Pan paniscus (bonobo): 100992707
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Entry
100992707 CDS
T02283
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
pps
Pan paniscus (bonobo)
Pathway
pps00562
Inositol phosphate metabolism
pps01100
Metabolic pathways
pps04014
Ras signaling pathway
pps04015
Rap1 signaling pathway
pps04020
Calcium signaling pathway
pps04024
cAMP signaling pathway
pps04070
Phosphatidylinositol signaling system
pps04919
Thyroid hormone signaling pathway
pps04933
AGE-RAGE signaling pathway in diabetic complications
pps05205
Proteoglycans in cancer
Module
pps_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
pps00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
100992707 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100992707 (PLCE1)
04015 Rap1 signaling pathway
100992707 (PLCE1)
04020 Calcium signaling pathway
100992707 (PLCE1)
04070 Phosphatidylinositol signaling system
100992707 (PLCE1)
04024 cAMP signaling pathway
100992707 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100992707 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100992707 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100992707 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pps04131
]
100992707 (PLCE1)
Enzymes [BR:
pps01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
100992707 (PLCE1)
Membrane trafficking [BR:
pps04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
100992707 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
100992707 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
100992707
NCBI-ProteinID:
XP_034787015
Ensembl:
ENSPPAG00000033051
LinkDB
All DBs
Position
8:106023546..106361193
Genome browser
AA seq
2316 aa
AA seq
DB search
MTSEEITASVLIPVTQRKVVSAQSAADESSEKVSDINISKAHTVRRSGETSHTISRLNKL
KEEPSGSNLPKILSIAREKIVSDENSNEKCWEKIMPDSAKNLNINCNNILRNHQHGLPQR
QFYEMYNSVAEEDLCLETGIPSPLERKVFPGIQLELDRPSMGISPLGNQSAIIETGRAHP
DSRRAVFHFHYEVDRRMSDTFCTLSENLILDDCGNCVPLPGGEEKQKKNYVAYTCKLMEL
AKNCDNKNEQLQCDHCDTLNDKYFCFEGSCEKVDMVYSGDSFCRKDFTDSQAAKTFLSHF
EDFPDNCDDVEEDAFKNKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLTA
WSYIDQKRNGALLPCERVMEPPSTVEIRQDGSQHLSEAQWYPIYNAVRREETENTVGSLL
HFLTKLPASETAHGRISVGPCLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGAR
SGLLSTFGGSTGRMMLKERQPGPSVANSNALPSSSAGISKELIDLQPLIQFPEEVASILM
EQEQTIYRRVLPVDYLCFLTRDLGTPECQSSLPCLKASISASILTTQNGEHNALEDLVMR
FNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMW
QFMDQSDIETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGA
SSLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQVIRSCNRS
LETDEEDSPSEGNSSRKSSLKDKSRWQFIIGDLLDSDNDIFEQSKEYDSRGSEDSQKAFD
HGTELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWVKPTTAS
PASSKAKLGVLNNTAEPGKFPLLGNAGLSSLTEGVLDLFAVKAVYMGHPGIDIHTVCVQN
KLGSMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQ
QWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSARNPSPGTSAKNAEKPNMQRNNTLG
ISTTKKKKKILMRGESGEVTDDEMATRKAKMHKECRSRSGSDPQDINEQEESEVNAIANP
PNPLPSRRAHSLTTAGSPNLAAGTSSPIRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGGM
KGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCNRSGSESAPLYTNLTI
DENTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLG
IFGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENF
ASKNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDC
WDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEI
FKTVFGEKLVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLA
SMQAQAYNGGNANPPPANNEEEEDEEDEYDYDYESLSDADVLTASPAPNGQEDNILEDRP
ENKSCNDKLQFEYNEEIPKRIKKADNSACNKGKVYDMELGEEFYLDQNKKESRQIAPELS
DLVIYCQAVKFPGLSTLNASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCE
GIRQTWEESSSPLNPATSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLR
TYPAATRIDSSNPNPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLW
DKNCPMYQKFSPLERDLDSMDPAVYSLTIVSGQNVCPSNSMGSPCIEVDVLGMPLDSCHF
RTKPIHRNTLNPMWNEQFLFRVHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHL
QLRNLHNEVLEISSLFINSRRMEENSSGNTMSASSMFNTEERKCLQTHRVTVHGVPGPEP
FTVFTINGGTKAKQLLQQILTNEQDIKPVTTDYFLMEEKYFISKEKNECRKQPFQRAIGP
EEEIMQILSSWFPEEGYVGRIVLKTQQENLEEKNIVQDDKEVILSSEEESFFVQVHDVSP
EQPRTVIKAPRVSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKTTTPK
SSQRVLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKSTKQP
RGLTSPSQLLTSESIQTKEEKPVGGLSSSDTMDYRQ
NT seq
6951 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaataacagcttctgttcttatacctgtgactcagagaaaagtggtt
tctgcccagtcggctgcagatgaaagtagtgaaaaggtctcagacatcaatatttcaaaa
gcacatactgtcagacgaagtggggagacttctcataccatctcacgactgaacaaactt
aaagaagaaccttctggaagcaacttgccaaagattctctcaatagcaagggagaaaata
gtgagtgatgagaacagtaatgaaaaatgttgggagaaaatcatgccagattctgcaaaa
aaccttaacattaactgcaacaacatattgagaaaccatcagcatggccttcctcagaga
cagttttatgaaatgtacaactctgttgctgaggaagacttgtgtttagaaactggaatt
ccttctccactggaaagaaaggtgttccctggaattcaactggaactagacagaccttcc
atgggcattagtcctttaggaaatcagtcagcgatcatagagacaggcagagcacaccct
gacagcagaagggcagtatttcattttcattatgaagttgacagaagaatgtcagacact
ttctgtaccctatcagaaaacttaattttagacgattgtggaaattgtgtaccactacct
gggggtgaggagaagcaaaagaaaaactatgtggcatatacctgtaaactgatggaattg
gccaaaaattgtgataataagaatgagcagctgcagtgtgatcattgtgacaccttgaat
gataaatacttttgctttgaaggctcttgcgagaaggttgacatggtatattcaggtgat
agcttttgtaggaaagactttactgacagtcaagctgccaagacctttttgagccatttt
gaggacttccctgataattgtgatgatgtagaagaagatgcttttaaaaacaaaaaggag
cgatccactttgttagtcaggagattctgtaaaaatgacagagaagttaagaaatctgtg
tatactggaacaagagcaattgtgagaactctgccttctggccacattgggctgactgca
tggagttacatagatcagaagagaaatggtgccttactgccttgtgagagagtaatggaa
cccccgtcaacagtggagataaggcaagatgggagccaacatctatcagaagcccagtgg
tatcctatctacaatgcagtgagaagagaagaaacagaaaatacagttggatctctactc
catttcctcaccaagctcccagcctccgagacagcccatggaaggataagcgttggtcca
tgcttaaagcaatgtgtccgagacactgtatgtgagtatcgcgccaccctccaaaggact
tcaatatcgcagtacatcaccggttctctcctagaagcaaccacgtctttgggagcaaga
agtggccttctcagtacttttggaggatccactggacgaatgatgctgaaagaacgccag
ccaggcccctctgtggccaattccaatgccctcccttcaagttcagctgggatcagcaag
gagctgatcgatctgcagcctctcatccagttcccagaggaagtcgccagcatcctgatg
gagcaagagcagactatttaccgcagggtcttgccagtcgactacctttgcttcttaaca
cgggacttgggcactcctgaatgccagagctccttgccctgcctcaaagcatccatctca
gcgtcgattcttaccactcagaatggagagcacaatgcccttgaagatctggtgatgagg
tttaatgaggtgagctcctgggtgacatggctgatcctcacggcaggctccatggaggag
aagcgagaagtcttttcatatttggtgcatgtggccaaatgctgctggaacatgggcaac
tacaacgctgtcatggagttcttggctggcctcaggtcaagaaaagttttaaaaatgtgg
cagttcatggaccagtctgatattgagaccatgaggagcctgaaggatgctatggcccag
catgagtcctcttgtgagtacagaaaggtggtgacacgtgccctgcacatccctggctgt
aaggtggttccattctgtggggtgtttctgaaggagctctgtgaagtgcttgacggcgcc
tccagcctcatgaagctttgcccacggtacaattcccaagaagaaactttagagtttgta
gcagattacagtggacaagataatttcttacaacgagtgggacaaaatggcttaaagaat
tcggagaaggagtccactgtcaacagcatctttcaggtcatccggagctgcaatcgaagt
ctggagacagacgaggaggacagccccagtgaaggaaacagctccaggaaaagctccttg
aaggataaaagccgatggcagtttataattggagatttgttggattcagacaatgacatc
tttgagcaatccaaagaatacgactctcgtggttcagaggattcacagaaggccttcgac
catgggacggagctcatcccttggtacgtgctgtccatccaagccgatgtgcaccagttc
ctgctgcagggggccacggtcatccactacgaccaggacacacacctctctgcccgttgc
ttcctccagcttcagcccgacaatagcaccttgacctgggtaaagcccacaactgcctcc
ccagccagcagtaaagcaaaacttggtgtacttaataacacagctgagcctggaaaattc
ccactactgggtaatgctggattaagtagcctgacggaaggggtcttggatctttttgca
gtgaaggctgtatacatgggccaccctggcattgatatacacactgtgtgtgttcagaac
aaactgggtagcatgttcctgtcagagactggtgtgacattgctctatgggcttcagacc
acagacaacagattattgcacttcgtggcaccaaagcacacagctaaaatgctcttcagt
ggattattggaactcactagagctgtgagaaagatgaggaaattccctgaccaaagacag
cagtggctgcggaaacagtatgtcagcctttatcaggaggatggacggtatgaaggccca
actttggctcacgctgtggagttgtttggtggcagacggtggagtgctcgaaaccccagc
cccggaacatcagcaaagaatgctgagaagcccaatatgcagagaaacaataccctgggc
ataagcactaccaagaaaaagaagaaaatcctcatgaggggtgagagtggagaggtaact
gacgatgagatggcaacccgaaaggccaagatgcacaaagagtgtcgaagccggagtggt
tctgatcctcaagacattaatgaacaagaagaatcagaggtgaatgccatcgctaaccct
ccaaaccccctcccttccagaagagcccactctttgaccacagctgggtcccccaacttg
gctgccgggacgtcatctcccatcaggccagtgtcctcccctgtgctgtcttcttcaaac
aagagcccatccagtgcttggagcagtagtagctggcacgggcggatcaaaggcggcatg
aagggatttcagagcttcatggtttcagatagcaacatgagttttgttgaatttgttgag
ctgttcaaatcgttcagtgtcaggagccgcaaggacctgaaggatctgtttgatgtctat
gcagtgccctgcaaccgatctggctctgagtcagccccactctacaccaacctgacaatt
gatgaaaacaccagcgatcttcagcctgacctagatctgttgaccagaaatgtctcggat
ttggggttgttcattaagagtaaacagcagctatcggacaaccagaggcagatatctgat
gccattgctgctgcaagcattgtgacaaatggcactgggattgagagcacatctctgggc
atttttggggtgggcatacttcagctcaacgatttcctcgtgaattgccaaggagaacac
tgcacttatgatgaaatcctcagcatcatccagaagttcgagcctagcatcagtatgtgt
catcagggactaatgtcatttgaagggtttgccaggtttctgatggataaagaaaatttt
gcctcaaaaaatgatgagtcacaggagaacattaaagaactgcagctacccctctcatac
tattacatcgaatcttcgcacaatacctacctcacgggccatcagctcaaaggagaatcc
tcggtagaactctacagccaggtccttttgcaaggctgtcgaagtgtagaattggactgc
tgggacggagacgatgggatgcccatcatttatcatggacatacgctgacaaccaagatc
cccttcaaggaagtggttgaagccattgatcgcagtgccttcatcaactctgacctgcca
atcatcatatcgattgagaaccactgttcattgcctcagcaacgaaaaatggcagaaatt
ttcaagactgtgtttggagaaaagctggtgactaaattcttatttgagactgatttttca
gatgatccaatgcttccttcacctgaccaactcagaaagaaagttcttcttaaaaacaag
aagctaaaagcccatcagacgccagtggatatcttaaagcaaaaggctcatcagttagca
tctatgcaagcgcaggcttataatggtgggaatgccaaccccccacctgccaataatgag
gaagaggaagatgaggaggacgaatatgattatgactatgaatccctttctgatgcagat
gtccttactgcctcccctgctcctaacggtcaggaagacaacattctggaagacagacct
gaaaataaatcatgtaatgacaagcttcagtttgaatataatgaagaaatcccaaagagg
ataaagaaagcagataactctgcttgcaacaaaggaaaggtttatgatatggaactggga
gaagaattttatcttgatcagaataaaaaggaaagcagacagattgcaccagagctttct
gaccttgtaatctattgtcaagcagtaaaatttccaggactgtcaactctaaatgcatct
ggctctagcagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaatccgggc
agaatgagcccaggggagacagcatcatttaacaaaacatctggaaaaagttcctgtgaa
ggcattcgacagacctgggaggaatcttcttcccctctcaacccagccacgtccctcagt
gctatcattagaactcccaaatgttatcatatctcgtcgctgaatgaaaatgccgccaaa
cgtctgtgtcgcaggtattctcagaaactgatccagcacaccgcctgtcagctgctgaga
acttaccctgctgccacccgcatcgactcttccaacccgaaccccctcatgttctggctc
catgggatacagctcgtggcactcaactaccagaccgatgatctccctttacatttaaat
gctgcaatgtttgaggcaaatggtggttgtggttatgttttgaaacctccagttctgtgg
gacaagaactgccccatgtatcagaagttttctccactagaaagagatctggacagcatg
gatcctgcagtctattctttaactattgtctctggtcagaatgtgtgccccagtaatagc
atgggaagcccgtgcattgaagtcgacgtcctgggcatgcctctggacagctgccatttc
cgcacaaagcccatccatcgaaacaccctgaaccccatgtggaacgagcagtttctgttc
cgcgttcacttcgaagatcttgtatttcttcgttttgcagttgtggaaaacaatagttca
gcggtaactgctcagagaatcattccactgaaagctttaaaacgaggatatcgacatctt
cagctgcgaaaccttcacaatgaagtcttggagatttctagtttattcattaacagcaga
aggatggaagaaaattcctctggcaataccatgtcagcctcttcgatgtttaatacagaa
gaaagaaaatgtttgcagactcacagagtcacggtgcatggggtcccagggccagagccc
tttaccgttttcactattaatggaggcaccaaggcaaagcagcttctgcagcaaattctg
acaaatgaacaagacatcaaacctgttaccacagactattttttgatggaagaaaaatat
tttatatctaaagaaaagaatgaatgtaggaaacaaccattccagagagccattggtcca
gaagaggagatcatgcaaattttaagcagctggtttccagaagagggatacgtgggcagg
attgtcttaaaaacccagcaggaaaacctagaagagaaaaacattgttcaagatgacaaa
gaggtgatcttgagctcagaggaggagagtttctttgtccaagtgcatgatgtttctcca
gagcaacctcgaacagtcatcaaagcaccccgcgtcagcactgcacaggatgtcattcag
cagaccttatgcaaagccaaatattcctacagcatcctgagcaaccccaatccaagcgac
tatgtgcttttggaagaggtggtgaaagacactaccaacaagaagaccaccacaccaaag
tcctctcagcgggtccttctggatcaggagtgtgtgtttcaagcccaaagcaagtggaaa
ggtgcaggaaaattcatccttaagctaaaggagcaggtgcaggcatctcgagaagataaa
aagaaaggcatttctttcgcaagtgaactcaagaagctcaccaagtcaactaaacagccc
cgaggacttacatcaccttctcagctcttgacctcagaaagtatccaaaccaaggaggag
aaacctgtgggtggcttgtcctccagtgacacaatggattaccgacagtga
DBGET
integrated database retrieval system
