Pan paniscus (bonobo): 100978824 Help Entry 100978824         CDS       T02283                                  Symbol OBSCN Name (RefSeq) obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism pps  Pan paniscus (bonobo) Pathway pps04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:pps00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     100978824 (OBSCN)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pps01001]     100978824 (OBSCN)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pps04131]     100978824 (OBSCN) Enzymes [BR:pps01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      100978824 (OBSCN) Protein kinases [BR:pps01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    100978824 (OBSCN) Membrane trafficking [BR:pps04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     100978824 (OBSCN) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase Ig_5 PK_Tyr_Ser-Thr Ig_4 C1-set C2-set_2 Izumo-Ig SOS1_NGEF_PH fn3 RhoGEF PH Ig_DSCAM-DSCAML_C ABC1 IQ Motif Other DBs NCBI-GeneID:  100978824 NCBI-ProteinID:  XP_054960594 Ensembl:  ENSPPAG00000039604 LinkDB All DBs Position 1:complement(21227144..21396608) Genome browser AA seq 8932 aa AA seqDB search MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQ DGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIR VREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGG TYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPP STGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILF CKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPS TEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQG NLLRKLPRKTAVRVGDTAMFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTIS QCCLEDVGQVAFMAGDCRTSTQFCVSAPRKPPLQPPVDPVVKARTESSVILSWSPPPHGE RPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPY LEFPGTVHLAPKLAVRTPLKAVQAVEGGEVTFSVDLTVASAGEWFLDGQALKASSVYEIH CDRTRHTLTIREVPASLHGAQLKFVANGIESSIRMEVQAAPGLTANKPPAAAAREVLARL HEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRWVLLVRDVARDDAGLYECVS RGGRIAYQLSVQGLACFLHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGHS GERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFQLRVSEPKAVFAKEQPVRREV QAEAGASATLSCEVAQDQMEVTWYKDGKKLSSSSKVHVEALGCMRRLVVQQAGQADSGEY SCEARGQRVSFRLDVAEPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVTWYKDGK KLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKEPKVVFAKDQVA HSEVQAEAGASATLSCEVAQAQTEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTD AGDYSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEVGASAMLSCEVAQAQTEVTWY KDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAK EQSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLIVQQV GKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQTE VMWYKDGKKLSSSSKVRVEAAGCIRQLVVQQAGRADAGEYTCEAGGQRLSFHLDVSEPKA VFAKEQLAHRKVQAKAGAIATLSCEVAQAQTEVTWYKDGKKLSSSLKVRMEAVGCTRRLV VQQACQADTGEYSCEARGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASATLSCEVAQ AQTEVMWYKDGKKLSSSSKVRMEAVGCTRRLVVQQAGQADAGEYSCEAGSQRLSFHLHVA EPKAVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVHVEAAGCT RRLVVQQAGQADTGEYSCEAGGQQLSFRLQVAEPKAVFAKEQPASREVQAEAGTSATLSC EVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQVDAGEYSCEAGGQRLSFH LHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVMWYKDGKKLSSSSKVRVEA VGCTRRLVVQQAGQAEAGEYSCEAGGQQLSFRLQVAEPKVVFAKEQAVFAKDQPAHREVQ AEAGTSTMLSCEVAQAQTEVMWYKDGKKLSSSSKMGVEAVGCTRRLVVQEAGQADAGEYS CEAGGQRLSFHLHVAEPKVVFAKEQPACREVQAEAGASATLSCEVAQGQMEVTWYKDGKK LSSSSKVRMEASGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLHMAELEPQISERPCRR EPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLD SAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEPVCGELGGTVTLACELSPACAEVVWRCGN TQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGL STVVAEEGGEATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDA GQITVEAEGASSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNAT ALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQA VEAREQGTATMEVQLSHADVEGSWTRDGLRLQQGPTCHLAVRGPMHTLTLSGLRPEDSGL MVFKAEGVHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVEL RAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGRNIQIVRPLEDVE VMEKDGATFSCEVSHDEVPGQWFWEGSKLRPTDNVRIRQEGRTYTLIYRRVLAEDAGEIQ FVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGSQELQP GPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGDVKTSAQFFVEEQSITIVRGLQDVTVM EPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHF TIGKSRSSARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPS EKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTVEAREVTVTGPLQDAEATE EGWASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRASS LKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSNPEAHVVWRKDGVQLGPSDK YDFLHTAGTRGLVVRDVSPEDAGLYTCHVGSEETRARVSVHDLHVGITKRLKTMEVLEGE SCSFECVLSHESASDPAMWTVGGKTVSSSSRFQATRQGRKYILVVREAAPSDAGEVVFSV RGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKSQK YDVVCEGTMAMLVIRGASLKDAGEYTCEVEASKSTASLHVEEKANCFTEELTNLQVEEKG TAVFTCKTEHPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQ AQSQAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHVNELN EIDAQPGGYHVLTLRQLALKDSGTIYFEAGDQRASAALRVTEKPSVFSWELTDATITEGE DLTLVCETSTCDIPVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGG ACSSSIVRVHARPVRFQEALKDLEVLEGGAATLRCVLSSVAAPVKWCFGNNVLRPGDKYS LRQEGAMLELVVRNLRPQDSGRYSCSFGDQTTSATLTVTALPAQFIGKLRNKEATEGATA TLRCELSKAAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERT SASLTIRPMPAHFIGRLRHQESTEGATATLRCELSKAAPVEWRKGRESLRDGDRHSLRQD GAVCELQICGLAMADAGEYSCVCGEERTSATLTVKALPAKFTEGLRNEEAMEGATAMLWC ELSKVAPVEWRKGPENLRDGDRYILRQEGTRCKLQICGLAMADAGEYLCVCGQERTSATL TIRALPARFIEDVKNQEAREGSTAVLQCELNSAAPVEWRKGSETLKDGDRYSLRQDGTKC ELQIRGLAMADTGEYLCVCGQERTSAMLTVRALPIKFTEGLRNEEATEGATAMLRCELSK MAPVEWWKGHEILRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVTA MPSKFIEGLRNEEATEGDTATLRCELSKAAPVEWRKGHETLRDGDRHSLRQDGSRCELQI RGLAVVDAGEYSCVCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQCELSKAAPV EWRKGSETLRGGDRYSLRQDGTRCELQIRGLSVADAGEYSCVCGQERTSATLTIRALPAR FTQDLKTKEASEGATATLQCELSKVAPVEWKKGPETLRDGGRYSLKQDGTRCELQIHDLS VADAGEYSCMCGQERTSATLTIRALPARFTEGLRNEEAMEGATATLQCELSKAAPVEWRK GLEALRDGDKYSLRQDGAVCELQIHGLAMADNGVYSCVCGQERTSATLTVRALPARFIED MRNQKATEGATVTLQCKLRKAAPVEWRKGPNTLKDGDRYSLKQDGTSCELQIRGLVIADA GEYSCICEQERTSATLTVRALPARFIEDVRNHEATEGATAVLQCELSKAAPVEWRKGSET LRDGDRYSLRQDGTRCELQIRGLAVEDTGEYLCVCGQERTSATLTVRALPARFIDNMTNQ EAREGATATLHCELSKVAPVEWRKGPETLRDGDRHSLRQDGTRCELQIHGLSVADAGEYS CMCGQERTSATLTIRALPAKFTKGLRNEEATEGATAMLQCELSKVAPVEWRKGPETLRDG DRYNLRQDGTRCELQIHGLSVADTGEYSCVCGQEKTSATLTVKAPQPVFREPLQSLQAEE GSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLRDLQREDTGEYTCTC GSQATSATLTVTAAPVRFLRELQPQEVDEGGTAHLRCELSRAGASVEWRKGSLQLFPCAK YQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKFKTRLQSLEQETGD IARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYACVT GGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNE VTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNRASSAQLTVRAPEVTILEPLQDVQLSE GQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDAGTISF HVGTCSSEAQLKVTAKNTVVRGLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVRTS ENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDMVTSAFLTVRGWRLEILEPLKNAAV RAGAQAHFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGE VTFACRDAVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKE GATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPV PPQPSAPESRQVAAGEDVCLELEVVAEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIK GFTAEDQGEYHCGLAQGSICPAAATFQVALSPASVDEAPPQPSLPPEAAQEGDLHLLWEA LARKRRMSREPTLDSISELPEEDGRSQRLPQEAEEVAPDLSEGYSTADELARTGDADLSH TSSDDESRAGTPSLVTYLKKAGRPGTSPLASKVGAPAAPSVKPQQQQEPLAAVRPPLGDL STKDLGDPSMDKAAVKIQAAFKGYKVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVA SKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLGRADAGCYTCQVSNKFGQVVH SACVVVSGTESEAESSSGGELDDTFRRAARRLHRLFCTKSPAEVSDEELFLSADEGPAEP EEPADWQTYREDEHFICIRFEALTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMRI SKETPAPVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKD GKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTD YDTAADATESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQL KVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAA YSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPAPTV HWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSA SLHVSGLPKVEEQEKVKEALISTFLQGTTQAISAQGLETASFADLDGQRKEEPLAAKEAL GHLSLTEVGTEEFLQKLTSQITEMVSAKITQAKLQVPGGDSDEDSKTPSASPRHGRSRPS SSIQESSSESEDGDARGEIFDIYVVTADYLPLGAEQDAIALREGQYVEVLDAAHPLRWLV RTKPTKSSPSRQGWVSPAYLDRRLKLSPEWGAAEAPEFPGEAVSEDEYKARLSSVIQELL SSEQAFVEELQFLQSHHLQHLERCPHVPAAVAGQKAVIFRNVRDIGRFHSSFLQELQQCD TDDDVAMCFIKNQAAFEQYLEFLVGRVQAESVVVSTAIQEFYKKYAEEALLAGDPSQPPP PPLQHYLEQPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSL MENYPGTLEALGEPIRQGHFIVWEGAPGARMPWKGHNRHVFLFRNHLVICKPRRDSRTDT FSYVFRNMMKLSSIDLNDQVEGDDRAFEVWQEREDSVRKYLLQARTAIIKSSWVKEICGI QQRLALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKPVQVDPHHIL IEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPFVEG EDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAAGKEDLGLYEC ELVNRLGSARASAELHIQSPTLQAREQCHREQLVAAVEDTTLERADQEITSVLKRLLGPK APGPSTGDLTGPGPCPRGAPALQETSSQPPVTRTSEAPAMPPRVPQPLLHKGPEQEPEAI ARAQEWTVPIRMEGAAWPGAGTGELLWGVHSHVVTETTQRTYTYQAIDTHTARPPSMQVT IEDVQAQTGGTAQFKAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASK DAGVYTCLAQNAGGQVLCKAELLVLGGDNELDSEKQNHRRKLHSFYEVKEEIGRGVFGFV KRVQHKGNKILCAAKFIPLRSRTRAQAYRERDILAALSHPLVTGLLDQFETRKTLILILE LCSSEELLDRLFRKGVVTEAEVKVYIQQLVEGLHYLHSHGVLHLDIKPSNILMVHPARED IKICDFGFAQNITPAELQFSQYGSPEFVSPEIIQQNPVSEASDIWAMGVISYLSLTCSSP FAGESDRATLLNVLEGRVSWSSPMAAHLSEDAKDFIKATLQRAPQARPSAAQCLSHPWFL KSMPAEEAHFINTKQLKFLLARSRWQRSLMSYKSILVMRSIPELLQGPPDSPSLGVARHL CRDTGGSSSSSSSSDNELAPFARAKSLPPSPVTHSPLLHPRGFLRPSASLPEEAEAGEHS TEAPAPPASPEGAGPPAAQGCVPRHSVIRSLFYQQAGESPEHGALALGSRRHPARRRHLL KGGYIAGALPGLREPLMEHRVLEEEAAREEQATLLAKALSFETAPRLPASGTHLAPGHSH SLEHESPSTPRPSSEAFGEAQRLPSAPSGGAPIRDMGHTQGSKQLPSTGGHPGTAQPERP SPDSPWGQPAPFCHPKQGSAPQEGCSPHPAVVPCPPGSFPPGSCKEAPLVPSSPFLGQPQ APPAPAKASPPLDSKMGPGDISLPGRPKPGPCSSPGSASQASSSQVSPLRVGSSQVGSSQ VGTEPGPSLDAEGWSQEAEDLSDSTPTLQRPQEQATMRKFSLGGRGGYAGVAGYGTFAFG GDAGGMLGQGPMWARIAWAVSQSEEEEQEEARAESQSEEQQEEARAESPLPQVCARPVPE VGRAPARSSPEPTPWEDIGQVSLVQIRDLSGDAEAADTISLDISEVDPAYLNLSDLYDIK YLPFEFMIFRKVPKSAQPEPPSPMAEEELAEFPEPTWPWPGELGPHAGLEITEEPEDVDA LLAEAAVGRKRKWSSPSRSLFHFPGRHLPLDEPAELGLRERVKASVEHISRILKGRPEGL EKEGPPRKKPGLASFRLSGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATW SKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTATTTGVLRKAER PSSSPCPDIGEVYADGVLLVWKPVESYGPVTYIVQCSLEGGSWTTLASDIFDCCYLTSKL SRGGTYTFRTACVSKAGMGPYSSPSEQVLLGGPSHLASEEESQGRSAQPLPSTKTFAFQT QIRRGRFSVVRQCWEKASGRALAAKIIPYHPKDKTAVLREYEALKGLRHPHLAQLHAAYL SPRHLVLILELCSGPELLPCLAERASYSESEVKDYLWQMLSATQYLHNQHILHLDLRSEN MIITEYNLLKVVDLGNAQSLSQEKVLPSEKFKDYLETMAPELLEGQGAVPQTDIWAIGVT AFIMLSAEYPVSSEGARDLQRGLRKGLVRLSRCYAGLSGGAVAFLRSTLCAQPWGRPCAS SCLQCPWLTEEGPACSRPAPVTFPTARLRVFVRNREKRRALLYKRHNLAQVR NT seq 26799 nt NT seq  +upstreamnt  +downstreamnt atggatcagccacagttcagcggggcgccccgctttctcacccggcccaaggccttcgtg gtgtcggtgggcaaggacgccaccctcagctgccagatcgtgggtaatcccacgccacag gtgagctgggagaaggaccagcagccggtggcggccggcgcgcgcttccgtctggcccag gacggcgacctctaccgcctcactatcctggacctggcgctgggcgacagtgggcaatac gtgtgccgcgcgcgcaatgccataggcgaggccttcgctgccgtgggcctgcaggtggac gcggaggccgcgtgcgccgagcaggcgccgcacttcctgctgcggcccacgtccatccgc gtgcgcgagggctcagaggccaccttccgctgccgcgtgggtggctccccgaggccggca gtgagctggtccaaggacgggcggcgcctgggtgagcccgacggcccccgcgtgcgcgtg gaggagctcggcgaggcgagtgcgctgcgcattcgggcggcgcggccgcgcgacggcggc acttacgaggtccgcgccgagaacccgctgggcgctgccagcgccgccgcggcgctagtg gtggactcggacgccgcggacacggccagccggcccgggacctccacggccgcgctcctg gcgcacctgcagcggcggcgcgaggctatgcgcgccgagggcgcccccgcctcaccgccc agcaccggcacgcgcacctgcacggtgactgaaggcaagcacgcgcgcctcagctgctac gtgaccggcgagcccaagcccgagacggtgtggaagaaggacggccagctggtgaccgag ggccggcgccacgtggtgtacgaggacgcgcaggagaacttcgtgctcaagatcctcttc tgcaagcagtcggaccgcggcctctacacctgcacggcgtccaacctcgtgggccagacc tacagctctgtgctggtcgtagtgcgcgagcccgcggttcccttcaaaaagcggctgcaa gatctagaggtgcgggagaaggagtcggccacgttcctgtgcgaggtgccccagccgtcc actgaggccgcgtggttcaaggaggagacgcggttgtgggcgagcgccaagtacggcatc gaggaggagggcaccgagcgccgcctgaccgtgcgcaatgtctcggccgacgacgacgcg gtgtacatctgcgagacgccagagggcagccgcacggtggcggagctcgcagtccaagga aacctcctccgaaagctccctcggaagacggcggtgcgcgtgggcgacacggctatgttt tgcgtggagctggcggtcccggtgggccccgtccactggctgcggaaccaggaggaagtg gtggccgggggccgcgtggccatctccgcggagggcacgcgccacacactgaccatctcc cagtgctgcctggaggatgtgggccaggtggcctttatggctggcgactgccggacgtcc acccagttctgcgtgtcggcccccaggaagcctcccctgcaaccccctgtggatcctgtg gtaaaggccaggacggagagttccgtgattctcagctggtccccaccaccccatggggaa cgccctgtcactatcgacggctacctggtagagaagaagaagcttggcacctacacctgg atcaggtgccacgaggctgaatgggtggctacacctgagctgaccgtggctgatgtggcg gaggaggggaacttccagttccgagtgtcagctctcaacagctttggtcagagtccctac ctcgagttcccggggactgtccacctggcccccaagctggccgtgaggacaccgctgaag gcggtgcaggcggtagagggtggcgaggtcactttctccgtggacctcacggtggcctca gcgggtgagtggttcctggatgggcaggccctgaaggccagcagtgtgtatgagatccac tgtgatcgcacccggcacacgctcaccatccgggaggtgcccgccagcctgcacggggcg cagctgaagttcgtggccaacggcattgagagcagcatccggatggaggtccaggcggcc ccagggctgactgccaacaagccgccagccgcagctgcccgggaggtgctggctcggctg cacgaggaggcgcagctgctggctgagctgtcagatcaggctgcggctgtgacatggctg aaggatggtcgcacactgtccccaggccccaagtatgaggtgcaggcatcggccgggcgg tgggtgctccttgtgcgagatgtggcccgggacgatgcaggcctctacgagtgcgtcagc cgcgggggccgcatcgcctaccagctgtccgtgcaaggcctcgcgtgctttctgcacaag gacatggcgggcagctgtgtggatgccgtggctgggggcccagcgcagtttgagtgtgag acctctgaagcccacgtccacgtgcactggtacaaggatggcatggagctgggccactct ggtgagcgcttcttgcaggaggatgtggggacgcggcaccggctggtggcagccacagtc accaggcaggatgagggcacctactcctgccgcgtgggcgaggactctgtggacttccag ctccgcgtctctgagcccaaggcggtgtttgccaaggagcagccggtgcgcagggaggtg caggctgaggcgggggccagtgccacgctgagctgtgaggtggcccaggaccagatggag gtgacgtggtacaaggacgggaagaagttgagctccagctcgaaagtgcacgtggaggct ttgggctgtatgcggaggctggtggtgcagcaggcgggccaggcagactccggagagtac agctgtgaggccaggggacagagggtctccttccgcctggacgttgcagaacccaaggtg gtgtttgctaaggagcagctggcacgcaggaagctgcaggcagaggcaggagccagtgcc acactgagctgcgaggtggcccaggcccagacggaggtgacatggtacaaggatgggaag aagctgagctccagctcgaaagtgtgcatggaggccacaggctgcacgcgcaggctggtt gtgcagcaggcaggccaggcggatgccggggagtatagctgcgaggctgggggccagcgg ctctccttccatctggacgtcaaagagcccaaggtggtgtttgccaaggaccaggtggca cacagtgaggtgcaggctgaggcaggggccagtgccacgctgagctgcgaggtggcccag gcccagacggaggtgatgtggtacaaagatgggaagaagctgagctccagcttgaaagtg catgtggaggccaagggctgcagacggaggctggtggttcagcaggcaggcaagacggat gccggggactacagctgcgaggccaggggccagagggtctccttccgcctgcacatcaca gagcccaagatgatgtttgcaaaggagcagtcagtgcataatgaggtgcaggctgaggtg ggggccagtgccatgctgagctgtgaggtggcccaggcccagacggaggtgacgtggtac aaggatgggaagaagctgagctccagctcaaaagtgggcatggaggtcaaagggtgcaca cggaggctggtgctgccacaggcgggcaaagcagatgctggggagtacagctgtgaggct gggggccagagagtctccttccacctgcacatcacagagcccaagggggtgtttgcgaag gagcagtcagtgcataatgaggtgcaggctgaggcggggaccactgccatgctgagctgt gaggtggcccagccccagacggaggtaacgtggtacaaggacgggaagaagctgagctcc agctcaaaagtacgcatggaggtcaagggctgcacacggaggctgatagtgcagcaggtg ggcaaagcagatgctggggagtacagctgcgaggctgggggccagagagtctcctttcaa ctgcacatcacagagcccaaggcagtgtttgccaaggagcagttggtgcataatgaggtg cggactgaggcaggggccagtgccacactgagctgtgaggtggcccaggcccagacagag gtgatgtggtacaaggatgggaagaagctgagctccagttcgaaagtgcgcgtagaggcc gcgggctgcatacggcagctggtggtgcagcaggcaggccgggcagatgctggggagtac acctgtgaggctgggggccagcggctctccttccacctggatgtttcagagcccaaggcg gtgtttgcaaaggagcagctggcacacaggaaggtgcaggccaaggcgggggccattgcc acgctgagctgcgaggtggcccaggcccagacagaggtgacgtggtacaaggacgggaag aagctgagctccagcttgaaagttcgaatggaggctgtgggctgcacacggaggctggtg gtgcagcaggcatgccaggcggacaccggggagtatagctgcgaggccaggggccagcgg ctctccttcagcctggacgtggcagagcccaaggtggtgtttgccaaggagcagccggtg cacagggaggtgcaggcccaggcgggggccagcgccacactcagctgcgaggtggctcag gcccagacggaggtgatgtggtacaaggacgggaagaagctgagctccagctcgaaagtg cgcatggaggctgtgggctgcacacggaggctggtggtgcagcaggcgggccaggcggac gccggggagtacagctgcgaggcggggagccagcggctctccttccacctgcatgtggca gagcccaaggcggtgtttgctaaggagcagccagcacacagggaggtgcaggctgaagca ggggctagcgccacactgagctgtgaggtggcccaggcccagacagaggtgacttggtac aaggacgggaagaagctgagctccagctcgaaagtgcatgtggaggctgcaggctgtaca cggaggctggtggtgcagcaggcaggccaggcagacaccggagagtatagctgtgaggct gggggccagcagctctccttccgcctgcaagtggcagagcccaaggcggtgtttgccaag gagcagccagcgagcagggaggtgcaggccgaggcggggaccagtgccacgctgagctgc gaggtggcccaagcccagacagaggtgacgtggtacaaggacgggaagaaactgagctcc agctcgaaagtgcgaatggaggccgtgggctgcacacggaggctggtggtgcaggaggca ggccaggtggacgccggagagtacagctgcgaggccgggggtcagcggctgtccttccac ctgcacgtggcagagcccaaggtggtgtttgccaaggagcagccagcacacagggaggtg caggctgaggcgggggccagtgccacgctgagctgcgaggtggcccaggcccagacagag gtgatgtggtacaaggatgggaagaagctgagttccagctcgaaagtgcgcgtggaggcc gtgggctgcacacggaggctggtggtgcagcaggcgggccaggcagaggccggggagtac agctgcgaggcagggggtcagcagctctccttccgcctgcaggtggcagagcccaaggtg gtgtttgccaaggagcaggcggtgtttgccaaggatcagccggcgcacagggaggtgcag gctgaggcagggaccagcaccatgctgagctgcgaggtggcccaagcccagacggaggtt atgtggtacaaggacgggaagaagctgagctccagctcgaaaatgggtgtggaggccgtg ggctgcacacggaggctggtggtgcaggaggcaggccaggcggatgccggggagtacagc tgcgaggctgggggccagcggctctccttccacctgcatgtggctgagcccaaggtggtg tttgccaaggagcagccggcatgcagggaggtgcaggcggaggcgggggccagtgccacg ctgagctgtgaggtggcccagggccagatggaggtgacatggtacaaggatgggaagaag ctgagctccagctcaaaagtgcgcatggaggccagcggctgcacacggaggctggtagtg cagcaggcgggccaggcggatgctggggagtacagctgtgaggcggggggccaacggctg tccttccgcctgcacatggcagagctggagccccaaatttcagagagaccctgccgcagg gagcctctggtggtcaaggagcatgaagacatcatcctgaccgccacactggccacaccc tctgcggccacggtgacctggctcaaggatggtgtggagattcgccgcagcaagcggcat gagacagccagccagggggacacccacaccctgaccgtgcatggcgcccaggttctggac agcgccatctacagctgccgtgtgggcgcagaggggcaggacttcccagtgcaggtggaa gaggtggccgccaagttctgccggctgctggagcctgtgtgcggcgagctgggcggcacg gtgacactggcctgcgagctaagcccagcgtgtgcagaggtggtgtggcgctgcggcaac acacagcttcgggtgggcaagcgcttccagatggtggccgaggggcccgtgcgctcactc actgtgttggggctgcgcgcagaggacgcaggggagtacgtgtgtgagagccgtgatgac cacaccagtgcgcagctcaccgtcagtgtgccccgagtggtgaagtttatgtctgggctg agcaccgtggtcgcagaggagggtggcgaggccaccttccagtgcgtggtgtcccccagt gatgtggcagtcgtgtggttccgggacggtgccctgcttcagcccagcgagaagtttgcc atatcacagagtggcgccagccacagcctgaccatctcagacctggtgctggaggacgcg ggccagatcaccgtggaggctgagggcgcctcatcctctgctgccctgagggtccgagag gcgcctgtgctgttcaaaaagaagctggagccgcagacggtggaggagcggagctcggtg accctggaggtggagctgacgcggccgtggccggagctgaggtggacacggaacgcgacg gccctggcgccgggaaagaacgtggagatccacgccgagggcgcccgccaccgcctggtt ctgcacaacgtaggttttgccgaccgtggcttctttggctgcgagacgccggatgacaag acacaggccaaactcaccgtggagatgcgccaggtacggctcgtacggggcctgcaggca gtggaggcacgggagcagggcacagctaccatggaggtgcagctgtcgcatgcggacgtg gagggcagctggactcgtgacggtctgcggctccagcaggggcccacgtgccacctggct gtgcggggccccatgcacaccctcacactctcggggctgcggccagaggatagtggcctt atggtcttcaaggccgaaggagtgcacacgtcggcgcggctcgtggtcaccgagcttccc gtgagcttcagccgcccgctgcaggacgtggtgaccactgagaaggagaaggttaccctg gagtgcgagctgtcacgtcctaatgtggatgtgcgctggctgaaggacggtgtggagctg cgggcaggcaagacgatggccatcgcagcccagggcgcctgcaggagcctcaccatttac cggtgcgagttcgcggatcagggagtgtatgtgtgtgatgcccatgatgcccagagctct gcctccgtgaaggtacaaggccgcaacatccagatcgtgaggcccctggaggatgtggaa gtgatggagaaggacggtgccaccttctcctgtgaagtctcccacgacgaagtgcctggc cagtggttctgggagggcagtaaactgcggcctactgacaacgtgcgcatccgccaggaa ggaaggacatacactctcatctaccggagagtcctagcggaagatgcaggagagatccaa tttgtagccgaaaatgcagaatcgcgagcccagctccgagtgaaggagctgccagtgacc ctcgtgcgcccgctgcgggacaagattgccatggagaagcaccgcggtgtgctggagtgt caggtgtcccgggccagcgcccaggtgcggtggttcaagggcagtcaggagctgcagccc gggcccaagtacgagctggtcagtgatggcctctaccgcaagctgatcatcagtgatgtc cacgcagaggacgaggacacctacacctgtgacgccggtgatgtcaagaccagtgcacag ttcttcgtggaagagcaatccatcaccattgtgcggggtctgcaggacgtgacagtgatg gagcccgctcctgcctggtttgagtgtgagacctccatcccctcagtgcggccacctaag tggctcctggggaagacggtgttgcaggctggggggaacgtgggcctggagcaggagggc acggtgcaccggctgatgctgcggcggacctgctccaccatgaccgggcccgtgcacttc accattggcaagtctcgctcctctgcccgcctggtggtctcagacatccccgtagtcctc acacggccgttggagcccaagacagggcgtgagctgcagtcagtggtcctgtcctgcgac ttccggccagcccccaaggctgtgcagtggtacaaggatgacacgcccctgtctccctct gagaagtttaagatgagcctggagggtcagatggctgagctgcgcatcctccggctcatg cctgccgatgctggtgtctaccggtgccaggcgggcagcgcccacagcagcactgaggtc actgtggaagcgcgggaggtgacagtgacagggccgctgcaggatgcagaggccacggag gagggctgggccagcttctcctgtgagctgtcccacgaggatgaggaggtcgagtggtcg ctcaacgggatgcccctgtacaatgacagcttccatgagatctcacacaagggccggcgc cacacgctggtactgaagagcatccagcgggctgatgcgggcatagtacgcgcctcctcc ctgaaggtgtcgacctctgcccgcctggaggtccgagtgaagccggtggtgttcctgaag gcgctggatgacctgtccgcagaggagcgcggcaccctggccctgcagtgtgaagtctct aaccctgaggcccatgtggtgtggcgcaaagatggcgtgcagctgggccccagtgacaag tatgacttcctgcacacggcaggcacgcgggggctcgtggtgcgtgacgtgagccctgaa gacgccggcctgtacacctgccacgtgggctccgaggagacccgggcccgggtcagcgtg cacgatctgcacgtgggcatcaccaagaggctgaagacaatggaggtgctggaaggggag agctgcagctttgagtgcgtcctgtcccatgagagcgccagcgacccggccatgtggaca gtcggtgggaagacagtgagcagctccagccgcttccaggccacacgtcagggccgaaaa tacatcctggtggtccgggaggctgcaccaagtgatgccggggaggtggtcttctctgtg cggggcctcacctccaaggcctcactcattgtcagagagaggccggccgccatcatcaag cccctggaagaccagtgggtggcgccaggggaggacgtggagctgcgctgtgagctgtca cgggcgggaacgcccgtgcactggctgaaggacaggaaggccatccgcaagagccagaag tatgatgtggtctgcgagggcacgatggccatgctggtcatccgcggggcctcgctcaag gacgcgggcgagtacacgtgtgaggtggaggcttccaagagcacagccagcctccatgtg gaagaaaaagcaaactgcttcacagaggagctgaccaatctgcaggtggaggagaaaggc acagctgtgttcacgtgcaagacggagcaccccgcggccacagtgacctggcgcaagggc ctcttggagctacgggcctcagggaagcaccagcccagccaggagggcctgaccctgcgg ctcaccatcagtgccctggagaaggcagacagcgacacctatacctgcgacattggccag gcccagtcccaggcccagctcctagtgcaaggccggagagtgcacatcatcgaggacctg gaggatgtggatgtgcaggagggctcctcggccaccttccgttgccggatctccccggcc aactacgagcctgtgcactggttcctggacaagacacccctgcatgtcaacgagctcaat gagatcgatgcccagcccgggggctaccacgtgctgaccctgcggcagctggcgctcaag gactcgggcaccatctactttgaggcgggtgaccagcgggcctcggccgccctgcgggtc actgagaagccaagcgtcttctcctgggagctcacagatgccaccatcacagagggtgag gacttgaccctggtgtgcgagaccagcacctgcgacattcctgtgtgctggaccaaggat gggaagaccctgcgggggtctgcccggtgccagctgagccatgagggccaccgggcccag ctgctcatcactggggccaccctgcaggacagtggacgctacaagtgtgaggctgggggc gcctgcagcagctccattgtcagggtgcatgcgcggccagtgcggttccaggaggccctg aaggacctggaggtgctggagggtggtgctgccacactgcgctgtgtgctgtcatctgtg gctgcgcccgtgaagtggtgctttggaaacaacgtcctgaggccaggtgacaaatacagc ctacgccaggagggtgccatgctggagctggtcgtccggaacctccggccgcaggacagc gggcggtactcatgctccttcggggaccagactacttctgccaccctcacagtgactgcc ctgcctgcccagttcatcgggaaactgagaaacaaggaggccacagaaggggccacggcc acgctgcggtgtgagctgagcaaggcagcccctgtggagtggagaaaggggtccgagacc ctcagagatggggacagatactgtctgaggcaggacggggccatgtgtgagctgcagatc cgtggcctggccatggtggatgccgcggagtactcgtgtgtgtgtggagaggagaggacc tcagcctcactcaccatcaggcccatgcctgcccacttcataggaagactgagacaccaa gagagcacagaaggggccacagccacgctgcggtgtgagctgagcaaggcggcccccgtg gagtggaggaaggggcgtgagagcctcagagatggggacagacacagcctgaggcaggac ggggctgtgtgcgagctgcagatctgtggcctggctatggcagatgctggggagtactcc tgtgtgtgtggggaggagaggacgtctgccactctcaccgtgaaggccctgccagccaag ttcacagagggtctgaggaatgaagaggccatggaaggggccacagccatgttgtggtgt gaactgagcaaggtggcccctgtggagtggaggaaggggcccgagaacctcagagatggg gacagatacatcctgaggcaggaggggaccaggtgtaagctgcagatctgtggcctggcc atggcggacgccggggagtacttgtgtgtgtgcgggcaggagaggacctcagccacgctc accatcagggctctgcctgccaggttcatagaagatgtgaaaaaccaggaggccagagaa gggtccacggctgtgctgcagtgtgagctgaacagtgcagcccctgtggagtggaggaag gggtctgagacccttaaagatggggacagatacagcctgaggcaggacgggaccaaatgt gagctgcagattcgtggcctggccatggcagacactggggagtacttgtgcgtgtgcggg caggagaggacctcggctatgctcaccgtcagggctctacccatcaagttcacagagggt ctgaggaacgaagaggccacagaaggggcaacggccatgctgcggtgtgagctgagcaag atggcccccgtggagtggtggaaggggcatgagatcctcagagatggagacagacacagc ctgaggcaggacggggccaggtgtgagctgcagatccgcggcctcgtggcagaggacgct ggggagtacctgtgcatgtgcgggaaggaaaggacctcagccatgctcactgtcacggcc atgccttccaagttcatagagggtctgaggaatgaagaggccacagaaggggacacggcc acgctgcggtgtgagctgagcaaggcggcaccggtggagtggaggaaggggcatgagacc ctcagagacggggacagacacagcctgaggcaggacgggtccaggtgtgagctgcagatc cgtggcctggctgtggtggatgccggggagtactcgtgtgtgtgcgggcaggagaggacc tcagccacactcactgtcagggccctgcctgccagattcatagaagatgtgaaaaaccag gaggccagagaaggggccacggccgtgctgcaatgtgagctgagcaaggcggcccccgtg gagtggaggaaggggtctgagaccctcagaggtggggacagatacagcctgaggcaggat gggaccagatgtgagctgcagattcgtggcctgtccgtggcagacgctggggagtactcg tgtgtgtgcgggcaggagaggacctcggccacactcaccatcagggccctgcctgcacga ttcactcaagatctgaagaccaaggaggcctcagaaggggccacagctacactgcagtgt gagctgagcaaggtggcccctgtggaatggaagaagggtcctgagaccctcagagatggg ggcagatacagcctgaagcaggatgggacgaggtgtgagctgcagatccatgacctgtct gtggcggatgctggggaatactcatgcatgtgtggacaagagaggacctcggccacactc accatcagggccctgcctgccaggttcacagagggtctgaggaatgaagaggccatggaa ggggccacagccacactgcaatgtgagctgagcaaggcagcccctgtggagtggaggaaa ggccttgaggctctcagagatggggacaaatacagcctgagacaagacggggctgtgtgt gagctgcagattcatggcctggctatggcagataacggggtgtactcatgtgtgtgtggg caggagaggacctcagctacactcactgtcagggccctgcctgccagattcatagaggat atgagaaaccagaaggccacagaaggggctacagtcacactgcaatgtaagctgagaaag gcggcccccgtggagtggagaaaggggcccaacaccctcaaagatggggacaggtacagc ctgaagcaggatgggaccagttgtgagctgcagattcgtggcctggtcatagcagatgct ggagaatactcgtgcatatgtgagcaggagaggacctcggccacgctcactgtcagggcc ctgccggccagattcatagaagatgtgagaaatcacgaggccacagaaggggccacagct gtgctgcagtgtgagctgagcaaggcggcccccgtggagtggcggaaggggtctgagacc ctcagagatggggacagatatagcctgaggcaggacgggacgaggtgtgagctgcagatt cgtggcctggctgtggaggacactggagagtatttgtgtgtgtgcgggcaggagagaacc tcagctacactcactgtcagggccctgccagccagattcatagacaacatgacaaaccag gaggccagagaaggggccacggccacactgcactgtgaactgagcaaggtggcccctgtg gagtggaggaagggacctgaaaccctccgagatggggacagacacagcctgaggcaggat gggaccaggtgtgagctgcagattcatggcctgtctgtggcagatgccggggagtactcg tgcatgtgtgggcaggagaggacctcagccacactcacgatcagggccctgcccgccaag ttcacaaagggtctgaggaatgaagaggccacagaaggggccacggctatgttgcagtgt gagctgagcaaggtggcccctgttgagtggaggaagggacctgaaaccctcagagatggg gacagatacaacctgaggcaggatgggaccagatgtgagctgcagattcatggcctgtcc gtggcagacactggggagtactcatgtgtatgtggtcaggagaagacgtcggccactctc actgtcaaggccccacagccagtgttccgggagccgctgcagagtctgcaggcggaggag ggctccacggccaccctgcagtgtgagctgtctgagcccactgctacagtggtctggagc aagggtggcctgcagctgcaggccaatgggcgccgggagccacggcttcagggctgcacc gcggagctggtgttacgggacctacaacgtgaagacactggcgaatacacttgcacctgt ggctcccaggccaccagtgccaccctcactgtcacagctgcgcctgtgcggttcctccga gagctgcagccccaggaggtggatgagggaggcactgcacacttacgctgcgagctgagc cgggcgggtgcgagcgtggagtggcgcaagggctccctacagctcttcccttgtgccaag taccagatggtgcaggatggtgcagctgcagagctgctggtacgcggagtggagcaggag gatgcgggtgactacacgtgcgacacgggccacacgcagagcatggccagcctctctgtc cgtgtccccaggcccaagttcaagacccggcttcagagtctggagcaggagacaggtgac atagcccggctgtgctgtcagctgagtgatgcagagtcgggggccgtggtgcaatggctc aaggagggcgtggagctgcatgcaggccccaagtacgagatgcggagccagggggccacg cgggagctgctgatccaccaactggaggccaaggacacgggcgagtatgcctgtgtgaca ggcggccagaaaaccgctgcctccctcagggtcacagagcctgaggtgaccattgtacgg gggctggttgatgcggaggtgacggccgatgaggatgttgagttcagctgtgaggtgtcc agggctggagccacaggcgtgcagtggtgcctacagggcctgccactgcaaagcaatgag gtgacagaggtggctgtgcgggatggccgcatccacaccctgcggctgaagggcgtgacg cccgaggacgctggcactgtctccttccatttgggaaaccgtgcttcctctgcccagctc accgtcagagctcctgaggtgaccatcctggagcccctgcaggacgtgcagctcagtgag ggccaggatgccagcttccagtgccggctatccagagcttcaggccaggaggcccgctgg gctttaggaggggtgcccctgcaggccaacgagatgaatgacatcactgtggagcagggc acactccacctgctcaccctgcacaaggtgacccttgaggatgctggaactatcagtttc cacgtgggcacgtgtagctctgaggcccagctgaaagtcacagccaagaacacggtggtg cgggggctggagaacgtggaggcgctggagggcggcgaggcgctgttcgagtgccagctg tcccagcccgaggtggccgcccacacctggctgctggacgacgaacccgtgcgcacctcg gagaacgccgaggtggtcttcttcgagaacggtctgcgccacctgctgctgctcaaaaac ttgcggccacaagacagctgccgggtgaccttcctggctggggatatggtgacgtccgca ttcctcactgtccgaggctggcgcctggagatcctggagcctctgaaaaacgcggcggtc cgggccggcgcgcaggcccacttcacctgcacgctcagcgaggcggtgcccgtgggagag gcgtcctggtacatcaatggcgcggcagtgcagccggatgacagcgactggactgtcacc gccgacggcagtcaccacgccctactgctgcgcagcgcccagccccaccacgccggggag gtcaccttcgcttgccgcgacgccgtggcctctgcgcggctcaccgtgctgggcctccct gatcccccagaggatgctgaggtggtggctcgcagcagccacactgtgacactatcttgg gcagctcccatgagtgatggaggcggtggtctctgtggctaccgcgtggaggtgaaggag ggggccacaggccagtggcggctgtgccacgagctggtgcctggacccgagtgtgtagtg gatggcctggcccccggggagacctaccgcttccgtgtggcagctgtgggccctgtgggt gctggggaaccggttcacctgcctcagacagtgcggcttgcagagccaccgaagcctgtg cctccccagccctcagcccctgagagccggcaggtggcagctggtgaggatgtctgtctg gagcttgaggtggtggctgaggctggcgaggtcatctggcacaagggaatggagcgcatc cagcctggtgggcggttcgaggtggtctcccagggtcggcaacagatgctggtgatcaag ggcttcacggcagaagaccagggcgagtaccactgtggcctggctcagggctccatctgc cctgcggctgccaccttccaggtggcactgagcccagcctctgtggatgaggcccctcct cagcccagcttgccccccgaggcagcccaggagggtgacctgcacctactgtgggaggcc ctggctcggaaacgtcgcatgagccgtgagcccacgctggactccattagcgagctgcca gaggaagacggccgctcgcagcgcctgccacaggaggcagaggaggtggcacctgatctc tctgaaggctactccacggccgatgagctggcccgcactggagatgctgacctctcacac accagctctgatgatgagtcccgggcaggcaccccttccctggtcacctacctcaagaag gctgggaggccaggcacctcaccactggccagcaaggttggggccccagcagccccctct gtgaagccacagcagcagcaggagccactggctgctgtgcgcccaccactgggagacctg agcaccaaagacctgggtgatccctcaatggacaaggcagctgtgaagatccaggctgcc tttaagggctacaaggtccggaaggagatgaagcagcaggaagggcccatgttctcccac acatttggggacaccgaggcacaggtgggggatgctctgcggctggagtgtgtcgtggcc agcaaggcagatgtgcgagcccgctggctgaaggatggtgtggagctgaccgatgggcgg caccatcacatcgaccagcttggggatggcacctgctctctgctgatcactggcctgggc cgtgctgatgctggctgctacacctgtcaggtgagcaacaagtttggccaggtggtccac agtgcctgtgtggtggtcagtgggacagagagtgaagccgagagctcctctgggggtgag ctggatgataccttccgccgggctgcccggcggctgcaccggctcttctgcaccaagagt ccggctgaagtttcagatgaggagctcttcctgagtgcagacgagggccctgcagagcca gaggagcccgcggactggcagacataccgcgaagatgagcatttcatctgcatccgtttt gaggcgctcactgaggcccgccaggcggtaactcgcttccaggagatgtttgccacactg ggcattggggtggagatcaagctggtggaacaggggcctcggagggtagagatgcgcatc agcaaagagacccctgcccctgtggtgcctccagagccattgcccagcctactgacttct gacgctgccccagtgttcctgactgagttgcagaaccaagaagtgcaggatgggtatcct gtgagctttgactgcgtggtgacaggtcagcccatgcccagtgtgcgctggttcaaggat gggaagttgttggaggaggatgatcactacatgattaatgaagaccaacagggtggccat cagctcatcatcacagccgtggtgccagcagacatgggcgtctaccgctgcctggccgag aacagcatgggtgtctcctccaccaaggctgagctccgtgtggacttgacaagcacagac tatgacactgcagcagatgccacggagtcctcatcctacttcagtgcccaaggctacctg tccagccgggaacaggagggaacagagtccaccactgatgagggccagctgccccaggtg gtggaggagctgagagacctccaggtggcccctggcacacgcctggccaagttccagctc aaggtgaaaggctaccctgctcccagattatactggttcaaagatggccagcccctgacc gcatctgcccacatccgcatgactgacaagaagatcctgcacaccctggagatcatctcc gtcacccgggaggactctggccagtatgcagcctacatcagcaatgccatgggtgctgcc tactcgtctgcccggctgctggttcgaggccctgatgagccagaagagaagcctgcatca gatgtgcatgagcagctggtgccgccccgaatgctggagaggttcacccccaagaaagtg aagaaaggctccagcatcaccttctctgtgaaggtagaaggacgcccggcgcccaccgtg cactggctcagggaggaggctgagagaggcgtgctgtggattggccctgacacaccgggc tacaccgtggccagctctgcgcagcagcacagcctggtcctgctggacgtgggccggcag caccagggcacctacacatgcattgccagcaacgctgccggccaggccctctgctccgcc agcctgcacgtctcgggcctgcctaaggtggaggagcaggagaaagtgaaggaagcgctg atttccactttcctgcaggggaccacacaagccatctcagcacaggggttggaaactgcg agttttgctgaccttgatgggcagaggaaagaagagcctctggctgccaaggaggccctc ggccacctgtccctcactgaggtgggcacagaggagttcctgcagaaactgacctcccag atcactgagatggtatcggccaagatcacgcaggccaagctgcaggtgcctggaggtgac agtgatgaggactccaagacaccatctgcatccccccgccatggccgatcacggccatcc tccagcatccaggagtcttcctcagagtcagaggacggcgatgcccgaggcgagatcttt gacatctacgtggtcaccgctgactacctgcccctaggggctgagcaggatgccatcgcg ctgcgggaaggccagtatgtggaggtcctggatgcagcccacccactgcgctggcttgtc cgcaccaagcccaccaagtccagcccctcacggcagggctgggtgtcaccagcctacctg gacaggaggctcaagctgtcacctgagtggggggccgccgaggcccctgagttccctggg gaggctgtgtctgaagacgaatacaaggcaaggctgagctctgtgatccaggagctgctg agttctgagcaggccttcgtggaggagctgcagttcctgcagagccaccacctgcagcac ctggagcgctgcccccacgtgcccgcagccgtggccggccagaaggcagtcatctttcgc aatgtgcgggacatcggccgcttccacagcagcttcctgcaggagctgcagcagtgtgac acggacgacgacgtggccatgtgcttcatcaagaaccaggcggcctttgagcagtacctg gagttcctggtggggcgtgtgcaggctgagtcggtggtcgtcagcacggccatccaggag ttctacaagaaatacgcggaggaggccctgttggcaggggacccctctcagcccccgcca ccacctctgcagcactacctggagcagccagtggagcgggtgcagcgctaccaggccttg ctgaaggagctgatccgcaacaaggcgcggaacagacagaactgcgcgctgctggagcag gcctatgccgtggtgtctgccctgccacagcgtgctgagaacaagctgcacgtgtccctc atggagaactacccaggcaccctggaggccttgggcgagcccatccgccagggccacttc atcgtgtgggagggtgcaccgggggcccgcatgccctggaagggccacaaccgtcacgtg ttcctcttccgcaaccacctggtaatctgcaagccccggcgagactcccgcaccgatacc ttcagctacgtgttccggaacatgatgaagctgagcagcatcgacctgaacgaccaggtg gagggggatgaccgcgccttcgaggtgtggcaggagcgggaggactcggtgcgcaagtac ctgctgcaggcacggacagccattatcaagagctcgtgggtgaaggagatctgtggcatc cagcagcgtctggccctgcctgtgtggcggcccccggactttgaagaggagctggccgac tgcacagccgagctgggtgagacagtcaagctggcctgccgcgtgacgggcacacccaag cctgtcatcagctggtacaaagatgggaaaccagtgcaggtggacccccaccacatcctc attgaagaccctgatggctcgtgtgcactcatcctggacagcctgaccggtgtggactct ggccagtacatgtgcttcgcggccagcgccgctggcaactgcagtaccctgggcaagatc ctggtgcaagtcccaccacggttcgtgaacaaggtccgggcctcaccctttgtggaggga gaggacgcccagttcacctgcaccatcgaaggcgccccgtacccgcagatcaggtggtac aaggacggagccctgctgaccactggcaacaagttccagacactgagtgagcctcgcagc ggcctgctagtgctggtgatccgggcggccggcaaggaggacctggggctctacgagtgt gagctggtgaaccggctgggctccgcgcgggctagtgcggagctgcacattcagagcccc acgctgcaggcccgggagcagtgtcacagggagcagctcgtggctgcagtggaagacacc accctggagcgagcggaccaggagatcacatctgtcctgaagagactgctgggccccaag gcgccaggcccctccacaggggacctcactggccctggcccctgccccaggggggcaccc gcactccaggaaaccagctcccagcccccagtcaccagaacttcggaggcacctgccatg cccccgagggtgccacagcccctcctccacaaaggcccagagcaggagccggaggccatt gccagagcccaggaatggactgtgcccattcggatggagggtgcagcctggcccggggca ggcacaggggagctgctctggggcgtccacagccacgtggtcacagagaccacacagagg acctacacataccaggccatcgacacgcacaccgcacggcccccatccatgcaggtaacc atcgaggatgtgcaggcacagacaggcggaacggcccaattcaaggctatcattgagggt gacccacagccctcggtgacctggtacaaggacagcgtccagctggtggacagcacccgg cttagccagcagcaagaaggcaccacatactccctggtgctgaggcatgtggcctcgaag gatgccggcgtttacacctgcctggcccaaaacgctggtggccaggtactctgcaaggca gagctgctggtgcttgggggggacaatgagctggactcagagaagcaaaaccaccggagg aagctgcactccttctatgaggtcaaggaggagattggaaggggcgtgtttggcttcgta aaaagagtgcagcacaaaggaaacaagatcttgtgcgctgccaagttcatccccctacgg agcagaactcgggcccaggcatacagggagcgagacatcctggccgcgctgagccacccg ctggtcacggggctgctggaccagtttgagacccgcaagaccctcatcctcattctggag ctgtgctcatccgaggagctgctggaccgcctgttcaggaagggtgtggtgacggaggcc gaggtcaaggtctacatccagcagctggtggaggggctgcactacctgcacagccatggc gttctccacctggacataaagccctctaacatcctgatggtgcatcctgcccgggaagac attaaaatctgcgacttcggctttgcccagaacatcaccccagcagagctgcagttcagc cagtacggctcccctgagttcgtctcccccgagatcatccagcagaaccctgtgagcgaa gcctccgacatttgggccatgggtgtcatctcctacctcagcctgacctgctcatcccca tttgccggcgagagtgaccgtgccaccctcctgaacgtcctggaggggcgcgtgtcatgg agcagccccatggctgcccacctcagcgaagatgccaaagacttcatcaaggctacgctg cagagagcccctcaggcccggcctagtgcggcccagtgcctctcccacccctggttcctg aaatccatgcctgcggaggaggcccacttcatcaacaccaagcagctcaagttcctcctg gcccgaagtcgctggcagcgttccctgatgagctacaagtccatcctggtgatgcgctcc atccctgagctactgcagggcccacccgacagcccctccctcggcgtagcccggcacctc tgcagggacactggtggctcctccagttcctcctcctcctctgacaatgagctcgcccca tttgcccgggctaagtcactgccaccctccccggtgacgcactcaccactgctgcacccc cggggcttcctgcggccctcggccagcctgcctgaggaagccgaggccggtgagcactcc accgaggccccagctccgcctgcatctcccgagggtgccgggccaccggccgcccagggc tgcgtgccccggcacagcgtcatccgcagcctgttctaccagcaggcgggtgagagccct gagcacggggcccttgccctggggagcaggcggcacccggcccggcggcggcacctgctg aagggcgggtacattgcgggggcgctgccaggcctgcgcgagccactgatggagcaccgc gtgctggaggaggaggccgccagggaggagcaggccaccctcctggccaaagccctctca ttcgagactgccccccggctgcctgcctctggcacccacttggcccctggccacagccac tccctggaacatgagtctccgagcaccccccgcccctcctcagaggccttcggtgaggca cagcgactgccttcagccccctccgggggggcccctatcagggacatggggcacactcag ggctccaagcagcttccatccactggtggccacccaggcactgctcagccagagaggcca tccccggacagcccttgggggcagccagcccctttctgccaccccaagcagggttctgcc ccccaggagggctgcagcccccacccagcagttgtcccatgccctcctggctccttccct ccaggatcttgcaaagaggcccccttagtaccctcaagccccttcttgggacagccccag gcaccccctgcccctgccaaagcaagccccccattggactctaagatggggcctggagac atctctcttcccgggaggccaaaacccggcccctgcagttccccagggtcagcctcccag gcgagctcttcccaagtgagccccctcagggtgggctcctcccaggtgggctcctcccag gtgggcacagagcctggcccctccctggacgctgagggctggtcccaggaggctgaggat ctgtccgactccacacccaccttgcagcggcctcaggaacaggcgaccatgcggaagttc tccctgggtggtcgtgggggctacgcaggcgtggctggttatggcacctttgcctttggt ggagatgcagggggcatgctggggcaggggcccatgtgggccaggatagcctgggctgtg tcccagtcggaggaggaggagcaggaggaggccagggctgagtcccagtcggaggagcag caggaggaggccagggctgagagcccactgccccaggtctgtgcaaggcctgtgcctgag gtcggcagggctcccgccaggagctctccagagcccaccccatgggaggacatcgggcag gtctccttggtgcagatccgggacctgtcaggtgatgcggaggcggccgacacaatatcc ctggacatttccgaggtggaccccgcctacctcaacctctcagacctgtacgatatcaag tacctcccattcgagtttatgatcttcaggaaagtccccaagtctgctcagccagagccg ccctcccccatggctgaggaggagctggccgagttcccggagcccacgtggccctggcca ggtgaactgggcccccacgcaggcctggagatcacagaggagccagaggatgtggacgcg ctgctggcggaggctgccgtgggcaggaagcgcaagtggtcctcgccgtcacgcagcctc ttccacttccctgggaggcacctgccgctggacgagcctgcagagttggggctgcgtgag agagtgaaggcctccgtggagcacatctcccggatcctgaagggcaggccggaaggtctg gagaaggaggggccccccaggaagaagccaggccttgcttccttccggctctcaggtctg aagagctgggaccgagcgccgacattcctaagggagctctcagatgagactgtggtcctg ggccagtcagtgacactggcctgccaggtgtcagcccagccagctgcccaggccacctgg agcaaagacggagcccccctagagagcagcagccgtgtcctcatctctgccaccctcaag aacttccagcttctgaccatcctggtggtggtggctgaggacctgggtgtgtacacctgc agcgtgagcaatgcgctggggacagcaaccaccacgggcgtcctccggaaggcagagcgc ccctcatcttcgccatgccccgatatcggggaggtgtacgcggatggggtgctgctggtc tggaagcccgtggaatcctacggccctgtgacctacattgtgcagtgcagcctagaaggc ggcagctggaccacactggcctccgacatctttgactgctgctacctgaccagcaagctc tcccggggtggcacctacaccttccgcacggcatgtgtcagcaaggcaggaatgggtccc tacagcagcccctcggagcaagtcctcctgggagggcccagccacctggcctctgaggag gagagccaggggcggtcagcccaacccctgcccagcacaaagaccttcgcattccagaca cagatccggaggggccgcttcagcgtggtgcggcagtgctgggagaaggccagcgggcgg gcgctggccgccaagatcatcccctaccaccccaaggacaagacagcagtgctgcgcgaa tacgaggccctcaagggcctgcgccacccgcacctggcccagctgcacgcagcctacctc agcccccggcacctggtgctcatcttggagctgtgctctgggcccgagctgctcccctgc ctggccgagagggcctcctactcagaatccgaggtgaaggactacctgtggcagatgctg agcgccacacagtacctgcacaaccagcacatcctgcacctggacctgaggtccgagaac atgatcatcaccgaatacaacctgctcaaggtcgtggacctgggcaatgcacagagcctc agccaggagaaggtgctgccctcagagaagttcaaggactacctagagaccatggctcca gagctcctggagggccagggggctgttccacagacagacatctgggccatcggtgtgaca gccttcatcatgctgagcgccgagtacccggtgagcagcgagggtgcacgcgacctgcag agaggactgcgcaaggggctggtccggctgagccgctgctacgcggggctgtcggggggc gccgtggccttcctgcgcagcactctgtgcgcccagccctggggccggccctgcgcgtcc agctgcctgcagtgcccgtggctaacagaggagggcccggcctgttcgcggccagcgccc gtgaccttccctaccgcgcggctgcgcgtcttcgtgcgcaatcgcgagaagagacgcgcg ctgctgtacaagaggcacaacctggcccaggtgcgctga

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