| Entry |
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| Symbol |
GAB1
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| Name |
(RefSeq) GRB2-associated-binding protein 1 isoform X2
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| KO |
| K09593 | GRB2-associated-binding protein 1 |
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| Organism |
pps Pan paniscus (bonobo)
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| Pathway |
| pps01521 | EGFR tyrosine kinase inhibitor resistance |
| pps04072 | Phospholipase D signaling pathway |
| pps05100 | Bacterial invasion of epithelial cells |
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| Brite |
KEGG Orthology (KO) [BR:pps00001]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100990740 (GAB1)
04014 Ras signaling pathway
100990740 (GAB1)
04072 Phospholipase D signaling pathway
100990740 (GAB1)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
100990740 (GAB1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100990740 (GAB1)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100990740 (GAB1)
05226 Gastric cancer
100990740 (GAB1)
05211 Renal cell carcinoma
100990740 (GAB1)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
100990740 (GAB1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100990740 (GAB1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04990 Domain-containing proteins not elsewhere classified [BR:pps04990]
100990740 (GAB1)
Domain-containing proteins not elsewhere classified [BR:pps04990]
Pleckstrin homology (PH) domain-containing proteins
Grb-2 associated binder (Gab) family proteins
100990740 (GAB1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
3:141213273..141349862
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| AA seq |
694 aa
MSGGEVVCSGWLRKSPPEKKLKRYAWKRRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRII
DLNLCQQVDAGLTFNKKEFENSYIFDINTIDRIFYLVADSEEEMNKWVRCICDICGFNPT
EEDPVKPPGSSLQAPADLPLAINTAPPSTQADSSSATLPPPYQLLNVPPHLETLGIQEDP
QDYLLLINCQSKKPEPTRTHADSAKSTSSETDCNDNVPSHKNPASSQSKHGMNGFFQQQM
MYDSPPSRALSASVDSSLYNLPRSYSHDVLPKVSPSSTEADGELYVFNTPSGTSSVETQM
RHVSISYDIPPTPGNTYQIPRTFPEGTLGQTSKLDTIPDIPPPRPPKPHPAHDRSPVETC
SIPRTASDTDSSYCIPTAGMSPSRSNTISTVDLNKLRKDASSQDCYDIPRTFPSDRSSSL
EGFHNHFKVKNVLTVGSVSSEELDENYVPMNPNSPPRQHSSSFTEPIQEANYVPMTPGTF
DFSSFGMQVPPPAHMGFRSSPKTPPRRPVPVADCEPPPVDRNLKPDRKVKPAPLEIKPLP
EWEELQAPVRSPITRSFARDSSRFPMSPRPDSVHSTTSSSDSHDSEENYVPMNPNLSSED
PNLFGSNSLDGGSSPMIKPKGDKQVEYLDLDLDSGKSTPPRKQKSSGSGSSVADERVDYV
VVDQQKTLALKSTREAWTDGRQSTESETPAKSVK |
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| NT seq |
2085 nt +upstreamnt +downstreamnt
atgagcggtggtgaagtggtctgctccggatggctccgcaagtcccccccggagaaaaag
ttgaagcgttatgcatggaagaggagatggttcgtgttacgcagtggccgtttaactgga
gatccagatgttttggaatattacaaaaatgatcatgccaagaagcctattcgtattatt
gatttaaatttatgtcaacaagtagatgcaggattgacatttaacaaaaaagagtttgaa
aacagctacatttttgatatcaacactattgaccggattttctacttggtagcagacagc
gaggaggagatgaataagtgggttcgttgtatttgtgacatctgtgggtttaatccaaca
gaagaagatcctgtgaagccacctggcagctctttacaagcaccagctgatttaccttta
gctataaatacagcaccaccatccacccaggcagattcatcctctgctactctacctcct
ccgtatcagctactcaatgttccaccacacctggaaactcttggcattcaggaggatcct
caagactacctgttgctcatcaactgtcaaagcaagaagcccgaacccaccagaacgcat
gctgattctgcaaaatccacctcttctgaaacagactgcaatgataacgtcccttctcat
aaaaatcctgcttcctcccagagcaaacatggaatgaatggcttttttcagcagcaaatg
atgtacgactctccaccttcacgtgccctatctgcttcagttgactccagcctttataac
ctgcccaggagttattcccatgatgttttaccaaaggtgtctccatcaagtactgaagca
gatggagaactctatgtttttaataccccatctgggacatcgagtgtagagactcaaatg
aggcatgtatctattagttatgacattcctccaacacctggtaatacttatcagattcca
cgaacatttccagaaggaaccttgggacagacatcaaagctagacactattccagatatt
cctccacctcggccaccgaaaccacatccagctcatgaccgatctcctgtggaaacgtgt
agtatcccacgcaccgcctcagacactgacagtagttactgtatccctacagcagggatg
tcgccttcacgtagtaataccatttccactgtggatttaaacaaattgcgaaaagatgct
agttctcaagactgctatgatattccacgaacatttccaagtgatagatctagttcactt
gaaggcttccataaccactttaaagtcaaaaatgtgttgacagtgggaagtgtttcaagt
gaagaactggatgaaaattacgtcccaatgaatcccaattcaccaccacgacaacattcc
agcagttttacagaaccaattcaggaagcaaattatgtgccaatgactccaggaacattt
gatttttcctcatttggaatgcaagttcctcctcctgctcatatgggcttcaggtccagc
ccaaaaacccctcccagaaggccagttcctgttgcagactgtgaaccaccccctgtggat
agaaacctcaagccagacagaaaagtcaagccagcacctttagaaataaaacctttgcca
gaatgggaagaattacaagccccagttagatctcccatcactaggagttttgctcgagac
tcttccaggtttcccatgtccccccgaccagattcagtgcatagcacaacttcaagcagt
gactcacacgacagtgaagagaattatgttcccatgaacccaaacctgtccagtgaagac
ccaaatctctttggcagtaacagtcttgatggaggaagcagccctatgatcaagcccaaa
ggagacaaacaggtggaatacttagatctcgacttagattctgggaaatccacaccacca
cgtaagcaaaagagcagtggctcaggcagcagtgtagcagatgagagagtggattatgtt
gttgttgaccaacagaagaccttggctctaaagagtacccgggaagcctggacagatggg
agacagtccacagaatcagaaacgccagcgaagagtgtgaaatga |
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