Pseudomonas putida DOT-T1E: T1E_0512
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Entry
T1E_0512 CDS
T02181
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
ppx
Pseudomonas putida DOT-T1E
Pathway
ppx00290
Valine, leucine and isoleucine biosynthesis
ppx00660
C5-Branched dibasic acid metabolism
ppx01100
Metabolic pathways
ppx01110
Biosynthesis of secondary metabolites
ppx01210
2-Oxocarboxylic acid metabolism
ppx01230
Biosynthesis of amino acids
Module
ppx_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ppx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
T1E_0512 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
T1E_0512 (leuC)
Enzymes [BR:
ppx01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
T1E_0512 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
T1E_0512 (leuC)
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GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
AFO46370
UniProt:
I7AUQ2
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Position
584045..585478
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AA seq
477 aa
AA seq
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MAGKTLYDKLWEAHEVKRRDDGSSLIYIDRHIIHEVTSPQAFEGLRLANRKPWRIDANIA
TPDHNVPTTPERKGGIEAIVDQVSRLQVQTLDENCDEYGIVEFKMNDERQGIVHVISPEQ
GATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQCLVAKKMKNMLVRVEGQLP
AGVTAKDIVLAVIGKIGTAGGNGHAMEFAGSAIRELSMEGRMTICNMSIEAGARVGLVAT
DATTVAYVEGRPYAPKGEQWKQAVESWKDLVSDDDAVFDTVVELDASQIKPQVSWGTSPE
MVLAVDQRVPDPAAEADLVKRGSIERALKYMGLTANQAITDIKLDRVFIGSCTNSRIEDL
RAAAEIAKGRKVAASVKQAIVVPGSGLVKAQAEREGLDKIFLEAGFEWREPGCSMCLAMN
PDRLESGEHCASTSNRNFEGRQGAGGRTHLVSPAMAAAAAVAGHFIDVRELIQGSAA
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
atggctggcaaaacgctctacgacaaactctgggaagcccatgaggtcaagcgccgtgat
gacggctcgtccttgatctacatcgaccgccacatcatccacgaagtgacgtcgccccag
gccttcgaaggcctgcgcctggccaatcgcaaaccgtggcgtatcgacgccaacatcgcc
acgcctgaccacaacgtaccgaccacgccagagcgcaagggcggtatcgaggcgatcgtc
gaccaggtttcgcgcctgcaagtacagaccctcgacgagaactgtgacgaatacggcatc
gtcgaattcaagatgaatgacgagcgccagggcatcgtccacgtcatcagcccggagcag
ggcgccaccttgccgggcatgaccgtggtctgcggtgactcgcacacctccacccacggc
gctttcggtgccctggcccacggcatcggcacctccgaggtcgagcacgtgctcgccacc
cagtgcctggtcgccaagaagatgaagaacatgctggtgcgcgtggaaggccaattgccg
gccggcgtcaccgccaaggatatcgtcctggccgtgatcggcaagatcggcactgccggt
ggcaacggtcacgccatggaattcgctggcagtgccattcgcgaattgtcgatggaaggc
cgcatgaccatctgcaacatgtccatcgaagccggtgcccgcgttggcttggtggcgacc
gatgccactaccgttgcctacgtcgaagggcgcccgtacgcgccgaagggtgagcagtgg
aagcaagcggtcgaatcgtggaaagacctggtgtcggatgacgatgccgtattcgacacc
gtggtcgagctggatgccagccagatcaagccacaggtcagctggggcacttcgcccgag
atggttctggccgtcgaccagcgcgtaccggatccggcggccgaagccgacttggtcaag
cgtggttcgatcgagcgtgccttgaagtacatggggctgaccgccaaccaggcgatcacc
gacatcaagttggaccgtgtgttcatcggctcgtgcaccaactcgcgaatcgaggacctg
cgcgctgcggcggaaatcgccaagggtcgcaaggtggccgccagcgtcaagcaagccatc
gtcgtgccgggttcgggcctggtcaaggcccaggccgagcgtgaaggcctggacaagatc
ttcctcgaagccggtttcgaatggcgtgaaccaggctgctcgatgtgcctggcgatgaac
ccggaccgcctggaaagcggcgagcattgcgcgtccacctccaaccgcaacttcgaaggc
cgtcagggcgccggtggccgtacccacctggtcagtccggccatggccgccgctgccgcg
gtagccggccacttcatcgatgtccgcgagttgatccaagggagcgcagcatga
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