KEGG   Pan paniscus (bonobo): 100976987
Entry
100976987         CDS       T02283                                 
Symbol
PPP3CA
Name
(RefSeq) protein phosphatase 3 catalytic subunit alpha isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04020  Calcium signaling pathway
pps04022  cGMP-PKG signaling pathway
pps04114  Oocyte meiosis
pps04218  Cellular senescence
pps04310  Wnt signaling pathway
pps04360  Axon guidance
pps04370  VEGF signaling pathway
pps04380  Osteoclast differentiation
pps04625  C-type lectin receptor signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps04658  Th1 and Th2 cell differentiation
pps04659  Th17 cell differentiation
pps04660  T cell receptor signaling pathway
pps04662  B cell receptor signaling pathway
pps04720  Long-term potentiation
pps04724  Glutamatergic synapse
pps04728  Dopaminergic synapse
pps04921  Oxytocin signaling pathway
pps04922  Glucagon signaling pathway
pps04924  Renin secretion
pps05010  Alzheimer disease
pps05014  Amyotrophic lateral sclerosis
pps05020  Prion disease
pps05022  Pathways of neurodegeneration - multiple diseases
pps05031  Amphetamine addiction
pps05152  Tuberculosis
pps05163  Human cytomegalovirus infection
pps05166  Human T-cell leukemia virus 1 infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05170  Human immunodeficiency virus 1 infection
pps05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100976987 (PPP3CA)
   04310 Wnt signaling pathway
    100976987 (PPP3CA)
   04370 VEGF signaling pathway
    100976987 (PPP3CA)
   04020 Calcium signaling pathway
    100976987 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    100976987 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100976987 (PPP3CA)
   04218 Cellular senescence
    100976987 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100976987 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    100976987 (PPP3CA)
   04660 T cell receptor signaling pathway
    100976987 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    100976987 (PPP3CA)
   04659 Th17 cell differentiation
    100976987 (PPP3CA)
   04662 B cell receptor signaling pathway
    100976987 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    100976987 (PPP3CA)
   04921 Oxytocin signaling pathway
    100976987 (PPP3CA)
   04924 Renin secretion
    100976987 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    100976987 (PPP3CA)
   04728 Dopaminergic synapse
    100976987 (PPP3CA)
   04720 Long-term potentiation
    100976987 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    100976987 (PPP3CA)
   04380 Osteoclast differentiation
    100976987 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100976987 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100976987 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    100976987 (PPP3CA)
   05163 Human cytomegalovirus infection
    100976987 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100976987 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100976987 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100976987 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    100976987 (PPP3CA)
   05020 Prion disease
    100976987 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    100976987 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    100976987 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100976987 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pps01009]
    100976987 (PPP3CA)
Enzymes [BR:pps01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     100976987 (PPP3CA)
Protein phosphatases and associated proteins [BR:pps01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     100976987 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 100976987
NCBI-ProteinID: XP_003829994
Ensembl: ENSPPAG00000042533
UniProt: A0A2R9CDE3
LinkDB
Position
3:complement(99106368..99429647)
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcaattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gttccatttcctccaagtcaccggcttacagcaaaagaagtgtttgataatgatggaaaa
cctcgtgtggatatcttaaaggcgcatcttatgaaggagggaaggctggaagagagtgtt
gcattgagaataataacagagggtgcatcaattcttcgacaggaaaaaaatttgctggat
attgatgcgccagtcactgtttgtggggacattcatggacaattctttgatttgatgaag
ctctttgaagtcgggggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtattgaatgtgtgctgtatttgtgggccttgaaaattctctac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaataaagtattcagaacgcgtatatgatgcctgtatggat
gcctttgactgccttcccctggctgccctgatgaaccaacagttcctgtgtgtacatggt
ggtttgtctccagagattaacactttagatgatatcagaaaattagaccgattcaaagaa
ccacctgcatatggacctatgtgtgatatcctgtggtcagaccccctggaagattttgga
aatgagaagactcaggaacatttcactcacaacacagtcagggggtgttcatacttctac
agttacccggctgtatgtgaattcttacagcacaataacttgttatctatactccgagcc
cacgaagcccaagatgcagggtaccgcatgtacaggaaaagccaaacaacaggcttccct
tctctaattacaattttttcagcaccaaattacttagatgtatacaataacaaagctgca
gtattgaagtatgagaacaatgttatgaatatcaggcaattcaactgttctcctcatcca
tactggcttccaaatttcatggatgtttttacttggtcccttccatttgttggggaaaaa
gtgactgagatgctggtaaatgtcctcaacatctgctcagatgatgaactagggtcagaa
gaagatggatttgatggtgcaacagctgcagcccggaaagaggtgataaggaacaagatc
cgagcaataggcaaaatggccagagtgttctcagtgctcagagaagagagtgagagtgtg
ctgacgctgaaaggcttgaccccaactggcatgctccccagcggagtactttctggaggg
aagcaaaccctgcaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacaacataagatcactagcttcgaggaagccaagggcttagaccgaattaat
gagaggatgccacctcgcagagatgccatgccctctgacgccaaccttaactccatcaac
aaggctctcacctcagagactaacggcacggacagcaatggcagtaatagcagcaatatt
cagtga

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