KEGG   Pungitius pungitius (ninespine stickleback): 119222111
Entry
119222111         CDS       T07626                                 
Symbol
plcb3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
ppug  Pungitius pungitius (ninespine stickleback)
Pathway
ppug00562  Inositol phosphate metabolism
ppug01100  Metabolic pathways
ppug04020  Calcium signaling pathway
ppug04070  Phosphatidylinositol signaling system
ppug04081  Hormone signaling
ppug04082  Neuroactive ligand signaling
ppug04261  Adrenergic signaling in cardiomyocytes
ppug04270  Vascular smooth muscle contraction
ppug04310  Wnt signaling pathway
ppug04371  Apelin signaling pathway
ppug04540  Gap junction
ppug04621  NOD-like receptor signaling pathway
ppug04912  GnRH signaling pathway
ppug04916  Melanogenesis
Module
ppug_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ppug00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    119222111 (plcb3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    119222111 (plcb3)
   04371 Apelin signaling pathway
    119222111 (plcb3)
   04020 Calcium signaling pathway
    119222111 (plcb3)
   04070 Phosphatidylinositol signaling system
    119222111 (plcb3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    119222111 (plcb3)
   04081 Hormone signaling
    119222111 (plcb3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    119222111 (plcb3)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    119222111 (plcb3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    119222111 (plcb3)
   04916 Melanogenesis
    119222111 (plcb3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    119222111 (plcb3)
   04270 Vascular smooth muscle contraction
    119222111 (plcb3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ppug04131]
    119222111 (plcb3)
Enzymes [BR:ppug01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     119222111 (plcb3)
Membrane trafficking [BR:ppug04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    119222111 (plcb3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    119222111 (plcb3)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PI-PLC-Y PH_14 PLCB1-4-like_EFh EF-hand_like Peptidase_S46
Other DBs
NCBI-GeneID: 119222111
NCBI-ProteinID: XP_037334357
LinkDB
Position
1:8537196..8574693
AA seq 1265 aa
MAGAKPGVHALQLKPVSVHEALKKGGKFIKWDEPTLEPKLKEPNSGPPTLVTLKVDPDGF
YLYWTGGSNLEVEILDINTIRDTRTGKYAKQPKDAKLREVLGFGKADNVEGKLVTVVHGN
DLVNISFLNFQAMQKDAAKIWTDELFTLATNILSQNASRHTFLLKAYTKLKLQVNQDGKI
PVKNILKMFSDKKRVETALEQCGLVNNRAEGIKPDDFTWDAFQRFLDSLCLRPEIQSIFE
ESGSKRKPFISLDQLMDFINRRQRDSRLNEVLYPPLKREQVRQIMEKYETNASQLERDQI
SLQAFSRYLEGDENSIVPPERLDIIDDMNQPLAHYFINSSHNTYLTVGQLTGLSSVEIYR
QVLLTGCRCVELDCWKGRPHDEEPYITHGFTMTTEIPFKEVIEAIAESAFKTSPYPLILS
FENHVDSAKQQAKMAEYCRTIFGDALLIEPLEKYPLVPGQALPSPQELLGKILIKNKKKH
QHHRPSSSGSIRRRELEEQSSPNNDCPLTDGEGGQLLTNGEEKLAERMVKDFEPRKSLGG
EGESEEDEDDEPTAELKKPNSDEGTASSEVNATEEMSTLVNYIEPVKFKSFEVANKRRKF
FEMSSLVETKGMDTLKSSPIEFVEYNKNQLSRIYPKGTRVDSSNYMPQLFWNVGCQMVAL
NFQTLDLPMQLNMGVFEYNGHSGYLLKPEFMRRTDKHFDPFTENIVDGIVANTVKIKVIS
GQFLTDKKVGVYVEVDIFGLPADTKRKFRTKTSNGNSLDPVWDDEMSVFNKVVLPTLASL
RIAVFEENGKFIGHRILPVSAIRPGYHYINLKNELNQPLLLPSLLVYAEAQDYIPNEHQE
YAEALTNPIKHISQLHKRETQLAALIEDHSEHVPNQPKDGETKMEWEDISQSRPQLPVPL
LEKAPDIIKLPAPAQSPKEDLIATVLAEVQAESIEELKQQKSYLKVLKKQSKEIKEMRKK
HLKKVWNLSKEQKSRNCQLQSDTQRRRSQMEKHLKRSIKRNEPQDPVQRDLTALDQELEK
QTVQLREWQMQELLMLRQQLHSLEREKQQTHLQEALQKLKETAAECQAAQLKKLKETCEK
EKKELQKILDRKRQNSICEAKTRDKDKAETELNEINRKHIQDSVSLIRGLEDAQTRRQDK
LMLRQREVLQQIDDELPLIQSKLERDLEEEYHRLPEEICQHLQLELKSKGLRKDALFSSH
CNNSSPGSGSGSGSGPPSNCSTPSYPSTPDRIPWNRSMDNSMASLADSTSSSTTPVLSEA
EMSFS
NT seq 3798 nt   +upstreamnt  +downstreamnt
atggccggggccaagccgggagtccacgctctgcagctcaagcccgtgtccgtccacgaa
gcgctgaagaaggggggcaaattcatcaaatgggacgagccgactttggagcctaaactc
aaggagcccaacagtgggccgcccaccctagtgaccctgaaagttgacccagatggattc
tacctctactggaccggaggatccaacctggaggtggagattcttgacatcaacaccatc
agggacaccagaacaggaaaatacgccaaacaacctaaggacgccaagctgcgggaggtg
cttggcttcggtaaggcggacaacgttgaagggaagctggtaacggttgtccatggcaac
gacctggtcaacatctccttcctcaacttccaggctatgcagaaagatgcagcaaagatt
tggacagatgagctgttcactttggccacaaacatactttcccagaatgcatcacggcac
accttcctcctcaaagcgtacactaagttaaagctgcaggtgaatcaggatggaaaaatc
cctgtgaagaatattctcaagatgttttcagataaaaagagagtggagacggctctggag
cagtgtggcctcgtcaataaccgggctgagggaataaagccagacgatttcacgtgggac
gccttccagaggtttctcgacagcctctgtctgcggcccgagatacaaagcatcttcgag
gaaagcggctccaagaggaagccgttcatctctctggaccagttgatggacttcattaac
cgcaggcagcgagactccaggctgaacgaggtgctgtacccccccttgaaaagggaacag
gtccgacagatcatggagaaatatgagactaacgccagccagctggagagagaccagatc
agtttgcaggctttcagtcggtatctggaaggcgatgaaaacagcatcgtacctccagag
aggctggatatcatcgacgacatgaaccaaccactggctcactactttatcaattcctcg
cacaacacgtacctcacagtgggtcagctgactggcctgtcttcagtggagatttatagg
caggtgctgctgactggctgtcgctgtgttgagctggactgctggaagggccggcctcac
gacgaggagccttacatcacccacggcttcaccatgaccactgagatcccctttaaggag
gtgattgaggcgatagcagaaagtgctttcaagacatcgccgtaccccctcatcctgtcc
tttgaaaaccacgtagattcggccaagcagcaagccaaaatggcagagtactgcaggacc
atctttggagacgctctgctcattgaaccactggagaagtatccgctggtccccggtcag
gcccttccttctccacaggagttgctgggtaagattctcatcaaaaacaagaagaagcac
cagcaccacagaccctcgagtagcggaagcataagacgcagagagctggaggaacagtcg
tcgcccaacaacgactgcccactgacggacggcgaaggaggccagctcctcaccaacggg
gaggaaaagctggctgagaggatggtcaaagactttgagcctcgcaagtccctcggaggt
gagggggaaagcgaggaggacgaggacgacgagccgacagcggagctgaaaaagccaaac
tccgacgagggcaccgccagcagcgaggtgaacgccaccgaggagatgtccactcttgtc
aactacatcgagcctgtcaaattcaagagcttcgaggtggcaaacaagaggaggaagttc
tttgaaatgtcttcgttggtggagacgaaaggcatggacaccctgaagagctcccccatc
gagtttgtcgagtacaataagaatcagctgagccgaatctaccccaaaggaaccagggtg
gacagctccaattacatgcctcagctcttctggaacgtgggctgccagatggtggcgcta
aacttccaaacgctcgaccttcctatgcagctgaacatgggtgtgtttgagtacaacggc
cacagcggctacctgctgaagcctgagttcatgaggagaacggacaagcactttgaccct
ttcacagaaaacatagtggatggtatcgtcgcaaatactgtcaaaattaaggtgatctcg
ggccagtttctcaccgataaaaaggtgggcgtgtacgtggaagtggacatatttggactt
cctgctgatacaaagaggaagttcagaaccaaaacatccaacgggaactcgctggacccc
gtgtgggacgatgaaatgtctgtgtttaacaaggtggtccttcccacgctggcctctctg
aggatagccgtgtttgaagaaaacggcaagttcattggacaccggatcctcccggtgtcg
gccattagaccgggctaccactacatcaacctgaagaatgagctgaaccagccgctgctc
ctgccctctctcctggtttacgcagaagctcaggactacatccccaatgaacaccaggag
tacgccgaggctctgaccaaccccatcaagcacatcagtcagttgcataagagagagacg
cagctggctgctctcatagaggaccacagcgagcatgtccccaaccagcccaaagacgga
gagacaaagatggagtgggaagacatttcgcaaagtcgaccccaactccccgttccacta
ctggaaaaagcccccgacatcatcaagttacctgcaccggctcaaagtccaaaggaagac
ctcattgccactgttctagcagaggtccaggctgagtccatcgaggagttgaaacagcag
aagagctatctgaaggtgctaaagaaacagagcaaagaaatcaaagagatgcgtaagaaa
cacctcaagaaggtgtggaacctgagcaaggagcagaagagtcggaattgccagcttcag
tccgacacccagaggagacgcagtcagatggagaagcacctcaaacgtagcatcaagaga
aacgagccccaggacccggtgcagcgtgacctgaccgcgttggatcaggagctggagaag
cagacggtccagctgagggaatggcagatgcaagaactgctgatgctccgacaacagctt
cactcactggagagagagaagcaacaaacacacctgcaggaggccttgcagaagttaaag
gagacggccgctgaatgccaagcagctcagctgaagaagctcaaggagacgtgtgaaaaa
gagaagaaagaactccagaaaattctagacaggaagcgacaaaacagcatctgcgaagcc
aagacccgcgacaaagacaaggcggaaacggaactgaatgagatcaacagaaaacacatt
caagactctgtctcgttaatccgcgggctggaggatgctcagacccggaggcaagacaag
ctgatgctgcgtcagcgggaggtgctgcagcaaatagacgatgaacttccactgatccag
tctaagttggaacgggacctggaggaggagtaccacaggctgccggaggagatctgccag
caccttcagctggagctcaagagcaaaggtctccggaaagacgccctgttctcgtcccat
tgcaacaacagcagccccgggtccggctctggctctggctcgggcccgccctccaactgc
tccacgccgtcttacccgtcgacgcccgatcggattccctggaaccggagcatggacaat
agcatggcgtccttggccgattccacctcctcgtccaccactcccgtcctttcagaggcc
gagatgtcgttcagctag

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