Pan paniscus (bonobo): 100980644 Help Entry 100980644         CDS       T02283                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4 precursor   KO K10160   toll-like receptor 4 Organism pps  Pan paniscus (bonobo) Pathway pps04064   NF-kappa B signaling pathway pps04066   HIF-1 signaling pathway pps04145   Phagosome pps04151   PI3K-Akt signaling pathway pps04217   Necroptosis pps04613   Neutrophil extracellular trap formation pps04620   Toll-like receptor signaling pathway pps04621   NOD-like receptor signaling pathway pps04936   Alcoholic liver disease pps05132   Salmonella infection pps05133   Pertussis pps05134   Legionellosis pps05135   Yersinia infection pps05140   Leishmaniasis pps05142   Chagas disease pps05144   Malaria pps05145   Toxoplasmosis pps05146   Amoebiasis pps05152   Tuberculosis pps05161   Hepatitis B pps05162   Measles pps05164   Influenza A pps05170   Human immunodeficiency virus 1 infection pps05171   Coronavirus disease - COVID-19 pps05205   Proteoglycans in cancer pps05235   PD-L1 expression and PD-1 checkpoint pathway in cancer pps05321   Inflammatory bowel disease pps05323   Rheumatoid arthritis pps05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:pps00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     100980644 (TLR4)    04066 HIF-1 signaling pathway     100980644 (TLR4)    04151 PI3K-Akt signaling pathway     100980644 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     100980644 (TLR4)   09143 Cell growth and death    04217 Necroptosis     100980644 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     100980644 (TLR4)    04620 Toll-like receptor signaling pathway     100980644 (TLR4)    04621 NOD-like receptor signaling pathway     100980644 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     100980644 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100980644 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100980644 (TLR4)    05161 Hepatitis B     100980644 (TLR4)    05171 Coronavirus disease - COVID-19     100980644 (TLR4)    05164 Influenza A     100980644 (TLR4)    05162 Measles     100980644 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     100980644 (TLR4)    05135 Yersinia infection     100980644 (TLR4)    05133 Pertussis     100980644 (TLR4)    05134 Legionellosis     100980644 (TLR4)    05152 Tuberculosis     100980644 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     100980644 (TLR4)    05144 Malaria     100980644 (TLR4)    05145 Toxoplasmosis     100980644 (TLR4)    05140 Leishmaniasis     100980644 (TLR4)    05142 Chagas disease     100980644 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     100980644 (TLR4)    05321 Inflammatory bowel disease     100980644 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100980644 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     100980644 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pps04131]     100980644 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:pps04054]     100980644 (TLR4)    04090 CD molecules [BR:pps04090]     100980644 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:pps00536]     100980644 (TLR4) Membrane trafficking [BR:pps04131]  Endocytosis   Phagocytosis    Toll-like receptors     100980644 (TLR4) Pattern recognition receptors [BR:pps04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    100980644 (TLR4) CD molecules [BR:pps04090]  Proteins   100980644 (TLR4) Glycosaminoglycan binding proteins [BR:pps00536]  Hyaluronan   Cell surface receptors    100980644 (TLR4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  LRR_8 TIR LRR_4 LRR_1 TIR_2 LRR_9 LRR_Zer-1 LRR_6 LRR_EndoS ThsB_TIR LRR_R13L1-DRL21 Curto_V2 Motif Other DBs NCBI-GeneID:  100980644 NCBI-ProteinID:  NP_001266152 Ensembl:  ENSPPAG00000031203 UniProt:  B3Y628 LinkDB All DBs Position 11:complement(21637696..21650558) Genome browser AA seq 839 aa AA seqDB search MMSASRLAGTLIPAMAFLSCVRPESWEPCVEVVPNITYQCMELNFYKIPDNLPFSTKNLD LSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGNPIQSLALG AFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEHL DLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLHKLTLRNNFDSL NVMKTCIQGLAGLEVHRLVLGEFRNEENLEKFDKSALEGLCNLTIEEFRLAYLDYYLDDI IDLFNCLTNVSSFSLVSVTIKSVKDFSYNFGWQHLELVKCKFGQFPTLKLKSLKRLTFTS NKGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTTSLKYLDLSFNGVITMSSNFLG LEQLEHLDFQHSNLKQMSEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMAG NSFQENFLPDIFTELRNLTFLDLSQCQLEQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPY KCLNSLQVLDYSLNHIMTSKKQELQHFPSSLAFLNLTQNDFACTCEHQSFLQWIKDQRQL LVEVERMECATPSDKQGMPVLSLNITCQMNKTIIGVSVLSVLVVSVVAVLVYKFYFHLML LAGCIKYGRGENIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAA NIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLR RQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKSWNPEGTVGTGCNWQEATSI NT seq 2520 nt NT seq  +upstreamnt  +downstreamnt atgatgtctgcctcgcgcctggctgggactctgatcccagccatggccttcctctcctgc gtgagaccagaaagctgggagccctgcgtggaggtggttcctaatattacttatcaatgc atggagctgaatttctacaaaatccccgacaacctccccttctcaaccaagaacctggac ctgagctttaatcccctgaggcatttaggcagctatagcttcttcagtttcccagaactg caggtgctggatttatccaggtgtgaaatccagacaattgaagatggggcatatcagagc ctaagccacctctccaccttaatattgacaggaaaccccatccagagtttagccctggga gccttttctggactatcaagtttacagaagctggtggctgtggagacaaatctagcatct ctagagaacttccccattggacatctcaaaactttgaaagaacttaatgtggctcacaat cttatccaatctttcaaattacctgagtatttttctaatctgaccaatctagagcacttg gacctttccagcaacaagattcaaagtatttattgcacagacttgcgggttctacatcaa atgcccctactcaatctctctttagacctgtccctgaaccctatgaactttatccaacca ggtgcatttaaagaaattaggcttcataagctgactttgagaaataattttgatagttta aatgtaatgaaaacttgtattcaaggtctggctggtttagaagtccatcgtttggttctg ggagaatttagaaatgaagaaaacttggaaaagtttgacaaatctgctctagagggcctg tgcaatttgaccattgaagaattccgattagcatacttagactactacctcgatgatatt attgacttatttaattgtttgacaaatgtttcttcattttccctggtgagtgtgactatt aaaagcgtaaaagacttttcttataatttcggatggcaacatttagaattagttaagtgt aaatttggacagtttcccacattgaaactcaaatctctcaaaaggcttactttcacttcc aacaaaggtgggaatgctttttcagaagttgatctaccaagccttgagtttctagatctc agtagaaatggcttgagtttcaaaggttgctgttctcaaagtgattttgggacaaccagc ctaaagtatttagatctgagcttcaatggtgttattaccatgagttcaaacttcttgggc ttagaacaactagaacatctggatttccagcattccaatttgaaacaaatgagtgagttt tcagtattcctatcactcagaaacctcatttaccttgacatttctcatactcacaccaga gttgctttcaatggcatcttcaatggcttgtccagtctcgaagtcttgaaaatggctggc aattctttccaggaaaacttccttccagatatcttcacagagctgagaaacttgaccttc ctggacctctctcagtgtcaactggagcagttgtctccaacagcatttaactcactctcc agtcttcaggtactaaatatgagccacaacaacttcttttcattggatacgtttccttat aagtgtctgaactccctccaggttcttgattacagtctcaatcacataatgacttccaaa aaacaggaactacagcattttccaagtagtctagctttcttaaatcttactcagaatgac tttgcttgtacttgtgaacaccaaagtttcctgcaatggatcaaggaccagaggcagctc ttggtggaagttgaacgaatggaatgtgcaacaccttcagataagcagggcatgcctgtg ctgagtttgaatatcacctgtcagatgaataagaccatcattggtgtgtcggtcctcagt gtgcttgtagtatctgttgtagcagttctggtctataagttctattttcacctgatgctt cttgctggctgcataaagtatggtagaggtgaaaacatctatgatgcctttgttatctac tcaagccaggatgaggactgggtaaggaatgagctagtaaagaatttagaagaaggggtg cctccatttcagctctgccttcactacagagactttattcccggtgtggccattgctgcc aacatcatccatgaaggtttccataaaagccgaaaggtgattgttgtggtgtcccagcac ttcatccagagccgctggtgtatctttgaatatgagattgctcagacgtggcagtttctg agcagtcgtgctggtatcatcttcattgtcctgcagaaggtggagaagaccctgctcagg cggcaggtggagctgtaccgccttctcagcaggaacacttacctggagtgggaggacagt gtcctggggcggcacatcttctggagacgactcagaaaagccctgctggatggtaaatca tggaatccagaaggaacagtgggtacaggatgcaattggcaggaagcaacatctatctga

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