Pongo pygmaeus (Bornean orangutan): 129015265 Help Entry 129015265         CDS       T10128                                  Symbol ADCY7 Name (RefSeq) adenylate cyclase type 7   KO K08047   adenylate cyclase 7 [EC:4.6.1.1] Organism ppyg  Pongo pygmaeus (Bornean orangutan) Pathway ppyg00230   Purine metabolism ppyg01100   Metabolic pathways ppyg01522   Endocrine resistance ppyg04015   Rap1 signaling pathway ppyg04020   Calcium signaling pathway ppyg04022   cGMP-PKG signaling pathway ppyg04024   cAMP signaling pathway ppyg04062   Chemokine signaling pathway ppyg04072   Phospholipase D signaling pathway ppyg04081   Hormone signaling ppyg04082   Neuroactive ligand signaling ppyg04114   Oocyte meiosis ppyg04211   Longevity regulating pathway ppyg04213   Longevity regulating pathway - multiple species ppyg04261   Adrenergic signaling in cardiomyocytes ppyg04270   Vascular smooth muscle contraction ppyg04371   Apelin signaling pathway ppyg04540   Gap junction ppyg04611   Platelet activation ppyg04713   Circadian entrainment ppyg04714   Thermogenesis ppyg04723   Retrograde endocannabinoid signaling ppyg04724   Glutamatergic synapse ppyg04725   Cholinergic synapse ppyg04727   GABAergic synapse ppyg04750   Inflammatory mediator regulation of TRP channels ppyg04911   Insulin secretion ppyg04912   GnRH signaling pathway ppyg04913   Ovarian steroidogenesis ppyg04914   Progesterone-mediated oocyte maturation ppyg04915   Estrogen signaling pathway ppyg04916   Melanogenesis ppyg04918   Thyroid hormone synthesis ppyg04921   Oxytocin signaling pathway ppyg04923   Regulation of lipolysis in adipocytes ppyg04925   Aldosterone synthesis and secretion ppyg04926   Relaxin signaling pathway ppyg04927   Cortisol synthesis and secretion ppyg04928   Parathyroid hormone synthesis, secretion and action ppyg04934   Cushing syndrome ppyg04935   Growth hormone synthesis, secretion and action ppyg04970   Salivary secretion ppyg04971   Gastric acid secretion ppyg04972   Pancreatic secretion ppyg04976   Bile secretion ppyg05032   Morphine addiction ppyg05163   Human cytomegalovirus infection ppyg05166   Human T-cell leukemia virus 1 infection ppyg05200   Pathways in cancer ppyg05207   Chemical carcinogenesis - receptor activation ppyg05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ppyg00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     129015265 (ADCY7)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     129015265 (ADCY7)    04371 Apelin signaling pathway     129015265 (ADCY7)    04020 Calcium signaling pathway     129015265 (ADCY7)    04072 Phospholipase D signaling pathway     129015265 (ADCY7)    04024 cAMP signaling pathway     129015265 (ADCY7)    04022 cGMP-PKG signaling pathway     129015265 (ADCY7)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     129015265 (ADCY7)    04081 Hormone signaling     129015265 (ADCY7)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     129015265 (ADCY7)   09144 Cellular community - eukaryotes    04540 Gap junction     129015265 (ADCY7)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     129015265 (ADCY7)    04062 Chemokine signaling pathway     129015265 (ADCY7)   09152 Endocrine system    04911 Insulin secretion     129015265 (ADCY7)    04923 Regulation of lipolysis in adipocytes     129015265 (ADCY7)    04912 GnRH signaling pathway     129015265 (ADCY7)    04913 Ovarian steroidogenesis     129015265 (ADCY7)    04915 Estrogen signaling pathway     129015265 (ADCY7)    04914 Progesterone-mediated oocyte maturation     129015265 (ADCY7)    04921 Oxytocin signaling pathway     129015265 (ADCY7)    04926 Relaxin signaling pathway     129015265 (ADCY7)    04935 Growth hormone synthesis, secretion and action     129015265 (ADCY7)    04918 Thyroid hormone synthesis     129015265 (ADCY7)    04928 Parathyroid hormone synthesis, secretion and action     129015265 (ADCY7)    04916 Melanogenesis     129015265 (ADCY7)    04925 Aldosterone synthesis and secretion     129015265 (ADCY7)    04927 Cortisol synthesis and secretion     129015265 (ADCY7)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     129015265 (ADCY7)    04270 Vascular smooth muscle contraction     129015265 (ADCY7)   09154 Digestive system    04970 Salivary secretion     129015265 (ADCY7)    04971 Gastric acid secretion     129015265 (ADCY7)    04972 Pancreatic secretion     129015265 (ADCY7)    04976 Bile secretion     129015265 (ADCY7)   09156 Nervous system    04724 Glutamatergic synapse     129015265 (ADCY7)    04727 GABAergic synapse     129015265 (ADCY7)    04725 Cholinergic synapse     129015265 (ADCY7)    04723 Retrograde endocannabinoid signaling     129015265 (ADCY7)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     129015265 (ADCY7)   09149 Aging    04211 Longevity regulating pathway     129015265 (ADCY7)    04213 Longevity regulating pathway - multiple species     129015265 (ADCY7)   09159 Environmental adaptation    04713 Circadian entrainment     129015265 (ADCY7)    04714 Thermogenesis     129015265 (ADCY7)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     129015265 (ADCY7)    05207 Chemical carcinogenesis - receptor activation     129015265 (ADCY7)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     129015265 (ADCY7)    05163 Human cytomegalovirus infection     129015265 (ADCY7)   09165 Substance dependence    05032 Morphine addiction     129015265 (ADCY7)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     129015265 (ADCY7)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     129015265 (ADCY7)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     129015265 (ADCY7) Enzymes [BR:ppyg01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      129015265 (ADCY7) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N Motif Other DBs NCBI-GeneID:  129015265 NCBI-ProteinID:  XP_063511098 LinkDB All DBs Position 18:47321591..47395132 Genome browser AA seq 1080 aa AA seqDB search MPTKGRYFLNEGEEGPDQDALYEKYQLTSHHGPLLLTLLLVAATACVALIIIVFSQGDPS RHQAILGMAFLALAVFAALSVLMYVECLLRRWLRALALLTWACLVVLGYVLVFDAWTKAA CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGALMGGFTTPSVRVGLQL LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ VREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA SVRMTRYLESWGAARPFAHLNHRESVSSGETPVPNGRRPKSVPQRHRRTPDRSMSPKGRS EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA SLIFICILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFPVPELPVGNETGLPAASSKTRALCEPLP YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQGDCCGQGLGNLTEP NSTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKNEHEEFET MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVTSGHENQELERQHAH IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS RMESTGELGKIQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKFQGLGLN NT seq 3243 nt NT seq  +upstreamnt  +downstreamnt atgccaacaaaggggcgctacttcctcaacgagggcgaggagggccctgaccaagatgcg ctctacgagaagtaccagctcaccagccatcatgggccgctgctgctcacgctcctgctg gtggccgccactgcctgtgtggccctcatcatcatcgtcttcagccagggggacccctcc agacaccaggccattctgggcatggcgttcctggcgctggcggtgtttgcagccctctct gtgctgatgtacgtcgagtgtctcctgcggcgctggctcagggccttggcgctgctcacc tgggcctgcttggtggtgctgggctacgtgctggtgtttgacgcatggacaaaggcggcc tgtgcgtgggagcaggtgcccttcttcctgttcatcgtcttcgtggtgtacacactgctg cccttcagcatgcggggcgctgtcgccgttggggccgtctctactgcctcccacctcctg gtgctcggtgctttgatgggaggcttcacaacacccagtgtccgggtggggctgcagctg ctggccaacgcagtcatcttcctgtgcgggaacctgacaggcgccttccacaagcaccaa atgcaggatgcgtcccgggacctcttcacctacactgtgaagtgcatccagatccgccgg aagctgcgcatcgagaagcgccagcaggagaacctgctgctgtcggtgcttccggcccac atctccatgggcatgaagctggccatcattgaacggctcaaggagcatggcgaccgtcgc tgcatgcctgacaacaacttccacagcctctacgtcaaaaggcaccagaatgtcagcatc ctctatgcggacattgtgggcttcacgcagctggccagcgactgttcccccaaggagttg gtggtggtgctgaatgagctctttggcaagttcgaccagatcgccaaggccaacgagtgc atgcgaatcaagatcctcggtgactgctactactgtgtatcgggcctgcccgtgtcgctg cccacccacgcccggaactgcgtgaagatggggctggacatgtgccaggccatcaagcag gtgcgggaggccacgggcgtggacatcagcatgcgtgtgggcatacactcggggaatgtg ctgtgcggggtcatcgggctgcgcaaatggcagtatgacgtgtggtcccacgatgtgtcc ctggccaaccggatggaggcagccggagtacccggccgtgtgcacatcacggaggcgacg ctgaagcacctggacaaggcgtacgaggtggaagacgggcacgggcagcagcgggacccc tacctcaaggagatgaacatccgaacctacctggtcatcgacccccggagccagcagcca cccccgcccagccaacacctccccaggcccaagggagacgcggccctgaagatgcgggcg tcagtgcgcatgacccggtacctcgagtcctggggggcggcacggccctttgcgcatctc aaccaccgtgagagcgtgagcagtggtgagacccccgtccccaacgggcggaggcctaag agcgttccccagcgccaccgccggaccccagacagaagcatgtcccccaaggggcggtcg gaggatgactcgtacgatgatgagatgctgtcagccatcgaggggctcagctccacgagg ccctgctgctccaagtccgacgacttctacactttcgggtccatcttcctggagaagggc tttgagcgcgagtaccgcctggcacccatcccccgggcccgccacgactttgcctgcgcc agcctgatcttcatctgcatcctgctcgtccatgtcctgctcatgcccaggacggcggca ctgggtgtgtccttcgggctggtggcctgtgtactggggctggtgctgggcctgtgcttt gccaccaagttctcgaggtgctgcccagcccgggggacgctctgcactatctctgagagg gtggagacgcagcccctgctgaggctgaccctggccgtcctgaccatcggcagcctgctc actgtggccatcatcaacctgcccctgatgcctttcccagtcccagagctgcctgttggc aatgagacaggcctaccggccgcaagcagcaagacaagagccctgtgcgagcccctcccg tactacacctgcagctgtgtcctgggcttcatcgcctgctccgtcttcctgaggatgagc ctggagccaaaggttgtgctgctgacagtggccctggtggcctacctggtgctcttcaac ctctccccatgctggcagggggactgctgcggccaaggcctgggcaacctcactgagccc aacagcaccaccagcggcacccctagctgttcctggaaggacctgaagaccatgaccaat ttctacctggtcctgttctacatcaccctgctcactctctccagacagatagactattac tgccgcttggactgcctatggaagaagaagttcaagaacgagcacgaggagtttgagacc atggagaatgtgaaccgccttcttctggagaacgtcctgccagcccacgtggccgcccac tttattggtgacaagttaaacgaggactggtaccatcagtcctatgactgcgtctgtgtc atgtttgcctccgtaccggactttaaagtgttctacacggagtgtgatgtcaacaaagaa gggctggagtgcttgcgcctgctcaatgagatcattgccgacttcgacgagctcctactg aagcccaagttcagcggtgtggagaagatcaagaccatcggcagcacgtacatggcagct gcagggctcagtgtcacctcagggcacgagaaccaggagctggagcggcagcatgcccac attggtgtcatggtggagttcagcatcgccctgatgagtaagctggatggcatcaacagg cactccttcaactccttccgcctccgagtcggcataaaccatgggcctgtgattgctgga gtgattggggcccgaaaacctcagtatgacatctggggaaacacagtcaacgtggccagc cgaatggagagcactggagaacttgggaaaatccaggttaccgaggagacctgcaccatc ctccagggcctcgggtactcttgtgaatgccgtggcctgatcaatgtcaaaggcaaaggc gagctgaggacttactttgtctgtacggacactgccaagtttcaggggctggggctgaac tga

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