Pongo pygmaeus (Bornean orangutan): 129010490
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Entry
129010490 CDS
T10128
Symbol
NOS1
Name
(RefSeq) nitric oxide synthase 1 isoform X1
KO
K13240
nitric-oxide synthase, brain [EC:
1.14.13.39
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg00220
Arginine biosynthesis
ppyg00330
Arginine and proline metabolism
ppyg01100
Metabolic pathways
ppyg04020
Calcium signaling pathway
ppyg04081
Hormone signaling
ppyg04145
Phagosome
ppyg04371
Apelin signaling pathway
ppyg04713
Circadian entrainment
ppyg04730
Long-term depression
ppyg04926
Relaxin signaling pathway
ppyg04970
Salivary secretion
ppyg05010
Alzheimer disease
ppyg05014
Amyotrophic lateral sclerosis
ppyg05022
Pathways of neurodegeneration - multiple diseases
ppyg05410
Hypertrophic cardiomyopathy
ppyg05412
Arrhythmogenic right ventricular cardiomyopathy
ppyg05414
Dilated cardiomyopathy
ppyg05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
129010490 (NOS1)
00330 Arginine and proline metabolism
129010490 (NOS1)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
129010490 (NOS1)
04020 Calcium signaling pathway
129010490 (NOS1)
09133 Signaling molecules and interaction
04081 Hormone signaling
129010490 (NOS1)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
129010490 (NOS1)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
129010490 (NOS1)
09154 Digestive system
04970 Salivary secretion
129010490 (NOS1)
09156 Nervous system
04730 Long-term depression
129010490 (NOS1)
09159 Environmental adaptation
04713 Circadian entrainment
129010490 (NOS1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
129010490 (NOS1)
05014 Amyotrophic lateral sclerosis
129010490 (NOS1)
05022 Pathways of neurodegeneration - multiple diseases
129010490 (NOS1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
129010490 (NOS1)
05412 Arrhythmogenic right ventricular cardiomyopathy
129010490 (NOS1)
05414 Dilated cardiomyopathy
129010490 (NOS1)
05416 Viral myocarditis
129010490 (NOS1)
Enzymes [BR:
ppyg01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
129010490 (NOS1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
PDZ
PDZ_6
PDZ_2
Motif
Other DBs
NCBI-GeneID:
129010490
NCBI-ProteinID:
XP_054300737
LinkDB
All DBs
Position
10:complement(115920382..116131382)
Genome browser
AA seq
1468 aa
AA seq
DB search
MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
RVTQPLGPPTKAVDLSHQPLAGKEQPLAVDGASAPGNGPQHAYDDGQEAGSLPHANGLAP
RPPGQDPAKKATRVGLQGRGENNELLKEIEPVLSLLTSGSRGVKGGAPAKAEMKDMGIQV
DRDLDGKSHKPLPLSVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPASGKQSPTKNGSPS
KCPRFLKVKNWETDVVLTDTLHLKSTLETGCTEYICMGSIMLPSQHTRRPEDVRTREQLF
PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIETTSTYQLKDTELIYGAKHAWRNASRC
VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW
NSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ
IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ
EERKYPEPLRFFPRKGPPLPSGDTEVHGLAAARDSQHRSYKVRFNSVSSYSDSQKSSGDG
PDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC
GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTFVAEAPELT
QGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGNQELQYQPGDHLGVFPGNHE
DLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTDEHRLPPCTIFQAFKYYLDIT
TPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPAT
LLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQAD
EVVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCPMVLVF
GCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAESVYQALKE
QGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRMRDDNRYHEDIFGVTLRT
YEVTNRLRSESIAFIEESKKDTDEVFSS
NT seq
4407 nt
NT seq
+upstream
nt +downstream
nt
atggaggatcacatgttcggtgttcagcaaatccagcccaatgtcatttctgttcgtctc
ttcaagcgcaaagttgggggcctgggattcctggtgaaggagcgggtcagtaagccgccc
gtgatcatctctgacctgattcgtgggggtgccgcggagcagagtggcctcatccaggct
ggagacatcattcttgcggtcaacggccggcccttggtggacctgagctatgatagcgcc
ctggaggtactcagaggcattgcctccgagacccacgtggtcctcattctgaggggccct
gaaggtttcaccacgcacctggagaccacctttacaggtgacgggacccccaagaccatc
cgggtgacacagcccctgggtccccccaccaaagccgtggatctgtcccaccagccattg
gctggcaaagaacagcccctggcagtggatggggcctcggctcccgggaatgggcctcag
catgcctacgatgatgggcaggaagctggctcgctcccccatgccaacggcctggccccg
aggcccccaggccaggaccctgcgaagaaagcaaccagagtcggcctccaaggcagaggg
gagaacaatgaactgctcaaggagatagagcctgtgctgagccttctcaccagtgggagc
agaggggtaaagggaggggcacctgccaaggcagagatgaaagatatgggaatccaggtg
gacagagatttggacggcaagtcacacaaacctctgcccctcagcgtggagaacgaccga
gtcttcaatgacctatgggggaagggcaatgtgcctgtcgtcctcaacaacccatattca
gagaaggagcagccccctgcctcaggaaaacagtcccccacaaagaatggcagcccctcc
aagtgtccacgcttcctcaaggtcaagaactgggagactgacgtggttctcactgacacc
ctccaccttaagagcacattggaaacaggatgcactgagtacatctgcatgggctccatc
atgcttccttctcagcatacacggaggcctgaagacgtccgcaccagagaacagctcttc
cctcttgccaaagagtttattgatcaatactattcatcaattaaaagatttggctccaaa
gcccacatggaaaggctggaagaggtgaacaaagagattgaaaccactagcacctaccag
ctcaaggacacagagctcatctatggggccaagcatgcctggcggaatgcctcgcgctgt
gtgggcaggatccagtggtccaagctgcaggtattcgatgcccgcgactgcaccacggcc
cacgggatgttcaactacatctgtaaccacgtcaagtatgccaccaacaaagggaacctg
aggtctgccatcaccatattcccccagaggacagacggcaagcacgacttcagagtctgg
aactcccagctcatccgctacgctggctacaagcagcccgacggctccaccctgggggac
ccggccaacgtgcagttcacagagatttgcatacagcagggctggaaaccaccgagaggc
cgcttcgatgtcctgccgctcctgcttcaggccaacggcaatgaccctgagctcttccag
attcctccagagctggtgttggaagttcccatcaggcaccccaagtttgagtggttcaag
gacctggggctgaagtggtacggcctccccgccgtgtccaacatgctcctggagattggt
ggcctggagttcagcgcctgtcccttcagtggctggtacatgggcacagagattggtgtc
cgcgactactgtgacaactcccgctacaatatcctggaggaagtggccaagaagatgaac
ttagacatgaggaagacgtcctccctgtggaaggaccaggcgctggtggagatcaatatc
gccgttctctacagcttccagagtgacaaagtgaccattgttgaccatcactccgccacc
gagtccttcattaagcacatggagaatgagtaccgctgccgggggggctgccctgccgac
tgggtgtggatcgtgccccccatgtccggaagcatcacccctgtgttccaccaggagatg
ctcaactaccggctcaccccctccttcgaataccagcctgatccctggaacacccatgtc
tggaaaggcaccaatgggacccccacaaagaggcgagccatcggcttcaagaagctagca
gaagctgtcaagttctcagccaagctgatggggcaggctatggccaagagggtcaaagcg
accatcctctatgccacggagacaggcaaatcgcaagcttatgccaagaccttgtgtgag
atcttcaaacacgcctttgatgccaaggtgatgtccatggaggaatatgacatcgtgcac
ctggaacatgaaactctggtcctcgtggttaccagcaccttcggcaacggagatccccct
gagaatggggagaaattcggctgtgctttgatggaaatgaggcaccccaactctgtgcag
gaagaaaggaagtacccggaacccttgcgtttctttcctcgtaaagggcctcccctcccc
agtggtgacacagaagtccacggtctggctgcagcccgtgacagccagcacaggagctac
aaggtccgattcaacagcgtctcctcctactctgactcccaaaaatcatcaggcgatggg
cccgacctcagagacaactttgagagtgctggacccctggccaatgtgaggttctcagtt
tttggcctcggctcacgagcataccctcacttttgcgccttcggacatgctgtggacacc
ctcctggaagaactgggaggggagaggatcctgaagatgagggaaggggatgagctctgt
gggcaggaggaggctttcaggacctgggccaagaaggtcttcaaggcagcctgtgatgtc
ttctgtgtgggagatgatgtcaacattgaaaaggcgaacaattccctcatcagcaatgac
cgcagctggaagagaaacaagttccgcctcacctttgtggccgaagctccagaactcaca
caaggtctatccaatgtccacaaaaagcgagtctcagctgcccggctccttagccgtcaa
aacctccagagccctaaatcaagtcggtcaactatcttcgtgcgtctccacaccaacggg
aaccaggagctgcagtaccagcctggggaccacctgggtgtcttccctggcaaccacgag
gacctcgtgaatgccctgatcgagcggctggaggacgcgccccctgtcaaccagatggta
aaagtggaattgctggaggagcggaacacggctttaggtgtcatcagtaactggacagac
gagcaccgcctcccgccctgcaccatcttccaggccttcaagtactacctggacatcacc
acgccgccaacgcccctgcagctgcagcagtttgcctccctagccaccagcgagaaggag
aagcagcgtctgctggtcctcagcaagggtttgcaggagtacgaggaatggaaatggggc
aagaaccccaccatcgtggaggtgctggaggagttcccatctatccagatgccagccacc
ctgctcctgacccagctgtccctgctgcagccccgctactattccatcagctcctcccca
gacatgtaccctgatgaagtgcacctcactgtggccatcgtttcctaccgcactcgagat
ggagaaggaccaattcaccacggcgtgtgctcctcctggctcaaccggatacaggctgac
gaagtggtcccctgtttcgtgagaggagcacccagcttccacctgccccggaacccccaa
gtcccctgcatcctcgttggaccgggcaccggcattgcccctttccgaagcttctggcaa
cagcggcaatttgatatccaacacaaaggaatgaacccctgccccatggtcctggtcttc
gggtgccggcaatccaagatagatcatatctacagggaagagaccctgcaggccaagaac
aagggggtcttcagagagctgtacacggcttactcccgggagccagacaaaccaaagaag
tacgtgcaggacatcctgcaggagcagctggcggagtctgtgtaccaagccctgaaggag
caagggggccacatttacgtctgtggggacgtcaccatggctgctgatgtcctcaaagcc
atccagcgcatcatgacccagcaggggaagctctcggcagaggatgccggcgtgttcatc
agccggatgagggatgacaaccgataccatgaggatatattcggagtcaccctgcgaacg
tatgaagtgaccaaccgccttagatctgagtccattgccttcattgaagagagcaaaaaa
gacaccgatgaggttttcagctcctaa
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integrated database retrieval system
