| Entry |
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| Symbol |
DICER1
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| Name |
(RefSeq) endoribonuclease Dicer isoform X1
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| KO |
| K11592 | endoribonuclease Dicer [EC:3.1.26.-] |
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| Organism |
pps Pan paniscus (bonobo)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:pps00001]
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100995969 (DICER1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:pps03036]
100995969 (DICER1)
Chromosome and associated proteins [BR:pps03036]
Eukaryotic type
Gene silencing
RISC (RNA-induced silencing complex)
100995969 (DICER1)
microRNA pathway
RISC loading complex
100995969 (DICER1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
15:complement(96234748..96307196)
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| AA seq |
1922 aa
MKNPALQPLSMAGLQLMTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALDHNT
IVCLNTGSGKTFIAVLLTKELSYQIRGDFSRNGKRTVFLVNSANQVAQQVSAVRTHSDLK
VGEYSNLEVNASWTKERWNQEFTKHQVLIMTCYVALNVLKNGYLSLSDINLLVFDECHLA
ILDHPYREIMKLCENCPSCPRILGLTASILNGKCDPEELEEKIQKLEKILKSNAETATDL
VVLDRYTSQPCEIVVDCGPFTDRSGLYERLLMELEEALNFINDCNISVHSKERDSTLISK
QILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFTDTFLRKIHALCE
EHFSPASLDLKFVTPKVIKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDE
DEEIEEKEKPETNFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFIT
GHGIGKNQPRNKQMEAEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLP
TEYRSYVQSKGRARAPISNYIMLADTDKIKSFEEDLKTYKAIEKILRNKCSKSVDTGETD
IDPVMDDDDVFPPYVLRPDDGGPRVTINTAIGHINRYCARLPSDPFTHLAPKCRTRELPD
GTFYSTLYLPINSPLRASIVGPPMSCVRLAERVVALICCEKLHKIGELDDHLMPVGKETV
KYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRDSYPRPDQPCYLYVIGMVLTTP
LPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFVLSL
QMLELITRLHQYIFSHILRLEKPALEFKPTDADSAYCVLPLNVVNDSSTLDIDFKFMEDI
EKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKF
PSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKR
KAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDAGV
GVRSLPADFRYPNLDFGWKKSIDSKSFISISNSSSAENDNYCKHSTIVPENAAHQGANRT
SSLENHDQMSVNCRTLLSESPGKLHVEVSADLTAINGLSYNQNLANGSYDLANRDFCQGN
QLNYYKQEIPVQPTTSYSIQNLYSYENQPQPSDECTLLSNKYLDGNANKSTSDGSPVMAV
MPGTTDTIQVLKGRIDSEQSPSIGYSSRTLGPNPGLILQALTLSNASDGFNLERLEMLGD
SFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNW
LPPGYVVNQDKSNTDKWEKDEMTKDCMLANGKLDEDYEEEDEEEESLMWRAQKEEADYED
DFLEYDQEHIRFIDNMLMGSGAFVKKISLSPFSTTDSAYEWKMPKKSSLGSMPFSSDFED
FDYSSWDAMCYLDPSKAVEEDDFVVGFWNPSEENCGVDTGKQSISYDLHTEQCIADKSIA
DCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTDREKALCPTRENFNSQQKNLSVS
CAAASVASSRSSVLKDSEYGCLKIPPRCMFDHPDADKTLNHLISGFENFEKKINYRFKNK
AYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALV
NNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQLEKNEMQGMDSELRRSEEDEEKEE
DIEVPKAMGDIFESLAGAIYMDSGMSLETVWQVYYPMMRPLIEKFSANVPRSPVRELLEM
EPETAKFSPAERTYDGKVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLKANQPQVP
NS |
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| NT seq |
5769 nt +upstreamnt +downstreamnt
atgaaaaaccctgctttgcaacccctcagcatggcaggcctgcagctcatgacccctgct
tcctcaccaatgggtcctttctttggactgccatggcaacaagaagcaattcatgataac
atttatacgccaagaaaatatcaggttgaactgcttgaagcagctctggatcataatacc
atcgtctgtttaaacactggctcagggaagacatttattgcagtactactcactaaagag
ctgtcctatcagatcaggggagacttcagcagaaatggaaaaaggacggtgttcttggtc
aactctgcaaaccaggttgctcaacaagtgtcagctgtcagaactcattcagatctcaag
gttggggaatactcaaacctagaagtaaatgcatcttggacaaaagagagatggaaccaa
gagtttactaagcaccaggttctcattatgacttgctatgtcgccttgaatgttttgaaa
aatggttacttatcactgtcagacattaaccttttggtgtttgatgagtgtcatcttgca
atcctagaccacccctatcgagaaattatgaagctctgtgaaaattgtccatcatgtcct
cgcattttgggactaactgcttccattttaaatgggaaatgtgatccagaggaattggaa
gaaaagattcagaaactagagaaaattcttaagagtaatgctgaaactgcaactgacctg
gtggtcttagacaggtatacttctcagccatgtgagattgtggtggattgtggaccattt
actgacagaagtgggctttatgaaagactgctgatggaattagaagaagcacttaatttt
atcaatgattgtaatatatctgtacattcaaaagaaagagattctactttaatttcgaaa
cagatactatcagactgtcgtgccgtattggtagttctgggaccctggtgtgcagataaa
gtagctggaatgatggtaagagaactacagaaatacatcaaacatgagcaagaggagctg
cacaggaaatttttattgtttacagacactttcctaaggaaaatacatgcactatgtgaa
gagcacttctcacctgcctcacttgacctgaaatttgtaactcctaaagtaatcaaactg
ctcgaaatcttacgcaaatataaaccatatgagcgacagcagtttgaaagcgttgagtgg
tataataatagaaatcaggataattatgtgtcatggagtgattctgaggatgatgatgag
gatgaagaaattgaagaaaaagagaagccagagacaaattttccttctccttttaccaac
attttgtgcggaattatttttgtggaaagaagatacacagcagttgtcttaaacagattg
ataaaggaagctggcaaacaagatccagagctggcttatatcagtagcaattttataact
ggacatggcattgggaagaatcagcctcgcaacaaacagatggaagcagaattcagaaaa
caggaagaggtacttaggaaatttcgagcacatgagaccaacctgcttattgcaacaagt
attgtagaagagggtgttgatataccaaaatgcaacttggtggttcgttttgatttgccc
acagaatatcgatcctatgttcaatctaaaggaagagcaagggcacccatctctaattat
ataatgttagcggatacagacaaaataaaaagttttgaagaagaccttaaaacctacaaa
gctattgaaaagatcttgagaaacaagtgttccaagtcggttgatactggtgagactgac
attgatcctgtcatggatgatgatgacgttttcccaccatatgtgttgaggcctgacgat
ggtggtccacgagtcacaatcaacacggccattggacacatcaatagatactgtgctaga
ttaccaagtgatccgtttactcatctagctcctaaatgcagaacccgagagttgcctgat
ggtacattttattcaactctttatctgccaattaactcacctcttcgagcctccatcgtt
ggtcctccaatgagctgtgtacgattggctgaaagagttgtagctctcatttgctgtgag
aaactgcacaaaattggcgaactggatgaccatttgatgccagttgggaaagagactgtt
aaatatgaagaagagcttgatttgcatgatgaggaagagaccagtgttccaggaagacca
ggttccacgaaacgaaggcagtgctacccaaaagcaattccagagtgtttgagggatagt
tatcccagacctgatcagccctgttacctgtatgtgataggaatggttttaactacacct
ttacctgatgaactcaactttagaaggcggaagctctatcctcctgaagataccacaaga
tgctttggaatactgacggccaaacccatacctcagattccacactttcctgtgtacaca
cgctctggagaggttaccatatccattgagttgaagaagtctggtttcgtgttgtctcta
caaatgcttgagttgattacaagacttcaccagtatatattctcacatattcttcggctt
gaaaaacctgcactagaatttaaacctacagacgctgattcagcatactgtgttctacct
cttaatgttgttaatgactccagcactttggatattgactttaaattcatggaagatatt
gagaagtctgaagctcgcataggcattcccagtacaaagtatacaaaagaaacacccttt
gtttttaaattagaagattaccaagatgccgttatcattccaagatatcgcaattttgat
cagcctcatcgattttatgtagctgatgtgtacactgatcttaccccactcagtaaattt
ccttcccctgagtatgaaacttttgcagaatattataaaacaaagtacaaccttgaccta
accaatctcaaccagccactgctggatgtggaccacacatcttcaagacttaatcttttg
acacctcgacatttgaatcagaaggggaaagcgcttcctttaagcagtgctgagaagagg
aaagccaaatgggaaagtctgcagaataaacagatactggttccagaactctgtgctata
catccaattccagcatcactgtggagaaaagctgtttgtctccccagcatactttatcgc
cttcactgccttttaactgcagaggagctaagagcccagactgccagcgatgctggcgtg
ggagtcagatcacttcctgcggattttagataccctaacttagacttcgggtggaaaaaa
tctattgacagcaaatctttcatctcaatttctaactcctcttcagctgaaaatgataat
tactgtaagcacagcacaattgtccctgaaaatgctgcacatcaaggtgctaatagaacc
tcctctctagaaaatcatgaccaaatgtctgtgaactgcagaacgttgctcagcgagtcc
cctggtaagctccacgttgaagtttcagcagatcttacagcaattaatggtctttcttac
aatcaaaatctcgccaatggcagttatgatttagctaacagagacttttgccaaggaaat
cagctaaattactacaagcaggaaatacccgtgcaaccaactacctcatattccattcag
aatttatacagttacgagaaccagccccagcccagcgatgaatgtactctcctgagtaat
aaataccttgatggaaatgctaacaaatctacctcagatggaagtcctgtgatggccgta
atgcctggtacgacagacactattcaagtgctcaagggcaggatagattctgagcagagc
ccttctattgggtactcctcaaggactcttggccccaatcctggacttattcttcaggct
ttgactctgtcaaacgctagtgatggatttaacctggagcggcttgaaatgcttggcgac
tcctttttaaagcatgccatcaccacatatctattttgcacttaccctgatgcgcatgag
ggccgcctttcatatatgagaagcaaaaaggtcagcaactgtaatctgtatcgccttgga
aaaaagaagggactgcccagccgcatggtggtgtcaatatttgatccccctgtgaattgg
cttcctcctggttatgtagtaaatcaagacaaaagcaacacagataaatgggaaaaagat
gaaatgacaaaagactgcatgctggcgaatggcaaactggatgaggattacgaggaggag
gatgaggaggaggagagcctgatgtggagggctcagaaggaagaggctgactatgaagat
gatttcctggagtatgatcaggaacatatcagatttatagataatatgttaatggggtca
ggagcttttgtaaagaaaatctctctttctcctttttcaaccactgattctgcatatgaa
tggaaaatgcccaaaaaatcctccttaggtagtatgccattttcatcagattttgaggat
tttgactacagctcttgggatgcaatgtgctatctggatcctagcaaagctgttgaagaa
gatgactttgtggtggggttctggaatccatcagaagaaaactgtggtgttgacacggga
aagcagtccatttcttacgacttgcacactgagcagtgtattgctgacaaaagcatagcg
gactgtgtggaagccctgctgggctgctatttaaccagctgtggggagagggctgctcag
cttttcctctgttcactggggctgaaggtgctcccggtaattaaaaggactgatcgggaa
aaggccctgtgccctactcgggagaatttcaacagccaacaaaagaacctttcagtgagc
tgtgctgctgcttctgtggccagttcacgctcttctgtattgaaagactcggaatatggt
tgtttgaagattccaccaagatgtatgtttgatcatccagatgcagataaaacactgaat
caccttatatcggggtttgaaaattttgaaaagaaaatcaactacagattcaagaataag
gcttaccttctccaggcttttacacatgcctcctaccactacaatactatcactgattgt
taccagcgcttagaattcctgggagatgcgattttggactacctcataaccaagcacctt
tatgaagacccgcggcagcactccccgggggtcctgacagacctgcggtctgccctggtc
aacaacaccatctttgcatcgctggctgtaaagtacgactaccacaagtacttcaaagct
gtctctcctgagctcttccatgtcatcgatgactttgtgcagtttcagcttgagaagaat
gaaatgcaaggaatggattctgagcttaggagatctgaagaggatgaagagaaagaagag
gatattgaagttccaaaggccatgggggatatttttgagtcgcttgctggtgccatttac
atggatagtgggatgtcactggagacagtctggcaggtgtactatcccatgatgcggcca
ctaatagaaaagttttctgcaaatgtaccccgttcccctgtgcgagaattgcttgaaatg
gaaccagaaactgccaaatttagcccggctgagagaacttacgacgggaaggtcagagtc
actgtggaagtagtaggaaaggggaaatttaaaggtgttggtcgaagttacagaattgcc
aaatctgcagcagcaagaagagccctccgaagcctcaaagctaatcaacctcaggttccc
aatagctga |
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