Pongo pygmaeus (Bornean orangutan): 129016936
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Entry
129016936 CDS
T10128
Symbol
PFAS
Name
(RefSeq) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg00230
Purine metabolism
ppyg01100
Metabolic pathways
Module
ppyg_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
129016936 (PFAS)
Enzymes [BR:
ppyg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
129016936 (PFAS)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-GeneID:
129016936
NCBI-ProteinID:
XP_054312742
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All DBs
Position
19:8113630..8135714
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AA seq
1338 aa
AA seq
DB search
MSPVLHFYVRPSGHEGAATGHTRRKLQGKLPELQGVETELCYNVNWTAEALPSAEETKKL
MWLFGCPLLLDDVARESWLLPGSNDLLLEVGPRLNFSTPTSTNIVSVCRAAGLGPVDRVE
TTRRYRLSFAHPPSAEVEAIALATLHDRMTEQHFPHPIQSFSPESIPEPLNGPINILGEG
RLALEKANQELGLALDSWDLDFYTKRFQELQRNPSTVEAFDLAQSNSEHSRHWFFKGQLH
VDGQKLVHSLFESIMSTQESSNPNNILKFCDNSSAIQGKEVRFLRPEDPTRPSRFQQQQG
LRHVVFTAETHNFPTGVCPFSGATTGTGGRIRDVQCTGRGAHVVAGTAGYCFGNLHIPGY
NLPWEDPSFQYSGNFARPLEVAIEASNGASDYGNKFGEPVLAGFARSLGLQLPDGQRREW
IKPIMFSGGIGSMEADHISKEAPEPGMEVVKVGGPVYRIGVGGGAASSVQVQGDNTSDLD
FGAVQRGDPEMEQKMNRVIRACVEAPEGNPICSLHDQGAGGNGNVLKELSDPAGAIIYTS
RFQLGDPTLNALEIWGAEYQESNALLLRSHDRDFLTHVSARERCPACFVGTITGDRRIVL
VDDRECPVGRNGQGDAPPTPPPTPVDLELEWVLGKMPRKEFFLQRKPPVLQPLALPPGLS
VRQALERVLRLPAVASKRYLTNKVDRSVGGLVAQQQCVGPLQTPLADVAVVALSHEELIG
AATALGEQPVKSLLDPKVAARLAVAEALTNLVFAVVTDLRDVKCSGNWMWAAKLPGEGAA
LADACEAMVAVMAALGVAVDGGKDSLSMAARVGTETVRAPGSLVISAYAVCPDITATVTP
DLKHPEGRGHLLYVPLSPGQHRLGGTALAQCFSQLGEHPPDLDLPENLVWAFSITQGLLK
DRLLCSGHDVSDGGLVTCLLEMAFAGNCGLQVDVPVPGVDVLSVLFAEEPGLVLEVQEPD
LAQVLKRYGDAGLHCLELGHTGGAGPHAMVRVSVNGAVVLEEPVGELRALWEETSFQLDR
LQAEPRCVAEEERGLRERMGPSYCLPPTFPKASVPREPGGPSPRVAILREEGSNGDREMA
DAFHLAGFEVWDVTMQDLCSGAIGLDTFRGVAFVGGFSYADVLGSAKGWAAAVTFHPRAG
AELRRFRKRPDTFSLGVCNGCQLLALLGWVGGDPNEDAAEMGPDSQPARPGLLLRHNLSG
RYESRWASVRVGPGPALMLRGMEGAVLPVWSAHGEGYVAFSSPELQAQIEARGLAPLHWA
DDDGNPTEQYPLNPNGSPGGVAGICSHDGRHLAVMPHPERAVRPWQWAWRPPPFDTLTTS
PWLQLFINARNWTLEGSC
NT seq
4017 nt
NT seq
+upstream
nt +downstream
nt
atgtccccagtccttcacttctatgttcgtccctctggccatgagggggcagccactgga
cacactcgaaggaaactgcaagggaaactgccagagctgcagggcgtcgagactgaactg
tgctacaatgtgaactggacagctgaggccctccccagtgctgaggagacaaagaagctg
atgtggctgtttggttgccccttattgctggatgatgttgctcgggagtcctggctcctt
cctggctccaatgacctgctgctggaggtcgggcccaggctgaacttctccaccccaaca
tccaccaacatcgtgtcagtgtgccgcgctgctgggctggggcctgtggatcgtgtggag
accacccggcgctaccggctctcgtttgcccaccccccgtcagctgaggtggaagccatt
gctctggctaccctgcacgaccggatgacagagcagcacttcccccatcccatccagagt
ttctcccctgagagcatccctgaacccctcaatggccctatcaatatactgggcgagggc
cggcttgcgctggagaaggccaaccaggagcttggtctggctttagactcttgggaccta
gacttctacaccaagcgcttccaggagctacagcggaacccgagcactgtggaggccttt
gacttggcgcagtccaatagcgagcacagccgacactggttcttcaagggccagctccac
gtggatgggcagaagctggtgcactcactgtttgagtccatcatgagcacccaggaatcc
tcgaaccccaacaacatcctcaaattctgtgataacagcagtgcaatccagggaaaggaa
gtccgattcctacggcctgaggaccctacacggccaagccgcttccagcaacagcaaggg
ctgagacacgttgtcttcacagcagagactcacaactttcccacaggagtatgccccttt
agtggtgcaaccactggcacagggggccggattcgagatgtccagtgcacaggccgcggg
gcccatgtggtggctggcactgccggctattgctttggaaatctgcatattccaggttac
aatctgccctgggaggatccaagcttccagtattctgggaactttgcccggcccctggag
gttgccattgaagccagtaatggagcttctgactatggcaacaagtttggggaaccagtg
ctggctggcttcgcccgctccttgggcctccagctcccagacggccagcggcgtgagtgg
atcaagcccatcatgtttagtgggggcattgggtccatggaagctgaccacataagcaag
gaggccccagagccaggcatggaagttgtaaaggttggaggtcccgtctacaggattgga
gttggaggtggagctgcttcatctgtgcaggtgcagggagataacaccagtgacctggac
ttcggggctgtgcagcgaggagacccggagatggaacagaagatgaaccgtgtgatcagg
gcttgtgtggaggcccccgagggaaaccccatctgcagccttcatgatcagggcgctggt
ggcaatggcaatgtcctaaaagagctgagtgacccagctggagccatcatttacaccagc
cgcttccagcttggggacccaaccctgaatgccctggaaatctggggggctgagtaccag
gaatcaaatgcacttctgctgaggtcccacgaccgggacttcctgactcatgtcagtgcc
cgtgaacgttgcccggcttgcttcgtgggcaccatcactggagaccggagaatagtgctg
gtggacgatcgagagtgtcctgtcggaagaaatggccagggggatgcccccccgacaccc
ccgccaacccctgtggacctggagctcgaatgggtgctgggcaagatgcctcggaaggag
ttcttcctgcagaggaagccccctgtgctgcagcctctggccttgcccccagggctgagc
gtgcgccaggccctggagagggttctgaggctgcctgccgtggccagcaagcgctacctc
accaataaggtggaccgctccgtgggcggcctggtggcccagcagcagtgcgtggggccc
ctgcagactcctctggcagatgtagcggttgtggcactgagccatgaggagctcataggg
gctgccacagccttgggagaacagccagtcaagagcctgctggacccaaaggtcgccgcc
cggctggccgtggccgaagccctcaccaatctggtgtttgctgtggtcactgacctccgg
gatgtgaagtgtagcgggaactggatgtgggcagccaagctcccaggggagggcgcagct
ttggcggatgcctgtgaggctatggtggcagtgatggcagccctgggtgtggcagtggac
ggtggcaaggactccctcagcatggctgcgcgggttggcaccgagaccgtgcgggctcct
gggtcactggtcatctcagcctatgccgtctgcccagacatcacagccaccgtgacccca
gacctcaagcatcctgaagggagaggccatctgctctatgtgcctctgagccctgggcag
caccggctggggggcacagctctggcccagtgcttctcccagctcggggagcaccctcca
gacctggaccttcctgagaacttggtgtgggccttcagcatcacccaggggctgctgaaa
gaccgcctcctctgctcaggccacgatgtcagtgacggaggcctcgtcacatgcctgctg
gagatggcctttgctggaaattgtgggctacaggtggatgtgcctgtccccggggttgat
gtcctgtctgtgctgttcgctgaggagccaggcctcgtgctggaggtgcaggagccagac
ctggcccaggtgctgaagcgttacggggatgctggcctccactgcctggagctgggccac
acaggcggggccgggccccacgccatggtccgggtgtcagtgaatggggctgtggttctg
gaggagcctgttggggagctgcgagccctctgggaggagacgagtttccagctggaccgg
ctacaggcagagcctcgctgtgtggcagaggaggaacggggcctgagggagcggatgggg
cccagctattgcctgccccccacttttcccaaagcctccgtgccccgtgagcctggtggt
cccagcccccgagtcgccatcttgcgagaggagggcagtaatggagaccgggagatggcc
gatgccttccacttggctgggtttgaggtatgggacgtgaccatgcaggacctctgctct
ggggcaattgggctggacactttccgtggcgtggccttcgtgggcggcttcagctatgct
gatgtcctgggctctgccaaagggtgggcagctgctgtgacctttcatcccagggctggg
gctgagctgaggcgcttccggaagcggccagacaccttcagcctgggcgtgtgtaatggc
tgtcaactgctggctctgctgggctgggtgggaggcgaccccaatgaggatgctgcagag
atgggccctgactcccagccagcccggccaggccttctgctacgtcacaacctgtctggg
cgctacgagtctcgctgggccagcgtgcgtgtggggcctgggccagccctgatgctgcga
ggaatggagggcgccgtgctgcccgtgtggagtgcacacggggaaggttacgtggcattt
tcttctccggaactccaagctcagattgaggccaggggcttggctcctctgcactgggcc
gatgatgatgggaaccccacagagcagtaccctctgaatcccaatgggtccccagggggc
gtggctggcatctgctcccatgatggccgccacctggctgtcatgcctcaccctgagcga
gccgtgaggccttggcagtgggcatggcgaccccctccatttgatactctgaccacctcc
ccctggctccagctctttatcaatgcccgaaactggaccctggaagggagctgctga
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