KEGG   Pan paniscus (bonobo): 100980937
Entry
100980937         CDS       T02283                                 
Symbol
MAPK11
Name
(RefSeq) mitogen-activated protein kinase 11 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01522  Endocrine resistance
pps04010  MAPK signaling pathway
pps04015  Rap1 signaling pathway
pps04068  FoxO signaling pathway
pps04071  Sphingolipid signaling pathway
pps04114  Oocyte meiosis
pps04148  Efferocytosis
pps04218  Cellular senescence
pps04261  Adrenergic signaling in cardiomyocytes
pps04370  VEGF signaling pathway
pps04380  Osteoclast differentiation
pps04517  IgSF CAM signaling
pps04519  Cadherin signaling
pps04550  Signaling pathways regulating pluripotency of stem cells
pps04611  Platelet activation
pps04613  Neutrophil extracellular trap formation
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04625  C-type lectin receptor signaling pathway
pps04657  IL-17 signaling pathway
pps04658  Th1 and Th2 cell differentiation
pps04659  Th17 cell differentiation
pps04660  T cell receptor signaling pathway
pps04664  Fc epsilon RI signaling pathway
pps04668  TNF signaling pathway
pps04670  Leukocyte transendothelial migration
pps04714  Thermogenesis
pps04722  Neurotrophin signaling pathway
pps04723  Retrograde endocannabinoid signaling
pps04728  Dopaminergic synapse
pps04750  Inflammatory mediator regulation of TRP channels
pps04912  GnRH signaling pathway
pps04914  Progesterone-mediated oocyte maturation
pps04917  Prolactin signaling pathway
pps04926  Relaxin signaling pathway
pps04932  Non-alcoholic fatty liver disease
pps04933  AGE-RAGE signaling pathway in diabetic complications
pps04935  Growth hormone synthesis, secretion and action
pps04936  Alcoholic liver disease
pps05014  Amyotrophic lateral sclerosis
pps05020  Prion disease
pps05022  Pathways of neurodegeneration - multiple diseases
pps05132  Salmonella infection
pps05133  Pertussis
pps05135  Yersinia infection
pps05140  Leishmaniasis
pps05142  Chagas disease
pps05145  Toxoplasmosis
pps05152  Tuberculosis
pps05161  Hepatitis B
pps05163  Human cytomegalovirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease
pps05205  Proteoglycans in cancer
pps05208  Chemical carcinogenesis - reactive oxygen species
pps05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pps05415  Diabetic cardiomyopathy
pps05417  Lipid and atherosclerosis
pps05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100980937 (MAPK11)
   04015 Rap1 signaling pathway
    100980937 (MAPK11)
   04370 VEGF signaling pathway
    100980937 (MAPK11)
   04668 TNF signaling pathway
    100980937 (MAPK11)
   04068 FoxO signaling pathway
    100980937 (MAPK11)
   04071 Sphingolipid signaling pathway
    100980937 (MAPK11)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    100980937 (MAPK11)
   04519 Cadherin signaling
    100980937 (MAPK11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100980937 (MAPK11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    100980937 (MAPK11)
   04218 Cellular senescence
    100980937 (MAPK11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100980937 (MAPK11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100980937 (MAPK11)
   04613 Neutrophil extracellular trap formation
    100980937 (MAPK11)
   04620 Toll-like receptor signaling pathway
    100980937 (MAPK11)
   04621 NOD-like receptor signaling pathway
    100980937 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    100980937 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    100980937 (MAPK11)
   04660 T cell receptor signaling pathway
    100980937 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    100980937 (MAPK11)
   04659 Th17 cell differentiation
    100980937 (MAPK11)
   04657 IL-17 signaling pathway
    100980937 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    100980937 (MAPK11)
   04670 Leukocyte transendothelial migration
    100980937 (MAPK11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100980937 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    100980937 (MAPK11)
   04917 Prolactin signaling pathway
    100980937 (MAPK11)
   04926 Relaxin signaling pathway
    100980937 (MAPK11)
   04935 Growth hormone synthesis, secretion and action
    100980937 (MAPK11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100980937 (MAPK11)
  09156 Nervous system
   04728 Dopaminergic synapse
    100980937 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    100980937 (MAPK11)
   04722 Neurotrophin signaling pathway
    100980937 (MAPK11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100980937 (MAPK11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100980937 (MAPK11)
  09159 Environmental adaptation
   04714 Thermogenesis
    100980937 (MAPK11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100980937 (MAPK11)
   05208 Chemical carcinogenesis - reactive oxygen species
    100980937 (MAPK11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100980937 (MAPK11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100980937 (MAPK11)
   05161 Hepatitis B
    100980937 (MAPK11)
   05171 Coronavirus disease
    100980937 (MAPK11)
   05163 Human cytomegalovirus infection
    100980937 (MAPK11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100980937 (MAPK11)
   05169 Epstein-Barr virus infection
    100980937 (MAPK11)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100980937 (MAPK11)
   05135 Yersinia infection
    100980937 (MAPK11)
   05133 Pertussis
    100980937 (MAPK11)
   05152 Tuberculosis
    100980937 (MAPK11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100980937 (MAPK11)
   05140 Leishmaniasis
    100980937 (MAPK11)
   05142 Chagas disease
    100980937 (MAPK11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100980937 (MAPK11)
   05020 Prion disease
    100980937 (MAPK11)
   05022 Pathways of neurodegeneration - multiple diseases
    100980937 (MAPK11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100980937 (MAPK11)
   05418 Fluid shear stress and atherosclerosis
    100980937 (MAPK11)
   05415 Diabetic cardiomyopathy
    100980937 (MAPK11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100980937 (MAPK11)
   04932 Non-alcoholic fatty liver disease
    100980937 (MAPK11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100980937 (MAPK11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100980937 (MAPK11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pps01001]
    100980937 (MAPK11)
Enzymes [BR:pps01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100980937 (MAPK11)
Protein kinases [BR:pps01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   100980937 (MAPK11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH RIO1 Cas_CT1975
Other DBs
NCBI-GeneID: 100980937
NCBI-ProteinID: XP_034805084
LinkDB
Position
23:complement(60169844..60176642)
AA seq 364 aa
MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
EIEQ
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgtcgggccctcgcgccggcttctaccggcaggagctgaacaagaccgtgtgggaggtg
ccgcagcggctgcaggggctgcgcccggtgggctccggcgcctacggctccgtctgttcg
gcctacgacgcccggctgcgccagaaggtggcggtgaagaagctgtcgcgccccttccag
tcgctgatccacgcgcgcagaacgtaccgggagctgcggctgctcaagcacctgaagcac
gagaacgtcatcgggcttctggacgtcttcacgccggccacgtccatcgaggacttcagc
gaagtgtacttggtgaccaccctgatgggcgccgacctgaacaacatcgtcaagtgccag
gcgctgagcgacgagcacgttcaattcctggtttaccagctgctgcgcgggctgaagtac
atccactcggccgggatcatccaccgggacctgaagcccagcaacgtggctgtgaacgag
gactgtgagctcaggatcctggatttcgggctggcacgccaggcggacgaggagatgacc
ggctatgtggccacacgctggtaccgggcacctgagatcatgctcaactggatgcattac
aaccaaacagtggatatctggtccgtgggctgcatcatggctgagctgctccagggcaag
gccctcttcccgggaagcgactacattgaccagctgaagcgcatcatggaagtggtgggc
acacccagccctgaggttctggcaaaaatctcctcggaacacgcccggacatatatccag
tccctgccccccatgccccagaaggacctgagcagcatcttccgtggagccaaccccctg
gccatagacctccttggaaggatgctggtgctggacagtgaccagagggtcagtgcggct
gaggcactggcccacgcctacttcagccagtaccacgaccccgaggatgagccagaggcc
gagccatatgatgagagcgttgaggccaaggagcgcacgctggaggagtggaaggagctc
acttaccaggaagtcctcagcttcaagcccccagagccaccgaagccacctggcagcctg
gagattgagcagtga

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