Pongo pygmaeus (Bornean orangutan): 129012612
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Entry
129012612 CDS
T10128
Symbol
ADCY4
Name
(RefSeq) adenylate cyclase type 4 isoform X1
KO
K08044
adenylate cyclase 4 [EC:
4.6.1.1
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg00230
Purine metabolism
ppyg01100
Metabolic pathways
ppyg01522
Endocrine resistance
ppyg04015
Rap1 signaling pathway
ppyg04020
Calcium signaling pathway
ppyg04022
cGMP-PKG signaling pathway
ppyg04024
cAMP signaling pathway
ppyg04062
Chemokine signaling pathway
ppyg04072
Phospholipase D signaling pathway
ppyg04081
Hormone signaling
ppyg04082
Neuroactive ligand signaling
ppyg04114
Oocyte meiosis
ppyg04211
Longevity regulating pathway
ppyg04213
Longevity regulating pathway - multiple species
ppyg04261
Adrenergic signaling in cardiomyocytes
ppyg04270
Vascular smooth muscle contraction
ppyg04371
Apelin signaling pathway
ppyg04540
Gap junction
ppyg04611
Platelet activation
ppyg04713
Circadian entrainment
ppyg04714
Thermogenesis
ppyg04723
Retrograde endocannabinoid signaling
ppyg04724
Glutamatergic synapse
ppyg04725
Cholinergic synapse
ppyg04727
GABAergic synapse
ppyg04742
Taste transduction
ppyg04750
Inflammatory mediator regulation of TRP channels
ppyg04911
Insulin secretion
ppyg04912
GnRH signaling pathway
ppyg04913
Ovarian steroidogenesis
ppyg04914
Progesterone-mediated oocyte maturation
ppyg04915
Estrogen signaling pathway
ppyg04916
Melanogenesis
ppyg04918
Thyroid hormone synthesis
ppyg04921
Oxytocin signaling pathway
ppyg04923
Regulation of lipolysis in adipocytes
ppyg04925
Aldosterone synthesis and secretion
ppyg04926
Relaxin signaling pathway
ppyg04927
Cortisol synthesis and secretion
ppyg04928
Parathyroid hormone synthesis, secretion and action
ppyg04934
Cushing syndrome
ppyg04935
Growth hormone synthesis, secretion and action
ppyg04970
Salivary secretion
ppyg04971
Gastric acid secretion
ppyg04972
Pancreatic secretion
ppyg04976
Bile secretion
ppyg05032
Morphine addiction
ppyg05163
Human cytomegalovirus infection
ppyg05166
Human T-cell leukemia virus 1 infection
ppyg05200
Pathways in cancer
ppyg05207
Chemical carcinogenesis - receptor activation
ppyg05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
129012612 (ADCY4)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
129012612 (ADCY4)
04371 Apelin signaling pathway
129012612 (ADCY4)
04020 Calcium signaling pathway
129012612 (ADCY4)
04072 Phospholipase D signaling pathway
129012612 (ADCY4)
04024 cAMP signaling pathway
129012612 (ADCY4)
04022 cGMP-PKG signaling pathway
129012612 (ADCY4)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
129012612 (ADCY4)
04081 Hormone signaling
129012612 (ADCY4)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
129012612 (ADCY4)
09144 Cellular community - eukaryotes
04540 Gap junction
129012612 (ADCY4)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
129012612 (ADCY4)
04062 Chemokine signaling pathway
129012612 (ADCY4)
09152 Endocrine system
04911 Insulin secretion
129012612 (ADCY4)
04923 Regulation of lipolysis in adipocytes
129012612 (ADCY4)
04912 GnRH signaling pathway
129012612 (ADCY4)
04913 Ovarian steroidogenesis
129012612 (ADCY4)
04915 Estrogen signaling pathway
129012612 (ADCY4)
04914 Progesterone-mediated oocyte maturation
129012612 (ADCY4)
04921 Oxytocin signaling pathway
129012612 (ADCY4)
04926 Relaxin signaling pathway
129012612 (ADCY4)
04935 Growth hormone synthesis, secretion and action
129012612 (ADCY4)
04918 Thyroid hormone synthesis
129012612 (ADCY4)
04928 Parathyroid hormone synthesis, secretion and action
129012612 (ADCY4)
04916 Melanogenesis
129012612 (ADCY4)
04925 Aldosterone synthesis and secretion
129012612 (ADCY4)
04927 Cortisol synthesis and secretion
129012612 (ADCY4)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
129012612 (ADCY4)
04270 Vascular smooth muscle contraction
129012612 (ADCY4)
09154 Digestive system
04970 Salivary secretion
129012612 (ADCY4)
04971 Gastric acid secretion
129012612 (ADCY4)
04972 Pancreatic secretion
129012612 (ADCY4)
04976 Bile secretion
129012612 (ADCY4)
09156 Nervous system
04724 Glutamatergic synapse
129012612 (ADCY4)
04727 GABAergic synapse
129012612 (ADCY4)
04725 Cholinergic synapse
129012612 (ADCY4)
04723 Retrograde endocannabinoid signaling
129012612 (ADCY4)
09157 Sensory system
04742 Taste transduction
129012612 (ADCY4)
04750 Inflammatory mediator regulation of TRP channels
129012612 (ADCY4)
09149 Aging
04211 Longevity regulating pathway
129012612 (ADCY4)
04213 Longevity regulating pathway - multiple species
129012612 (ADCY4)
09159 Environmental adaptation
04713 Circadian entrainment
129012612 (ADCY4)
04714 Thermogenesis
129012612 (ADCY4)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129012612 (ADCY4)
05207 Chemical carcinogenesis - receptor activation
129012612 (ADCY4)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
129012612 (ADCY4)
05163 Human cytomegalovirus infection
129012612 (ADCY4)
09165 Substance dependence
05032 Morphine addiction
129012612 (ADCY4)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
129012612 (ADCY4)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
129012612 (ADCY4)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
129012612 (ADCY4)
Enzymes [BR:
ppyg01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
129012612 (ADCY4)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Guanylate_cyc
Adcy_cons_dom
AC_N
CD52
Motif
Other DBs
NCBI-GeneID:
129012612
NCBI-ProteinID:
XP_054304465
LinkDB
All DBs
Position
15:complement(22494988..22510628)
Genome browser
AA seq
1077 aa
AA seq
DB search
MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLGIVLCALAALLAVAWASGRELTSDPS
FLTTVLCALGGFSLLLGLASREQRLQRWTRPLSGLVWVALLALGHAFLFTGGVVSAWDQV
SYFLFVIFTAYAMLPLGMRDAAVAGLASSLSHLLVLGLYLGPQPDSRPALLPQLAANAVL
FLCGNVAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK
AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE
LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG
VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG
AYAVEDAGMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGLKMRPSLLMTR
YLESWGAAKPFAHLSHGDSPVSTSTPLPEKTLASFSPQWSLDRSRTPRGLDDELDTGDAK
FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSAIPAFKYYEACTFLVFLSNFI
IQMLVTNRPPALAITYSITFLLFLLILFVCFSEDLMRCVLKGPKMLHWLPALSGLVATRP
GLRIALGTATILLVFAMAITSLFFFPTSSDCPFQAPNVSSMISNLSWELPGSLPLISVPY
SMHCCTLGFLSCSLFLHMSFELKLLLLLLWLAASCSLFLHSHAWLSECLIVRLYLGPLDS
RPGVLKEPKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRL
LLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLR
LLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQDAERSCSHLGTMV
EFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST
GVLGKIQVTEETAWALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRTGPPSATLG
NT seq
3234 nt
NT seq
+upstream
nt +downstream
nt
atggcccgcctcttcagcccccggccgccccccagcgaagacctcttctacgagacctac
tacagcctgagccagcagtacccgctgctgctgctgctgctggggatcgtgctctgtgcg
ctcgcggcgctgctcgccgtggcctgggccagcggcagggagctgacctcagacccgagc
ttcctgaccactgtgctgtgcgcgctgggcggcttctcgctgctgctgggcctcgcttcc
cgcgagcagcgactgcagcgctggacgcgtcccctgtccggcttggtatgggtcgcgctg
ctagcgctaggccacgccttcctgttcaccgggggcgtggtgagcgcctgggaccaggtg
tcctattttctcttcgtcatcttcacggcgtatgccatgctgcctttgggcatgcgggac
gccgccgtcgcgggcctcgcctcctcactctcgcatctgctggtcctcgggctgtatctt
gggccacagccggactcacggcctgcactgctgccgcagttggcagcaaacgcggtgctg
ttcctgtgcgggaacgtggcaggagcgtaccacaaggcgctgatggagcgcgccctgcgg
gccacgttccgggaggcactcagctccctgcactcacgccggcggctggacaccgagaag
aagcaccaggaacaccttctcttatccatccttcctgcctacctggcccgagagatgaag
gcagagatcatggcacggctgcaggcaggacaggggtcacggccagagagcaccaacaat
ttccacagcctctatgtcaagaggcaccagggagtcagcgtgctgtatgctgacatcgtg
ggcttcacacggctggccagcgagtgttcccctaaggagctggtgctcatgctcaatgag
ctctttggcaagttcgaccagatcgccaaggagcatgaatgcatgcggatcaagatcctg
ggggactgttactactgtgtctccgggctgccactctcactgccagaccatgccatcaac
tgcgtgcgcatggggctggacatgtgccgggccatcaggaaactgcgggcagccactggc
gtggacatcaacatgcgtgtgggcgtgcactcaggcagcgtactgtgtggagtcatcggg
ctgcagaagtggcagtacgacgtttggtcccatgatgtcacactggctaaccacatggaa
gcaggcggtgtaccagggcgagtgcacatcacaggggctaccctggccctgctggcaggg
gcttatgctgtggaggacgcaggcatggagcatcgggacccttaccttcgggagctaggg
gagcctacctatctggtcatcgatccacgggcagaggaggaggatgagaagggcactgca
ggaggcttgctgtcctcgcttgagggcctcaagatgcgtccatcactgctgatgacccgt
tacctggagtcctggggcgcagccaagccttttgcccacctgagccacggagacagccct
gtgtccacctccacccctctcccggagaagaccctggcttccttcagcccccagtggagc
ctggatcggagccgtaccccccggggactagatgatgaactggacaccggggatgccaag
ttcttccaggtcattgagcagctcaactcgcagaaacagtggaagcagtcgaaggacttc
aacccactgacactgtacttcagagagaaggagatggagaaagagtaccgactctctgca
atccccgccttcaaatactatgaagcttgcaccttcctggtttttctctccaacttcatc
atccagatgctagtgacaaacaggcccccagctctggcgatcacgtatagcatcaccttc
ctcctcttcctcctcatcctttttgtctgcttctcagaggacctgatgaggtgtgtcctg
aaaggccccaagatgctgcactggctgcctgcactgtctggcctggtggccacacgacca
ggactgagaatagccttgggcaccgccaccatcctccttgtctttgccatggccattacc
agcctgttcttcttcccaacatcatcagactgccctttccaagctcccaatgtgtcctcc
atgatttccaacctctcctgggagctccctgggtctctgcctctcatcagtgtcccatac
tccatgcactgctgcacactgggcttcctctcctgctccctgtttctgcacatgagcttc
gagctgaagctgctgctgctcctgctgtggctggcggcatcctgctccctcttcctgcac
tcccacgcctggctgtctgaatgtctcatcgtccgcctctatctgggccccttggactcc
aggcccggagtgctgaaggagcccaaactgatgggtgctatctccttcttcatcttcttc
ttcaccctccttgtcctggctcgccagaatgagtactactgccgcctggacttcctgtgg
aagaagaagctgaggcaggagcgggaggagacagagacgatggagaacctgactcggctg
ctcttggagaacgtgctccctgcacacgtggccccccagttcattggccagaaccggcgc
aacgaggatctctaccaccagtcctacgaatgcgtttgtgtcctcttcgcctcagtccca
gacttcaaggagttctactctgaatccaacatcaatcatgagggcctagagtgtctgagg
ctgctcaatgagataattgctgattttgatgagctgctctccaagcccaagttcagtggg
gtggagaagatcaagaccatcggcagcacctacatggcagccacaggcttaaatgccacc
tctggacaggatgcacaacaggatgctgaacggagctgcagccaccttggcactatggtg
gaatttgccgtggccctggggtctaagctggacgtcatcaacaagcattcattcaacaac
ttccgcctgcgtgtggggttgaaccatggaccagtagtagctggagttattggggcccag
aagccgcaatatgacatttggggcaacacagtgaacgtggccagccgcatggagagtaca
ggagtccttggcaaaatccaagtgactgaggagacagcatgggccctacagtccctgggc
tacacctgctacagccggggtgtcatcaaggtgaaaggcaaagggcagctctgcacctac
ttcctgaacacagacttgacacgaactggacctccttcagctaccctaggctga
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