Pongo pygmaeus (Bornean orangutan): 129013948
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Entry
129013948 CDS
T10128
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg01521
EGFR tyrosine kinase inhibitor resistance
ppyg01522
Endocrine resistance
ppyg04010
MAPK signaling pathway
ppyg04014
Ras signaling pathway
ppyg04015
Rap1 signaling pathway
ppyg04066
HIF-1 signaling pathway
ppyg04068
FoxO signaling pathway
ppyg04081
Hormone signaling
ppyg04114
Oocyte meiosis
ppyg04140
Autophagy - animal
ppyg04144
Endocytosis
ppyg04150
mTOR signaling pathway
ppyg04151
PI3K-Akt signaling pathway
ppyg04152
AMPK signaling pathway
ppyg04211
Longevity regulating pathway
ppyg04213
Longevity regulating pathway - multiple species
ppyg04510
Focal adhesion
ppyg04520
Adherens junction
ppyg04550
Signaling pathways regulating pluripotency of stem cells
ppyg04730
Long-term depression
ppyg04913
Ovarian steroidogenesis
ppyg04914
Progesterone-mediated oocyte maturation
ppyg05200
Pathways in cancer
ppyg05202
Transcriptional misregulation in cancer
ppyg05205
Proteoglycans in cancer
ppyg05214
Glioma
ppyg05215
Prostate cancer
ppyg05218
Melanoma
ppyg05224
Breast cancer
ppyg05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
129013948 (IGF1R)
04014 Ras signaling pathway
129013948 (IGF1R)
04015 Rap1 signaling pathway
129013948 (IGF1R)
04066 HIF-1 signaling pathway
129013948 (IGF1R)
04068 FoxO signaling pathway
129013948 (IGF1R)
04151 PI3K-Akt signaling pathway
129013948 (IGF1R)
04152 AMPK signaling pathway
129013948 (IGF1R)
04150 mTOR signaling pathway
129013948 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
129013948 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
129013948 (IGF1R)
04140 Autophagy - animal
129013948 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
129013948 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
129013948 (IGF1R)
04520 Adherens junction
129013948 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
129013948 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
129013948 (IGF1R)
04914 Progesterone-mediated oocyte maturation
129013948 (IGF1R)
09156 Nervous system
04730 Long-term depression
129013948 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
129013948 (IGF1R)
04213 Longevity regulating pathway - multiple species
129013948 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129013948 (IGF1R)
05202 Transcriptional misregulation in cancer
129013948 (IGF1R)
05205 Proteoglycans in cancer
129013948 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
129013948 (IGF1R)
05214 Glioma
129013948 (IGF1R)
05218 Melanoma
129013948 (IGF1R)
05215 Prostate cancer
129013948 (IGF1R)
05224 Breast cancer
129013948 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
129013948 (IGF1R)
01522 Endocrine resistance
129013948 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppyg01001
]
129013948 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ppyg04090
]
129013948 (IGF1R)
Enzymes [BR:
ppyg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
129013948 (IGF1R)
Protein kinases [BR:
ppyg01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
129013948 (IGF1R)
CD molecules [BR:
ppyg04090
]
Proteins
129013948 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
129013948
NCBI-ProteinID:
XP_054306694
LinkDB
All DBs
Position
16:104401596..104716079
Genome browser
AA seq
1367 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRH
NYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
EPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPAFL
EIISSIKDEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRH
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttctctcc
gcggcgctctcgctctggccgacgagtggagaaatctgtgggccaggcatcgacatccgc
aacgactatcagcagctgaagcgcctggagaactgcacggtgatcgagggctacctccac
atcctgctcatctccaaggccgaggactaccgcagctaccgcttccccaagctcacggtc
attaccgagtacttgctgctgttccgagtggctggcctcgagagcctcggagacctcttc
cccaacctcacggtcatccgcggctggaaactcttctacaactacgccctggtcatcttc
gagatgaccaatctcaaggatattgggctttacaacctgaggaacattactcggggggcc
atcaggattgagaaaaatgctgacctctgttacctctccactgtggactggtccctgatc
ctggatgcagtgtccaataactacattgtggggaataagcccccaaaggaatgtggggac
ctgtgtccagggaccatggaggagaagccgatgtgtgagaagaccaccatcaacaatgag
tacaactaccgctgctggaccacaaaccgctgccagaaaatgtgcccgagcgcatgtggg
aagcgagcgtgcaccgagaacaacgagtgctgtcaccccgagtgcctgggcagctgcagc
gcgcctgacaacgacacggcctgcgtagcttgccgccactactactacgccggtgtctgc
gtgcctgcctgcccgcccaacacctacaggtttgagggctggcgctgtgtggaccgtgac
ttctgcgccaacatcctcagcgccgagagcagcgactccgaggggtttgtgatccacgac
ggcgagtgcatgcaggagtgcccctcgggcttcatccgcaacggcagccagagcatgtac
tgcatcccatgtgaaggtccttgccccaaggtctgtgaggaagaaaagaaaacaaagacc
attgattctgttacttctgctcagatgctccaaggatgcaccatcttcaagggcaatttg
ctcattaacatccgacgggggaataacattgcttcagaactggagaacttcatggggctc
atcgaggtggtgacgggctacgtgaagatccgccattctcatgccttggtctccttgtcc
ttcctaaaaaaccttcgcctcatcttaggagaggagcagctagaagggaattactccttc
tacgtcctcgacaaccagaacttgcagcaactatgggactgggaccaccgcaacctgacc
atcaaagcagggaaaatgtactttgctttcaatcccaaattatgtgtttctgaaatttac
cgcatggaggaagtgacggggactaaaggacgccaaagcaaaggggacataaacaccagg
aacaacggggagagagcctcctgtgaaagtgatgtcctgcatttcacctccaccaccacg
tcgaagaatcgcatcatcataacctggcaccggtaccggccccctgactacagggatctc
atcagcttcaccgtttactacaaggaagcaccctttaagaatgtcacggagtatgatggg
caggacgcctgcggctccaacagctggaacatggtggacgtggacctcccacccaacaag
gacgtggagcccggcatcttactgcatgggctgaagccctggactcagtacgccgtttac
gtcaaggctgtgaccctcaccatggtggagaacgaccatatccgtggagccaagagtgag
atcttgtacattcgcaccaatgcttcagttccttccattcccttggacgttctttcagca
tcgaactcctcttctcagttaatcgtgaagtggaaccctccctctctgcccaacggcaac
ctgagttactacattgtgcgctggcagcggcagcctcaggacggctacctttaccggcac
aattactgctccaaagacaaaatccccatcaggaagtatgccgacggcaccatcgacatt
gaggaggtcacagagaaccccaagactgaggtgtgtggtggtgagaaaggaccttgctgc
gcctgccccaaaactgaagccgagaagcaggccgagaaggaggaggctgagtaccgcaaa
gtctttgagaatttcctgcacaactccatcttcgtgcccagacctgaaaggaagcggaga
gatgtcatgcaagtggccaacaccaccatgtccagccgaagcaggaacaccacggccgca
gacacgtacaacatcaccgacccagaagagctggagacagagtaccctttctttgagagc
agagtggataacaaggagagaactgtcatttctaaccttcggcctttcacattgtaccgc
atcgatatccacagctgcaaccatgaggctgagaagctgggctgcagcgcctccaacttc
gtctttgcaaggactatgcccgcagaaggagcagatgacattcctgggccagtgacctgg
gagccaaggcctgaaaactccatctttttaaagtggccagaacctgagaatcccaatgga
ttgattctaatgtatgaaataaaatacggatcacaagttgaggatcagcgagaatgtgtg
tccagacaggaatacaggaagtatggaggggccaagctaaaccggctaaacccggggaac
tacacagcccggattcaggccacatctctctctgggaatgggtcgtggacagatcctgtg
ttcttctatgtccaggccaaaacaggatatgaaaacttcatccatctgatcatcgctctg
cccgtcgctgtcctgttgattgtgggagggttggtgattatgctgtacgtcttccataga
aagagaaataacagcaggctggggaatggagtgctgtatgcctctgtgaacccggagtac
ttcagcgctgcggatgtgtacgttcctgatgagtgggaggtggctcgggagaagatcacc
atgagccgggaacttgggcaggggtcgtttgggatggtctatgaaggagttgccaagggt
gtggtgaaagatgaacctgaaaccagagtggccattaaaacagtgaacgaggccgcaagc
atgcgtgaaaggatcgagtttctcaacgaagcttctgtgatgaaggagttcaattgtcac
catgtggtgcgattgctgggtgtggtgtcccaaggccagccaacactggtcatcatggaa
ctgatgacacggggcgatctcaaaagttatctccggtctctgaggccagaaatggagaat
aatccagtcctagcacctccaagcctaagcaagatgattcagatggccggagagattgca
gacggcatggcatacctcaacgccaacaagttcgtccacagagaccttgctgcccggaat
tgcatggtagccgaagatttcacagtcaaaatcggagattttggtatgacgcgagatatc
tatgagacagactattaccggaaaggagggaaagggctgctgcccgtgcgctggatgtct
cccgagtccctcaaggatggagtcttcaccacttactcggacgtctggtccttcggggtc
gtcctctgggagattgccacactggccgagcagccctaccagggcttgtccaacgagcaa
gtccttcgcttcgtcatggagggcggccttctggacaagccagacaactgtcctgacatg
ctgtttgaactgatgcgcatgtgctggcagtataaccccaagatgaggcctgccttcctg
gagatcatcagcagcatcaaagacgagatggagcctggcttccgggaggtctccttctac
tacagcgaggagaacaagctgcccgagccggaggaactggacctcgagccagagaacatg
gagagcgtccccctggacccctcggcctcctcgtcctccctgccactgcccgacagacac
tcaggacacaaggccgagaacggccccggccctggagtgctggtcctccgcgccagcttc
gacgagagacagccttacgcacacatgaacgggggccgcaagaacgagcgggccttgcca
ctgccccagtcttcgacctgctga
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