KEGG   Pongo pygmaeus (Bornean orangutan): 129007179
Entry
129007179         CDS       T10128                                 
Symbol
HRAS
Name
(RefSeq) GTPase HRas isoform X1
  KO
K02833  GTPase HRas
Organism
ppyg  Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg01521  EGFR tyrosine kinase inhibitor resistance
ppyg01522  Endocrine resistance
ppyg04010  MAPK signaling pathway
ppyg04012  ErbB signaling pathway
ppyg04014  Ras signaling pathway
ppyg04015  Rap1 signaling pathway
ppyg04062  Chemokine signaling pathway
ppyg04068  FoxO signaling pathway
ppyg04071  Sphingolipid signaling pathway
ppyg04072  Phospholipase D signaling pathway
ppyg04137  Mitophagy - animal
ppyg04140  Autophagy - animal
ppyg04144  Endocytosis
ppyg04150  mTOR signaling pathway
ppyg04151  PI3K-Akt signaling pathway
ppyg04210  Apoptosis
ppyg04211  Longevity regulating pathway
ppyg04213  Longevity regulating pathway - multiple species
ppyg04218  Cellular senescence
ppyg04360  Axon guidance
ppyg04370  VEGF signaling pathway
ppyg04371  Apelin signaling pathway
ppyg04510  Focal adhesion
ppyg04540  Gap junction
ppyg04550  Signaling pathways regulating pluripotency of stem cells
ppyg04625  C-type lectin receptor signaling pathway
ppyg04630  JAK-STAT signaling pathway
ppyg04650  Natural killer cell mediated cytotoxicity
ppyg04660  T cell receptor signaling pathway
ppyg04662  B cell receptor signaling pathway
ppyg04664  Fc epsilon RI signaling pathway
ppyg04714  Thermogenesis
ppyg04720  Long-term potentiation
ppyg04722  Neurotrophin signaling pathway
ppyg04725  Cholinergic synapse
ppyg04726  Serotonergic synapse
ppyg04730  Long-term depression
ppyg04810  Regulation of actin cytoskeleton
ppyg04910  Insulin signaling pathway
ppyg04912  GnRH signaling pathway
ppyg04915  Estrogen signaling pathway
ppyg04916  Melanogenesis
ppyg04917  Prolactin signaling pathway
ppyg04919  Thyroid hormone signaling pathway
ppyg04921  Oxytocin signaling pathway
ppyg04926  Relaxin signaling pathway
ppyg04929  GnRH secretion
ppyg04933  AGE-RAGE signaling pathway in diabetic complications
ppyg04935  Growth hormone synthesis, secretion and action
ppyg05010  Alzheimer disease
ppyg05022  Pathways of neurodegeneration - multiple diseases
ppyg05034  Alcoholism
ppyg05132  Salmonella infection
ppyg05160  Hepatitis C
ppyg05161  Hepatitis B
ppyg05163  Human cytomegalovirus infection
ppyg05165  Human papillomavirus infection
ppyg05166  Human T-cell leukemia virus 1 infection
ppyg05167  Kaposi sarcoma-associated herpesvirus infection
ppyg05170  Human immunodeficiency virus 1 infection
ppyg05200  Pathways in cancer
ppyg05203  Viral carcinogenesis
ppyg05205  Proteoglycans in cancer
ppyg05206  MicroRNAs in cancer
ppyg05207  Chemical carcinogenesis - receptor activation
ppyg05208  Chemical carcinogenesis - reactive oxygen species
ppyg05210  Colorectal cancer
ppyg05211  Renal cell carcinoma
ppyg05213  Endometrial cancer
ppyg05214  Glioma
ppyg05215  Prostate cancer
ppyg05216  Thyroid cancer
ppyg05218  Melanoma
ppyg05219  Bladder cancer
ppyg05220  Chronic myeloid leukemia
ppyg05221  Acute myeloid leukemia
ppyg05223  Non-small cell lung cancer
ppyg05224  Breast cancer
ppyg05225  Hepatocellular carcinoma
ppyg05226  Gastric cancer
ppyg05230  Central carbon metabolism in cancer
ppyg05231  Choline metabolism in cancer
ppyg05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ppyg05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ppyg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    129007179 (HRAS)
   04012 ErbB signaling pathway
    129007179 (HRAS)
   04014 Ras signaling pathway
    129007179 (HRAS)
   04015 Rap1 signaling pathway
    129007179 (HRAS)
   04370 VEGF signaling pathway
    129007179 (HRAS)
   04371 Apelin signaling pathway
    129007179 (HRAS)
   04630 JAK-STAT signaling pathway
    129007179 (HRAS)
   04068 FoxO signaling pathway
    129007179 (HRAS)
   04072 Phospholipase D signaling pathway
    129007179 (HRAS)
   04071 Sphingolipid signaling pathway
    129007179 (HRAS)
   04151 PI3K-Akt signaling pathway
    129007179 (HRAS)
   04150 mTOR signaling pathway
    129007179 (HRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    129007179 (HRAS)
   04140 Autophagy - animal
    129007179 (HRAS)
   04137 Mitophagy - animal
    129007179 (HRAS)
  09143 Cell growth and death
   04210 Apoptosis
    129007179 (HRAS)
   04218 Cellular senescence
    129007179 (HRAS)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    129007179 (HRAS)
   04540 Gap junction
    129007179 (HRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    129007179 (HRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    129007179 (HRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    129007179 (HRAS)
   04650 Natural killer cell mediated cytotoxicity
    129007179 (HRAS)
   04660 T cell receptor signaling pathway
    129007179 (HRAS)
   04662 B cell receptor signaling pathway
    129007179 (HRAS)
   04664 Fc epsilon RI signaling pathway
    129007179 (HRAS)
   04062 Chemokine signaling pathway
    129007179 (HRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    129007179 (HRAS)
   04929 GnRH secretion
    129007179 (HRAS)
   04912 GnRH signaling pathway
    129007179 (HRAS)
   04915 Estrogen signaling pathway
    129007179 (HRAS)
   04917 Prolactin signaling pathway
    129007179 (HRAS)
   04921 Oxytocin signaling pathway
    129007179 (HRAS)
   04926 Relaxin signaling pathway
    129007179 (HRAS)
   04935 Growth hormone synthesis, secretion and action
    129007179 (HRAS)
   04919 Thyroid hormone signaling pathway
    129007179 (HRAS)
   04916 Melanogenesis
    129007179 (HRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    129007179 (HRAS)
   04726 Serotonergic synapse
    129007179 (HRAS)
   04720 Long-term potentiation
    129007179 (HRAS)
   04730 Long-term depression
    129007179 (HRAS)
   04722 Neurotrophin signaling pathway
    129007179 (HRAS)
  09158 Development and regeneration
   04360 Axon guidance
    129007179 (HRAS)
  09149 Aging
   04211 Longevity regulating pathway
    129007179 (HRAS)
   04213 Longevity regulating pathway - multiple species
    129007179 (HRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    129007179 (HRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129007179 (HRAS)
   05206 MicroRNAs in cancer
    129007179 (HRAS)
   05205 Proteoglycans in cancer
    129007179 (HRAS)
   05207 Chemical carcinogenesis - receptor activation
    129007179 (HRAS)
   05208 Chemical carcinogenesis - reactive oxygen species
    129007179 (HRAS)
   05203 Viral carcinogenesis
    129007179 (HRAS)
   05230 Central carbon metabolism in cancer
    129007179 (HRAS)
   05231 Choline metabolism in cancer
    129007179 (HRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    129007179 (HRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    129007179 (HRAS)
   05225 Hepatocellular carcinoma
    129007179 (HRAS)
   05226 Gastric cancer
    129007179 (HRAS)
   05214 Glioma
    129007179 (HRAS)
   05216 Thyroid cancer
    129007179 (HRAS)
   05221 Acute myeloid leukemia
    129007179 (HRAS)
   05220 Chronic myeloid leukemia
    129007179 (HRAS)
   05218 Melanoma
    129007179 (HRAS)
   05211 Renal cell carcinoma
    129007179 (HRAS)
   05219 Bladder cancer
    129007179 (HRAS)
   05215 Prostate cancer
    129007179 (HRAS)
   05213 Endometrial cancer
    129007179 (HRAS)
   05224 Breast cancer
    129007179 (HRAS)
   05223 Non-small cell lung cancer
    129007179 (HRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    129007179 (HRAS)
   05170 Human immunodeficiency virus 1 infection
    129007179 (HRAS)
   05161 Hepatitis B
    129007179 (HRAS)
   05160 Hepatitis C
    129007179 (HRAS)
   05163 Human cytomegalovirus infection
    129007179 (HRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    129007179 (HRAS)
   05165 Human papillomavirus infection
    129007179 (HRAS)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    129007179 (HRAS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    129007179 (HRAS)
   05022 Pathways of neurodegeneration - multiple diseases
    129007179 (HRAS)
  09165 Substance dependence
   05034 Alcoholism
    129007179 (HRAS)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    129007179 (HRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    129007179 (HRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    129007179 (HRAS)
   01522 Endocrine resistance
    129007179 (HRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ppyg04131]
    129007179 (HRAS)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ppyg04147]
    129007179 (HRAS)
   04031 GTP-binding proteins [BR:ppyg04031]
    129007179 (HRAS)
Membrane trafficking [BR:ppyg04131]
 Exocytosis
  Small GTPases and associated proteins
   Other small GTPases and associated proteins
    129007179 (HRAS)
 Endocytosis
  Macropinocytosis
   Ras GTPases
    129007179 (HRAS)
Exosome [BR:ppyg04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   129007179 (HRAS)
  Exosomal proteins of colorectal cancer cells
   129007179 (HRAS)
GTP-binding proteins [BR:ppyg04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    129007179 (HRAS)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase FeoB_N ATP_bind_1 Septin Ldh_1_N AAA_16
Other DBs
NCBI-GeneID: 129007179
NCBI-ProteinID: XP_054293646
LinkDB
Position
9:complement(428731..432104)
AA seq 189 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL
AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPG
CMSCKCVLS
NT seq 570 nt   +upstreamnt  +downstreamnt
atgacggaatataagctcgtggtggtgggcgccggcggtgtgggcaagagtgcgctgacc
atccagctgatccagaaccactttgtggacgaatacgaccccactatagaggactcctat
cggaagcaggtggtcattgatggggagacatgcctgttggacatcctggacacggctggc
caggaggagtacagcgccatgcgggaccagtacatgcgcactggggagggcttcctgtgt
gtgtttgccatcaacaacaccaagtctttcgaggacatccaccagtacagggagcagatc
aagcgggtgaaggactcggacgacgtgcccatggtgctggtggggaacaagtgtgacctg
gctgcacgcaccgtggagtctcggcaggctcaagacctcgcccgaagctacggcatcccc
tacatcgagacctcggccaagacccggcagggagtggaggatgccttctacacgttggtg
cgtgagatccggcagcacaagctgcggaagctgaaccctcctgatgagagtggccccggc
tgcatgagctgcaagtgtgtgctctcctga

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