KEGG   Pongo pygmaeus (Bornean orangutan): 129010938
Entry
129010938         CDS       T10128                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X1
  KO
K05459  insulin-like growth factor 1
Organism
ppyg  Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg01521  EGFR tyrosine kinase inhibitor resistance
ppyg01522  Endocrine resistance
ppyg04010  MAPK signaling pathway
ppyg04014  Ras signaling pathway
ppyg04015  Rap1 signaling pathway
ppyg04066  HIF-1 signaling pathway
ppyg04068  FoxO signaling pathway
ppyg04081  Hormone signaling
ppyg04114  Oocyte meiosis
ppyg04115  p53 signaling pathway
ppyg04150  mTOR signaling pathway
ppyg04151  PI3K-Akt signaling pathway
ppyg04152  AMPK signaling pathway
ppyg04211  Longevity regulating pathway
ppyg04213  Longevity regulating pathway - multiple species
ppyg04510  Focal adhesion
ppyg04550  Signaling pathways regulating pluripotency of stem cells
ppyg04730  Long-term depression
ppyg04750  Inflammatory mediator regulation of TRP channels
ppyg04913  Ovarian steroidogenesis
ppyg04914  Progesterone-mediated oocyte maturation
ppyg04935  Growth hormone synthesis, secretion and action
ppyg04960  Aldosterone-regulated sodium reabsorption
ppyg05200  Pathways in cancer
ppyg05202  Transcriptional misregulation in cancer
ppyg05205  Proteoglycans in cancer
ppyg05214  Glioma
ppyg05215  Prostate cancer
ppyg05218  Melanoma
ppyg05224  Breast cancer
ppyg05410  Hypertrophic cardiomyopathy
ppyg05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ppyg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    129010938 (IGF1)
   04014 Ras signaling pathway
    129010938 (IGF1)
   04015 Rap1 signaling pathway
    129010938 (IGF1)
   04066 HIF-1 signaling pathway
    129010938 (IGF1)
   04068 FoxO signaling pathway
    129010938 (IGF1)
   04151 PI3K-Akt signaling pathway
    129010938 (IGF1)
   04152 AMPK signaling pathway
    129010938 (IGF1)
   04150 mTOR signaling pathway
    129010938 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    129010938 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    129010938 (IGF1)
   04115 p53 signaling pathway
    129010938 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    129010938 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    129010938 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    129010938 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    129010938 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    129010938 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    129010938 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    129010938 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    129010938 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    129010938 (IGF1)
   04213 Longevity regulating pathway - multiple species
    129010938 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129010938 (IGF1)
   05202 Transcriptional misregulation in cancer
    129010938 (IGF1)
   05205 Proteoglycans in cancer
    129010938 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    129010938 (IGF1)
   05218 Melanoma
    129010938 (IGF1)
   05215 Prostate cancer
    129010938 (IGF1)
   05224 Breast cancer
    129010938 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    129010938 (IGF1)
   05414 Dilated cardiomyopathy
    129010938 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    129010938 (IGF1)
   01522 Endocrine resistance
    129010938 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ppyg04052]
    129010938 (IGF1)
Cytokines and neuropeptides [BR:ppyg04052]
 Cytokines
  Growth factors (RTK binding)
   129010938 (IGF1)
SSDB
Motif
Pfam: Insulin
Other DBs
NCBI-GeneID: 129010938
NCBI-ProteinID: XP_054301659
LinkDB
Position
10:complement(100912931..100995901)
AA seq 196 aa
MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
VRAQRHTDMPKTQKYQPPSTNKNTKSQRRRKGGPKTHPGGEQKEGTEASLQIRGKKKEQR
REIGSRNAECRGKKGK
NT seq 591 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aaggtgaagatgcacaccatgtcctcctcgcatctcttctacctggcgctgtgcctgctc
accttcaccagctctgccacggctggaccggagacgctctgcggggctgagctggtggat
gctcttcagttcgtgtgtggagacaggggcttttatttcaacaagcccacagggtatggc
tccagcagtcggagggcgcctcagacaggcatcgtggatgagtgctgcttccggagctgt
gatctgaggaggctggagatgtattgtgcacccctcaagcctgccaaatcagcccgctct
gtccgtgcccagcgccacaccgacatgcccaagacccagaagtatcagcccccatctacc
aacaagaacacgaagtctcagaggagaaggaaaggtgggccaaagacacatccaggaggg
gaacagaaggaggggacagaagcaagtctgcagatcagaggaaagaagaaagagcagagg
agggagattggaagtagaaatgctgaatgcagaggcaaaaaaggaaaatga

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