KEGG   Pongo pygmaeus (Bornean orangutan): 129012690
Entry
129012690         CDS       T10128                                 
Symbol
EIF2S1
Name
(RefSeq) eukaryotic translation initiation factor 2 subunit 1
  KO
K03237  translation initiation factor 2 subunit 1
Organism
ppyg  Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg04137  Mitophagy - animal
ppyg04140  Autophagy - animal
ppyg04141  Protein processing in endoplasmic reticulum
ppyg04156  Integrated stress response (ISR) signaling pathway
ppyg04210  Apoptosis
ppyg04932  Non-alcoholic fatty liver disease
ppyg05010  Alzheimer disease
ppyg05012  Parkinson disease
ppyg05014  Amyotrophic lateral sclerosis
ppyg05020  Prion disease
ppyg05022  Pathways of neurodegeneration - multiple diseases
ppyg05160  Hepatitis C
ppyg05162  Measles
ppyg05164  Influenza A
ppyg05168  Herpes simplex virus 1 infection
ppyg05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ppyg00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    129012690 (EIF2S1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    129012690 (EIF2S1)
   04137 Mitophagy - animal
    129012690 (EIF2S1)
  09143 Cell growth and death
   04210 Apoptosis
    129012690 (EIF2S1)
   04156 Integrated stress response (ISR) signaling pathway
    129012690 (EIF2S1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    129012690 (EIF2S1)
   05164 Influenza A
    129012690 (EIF2S1)
   05162 Measles
    129012690 (EIF2S1)
   05168 Herpes simplex virus 1 infection
    129012690 (EIF2S1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    129012690 (EIF2S1)
   05012 Parkinson disease
    129012690 (EIF2S1)
   05014 Amyotrophic lateral sclerosis
    129012690 (EIF2S1)
   05020 Prion disease
    129012690 (EIF2S1)
   05022 Pathways of neurodegeneration - multiple diseases
    129012690 (EIF2S1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    129012690 (EIF2S1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    129012690 (EIF2S1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03012 Translation factors [BR:ppyg03012]
    129012690 (EIF2S1)
   04131 Membrane trafficking [BR:ppyg04131]
    129012690 (EIF2S1)
Translation factors [BR:ppyg03012]
 Eukaryotic type
  Initiation factors
   eIF-2
    129012690 (EIF2S1)
Membrane trafficking [BR:ppyg04131]
 Autophagy
  ER-phagy
   ER stress-related proteins
    129012690 (EIF2S1)
SSDB
Motif
Pfam: EIF_2_alpha S1
Other DBs
NCBI-GeneID: 129012690
NCBI-ProteinID: XP_054304607
LinkDB
Position
15:66228328..66262115
AA seq 315 aa
MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSIN
KLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLE
YTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNI
NRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTT
TLERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQMERLERENAEV
DGDDDAEEMEAKAED
NT seq 948 nt   +upstreamnt  +downstreamnt
atgccgggtctaagttgtagattttatcaacacaaatttcctgaggtggaagatgtagtg
atggtgaatgtcagatccattgctgaaatgggggcttatgtcagcttgctggaatacaac
aacattgaaggcatgattcttcttagtgaattatccagaaggcgtatccgttctatcaac
aaactcatccgaattggcaggaatgagtgcgtggttgtcattagggtggacaaagaaaaa
ggatatattgatttgtcaaaaagaagagtttctccagaggaagcaatcaaatgtgaagac
aaattcacaaaatccaaaactgtttatagcatacttcgtcatgttgctgaggtgttagaa
tacaccaaggatgagcagctggaaagcctattccagaggactgcctgggtctttgatgac
aagtacaagagacctggatatggtgcctatgatgcatttaagcatgcagtctcagaccca
tctattttggatagtttagatttgaatgaagatgaacgggaagtactcattaataatatt
aataggcgcttgaccccacaggctgtcaaaattcgagcagatatcgaagtggcttgttat
ggttatgaaggcattgatgctgtaaaagaagccctaagagcaggtttgaattgttctaca
gaaaacatgcccattaagattaatctaatagctcctcctcggtatgtaatgactacgaca
accctggagagaacagaaggcctttctgtcctcagtcaagctatggctgttatcaaagaa
aagattgaggaaaagaggggtgtgttcaatgttcaaatggagcccaaagtggtcacagat
acagatgagactgaacttgcgaggcagatggagaggcttgaaagagaaaatgccgaagtg
gatggagatgatgatgcagaagaaatggaagccaaagctgaagattaa

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