagaccgtgtccatcctccagttggaagggcataatatcttctct
actctgagctccagtgaatatgagcaggtgcttgagatcatccgcaaagccatcattgcc
acagaccttgctttatactttggaaacaggaagcagttggaagagatgtaccagaccgga
tcactaaaccttaataatcaatcacatagagaccgtgtaattggtttgatgatgactgcc
tgtgacctttgttctgtgacaaaactgtggcccgttacaaaattgacggcaaatgatata
tatgcagaattctgggctgagggtgatgaaatgaagaaattgggaatacagcctattcct
atgatggacagagacaagaaggatgaagtcccccaaggccagcttgggttctacaatgcc
gtggccattccctgctatacaacccttacccagatcctccctcccacggagcctcttctg
aaagcatgcagggataatctcagtcagtgggagaaggtgattcgaggggaggagactgca
acctggatttcatccccatccgtggctcagaaggcagctgcatctgaagattga
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integrated database retrieval system
