Pan paniscus (bonobo): 100986423
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Entry
100986423 CDS
T02283
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
KO
K05704
tyrosine-protein kinase Src [EC:
2.7.10.2
]
Organism
pps
Pan paniscus (bonobo)
Pathway
pps01521
EGFR tyrosine kinase inhibitor resistance
pps01522
Endocrine resistance
pps04012
ErbB signaling pathway
pps04015
Rap1 signaling pathway
pps04062
Chemokine signaling pathway
pps04081
Hormone signaling
pps04137
Mitophagy - animal
pps04144
Endocytosis
pps04360
Axon guidance
pps04370
VEGF signaling pathway
pps04510
Focal adhesion
pps04517
IgSF CAM signaling
pps04518
Integrin signaling
pps04520
Adherens junction
pps04530
Tight junction
pps04540
Gap junction
pps04611
Platelet activation
pps04613
Neutrophil extracellular trap formation
pps04625
C-type lectin receptor signaling pathway
pps04727
GABAergic synapse
pps04750
Inflammatory mediator regulation of TRP channels
pps04810
Regulation of actin cytoskeleton
pps04912
GnRH signaling pathway
pps04915
Estrogen signaling pathway
pps04917
Prolactin signaling pathway
pps04919
Thyroid hormone signaling pathway
pps04921
Oxytocin signaling pathway
pps04926
Relaxin signaling pathway
pps05100
Bacterial invasion of epithelial cells
pps05135
Yersinia infection
pps05152
Tuberculosis
pps05161
Hepatitis B
pps05163
Human cytomegalovirus infection
pps05167
Kaposi sarcoma-associated herpesvirus infection
pps05168
Herpes simplex virus 1 infection
pps05203
Viral carcinogenesis
pps05205
Proteoglycans in cancer
pps05207
Chemical carcinogenesis - receptor activation
pps05208
Chemical carcinogenesis - reactive oxygen species
pps05219
Bladder cancer
pps05417
Lipid and atherosclerosis
pps05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pps00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100986423 (SRC)
04015 Rap1 signaling pathway
100986423 (SRC)
04370 VEGF signaling pathway
100986423 (SRC)
09133 Signaling molecules and interaction
04081 Hormone signaling
100986423 (SRC)
04517 IgSF CAM signaling
100986423 (SRC)
04518 Integrin signaling
100986423 (SRC)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100986423 (SRC)
04137 Mitophagy - animal
100986423 (SRC)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100986423 (SRC)
04520 Adherens junction
100986423 (SRC)
04530 Tight junction
100986423 (SRC)
04540 Gap junction
100986423 (SRC)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100986423 (SRC)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100986423 (SRC)
04613 Neutrophil extracellular trap formation
100986423 (SRC)
04625 C-type lectin receptor signaling pathway
100986423 (SRC)
04062 Chemokine signaling pathway
100986423 (SRC)
09152 Endocrine system
04912 GnRH signaling pathway
100986423 (SRC)
04915 Estrogen signaling pathway
100986423 (SRC)
04917 Prolactin signaling pathway
100986423 (SRC)
04921 Oxytocin signaling pathway
100986423 (SRC)
04926 Relaxin signaling pathway
100986423 (SRC)
04919 Thyroid hormone signaling pathway
100986423 (SRC)
09156 Nervous system
04727 GABAergic synapse
100986423 (SRC)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100986423 (SRC)
09158 Development and regeneration
04360 Axon guidance
100986423 (SRC)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100986423 (SRC)
05207 Chemical carcinogenesis - receptor activation
100986423 (SRC)
05208 Chemical carcinogenesis - reactive oxygen species
100986423 (SRC)
05203 Viral carcinogenesis
100986423 (SRC)
09162 Cancer: specific types
05219 Bladder cancer
100986423 (SRC)
09172 Infectious disease: viral
05161 Hepatitis B
100986423 (SRC)
05168 Herpes simplex virus 1 infection
100986423 (SRC)
05163 Human cytomegalovirus infection
100986423 (SRC)
05167 Kaposi sarcoma-associated herpesvirus infection
100986423 (SRC)
09171 Infectious disease: bacterial
05135 Yersinia infection
100986423 (SRC)
05152 Tuberculosis
100986423 (SRC)
05100 Bacterial invasion of epithelial cells
100986423 (SRC)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100986423 (SRC)
05418 Fluid shear stress and atherosclerosis
100986423 (SRC)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100986423 (SRC)
01522 Endocrine resistance
100986423 (SRC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pps01001
]
100986423 (SRC)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pps04131
]
100986423 (SRC)
Enzymes [BR:
pps01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100986423 (SRC)
Protein kinases [BR:
pps01001
]
Non-receptor tyrosine kinases
SRC family
100986423 (SRC)
Membrane trafficking [BR:
pps04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
100986423 (SRC)
Endocytosis
Clathrin-mediated endocytosis
Kinases
100986423 (SRC)
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
100986423 (SRC)
Macropinocytosis
Kinases
100986423 (SRC)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_9
SH3_2
SH2_1
ABC1
Haspin_kinase
DUF7063
DUF8712
Motif
Other DBs
NCBI-GeneID:
100986423
NCBI-ProteinID:
XP_034802834
Ensembl:
ENSPPAG00000040681
LinkDB
All DBs
Position
21:43073049..43132588
Genome browser
AA seq
553 aa
AA seq
DB search
MGSNKSKPKDASQRRRSLEPAENVHGAGGGAFPASQTPSKPASADGHRGPSAAFAPAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVSQTWFTFRWLQREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESER
LLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQF
NSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGE
VWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY
MSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVC
KVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR
VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYF
TSTEPQYQPGENL
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
atgggtagcaacaagagcaagcccaaggatgccagccagcggcgccgcagcctggagccc
gccgagaacgtgcacggcgctggcgggggcgctttccccgcctcgcagacccccagcaag
ccagcctcggccgacggccaccgcggccccagcgcggccttcgcccccgcggccgccgag
cccaagctgttcggaggcttcaactcctcggacaccgtcacctccccgcagagggcgggc
ccgctggccggtggagtgaccacctttgtggccctctatgactatgagtctaggacggag
acagacctgtccttcaagaaaggcgagcggctccagattgtcaacaacacgaggaaggtg
gatgtcagccagacctggttcacattcagatggctgcaaagagagggagactggtggctg
gcccactcgctcagcacaggacagacaggctacatccccagcaactacgtggcgccctcc
gactccatccaggccgaggagtggtattttggcaagatcaccagacgggagtcagagcgg
ttactgctcaatgcagagaacccgagagggaccttcctcgtgcgagaaagtgagaccacg
aaaggtgcctactgcctctcagtgtctgacttcgacaacgccaagggcctcaatgtgaag
cactacaagatccgcaagctggacagcggtggcttctacatcacctcccgcacccagttc
aacagcctgcagcagctggtggcctactactccaaacacgccgatggcctgtgccaccgc
ctcaccaccgtgtgccccacgtccaagccgcagactcagggcctggccaaggatgcctgg
gagatccctcgggagtcgctgcggctggaggtcaagctgggccagggctgctttggcgag
gtgtggatggggacctggaacggtaccaccagggtggccatcaaaaccctgaagcctggc
acgatgtctccagaggccttcctgcaggaggcccaggtcatgaagaagctgaggcatgag
aagctggtgcagttgtatgctgtggtttcagaggagcccatttacatcgtcacggagtac
atgagcaaggggagtttgctggactttctcaagggggagacaggcaagtacctgcggctg
cctcagctggtggacatggctgctcagatcgcctcaggcatggcgtacgtggagcggatg
aactacgtccaccgggaccttcgtgcagccaacatcctggtgggagagaacctggtgtgc
aaagtggccgactttgggctggctcggctcattgaagacaatgagtacacggcgcggcaa
ggtgccaaattccccatcaagtggacggctccagaagctgccctctatggccgcttcacc
atcaagtcagacgtgtggtccttcgggatcctgctgactgagctcaccacaaagggacgg
gtgccctaccctgggatggtgaaccgcgaggtgctggaccaggtggagcggggctaccgg
atgccctgcccgccggagtgtcccgagtccctgcacgacctcatgtgccagtgctggcgg
aaggagcctgaggagcggcccaccttcgagtacctgcaggccttcctggaggactacttc
acgtccaccgagccccagtaccagcccggggagaacctctag
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