Pongo pygmaeus (Bornean orangutan): 129013336
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Entry
129013336 CDS
T10128
Symbol
HIF1A
Name
(RefSeq) hypoxia-inducible factor 1-alpha isoform X1
KO
K08268
hypoxia-inducible factor 1 alpha
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg04066
HIF-1 signaling pathway
ppyg04137
Mitophagy - animal
ppyg04140
Autophagy - animal
ppyg04148
Efferocytosis
ppyg04659
Th17 cell differentiation
ppyg04919
Thyroid hormone signaling pathway
ppyg05167
Kaposi sarcoma-associated herpesvirus infection
ppyg05200
Pathways in cancer
ppyg05205
Proteoglycans in cancer
ppyg05208
Chemical carcinogenesis - reactive oxygen species
ppyg05211
Renal cell carcinoma
ppyg05230
Central carbon metabolism in cancer
ppyg05231
Choline metabolism in cancer
ppyg05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
129013336 (HIF1A)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
129013336 (HIF1A)
04137 Mitophagy - animal
129013336 (HIF1A)
04148 Efferocytosis
129013336 (HIF1A)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
129013336 (HIF1A)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
129013336 (HIF1A)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129013336 (HIF1A)
05205 Proteoglycans in cancer
129013336 (HIF1A)
05208 Chemical carcinogenesis - reactive oxygen species
129013336 (HIF1A)
05230 Central carbon metabolism in cancer
129013336 (HIF1A)
05231 Choline metabolism in cancer
129013336 (HIF1A)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
129013336 (HIF1A)
09162 Cancer: specific types
05211 Renal cell carcinoma
129013336 (HIF1A)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
129013336 (HIF1A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
ppyg03000
]
129013336 (HIF1A)
Transcription factors [BR:
ppyg03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
129013336 (HIF1A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
bHLH_HIF1A
PAS_3
PAS_11
HIF-1a_CTAD
PAS
HIF-1
PAS_9
PAS_4
HLH
DDRGK
Motif
Other DBs
NCBI-GeneID:
129013336
NCBI-ProteinID:
XP_054305870
LinkDB
All DBs
Position
15:60446011..60497747
Genome browser
AA seq
827 aa
AA seq
DB search
MEGAGGANDKKNRISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASV
MRLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKY
MGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGPVKKGKEQNTQRSFFLRMKCTLTSRG
RTMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDS
KTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQ
VTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTEC
VLKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTE
TDDQQLEEVPLYNDVMLPSPNEKLQNINLAMSPLPTAETPKPLRSSADPALNQEVALKLE
PNPESLELSFTMPQIQDQPPSPSDGSTRQSSPEPNSPSEYCFYVDSDMVNEFKLELVEKL
FAEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSASPESASPQSTV
TVFQQTQIQEPTANATTTTATTDELKTVTKDRMEDIKILIASPSPTHIHKETTSATSSPY
RDTQSRTASPNRAGKGVIEQTEKSHPRSPNVLSVALSQRTTVPEEELNPKILALQNAQRK
RKMEHDGSLFQAVGIGTLLQQPEDHAATTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLA
CRLLGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
NT seq
2484 nt
NT seq
+upstream
nt +downstream
nt
atggagggcgccggcggcgcgaacgacaagaaaaataggataagttctgaacgtcgaaaa
gaaaagtctcgagatgcagccagatctcggcgaagtaaagaatctgaagttttttatgag
cttgctcatcagttgccacttccacataatgtgagttcgcatcttgataaggcctctgtg
atgaggcttaccatcagctatttgcgtgtgaggaaacttctggatgctggtgatttggat
attgaagatgaaatgaaagcacagatgaattgcttttatttgaaagccttggatggtttt
gttatggttctcacagatgatggtgacatgatttacatttctgataatgtgaacaaatac
atgggattaactcagtttgaactaactggacacagtgtgtttgattttactcatccatgt
gaccatgaggaaatgagagaaatgcttacacacagaaatggccctgtgaaaaagggtaaa
gaacagaacacacagcgaagcttttttctcagaatgaagtgtaccctaactagccgagga
agaactatgaacataaagtctgcaacatggaaggtattgcactgcacaggccatattcac
gtatatgataccaacagtaaccaacctcagtgtgggtataagaaaccacctatgacctgc
ttggtgctgatttgtgaacccattcctcacccatcaaatattgaaattcctttagatagc
aagactttcctcagtcgacacagcctggatatgaaattttcttattgtgatgaaagaatt
accgaattgatgggatatgagccagaagaacttttaggccgctcaatttatgaatattat
catgctttggactctgatcatctgaccaaaactcatcatgacatgtttactaaaggacaa
gttaccacaggacagtacaggatgcttgccaaaagaggtggatatgtctgggttgaaact
caagcaactgtcatatataacaccaagaattctcaaccacagtgcattgtatgtgtgaat
tatgttgtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgt
gtccttaaaccggttgaatcttcagatatgaaaatgactcagctattcaccaaagttgaa
tcagaagacacaagtagcctctttgacaaacttaagaaggaacctgatgctttaactttg
ctggccccagccgctggagacacaatcatatctttagattttggcagcaatgacacagaa
actgatgaccagcaacttgaggaagtaccattatataatgatgtaatgctcccctcaccc
aacgaaaaattacagaatataaatttggcaatgtctccattacccaccgctgaaacacca
aagccacttcgaagtagtgctgaccctgcactcaatcaagaagttgcattaaaattagaa
ccaaatccagagtcactggaactttcttttaccatgccccagattcaggatcagccacct
agtccttctgatggaagcactagacaaagttcacctgagcctaatagtcccagtgaatat
tgtttttatgtggatagtgatatggtcaatgaattcaagttggaattggtagaaaaactt
tttgctgaagacacagaagcaaagaacccattttctactcaggacacagatttagacttg
gagatgttagctccctatatcccaatggatgatgacttccagttacgttccttcgatcag
ttgtcaccattagaaagcagttccgcaagccctgaaagcgcaagtcctcaaagcacagtt
acagtattccagcagactcaaatacaagaacctactgctaatgccaccactaccactgcc
accactgatgaattaaaaacagtgacaaaagaccgtatggaagacattaaaatactgatt
gcatctccatctcctacccacatacataaagaaactactagtgccacatcatcaccatat
agagatactcaaagtcggacagcctcaccaaacagagcaggaaaaggagtcatagaacag
acagaaaaatctcatccaagaagccctaacgtgttatctgtcgctttgagtcaaagaact
acagttcctgaggaagaactaaatccaaagatactagctttgcagaatgctcagagaaag
cgaaaaatggaacatgatggttcactttttcaagcagtaggaattggaacattattacag
cagccagaggatcatgcagctactacatcactttcttggaaacgtgtaaaaggatgcaaa
tctagtgaacagaatggaatggagcaaaagacaattattttaataccttctgatttagca
tgtagactgctggggcaatcaatggatgaaagtggattaccacagctgaccagttatgat
tgtgaagttaatgctcctatacaaggcagcagaaacctactgcagggtgaagaattactc
agagctttggatcaagttaactga
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