Pseudomonas putida DOT-T1E: T1E_5099
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Entry
T1E_5099 CDS
T02181
Symbol
bkdA1
Name
(GenBank) 2-oxoisovalerate dehydrogenase subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
ppx
Pseudomonas putida DOT-T1E
Pathway
ppx00280
Valine, leucine and isoleucine degradation
ppx00640
Propanoate metabolism
ppx00785
Lipoic acid metabolism
ppx01100
Metabolic pathways
ppx01110
Biosynthesis of secondary metabolites
ppx01210
2-Oxocarboxylic acid metabolism
Module
ppx_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ppx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
T1E_5099 (bkdA1)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
T1E_5099 (bkdA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
T1E_5099 (bkdA1)
Enzymes [BR:
ppx01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
T1E_5099 (bkdA1)
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GFIT
Motif
Pfam:
E1_dh
OxoDH_E1alpha_N
TPP_enzyme_C
DUF3560
DXP_synthase_N
LutB_C
Motif
Other DBs
NCBI-ProteinID:
AFO50923
UniProt:
I7BGL7
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All DBs
Position
5542759..5543991
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AA seq
410 aa
AA seq
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MNEYAPLRLHVPEPTGRPGCQTDFSYLRLNDAGQARKPAIDVDAADTADLSYSLVRVLDE
QGDAQGPWAEDIDPQILRQGMRAMLKTRIFDSRMVVAQRQKKMSFYMQSLGEEAIGSGQA
LALNRTDMCFPTYRQQSILMARDVSLVEMICQLLSNERDPLKGRQLPIMYSVREAGFFTI
SGNLATQFVQAVGWAMASAIKGDTKIASAWIGDGATAESDFHTALTFAHVYRAPVILNVV
NNQWAISTFQAIAGGESTTFAGRGVGCGIASLRVDGNDFVAVYAASRWAAERARRGLGPS
LIEWVTYRAGPHSTSDDPSKYRPADDWSHFPLGDPIARLKQHLIKIGHWSEEEHQAVTAE
LEAAVIAAQKEAEQYGTLANGHIPSAASMFEDVYKEMPEHLRRQRQELGV
NT seq
1233 nt
NT seq
+upstream
nt +downstream
nt
atgaacgagtacgcccccctgcgtttgcatgtgcccgagcccaccggccggccaggctgc
cagaccgatttttcctacctgcgcctcaacgatgcaggtcaagcccgtaaacccgcgatc
gatgtcgatgctgccgacactgccgacctgtcctacagcctggtccgcgtgctcgacgag
caaggcgacgcgcaaggcccctgggccgaagacattgacccgcagatccttcgtcaaggc
atgcgcgccatgctcaagacgcggatcttcgacagccgcatggtggttgcccagcgccag
aagaagatgtccttctacatgcaaagcctgggcgaagaagccatcggcagcggccaggcg
ctggcgctgaaccgcaccgacatgtgcttcccgacctaccgccagcaaagcatcctgatg
gcccgcgacgtgtcgctggtcgagatgatctgccaactgctgtccaacgagcgcgacccc
ctcaagggccgccagttgccgatcatgtactcggtgcgcgaagccggcttcttcaccatc
agcggcaacctggcgacccagttcgtgcaggcggtcggctgggccatggcatcggcgatc
aagggcgataccaagatcgcctcggcgtggatcggtgacggcgctactgccgagtcagac
ttccacaccgcccttacctttgcccacgtataccgcgccccggtcatcctcaacgtggtc
aacaaccagtgggccatttccaccttccaggccatcgccggtggcgagtcgaccaccttt
gccggccgtggcgtgggttgcggtattgcttcgctgcgggttgacggcaacgacttcgtc
gccgtgtacgccgcctcgcgctgggctgccgagcgcgcccgccgcggcctgggcccaagc
ctgatcgagtgggtcacctaccgtgccggcccgcactcgacgtcggacgacccctccaag
taccgccctgccgatgactggagccacttcccgctgggtgacccgatcgcccgcctgaag
cagcacctgatcaagatcggccactggtccgaagaagaacaccaggccgtcacggccgag
ctcgaagctgcggtgattgccgcacagaaagaagccgagcagtacggcaccctggctaac
gggcacatcccgagcgccgcctcgatgttcgaggatgtgtacaaggagatgcccgaacac
ctgcgccgtcaacgccaggaactgggggtttga
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