Pan paniscus (bonobo): 100981083
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Entry
100981083 CDS
T02283
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
pps
Pan paniscus (bonobo)
Pathway
pps01521
EGFR tyrosine kinase inhibitor resistance
pps01522
Endocrine resistance
pps04010
MAPK signaling pathway
pps04014
Ras signaling pathway
pps04015
Rap1 signaling pathway
pps04066
HIF-1 signaling pathway
pps04068
FoxO signaling pathway
pps04081
Hormone signaling
pps04114
Oocyte meiosis
pps04140
Autophagy - animal
pps04144
Endocytosis
pps04150
mTOR signaling pathway
pps04151
PI3K-Akt signaling pathway
pps04152
AMPK signaling pathway
pps04211
Longevity regulating pathway
pps04213
Longevity regulating pathway - multiple species
pps04510
Focal adhesion
pps04518
Integrin signaling
pps04519
Cadherin signaling
pps04520
Adherens junction
pps04550
Signaling pathways regulating pluripotency of stem cells
pps04730
Long-term depression
pps04913
Ovarian steroidogenesis
pps04914
Progesterone-mediated oocyte maturation
pps05200
Pathways in cancer
pps05202
Transcriptional misregulation in cancer
pps05205
Proteoglycans in cancer
pps05214
Glioma
pps05215
Prostate cancer
pps05218
Melanoma
pps05224
Breast cancer
pps05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
pps00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100981083 (IGF1R)
04014 Ras signaling pathway
100981083 (IGF1R)
04015 Rap1 signaling pathway
100981083 (IGF1R)
04066 HIF-1 signaling pathway
100981083 (IGF1R)
04068 FoxO signaling pathway
100981083 (IGF1R)
04151 PI3K-Akt signaling pathway
100981083 (IGF1R)
04152 AMPK signaling pathway
100981083 (IGF1R)
04150 mTOR signaling pathway
100981083 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
100981083 (IGF1R)
04518 Integrin signaling
100981083 (IGF1R)
04519 Cadherin signaling
100981083 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100981083 (IGF1R)
04140 Autophagy - animal
100981083 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
100981083 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100981083 (IGF1R)
04520 Adherens junction
100981083 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
100981083 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
100981083 (IGF1R)
04914 Progesterone-mediated oocyte maturation
100981083 (IGF1R)
09156 Nervous system
04730 Long-term depression
100981083 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
100981083 (IGF1R)
04213 Longevity regulating pathway - multiple species
100981083 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100981083 (IGF1R)
05202 Transcriptional misregulation in cancer
100981083 (IGF1R)
05205 Proteoglycans in cancer
100981083 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100981083 (IGF1R)
05214 Glioma
100981083 (IGF1R)
05218 Melanoma
100981083 (IGF1R)
05215 Prostate cancer
100981083 (IGF1R)
05224 Breast cancer
100981083 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100981083 (IGF1R)
01522 Endocrine resistance
100981083 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pps01001
]
100981083 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pps04090
]
100981083 (IGF1R)
Enzymes [BR:
pps01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100981083 (IGF1R)
Protein kinases [BR:
pps01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
100981083 (IGF1R)
CD molecules [BR:
pps04090
]
Proteins
100981083 (IGF1R)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Kinase-like
Motif
Other DBs
NCBI-GeneID:
100981083
NCBI-ProteinID:
XP_034795376
Ensembl:
ENSPPAG00000027660
LinkDB
All DBs
Position
16:88195825..88510506
Genome browser
AA seq
1364 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSTCGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRH
NYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
EPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKEEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASLPLPDRHSGH
KAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4095 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttctctcc
gccgcgctctcgctctggccgacgagtggagaaatctgcgggccaggcatcgacatccgc
aacgactatcagcagctgaagcgcctggagaactgcacggtgatcgagggctacctccac
atcctgctcatctccaaggccgaggactaccgcagctaccgcttccccaagctcacggtc
attaccgagtacttgctgctgttccgagtggctggcctcgagagcctcggagacctcttc
cccaacctcacggtcatccgcggctggaaactcttctacaactacgccctggtcatcttc
gagatgaccaatctcaaggatattgggctttacaacctgaggaacattactcggggggcc
atcaggattgagaaaaatgctgacctctgttacctctccactgtggactggtccctgatc
ctggatgcggtgtccaataactacattgtggggaataagcccccaaaggaatgtggggac
ctgtgtccagggaccatggaggagaagccgatgtgtgagaagaccaccatcaacaatgag
tacaactaccgctgctggaccacaaaccgctgccagaaaatgtgcccgagcacgtgtggg
aagcgggcgtgcaccgagaacaacgagtgctgccaccccgagtgcctgggcagctgcagc
gcgcctgacaacgacacggcctgtgtagcttgccgccactactactatgccggtgtctgt
gtgcctgcctgcccgcccaacacctacaggtttgagggctggcgctgtgtggaccgtgac
ttctgcgccaacatcctcagcgccgagagcagcgactccgaggggtttgtgatccacgac
ggcgagtgcatgcaggagtgcccctcgggcttcatccgcaacggcagccagagcatgtac
tgcatcccttgtgaaggtccttgcccgaaggtctgtgaggaagaaaagaaaacaaagacc
attgattctgttacttctgctcagatgctccaaggatgcaccatcttcaagggcaatttg
ctcattaacatccgacgggggaataacattgcttcagaactggagaacttcatggggctc
atcgaggtggtgacgggctacgtgaagatccgccattctcatgccttggtctccttgtcc
ttcctaaaaaaccttcgcctcatcttaggagaggagcagctagaagggaattactccttc
tacgtcctcgacaaccagaacttgcagcaactatgggactgggaccaccgcaacctgacc
atcaaagcagggaaaatgtactttgctttcaatcccaaattatgtgtttccgaaatttac
cgcatggaggaagtgacggggactaaagggcgccaaagcaaaggggacataaacaccagg
aacaacggggagagagcctcctgtgaaagtgacgtcctgcatttcacctccaccaccacg
tcgaagaatcgcatcatcataacctggcaccggtaccggccccctgactacagggatctc
atcagcttcaccgtttactacaaggaagcaccctttaagaatgtcacggagtatgatggg
caggacgcctgcggctccaacagctggaacatggtggacgtggacctcccgcccaacaag
gacgtggagcccggcatcttactacatgggctgaagccctggactcagtacgccgtttac
gtcaaggctgtgaccctcaccatggtggagaacgaccatatccgtggggccaagagtgag
atcttgtacattcgcaccaatgcttcagttccttccattcccttggacgttctttcagca
tcgaactcctcttctcagttaatcgtgaagtggaaccctccctctctgcccaacggcaac
ctgagttactacattgttcgctggcagcggcagcctcaggacggctacctttaccggcac
aattactgctccaaagacaaaatccccatcaggaagtatgccgacggcaccatcgacatt
gaggaggtcacagagaaccccaagactgaggtgtgtggtggggagaaagggccttgctgc
gcctgccccaaaactgaagccgagaagcaggccgagaaggaggaggctgaataccgcaaa
gtctttgagaatttcctgcacaactccatcttcgtgcccagacctgaaaggaagcggaga
gatgtcatgcaagtggccaacaccaccatgtccagccgaagcaggaacaccacggccgca
gacacctacaacatcaccgacccggaagagctggagacagagtaccctttctttgagagc
agagtggataacaaggagagaactgtgatttctaaccttcggcctttcacattgtaccgc
atcgatatccacagctgcaaccacgaggctgagaagctgggctgcagcgcctccaacttt
gtctttgcaaggactatgcccgcagaaggagcagatgacattcctgggccagtgacctgg
gagccaaggcctgaaaactccatctttttaaagtggccggaacctgagaatcccaatgga
ttgattctaatgtatgaaataaaatacggatcacaagttgaggatcagcgagaatgtgtg
tccagacaggaatacaggaagtatggaggggccaagctaaaccggctaaacccggggaac
tacacagcccggattcaggccacatctctctctgggaatgggtcgtggacagatcctgtg
ttcttctatgtccaggccaaaacaggatatgaaaacttcatccatctgatcatcgctctg
cccgtcgctgtcctgttgatcgtgggagggttggtgattatgctgtacgtcttccataga
aagagaaataacagcaggctggggaatggagtgctgtatgcctctgtgaacccggagtac
ttcagcgctgctgatgtgtacgttcccgatgagtgggaggtggctcgggagaagatcacc
atgagccgggaacttgggcaggggtcgtttgggatggtctatgaaggagttgccaagggt
gtggtgaaagatgaacctgaaaccagagtggccattaaaacagtgaacgaggccgcaagc
atgcgtgaaaggattgagtttctcaacgaagcttctgtgatgaaggagttcaattgtcac
catgtggtgcgattgctgggtgtggtgtcccaaggccagccaacactggtcatcatggaa
ctgatgacacggggcgatctcaaaagttatctccggtctctgaggccagaaatggagaat
aatccagtcctagcacctccaagcctgagcaagatgattcagatggccggagagattgca
gacggcatggcatacctcaacgccaataagttcgtccacagagaccttgctgcccggaat
tgcatggtagccgaagatttcacagtcaaaatcggagattttggtatgacgcgagatatc
tatgagacagactattaccggaaaggagggaaagggctgctgcccgtgcgctggatgtct
cccgagtccctcaaggatggagtcttcaccacttactcggacgtctggtccttcggggtc
gtcctctgggagatcgccacactggccgagcagccctaccagggcttgtccaacgagcaa
gtccttcgcttcgtcatggagggcggccttctggacaagccagacaactgtcctgacatg
ctgtttgaactgatgcgcatgtgctggcagtataaccccaagatgaggccttccttcctg
gagatcatcagcagcatcaaagaggagatggagcctggcttccgggaggtctccttctac
tacagcgaggagaacaagctgcccgagccggaggagctggacctggagccagagaacatg
gagagcgtccccctggacccctcggcctccctgccactgcccgacagacactcaggacac
aaggccgagaacggccccggccctggggtgctggtcctccgcgccagcttcgacgagaga
cagccgtacgcacacatgaacgggggccgcaagaacgagcgggccttgccgctgccccag
tcttcgacctgctga
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integrated database retrieval system
