Podospora pseudocomata: QC762_119640
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Entry
QC762_119640 CDS
T09797
Symbol
LEU4
Name
(RefSeq) 2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase)
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ppsd
Podospora pseudocomata
Pathway
ppsd00290
Valine, leucine and isoleucine biosynthesis
ppsd00620
Pyruvate metabolism
ppsd01100
Metabolic pathways
ppsd01110
Biosynthesis of secondary metabolites
ppsd01210
2-Oxocarboxylic acid metabolism
ppsd01230
Biosynthesis of amino acids
Module
ppsd_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ppsd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
QC762_119640 (LEU4)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
QC762_119640 (LEU4)
Enzymes [BR:
ppsd01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
QC762_119640 (LEU4)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-GeneID:
87906308
NCBI-ProteinID:
XP_062749485
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Position
1
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AA seq
612 aa
AA seq
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MPMLKDPSKKYKRFQPLNLPDRQWPDKVIEKAPRWLATDLRDGNQSLVDPMQNGDQKWRY
FQMLTELGYKEIEVSFPSASQTDFDFTRRLIETPGAVPDDVWLQVLSPCREDLIRRTVDS
LKGAKKAIVHIYLATSECFRRVIFGFSEDESVVLASKCAALVRSLTKDDPSQSGTEWAFE
FSPETFSDTSPEFVVRICEAVKEAWGPTKENPIIFNLPATVEMSTPNVYADQIEYFCRNI
SEREKICVSLHPHNDRGCAVAAAELAQMAGADRVEGCLFGNGERTGNVDLVTLALNLYTQ
GVTPNIDFSDLQKVIKTVEECNKIEVHPRAPYGGSLVVCAFSGSHQDAIKKGFQIREKEG
KEYDDHWQIPYLPLDPKDIGRDYQAVIRVNSQSGKGGAAWVIQQNLHLDLPRGLQVAFAK
VVQAMAEQKGRELLPTEITDLFRETYHLDKNSRFNIVDYNINPDRSASPAPPAPGKTQDT
KNLMRVFEGVILIDGKEYKLRGRGNGPISSAANALRTIGIDLDVQDYKEHAVGRGREVKA
ATFIECVAPGVEEKVWGVGIHEDVVQSSLIALLSAASNFASSRHGSPIIPKQTLTNGGLQ
VPDMQSLEHKAE
NT seq
1839 nt
NT seq
+upstream
nt +downstream
nt
atgcctatgcttaaggatccctccaagaagtacaagaggttccaacctctgaacctccca
gaccgtcaatggccagacaaagtcatcgagaaggccccaagatggctggcaacagatttg
agagacggcaaccagagtctggttgaccccatgcagaacggtgatcaaaaatggcgttac
ttccagatgctcaccgagctcggctacaaggagattgaagtatcctttccctccgcttcc
cagaccgatttcgacttcacaagacgtctgatcgagaccccgggcgccgtacccgacgat
gtctggctccaagtcctgtcgccctgcagagaggacctcattcgccgcacagtcgattcg
ctgaagggagccaagaaggccattgtccacatctatctcgctaccagcgaatgtttccgg
agggttatctttggattctcggaagatgagagcgtggttcttgcttccaagtgtgcggct
ctggtacggtcactgaccaaggacgatccgtcgcagtcgggtaccgagtgggcattcgag
ttcagtcccgaaactttctcggataccagcccagaatttgttgtgaggatctgcgaggct
gtcaaggaggcatggggcccaaccaaggagaaccccatcattttcaacctcccggcaacc
gtcgagatgtccacccccaacgtctatgccgaccagatcgagtacttctgccgcaacatc
tccgagcgcgagaagatctgcgtgtcccttcaccctcacaacgaccgcggctgtgcggtt
gctgcggccgagctggcccagatggcaggagccgacagagtagaggggtgcctgtttggc
aatggggagcggacaggaaacgttgatctggtcactcttgccctcaacctttacacacag
ggcgtgactcccaacatcgacttctcggacctccaaaaggtcatcaagacagtggaggag
tgcaacaagatcgaggttcacccacgtgcgccgtacggtgggtctctggtggtgtgcgct
ttcagcggatctcaccaggatgctatcaagaagggcttccaaatccgggagaaggagggt
aaggagtacgacgaccactggcagattccttacctccctctggaccccaaggatattggt
cgcgactaccaggccgtcatccgcgtcaactcgcagtctggaaagggcggtgccgcttgg
gttatccagcaaaacctgcatctggacctcccacgtggtctacaagtcgctttcgccaag
gtcgtacaggctatggcggagcaaaagggtcgcgagctccttcccactgagattactgac
ctcttccgggagacttaccaccttgacaagaactcccgcttcaacattgttgactacaac
atcaaccccgaccgttccgcctctcccgcacctccagcccccggcaagacccaggatact
aagaatctgatgagagtcttcgagggtgtcattttgattgacggcaaagagtacaagctc
cgcggccgtggcaacggtccgatctccagtgccgcaaacgctctccgaaccattggtatt
gacttggatgtccaggactacaaggagcatgctgtcggtcggggacgggaagtcaaggcg
gcaacattcatcgagtgcgtggccccgggtgtggaagagaaggtttggggagtgggcatc
cacgaggatgtagtccagagctcgctgattgcgctgcttagtgctgccagcaactttgcc
agcagccgccatgggagccctattattcccaagcagactcttaccaatggcggcctccaa
gttccggacatgcagtccctggagcacaaggccgaataa
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