Pseudomonas putida DOT-T1E: T1E_1946
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Entry
T1E_1946 CDS
T02181
Symbol
purL
Name
(GenBank) Phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ppx
Pseudomonas putida DOT-T1E
Pathway
ppx00230
Purine metabolism
ppx01100
Metabolic pathways
ppx01110
Biosynthesis of secondary metabolites
Module
ppx_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ppx00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
T1E_1946 (purL)
Enzymes [BR:
ppx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
T1E_1946 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AFO47794
UniProt:
I7C7U6
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Position
complement(2126792..2130691)
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AA seq
1299 aa
AA seq
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MLILRGAPALSAFRHGKLLEQLSQKVPAVTGLYAEFAHFADVDGELTADQQQVLGRLLKY
GPSVPVQEPTGRLFLVVPRLGTISPWASKASDIAHNCGLQSIQRLERGIAYYVAGTLSDA
DAALIAAELHDRMTQRVLSQLEQAADLFSHAQPKPMTSVDILAGGRDALAKANIDLGLAL
AEDEIDYLVNAFQGLKRNPNDIELMMFAQANSEHCRHKIFNASWDIDGQAQEKSLFGMIK
NTYQMHNEGVLSAYKDNASVIVGNVAGRFFPNPETRQYGAVQEPVHILMKVETHNHPTAI
APFSGASTGSGGEIRDEGATGRGAKPKAGLTGFTVSNLRIPGFEQPWEQAYGKPERIVDA
LDIMIEGPLGGAAFNNEFGRPALTGYFRTFEQAINTPHGEEVRGYHKPIMLAGGMGNIRE
DHVQKGEITVGAKLIVLGGPAMLIGLGGGAASSVATGASSADLDFASVQRENPEMERRCQ
EVIDRCWQLGDNNPIAFIHDVGAGGISNAFPELVNDGGRGGRFELRNVPNDEPGMAPHEI
WSNESQERYVLAVSAVDFERFKAICERERCPFAVVGEATEEPHLTVSDSHFGNTPVDMPL
DVLLGKPPRMHRSVTREAELGDDFDPSELDLDSAVQRVLNHPAVASKSFLITIGDRTITG
LVARDQMVGPWQVPVADCAVTATSFDVYTGEAMAMGERTPLALLDAPASGRMAIGETLTN
LAASRIEKLSDIKLSANWMSAAGHPGEDARLYDTVKAVGMELCPELGITIPVGKDSMSMK
TKWSDEGVEKSVTSPMSLIITGFAPVTDIRKTLTPQLRMDKGETDLILIDLGRGKNRMGA
SILAQTYGKIAAQAPDVDDAEDLKAFFAVIQGLNADGHLLAYHDRSDGGLVTTVLEMAFA
GHCGLDLQLDPLTDSKGEVPAILFNEELGAVIQVRQDATPDVLAQFSAAGLGEECVAVIG
KPVNNAEVTISLNGEVLFDDDRRMLQRQWAETSYQIQRLRDNADCADQEFDLLLEEDNPG
LSVKLGFDVNDDIAAPYIKKGVRPQVAILREQGVNGQVEMAAAFDRAGFAAIDVHMSDIL
AGRVDFEAFKGLVACGGFSYGDVLGAGEGWAKSALFNARARDAFQAFFERTDSFALGVCN
GCQMMSNLHELIPGTEYWPHFVRNRSEQFEARVAMVEVQKSNSIFLQGMAGSRMPIAIAH
GEGHAEFASEEALLAADVSGCVALRYVDNHGKVTEAYPANPNGSPRGITGLTSRDGRVTI
MMPHPERVFRAVQNSWRPDEWQEDAALMRMFRNARVWVN
NT seq
3900 nt
NT seq
+upstream
nt +downstream
nt
atgttgatcctgcgcggcgctcctgccctttctgcctttcgccacggtaaattactcgag
caactgagccagaaagtccccgctgttactggtttgtatgccgaatttgcccacttcgcc
gatgttgacggcgagctgaccgccgaccagcagcaggtgctgggccgtctgctcaagtac
ggcccgagcgtgccggtacaggagccgacgggtcgtctgttcctggtggtaccgcgcctg
ggcaccatttcgccatgggccagcaaggccagcgacatcgcccacaactgcggcctgcag
tcgatccagcgcctggagcgcggcatcgcctactacgtggccggcaccctgagcgacgct
gacgccgccctgatcgccgccgaactgcacgaccgcatgacccagcgtgtgctcagccag
ctggagcaggccgctgacctgttcagccacgcccagcccaagccaatgacctcggtcgac
atcctggcaggcggccgtgacgccctggccaaggccaacatcgacctgggcctggccctg
gccgaagacgagatcgactacctggtcaatgccttccagggcctcaagcgcaacccgaac
gacatcgaactgatgatgttcgcccaggccaactccgagcactgccgccacaagatcttc
aacgccagttgggatatcgacggccaggcccaggaaaaaagcctgttcggcatgatcaaa
aacacctaccagatgcacaacgaaggtgtgctgtcggcgtacaaggacaacgcctcggtg
atcgtcggcaacgttgccggccgcttcttcccgaaccctgaaacccgccagtacggcgcg
gtgcaggagccggtgcacatcctgatgaaggtggaaacgcacaaccacccgaccgccatc
gccccgttctccggcgcctccaccggctccggtggcgaaatccgcgacgaaggtgcgacc
ggccgtggcgccaagcccaaggccggcctgaccggcttcaccgtgtccaacctgcgtatc
ccgggcttcgagcagccgtgggagcaggcttatggcaagcccgagcgtatcgtcgacgcc
ctcgacatcatgatcgaaggccctcttggcggcgctgcgttcaacaacgaattcggccgc
ccggccctgaccggttacttccgtaccttcgagcaagccatcaacaccccgcacggtgaa
gaagtgcgcggctaccacaagccgatcatgctcgccggcggtatgggcaacatccgtgaa
gaccacgtgcagaagggcgaaatcactgtcggcgccaagctgatcgtgctcggtggcccg
gccatgctgatcggcctgggcggcggcgctgcttcgtcggtggctaccggtgccagctcg
gctgacctggatttcgcttcggtacagcgcgaaaacccggaaatggagcgccgttgccag
gaggtcatcgaccgttgctggcagctgggcgacaacaacccgatcgccttcatccacgac
gtgggcgctggcggtatttccaacgccttccctgagctggtcaacgacggtggccgcggt
ggccgcttcgagctgcgcaacgtgcccaacgacgagccgggcatggccccgcacgaaatc
tggagcaacgaatcgcaagagcgttacgtgctggccgtcagcgcggtcgacttcgagcgc
ttcaaggccatctgcgagcgcgagcgttgcccgtttgccgtggtcggtgaagccactgaa
gaaccgcacctgaccgtcagcgacagccacttcggcaacaccccggtggacatgccgctg
gacgtgctgctgggcaagccgccgcgcatgcaccgttcggttacccgcgaagccgagctg
ggcgatgacttcgacccgagcgagctggacctggacagcgccgtccagcgcgtgctgaac
cacccggccgtggccagcaagagcttcctgatcaccattggcgaccgcaccatcaccggc
ctggttgcccgcgaccagatggtcggcccgtggcaggttccggtggctgactgcgccgtt
accgccaccagcttcgacgtctacaccggtgaagccatggccatgggcgagcgtacgccg
ctggcgctgctggatgccccggcgtccggccgcatggccatcggcgaaaccctgaccaac
ctggcggcttcgcgcatcgaaaagctgtccgacatcaaactgtcggccaactggatgtcc
gctgctggtcacccaggtgaagacgcacgtctgtacgacaccgtgaaggctgtcggcatg
gagctgtgcccggagttgggcatcaccattccggtcggcaaagactcgatgtcgatgaag
accaagtggagcgacgagggcgtcgagaagagcgtcacctcgccgatgtcgctgatcatc
accggcttcgccccggtcaccgacatccgtaagaccctgaccccgcaactgcgcatggac
aagggcgagaccgacctgatcctgatcgacctgggccgcggcaagaaccgcatgggcgcc
tcgatcctggcccagacctacggcaagatcgctgcccaggcaccggacgtcgacgacgcc
gaagacctcaaggccttcttcgccgtgatccagggcctgaacgccgacggccacctgctg
gcctaccacgaccgttccgacggcggcctggttaccaccgtgctggaaatggccttcgcc
ggccactgcggcctcgacctacaactcgacccgctgaccgacagcaagggcgaagtgccg
gccatcctcttcaacgaagagctgggtgcggtgatccaggttcgccaggatgctaccccg
gacgtgctggctcagttcagcgctgctggcctgggtgaagagtgcgtcgcggtgatcggc
aagccagtcaacaacgctgaagtgaccatcagcctgaacggcgaagtgctgttcgacgat
gaccgtcgcatgctgcagcgccagtgggctgaaaccagctaccagatccagcgcctgcgc
gacaacgccgactgcgctgaccaggagttcgacctgctgctcgaggaagacaacccgggt
ctgtcggtgaagctgggcttcgacgtcaacgacgacatcgcggcgccttacatcaagaaa
ggcgtgcgcccgcaagtggccatcctgcgcgagcagggtgtcaacggccaggtcgagatg
gctgctgccttcgaccgcgccggcttcgccgccatcgacgtgcacatgagcgatattctc
gctggccgtgtcgacttcgaagccttcaagggcctggtcgcctgtggcggcttctcgtac
ggtgacgtgctgggcgctggcgaaggctgggccaagtcggcgctgttcaacgcccgtgcc
cgtgacgccttccaggccttcttcgagcgtaccgacagcttcgccctgggcgtgtgcaac
ggttgccagatgatgtccaacctgcacgagctgatcccgggcaccgagtactggccgcac
ttcgtgcgcaaccgctcggagcagttcgaggcacgcgtggccatggtcgaagtgcagaag
tccaactcgatcttcctgcagggcatggccggttcgcgcatgccgatcgccatcgcccac
ggcgaaggccatgccgagttcgccagcgaagaagcactgctggccgctgacgtatccggt
tgcgtggccctgcgctacgtcgacaaccacggcaaggtcaccgaagcctacccggccaac
ccgaacggctcgccgcgtggtatcaccggcctgaccagccgcgacggccgcgtgaccatc
atgatgccgcacccggagcgtgtgttccgcgctgtgcaaaactcctggcgcccggacgag
tggcaggaagatgccgcgctgatgcgtatgttccgcaacgcgcgggtgtgggtgaactaa
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