Pan paniscus (bonobo): 100990530
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Entry
100990530 CDS
T02283
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
pps
Pan paniscus (bonobo)
Pathway
pps00790
Folate biosynthesis
pps01100
Metabolic pathways
pps01240
Biosynthesis of cofactors
pps01523
Antifolate resistance
pps04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
pps00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
100990530 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
100990530 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100990530 (FPGS)
Enzymes [BR:
pps01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
100990530 (FPGS)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
100990530
NCBI-ProteinID:
XP_034785005
Ensembl:
ENSPPAG00000042999
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All DBs
Position
11:complement(11541063..11552677)
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AA seq
587 aa
AA seq
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MSRARSHLRAALFLAAASARGVTTQVAARRGLSAWPVPQEPSMEYQDAVRMLNTLQTNAG
YLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGSCVSMPPYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA
WQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPMLEALEEGGPPLTLGLEGE
HQRSNAALALQLAHCWLQRQDRHGAGEPKASRPGLLWQLPLAPVFQPTSHMRLGLRNTEW
PGRTQVLRRGPLTWYLDGAHTASSVQACVRWFRQALQGRERPSGGPEVRVLLFNATGDRD
PAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQQHWNHLDEE
QASPDLWSAPSPEPGGSTSLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSP
PKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ
NT seq
1764 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcgcggagccacctgcgcgccgctctattcctggcagcagcgtctgcgcgc
ggcgtaacgacccaggtcgcggcgcggcggggcttgagcgcgtggccggtgccgcaggag
cccagcatggagtaccaggatgccgtgcgaatgctcaataccctgcagaccaatgccggc
tacctggagcaggtgaagcgccagcggggtgaccctcagacacagctggaagccatggaa
ctgtacctagcacggagtgggctgcaggtggaggacttggaccggctgaacatcatccac
gtcactgggacgaaggggaagggctccacctgtgccttcacggaatgtatcctccgaagc
tatggcctgaagacgggattctttagctctccccacctggtgcaggttcgggagcggatc
cgcatcaatgggcagcccatcagtcctgagctcttcaccaagtacttctggcgcctctac
caccggctggaggagaccaaggatggcagctgtgtctccatgcccccctacttccgcttc
ctgacactcatggccttccacgtcttcctccaagagaaggtggacctggcagtggtggag
gtgggcattggcggggcttatgactgcaccaacatcatcaggaagcctgtggtgtgtgga
gtctcctctcttggcatcgaccacaccagcctcctgggggatacggtggagaagatcgca
tggcagaaagggggcatctttaagcaaggtgtccctgccttcactgtgctccaacctgaa
ggtcccctggcagtgctgagggaccgagcccagcagatctcatgtcctctatacctgtgt
ccgatgctggaggccctcgaggaaggggggccgccgctgaccctgggcctggagggggag
catcagcggtccaacgccgccttggccttgcagctggcccactgctggctgcagcggcag
gaccgccatggtgctggggagccaaaggcatccaggccagggctcctgtggcagctgccc
ctggcacccgtgttccagcccacatcccacatgcggctcgggcttcggaacacggagtgg
ccgggccggacgcaggtgctgcggcgcgggcccctcacctggtacctggacggtgcgcac
acggccagcagcgtgcaggcctgcgtgcgctggttccgccaggcgctgcagggccgcgag
aggccgagcggtggccccgaggttcgagtcttgctcttcaatgctaccggggaccgggac
ccggcggccctgctgaagctgctgcagccctgccagtttgactatgccgtcttctgccct
aacctgacagaggtgtcatccacaggcaacgcagaccaacagaacttcacagtgacactg
gaccaggttctgctccgctgcctggaacaccagcagcactggaaccacctggatgaagag
caggccagcccggacctctggagtgcccccagcccagagcccggtgggtccacatccctg
cttctggcgccccacccaccccacacctgcagtgccagctccctcgtcttcagctgcatt
tcacatgccttgcaatggatcagccaaggccgagaccccatcttccagccacctagtccc
ccaaagggcctcctcacccaccctgtggctcacagtggggccagcatactccgtgaggct
gctgccatccatgtgctagtcactggcagcctgcacctggtgggtggtgtcctgaagctg
ctggagcctgcactgtcccagtag
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