Pongo pygmaeus (Bornean orangutan): 129013747
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Entry
129013747 CDS
T10128
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg00020
Citrate cycle (TCA cycle)
ppyg00480
Glutathione metabolism
ppyg01100
Metabolic pathways
ppyg01200
Carbon metabolism
ppyg01210
2-Oxocarboxylic acid metabolism
ppyg01230
Biosynthesis of amino acids
ppyg04146
Peroxisome
ppyg05230
Central carbon metabolism in cancer
Module
ppyg_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ppyg_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
129013747 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
129013747 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
129013747 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
129013747 (IDH2)
Enzymes [BR:
ppyg01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
129013747 (IDH2)
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Paralog
GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
129013747
NCBI-ProteinID:
XP_054306376
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All DBs
Position
16:complement(95732632..95751074)
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AA seq
452 aa
AA seq
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MAGYLRVVRSLCRASGSRPAWAPAALTAPTSQEQPRRHYADRRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTTDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGVGMYNTDESISGFAHSCFQYAI
QKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESGAMTKDLAGCIH
GLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atggccggctacctgcgggtcgtgcgctcgctctgcagagcctcaggctcgcggccggcc
tgggcgccggcggccctgacagcccccacctcgcaagagcagccgcggcgccactatgcc
gacagaaggatcaaggtggcgaagcccgtggtggagatggatggtgatgagatgacccgt
atcatctggcagttcatcaaggagaagctcatcctgccccacgtggacatccagctaaag
tattttgacctcgggctcccaaaccgtgaccagaccgatgaccaggtcaccactgattct
gcactggccacccagaagtacagtgtggctgtcaagtgtgccaccatcacccctgatgag
gcccgtgtggaagagttcaagctgaagaagatgtggaaaagtcccaatggaactatccgg
aacatcctgggggggactgtcttccgggagcccatcatctgcaaaaacatcccacgccta
gtccctggctggaccaagcccatcaccataggcaggcacgcccatggcgaccagtacaag
gccacagactttgtggcagaccgggccggcacgttcaaaatggtcttcaccccaaaagac
ggcagcggtgtgaaggagtgggaagtgtacaacttccccgcaggcggcgtgggcgtgggc
atgtacaacaccgacgagtccatctcgggttttgcgcacagctgcttccagtatgccatc
cagaagaaatggccgctgtacatgagcaccaagaacaccatactgaaagcctacgatggg
cgtttcaaggacatcttccaggagatctttgacaagcactataagaccgacttcgacaag
aataagatctggtatgagcaccggctcattgacgacatggtggctcaggtcctgaagtct
tcgggcggctttgtgtgggcctgcaagaactatgacggagatgtgcagtcagacatcctg
gcccagggctttggctcccttggcctgatgacgtccgtcctggtctgccctgatgggaag
acaattgaggctgaggccgctcatgggaccgtcacccgccactatcgggagcaccagaag
ggccggcccaccagcaccaaccccatcgccagcatctttgcctggacacgcggcctggag
caccgggggaagctggatggaaaccaagacctcatcaggtttgcccagacgctggagaaa
gtgtgcgtggaaacggtggagagtggagccatgaccaaggacctggcgggctgcattcac
ggcctcagcaatgtgaagctgaacgagcacttcctgaacaccacggacttcctcgacacc
atcaagagcaacctggacagagccctgggcaggcagtag
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