Pan paniscus (bonobo): 100989182
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Entry
100989182 CDS
T02283
Symbol
CYP17A1
Name
(RefSeq) steroid 17-alpha-hydroxylase/17,20 lyase
KO
K00512
steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:
1.14.14.19
1.14.14.32
]
Organism
pps
Pan paniscus (bonobo)
Pathway
pps00140
Steroid hormone biosynthesis
pps01100
Metabolic pathways
pps04913
Ovarian steroidogenesis
pps04917
Prolactin signaling pathway
pps04927
Cortisol synthesis and secretion
pps04934
Cushing syndrome
Module
pps_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
pps_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
pps_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
pps_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pps00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100989182 (CYP17A1)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
100989182 (CYP17A1)
04917 Prolactin signaling pathway
100989182 (CYP17A1)
04927 Cortisol synthesis and secretion
100989182 (CYP17A1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100989182 (CYP17A1)
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:
pps00199
]
100989182 (CYP17A1)
Enzymes [BR:
pps01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.19 steroid 17alpha-monooxygenase
100989182 (CYP17A1)
1.14.14.32 17alpha-hydroxyprogesterone deacetylase
100989182 (CYP17A1)
Cytochrome P450 [BR:
pps00199
]
Cytochrome P450, animal type
CYP17 family
100989182 (CYP17A1)
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
p450
Motif
Other DBs
NCBI-GeneID:
100989182
NCBI-ProteinID:
XP_034787281
VGNC:
83048
LinkDB
All DBs
Position
8:complement(114715581..114722944)
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AA seq
508 aa
AA seq
DB search
MWELVALLLLTLAYLFWPKRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKY
GPIYSVRMGTKTIVIVGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRKGIAFADSGAH
WQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVIS
LICFNTSYKNGDPELNIIQNYNEGIIDNLSKDSLVDLVPWLKIFPNKTLEKLKSHVKIRN
DLLNKILENYKEKFRSDSITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIF
GAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREV
LRLRPVAPMLIPHKANVDSSIGEFAVDKGTQVIINLWALHHNEKEWHQPDQFMPERFLNP
AGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGIP
KVVFLIDSFKVKIKVRQAWREAQAEGST
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atgtgggagctcgtggctctcttgctgcttacactagcttatttgttttggcccaagaga
aggtgccctggtgccaagtaccccaagagcctcctgtccctgcccctggtgggcagcctg
ccattcctccccagacatggccatatgcataacaacttcttcaagctgcagaaaaaatat
ggccccatctattccgttcgtatgggcaccaagactatagtgattgtcggccaccaccag
ctggccaaggaggtgcttattaagaagggcaaggacttctctgggcggcctcaaatggca
actctagacatcgcgtccaacaaccgtaagggtatcgccttcgctgactctggtgcacac
tggcagctgcatcgaaggctggcaatggccacctttgccctgttcaaggacggcgatcag
aagctggagaagatcatttgtcaggaaatcagtacattgtgtgatatgctggccacccac
aacggacagtccatagacatctcctttcctgtcttcgtggcggtaaccaatgtcatctcc
ttgatctgcttcaatacctcctacaagaatggggaccctgagttgaatattatacagaat
tacaatgaaggcatcatagacaacctgagcaaagacagcctggtggacctagtcccctgg
ttgaagattttccccaacaaaaccctggaaaaattaaagagccatgttaaaatacgaaat
gatctgctgaataaaatacttgaaaattacaaggagaaattccggagtgactctatcacc
aacatgctggacacactgatgcaagccaagatgaactcagataatggcaatgctggccca
gatcaagactcagagctgctttcagataaccacattctcaccaccataggggacatcttt
ggggctggcgtggagaccaccacctctgtggttaaatggaccctggccttcctgctgcac
aatcctcaggtgaagaagaagctctacgaggagattgaccagaatgtgggtttcagccgc
acaccaactatcagtgaccgtaaccgtctcctcctgctggaggccaccatccgagaggtg
cttcgcctcaggcccgtggcccctatgctcattccccacaaggccaacgttgactccagc
atcggtgagtttgctgtggacaagggcacacaagttatcatcaatctgtgggcgctgcat
cacaatgagaaggagtggcaccagccggatcagttcatgcctgagcgtttcttgaatcca
gcggggacccagctcatctcaccgtcagtaagctatttgcccttcggagcaggtcctcgc
tcctgtataggtgagatcctggcccgccaggagctcttcctcatcatggcctggctgctg
cagaggttcgacctggaggtgccagatgatggacagctgccctccctggaaggcatcccc
aaggtggtctttctgatcgactctttcaaagtgaagatcaaggtgcgccaggcctggagg
gaagcccaggctgagggtagcacctaa
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