Pan paniscus (bonobo): 100992229
Help
Entry
100992229 CDS
T02283
Symbol
NOTCH2
Name
(RefSeq) neurogenic locus notch homolog protein 2 isoform X1
KO
K20994
Notch 2
Organism
pps
Pan paniscus (bonobo)
Pathway
pps01522
Endocrine resistance
pps04330
Notch signaling pathway
pps04658
Th1 and Th2 cell differentiation
pps04919
Thyroid hormone signaling pathway
pps05165
Human papillomavirus infection
pps05200
Pathways in cancer
pps05206
MicroRNAs in cancer
pps05207
Chemical carcinogenesis - receptor activation
pps05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
pps00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
100992229 (NOTCH2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
100992229 (NOTCH2)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100992229 (NOTCH2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100992229 (NOTCH2)
05206 MicroRNAs in cancer
100992229 (NOTCH2)
05207 Chemical carcinogenesis - receptor activation
100992229 (NOTCH2)
09162 Cancer: specific types
05224 Breast cancer
100992229 (NOTCH2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
100992229 (NOTCH2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
100992229 (NOTCH2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
EGF
hEGF
EGF_TEN
EGF_CA
Ank_2
EGF_2
Ank
NOD
Notch
NODP
Ank_5
Ank_3
Ank_4
EGF_3
JAG1-like_EGF2
EGF_Teneurin
Elf-1_N
Motif
Other DBs
NCBI-GeneID:
100992229
NCBI-ProteinID:
XP_054958508
Ensembl:
ENSPPAG00000030139
LinkDB
All DBs
Position
1:complement(112490679..112716322)
Genome browser
AA seq
2610 aa
AA seq
DB search
MRTGPVTRSRSLRAELGPALLPAGNPWVPKAAGPRPRRQWGGACGGRRRLRRKDTRGCFA
AHPRKFQPNFGRRLRRRPRSGGLGARGVQAFAPGLRSVAPGPEPLKQEEGRREWGSSIGT
PSPCGSAQAAVAAEEATEKMPALRPALLWALLALWLCCAAPAHALQCRDGYEPCVNEGMC
VTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKAMCRCASGFTGEDC
QYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTT
VANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSL
YVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNT
YNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDD
CAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYIC
TCPQGYKGADCTEDVDECSMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECH
SDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCP
PGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHH
GQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVN
CEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGV
NGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNEC
LSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHC
VLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKP
CMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCVDGVNTFSCLCLPGF
TGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGT
CVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQ
TLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQ
HSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQG
VNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQC
MDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHC
ETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPLGFSGARCQSSCGQVKCRKGEQCVHTA
SGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTP
PATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCD
ELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQPEN
LAEGTLVIVVLMPPEQLLQDARSFLRALGTLLHTNLRIKRDSQGELMVYPYYGEKSAAMK
KQRMTRRSLPGEQEQEVAGSKVFLEIDNRQCVQDSDHCFKNTDAAAALLASHAIQGTLSY
PLVSVVSESLTPERTQLLYLLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDA
SNHKRREPVGQDAVGLKNLSVQVSEANLIGSGTSEHWVDDEGPQPKKVKAEDEALLSEED
DPIDRRPWTQQHLEAADIRRTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGS
SDLSDEDEDAEDSSANIITDLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGA
DANAQDNMGRCPLHAAVAADAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVA
ELINCQADVNAVDDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREG
SYEAAKILLDHFANRDITDHMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALS
PVICGPNRSFLSLKHTPMGKKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQL
SESSVTLSPVDSLESPHTYVSDTTSSPMITSPGILQASPNPMLATAAPPAPVHAQHALSF
SNLHEMQPLAHGASTVLPSVSQLLSHHHIVSPGSGSAGSLSRLHPVPVPADWMNRMEVNE
TQYNEMFGMVLAPAEGTHPGIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGSIAQPAGA
PQPQSTCPPAVAGPLPTMYQIPEMARLPSVAFPTAMMPQQDGQVAQTILPAYHPFPASVG
KYPTPPSQHSYASSNAAERTPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTT
SPTPGGAGGGQRGPGTHMSEPPHNNMQVYA
NT seq
7833 nt
NT seq
+upstream
nt +downstream
nt
atgcggacggggccagtgactcgtagtagatccctccgcgcggagctcgggccggcgctt
cttcctgcgggaaacccctgggtgcccaaggcggcggggccgaggccgcggcgacagtgg
ggcggggcttgcggtgggaggaggcggctgaggcggaaggacacacgaggctgcttcgct
gcacacccgagaaagtttcagccaaacttcgggcggcggctgaggcggcggccgaggagc
ggcggactcggggcccggggagtccaggcatttgcgcctgggcttcggagcgtagcgcca
gggcctgagcctttgaagcaggaggaggggaggagagagtggggctcctctatcgggacc
ccttccccatgtggatctgcccaggcggcggtggcggcggaggaggcgaccgagaagatg
cccgccctgcgccccgctctgctgtgggcgctgctggcgctctggctgtgctgcgcggcc
cccgcgcatgcattgcagtgtcgagatggctatgaaccctgtgtaaatgaaggaatgtgt
gttacctaccacaatggcacaggatactgcaaatgtccagaaggcttcttgggggaatat
tgtcaacatcgagacccctgtgagaagaaccgctgccagaatggtgggacttgtgtggcc
caggccatgctggggaaagccatgtgccgatgtgcctcagggtttacaggagaggactgc
cagtactcgacatctcatccatgctttgtgtctcgaccctgcctgaatggcggcacatgc
catatgctcagccgggatacctatgagtgcacctgtcaagtcgggtttacaggtaaggag
tgccaatggaccgatgcctgcctgtctcatccctgtgcaaatggaagtacctgtaccact
gtggccaaccagttctcctgcaaatgcctcacaggcttcacagggcagaagtgtgagact
gatgtcaatgagtgtgacattccaggacactgccagcatggtggcacctgcctcaacctg
cctggttcctaccagtgccagtgccctcagggcttcacaggccagtactgtgacagcctg
tatgtgccctgtgcaccctcgccttgtgtcaatggaggcacctgtcggcagactggtgac
ttcacttttgagtgcaactgccttccaggttttgaagggagcacctgtgagaggaatatt
gatgactgccctaaccacaggtgtcagaatggaggggtttgtgtggatggggtcaacact
tacaactgccgctgtcccccacaatggacaggacagttctgcacagaggatgtggatgaa
tgcctgctgcagcccaatgcctgtcaaaatgggggcacctgtgccaaccgcaatggaggc
tatggctgtgtatgtgtcaacggctggagtggagatgactgcagtgagaacattgatgat
tgtgccttcgcctcctgtactccaggctccacctgcatcgaccgtgtggcctccttctct
tgcatgtgcccagaggggaaggcaggtctcctgtgtcatctggatgatgcatgcatcagc
aatccttgccacaagggggcactgtgtgacaccaaccccctaaatgggcaatatatttgc
acctgcccacaaggctacaaaggggctgactgcacagaagatgtggatgaatgttccatg
gccaatagcaatccttgtgagcatgcaggaaaatgtgtcaacacggatggcgccttccac
tgtgagtgtctgaagggttatgcaggacctcgttgtgagatggacatcaatgagtgccat
tcagacccctgccagaatgatgctacctgtctggataagattggaggcttcacatgtctg
tgcatgccaggtttcaaaggtgtgcattgtgaattagaaataaatgaatgtcagagcaac
ccttgtgtgaacaatgggcagtgtgtggataaagtcaatcgtttccagtgcctgtgtcct
cctggtttcactgggccagtttgccagattgatattgatgactgttccagtactccgtgt
ctgaatggggcaaagtgtatcgatcacccgaatggctatgaatgccagtgtgccacaggt
ttcactggtgtgttgtgtgaggagaacattgacaactgtgaccccgatccttgccaccat
ggtcagtgtcaggatggtattgattcctacacctgcatctgcaatcccgggtacatgggc
gccatctgcagtgaccagattgatgaatgttacagcagcccttgcctgaacgatggtcgc
tgcattgacctggtcaatggctaccagtgcaactgccagccgggcacgtcaggggttaat
tgtgaaattaattttgatgactgtgcaagtaacccttgtatccatggaatctgtatggat
ggcattaatcgctacagttgtgtctgctcaccaggattcacagggcagagatgtaacatt
gacattgatgagtgtgcctccaatccctgtcgcaagggtgcaacatgtatcaacggtgtg
aatggtttccgctgtatatgccccgagggaccccatcaccccagctgctactcacaggtg
aacgaatgcctgagcaatccctgcatccatggaaactgtactggaggtctcagtggatat
aagtgtctctgtgatgcaggctgggttggcatcaactgtgaagtggacaaaaatgaatgc
ctttcgaatccatgccagaatggaggaacttgtgacaatctggtgaatggatacaggtgt
acttgcaagaagggctttaaaggctataactgccaggtgaatattgatgaatgtgcctca
aatccatgcctgaaccaaggaacctgctttgatgacataagtggctacacttgccactgt
gtgctgccatacacaggcaagaattgtcagacagtattggctccctgttccccaaaccct
tgtgagaatgctgctgtttgcaaagagtcaccaaattttgagagttatacttgcttgtgt
gctcctggctggcaaggtcagcggtgtaccattgacattgacgagtgtatctccaagccc
tgcatgaaccatggtctctgccataacacccagggcagctacatgtgtgaatgtccacca
ggcttcagtggtatggactgtgaggaggacattgatgactgccttgccaatccttgccag
aatggaggttcctgtgtggatggagtgaatactttctcctgcctctgccttccgggtttc
actggggataagtgccagacagacatgaatgagtgtctgagtgaaccctgtaagaatgga
gggacctgctctgactacgtcaacagttacacttgcaagtgccaggcaggatttgatgga
gtccattgtgagaacaacatcaatgagtgcactgagagctcctgtttcaatggtggcaca
tgtgttgatgggattaactccttctcttgcttgtgccctgtgggtttcactggatccttc
tgcctccatgagatcaatgaatgcagctctcatccatgcctcaatgagggaacgtgtgtt
gatggcctgggtacctaccgctgcagctgccccctgggctacactgggaaaaactgtcag
accctggtgaacctctgcagtcggtctccatgtaaaaacaaaggtacttgcgttcagaaa
aaagcagagtcccagtgcctatgtccatctggatgggctggtgcctattgtgacgtgccc
aatgtctcttgtgacatagcagcctccaggagaggtgtgcttgttgaacacttgtgccag
cactcaggtgtctgcatcaatgctggcaacacgcattactgtcagtgccccctgggctat
actgggagctactgtgaggagcaactcgatgagtgtgcgtccaacccctgccagcacggg
gcaacatgcagtgacttcattggtggatacagatgcgagtgtgtcccaggctatcagggt
gtcaactgtgagtatgaagtggatgagtgccagaatcagccctgccagaatggaggcacc
tgtattgaccttgtgaaccatttcaagtgctcttgcccaccaggcactcggggcctactc
tgtgaagagaacattgatgactgtgcccggggtccccattgccttaatggtggtcagtgc
atggataggattggaggctacagttgtcgctgcttgcctggctttgctggggagcgttgt
gagggagacatcaacgagtgcctctccaacccctgcagctctgagggcagcctggactgt
atacagctcaccaatgactacctgtgtgtttgccgtagtgcctttactggccggcactgt
gaaaccttcgtcgatgtgtgtccccagatgccctgcctgaatggagggacttgtgctgtg
gccagtaacatgcctgatggtttcatttgccgttgtcccctgggattttctggggcaagg
tgccagagcagctgtggacaagtgaaatgtaggaaaggggagcagtgtgtgcacaccgcc
tctggaccccgctgcttctgccccagtccccgggactgcgagtcaggctgtgccagtagc
ccctgccagcacgggggcagctgccaccctcagcgccagcctccttattactcctgccag
tgtgccccaccattctcgggtagccgctgtgaactctacacggcaccccccagcacccct
cctgccacctgtctgagccagtattgtgccgacaaagctcgggatggcgtctgtgatgag
gcctgcaacagccatgcctgccagtgggatgggggtgactgttctctcaccatggagaac
ccctgggccaactgctcctccccacttccctgctgggattatatcaacaaccagtgtgat
gagctgtgcaacacggtcgagtgcctgtttgacaactttgaatgccaggggaacagcaag
acatgcaagtatgacaaatactgtgcagaccacttcaaagacaaccactgtgaccagggg
tgcaacagtgaggagtgtggttgggatgggctggactgtgctgctgaccaacctgagaac
ctggcagaaggtaccctggttattgtggtattgatgccacctgaacaactgctccaggat
gctcgcagcttcttgcgggcactgggtaccctgctccacaccaacctgcgcattaagcgg
gactcccagggggaactcatggtgtacccctattatggtgagaagtcagctgctatgaag
aaacagaggatgacacgcaggtcccttcctggtgaacaagaacaggaggtggctggctct
aaagtctttctggaaattgacaaccgccagtgtgttcaagactcagaccactgcttcaag
aacacggatgcagcagcagctctcctggcctctcacgccatacaggggaccctgtcatac
cctcttgtgtctgtcgtcagtgaatccctgactccagaacgcactcagctcctctatctc
cttgctgttgctgttgtcatcattctgtttattattctgctgggggtaatcatggcaaaa
cgaaagcgtaagcatggctctctctggctgcctgaaggtttcactcttcgccgagatgca
agcaatcacaagcgtcgtgagccagtgggacaggatgctgtggggctaaaaaatctctca
gtgcaagtctcagaagctaacctaattggttctggaacaagtgaacactgggtcgatgat
gaagggccccagccaaagaaagtaaaggctgaagatgaggccttactctcagaagaagat
gaccccattgatcgacggccatggacacagcagcaccttgaagccgcagacatccgtagg
acaccatcgctggctctcacccctcctcaggcagagcaggaggtggatgtgttagatgtg
aatgtccgtggcccagatggctgcaccccattgatgttggcttctctccgaggaggcagc
tcagatttgagtgatgaagatgaagatgcagaggactcttctgctaacatcatcacagac
ttggtctaccagggtgccagcctccaggcccagacagaccggactggtgagatggccctg
caccttgcagcccgctactcacgggctgatgctgccaagcgtctcctggatgcaggtgca
gatgccaatgcccaggacaacatgggccgctgcccactccatgctgcagtggcagctgat
gcccaaggtgtcttccagattctgattcgcaaccgagtaactgatctagatgccaggatg
aatgatggtactacacccctgatcctggctgcccgcctggctgtggagggaatggtggca
gaactgatcaactgccaagcggatgtgaatgcagtggatgaccatggaaaatctgctctt
cactgggcagctgctgtcaataatgtggaggcaactcttttgttgttgaaaaatggggcc
aaccgagacatgcaggacaacaaggaagagacacctctgtttcttgctgcccgggagggg
agctatgaagcagccaagatcctgttagaccattttgccaatcgagacatcacagaccat
atggatcgtcttccccgggatgtggctcgggatcgcatgcaccatgacattgtgcgcctt
ctggatgaatacaatgtgaccccaagccctccaggcaccgtgttgacttctgctctctca
cctgtcatctgtgggcccaacagatctttcctcagcctgaagcacaccccaatgggcaag
aagtctagacggcccagtgccaagagtaccatgcctactagcctccctaaccttgccaag
gaggcaaaggatgccaagggtagtaggaggaagaagtctctgagtgagaaggtccaactg
tctgagagttcagtaactttatcccctgttgattccctagaatctcctcacacgtatgtt
tccgacaccacatcctctccaatgattacatcccctgggatcttacaggcctcacccaac
cctatgttggccactgccgcccctcctgccccagtccatgcccagcatgcactatctttt
tctaaccttcatgaaatgcagcctttggcacatggggccagcactgtgcttccctcagtg
agccagttgctatcccaccaccacattgtgtctccaggcagtggcagtgctggaagcttg
agtaggctccatccagtcccagtcccagcagattggatgaaccgcatggaggtgaatgag
acccagtacaatgagatgtttggtatggtcctggctccagctgagggcacccatcctggc
atagctccccagagcaggccacctgaagggaagcacataaccacccctcgggagcccttg
ccccccattgtgactttccagctcatccctaaaggcagtattgcccaaccagcgggggct
ccccagcctcagtccacctgccctccagctgttgcgggccccctgcccaccatgtaccag
attccagaaatggcccgtttgcccagtgtggctttccccactgccatgatgccccagcag
gacgggcaggtagctcagaccattctcccagcctatcatcctttcccagcctctgtgggc
aagtaccccacacccccttcacagcacagttatgcttcctcaaatgctgctgagcgaaca
cccagtcacagtggtcacctccagggtgagcatccctacctgacaccatccccagagtct
cctgaccagtggtcaagttcatcaccccactctgcttctgactggtcagatgtgaccacc
agccctacccctgggggtgctggaggaggtcagcggggacctgggacacacatgtctgag
ccaccacacaacaacatgcaggtttatgcgtga
DBGET
integrated database retrieval system
