Pogoniulus pusillus (red-fronted tinkerbird): 135176659
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Entry
135176659 CDS
T10504
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
ppus Pogoniulus pusillus (red-fronted tinkerbird)
Pathway
ppus00270
Cysteine and methionine metabolism
ppus00480
Glutathione metabolism
ppus01100
Metabolic pathways
ppus01240
Biosynthesis of cofactors
ppus04216
Ferroptosis
Module
ppus_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
ppus00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
135176659 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
135176659 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
135176659 (GCLC)
Enzymes [BR:
ppus01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
135176659 (GCLC)
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Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
135176659
NCBI-ProteinID:
XP_064001889
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Position
7:8445706..8480868
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AA seq
636 aa
AA seq
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MGLLSQGSPLSWEETRRYAEHVRKHGIIQFLHIYRALRDRHKDVLKWGDEVEYMLVKFDH
ENKKVRLALCGEEVLQTLQDKGEKVNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRQEAASVLKENEALCTVTSFPRLGCPGFTLPEYKPTPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFTETFPDDDGEAAKAAKPDYIYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTIDKDIYEHLI
KEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVTFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAV
RQGMFYFRKDICKGGNAVVDGCGSAQNGTCTKMEEYTLMSIDTIINGKEGVFPGLIPILN
SYLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIAQHPDYKQDSVITDEMNY
SLIWKCNQIAQGQAECPELLGVGFNKKQSGNKTGSL
NT seq
1911 nt
NT seq
+upstream
nt +downstream
nt
atgggtctgctgtcgcagggctcgccgctgagctgggaggagacgcggcggtacgcggag
cacgtgcggaagcacggcatcatccagttccttcacatctaccgtgccctgcgcgaccgc
cacaaggacgtcctcaagtggggcgacgaggtggagtatatgttagtgaaatttgaccat
gagaataagaaagtgcgcctggcactctgtggtgaagaagttcttcaaacactgcaagac
aagggtgagaaggtaaaccccaaccacccaacactctggcgaccagaatatggaagctac
atgattgaagggacacctgggcagccatatgggggaaccatgtctgaattcaacactgtg
caagacaacatgaggaaaagacggcaagaggctgcttctgtgctcaaagaaaacgaggct
ctttgcactgtgacatcgtttccaaggttaggctgtccgggctttacgctgccagagtat
aaaccaacgccagtagaaggaggagcttcaaaatccctcttttttccagatgaagccatc
aataaacatcccagatttagtactctgaccagaaacattcggcaccgaagaggagagaag
gttgtgataaatgtacccatatttaaagacaagaacacaccatcaccatttactgagaca
tttcctgatgatgatggcgaagcagcaaaggcagctaaaccggactatatatacatggac
gccatgggttttggaatgggaaactgttgtcttcaggtaacattccaggcttgcagcatt
tctgaagcaaggtatctttatgatcagctggccaccatctgccccattgtgatggccttg
agtgcagcatctccattctacagaggctatgtgtctgatattgactgtcgctggggagta
atctcagcatctgtagatgatcgaacgcgagaggagaggggactagagccactgaagaac
aaccattatagaatcagtaaatccagatatgattccatagacagttatctatctgaatgt
ggtgagaaatacaatgacattgatttgacaatagacaaagatatctacgagcacctgata
aaggaaggtattgaccaccttttggcacagcatattgcacacttgttcattcgagaccca
ttgacgttgtttgaggagaaaatacatctagatgatgcaaatgaatctgaccattttgag
aacattcagtctacaaactggcagacaatgaggtttaagccacctcctccaaattcagat
attggatggagagtggaattcagacctatggaggtccagttaacagactttgaaaactct
gcatatgttacgtttgtggtattgctaaccagagtgattctgtcatataaactggatttt
ctcattcctttgtccaaggtggatgaaaacatgaaggtggcccagaaaagagatgctgtc
cgacagggaatgttttacttcagaaaagatatttgcaaaggtggaaatgctgttgtggat
ggatgtggctctgcacagaatgggacttgcaccaagatggaggaatacaccttaatgagc
attgatacaattatcaatgggaaggaaggagtctttcctggtttgatccctattttgaat
tcctatcttgaaaacatggaagtggatgtggacacaaggtgcaccatcctaaactacctg
aagctaattaaaaagagagcatctggcgaactcatgacagtggctcgctggatgagggaa
ttcattgcacagcatccagactacaagcaggacagtgtgatcaccgatgagatgaactac
agcctcatttggaagtgcaaccaaatcgcacaaggccaggcagagtgccctgaactacta
ggggtagggtttaataagaaacaaagtggaaacaaaactggctctttgtaa
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