Pongo pygmaeus (Bornean orangutan): 129017961
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Entry
129017961 CDS
T10128
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg04140
Autophagy - animal
ppyg04141
Protein processing in endoplasmic reticulum
ppyg04210
Apoptosis
ppyg04932
Non-alcoholic fatty liver disease
ppyg05010
Alzheimer disease
ppyg05012
Parkinson disease
ppyg05014
Amyotrophic lateral sclerosis
ppyg05016
Huntington disease
ppyg05017
Spinocerebellar ataxia
ppyg05022
Pathways of neurodegeneration - multiple diseases
ppyg05417
Lipid and atherosclerosis
Brite
Enzymes [BR:
ppyg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
129017961 (ERN1)
Protein kinases [BR:
ppyg01001
]
Serine/threonine kinases: Other
IRE family
129017961 (ERN1)
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GFIT
Other DBs
NCBI-GeneID:
129017961
NCBI-ProteinID:
XP_054314988
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Position
19:complement(82306050..82396943)
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AA seq
978 aa
AA seq
DB search
MPARRLLLLLLLTLLLPGLGIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKE
DPVLQVPTHVEEPAFLPDPNDGSLYTLGSKNNEGLTKLPFTIPELVQASPCRSSDGILYM
GKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNAT
YFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLR
KVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPS
MVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDVKFDPGLKSKNKLNYLRNY
WLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTV
SRDVEEKPAHAPARPEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQ
FQKELEKIQLLQQQQQLPFHPPGDTAQDGELLDTSGPYSESSGTSSPSTSPRASNHSLCS
GSFASKAGSSPSLEQDDGDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVK
RILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFA
HLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKLA
VGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSL
QRQANILLGASSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQL
QFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRD
LLRAMRNKKHHYRELPAEVRETLGSLPDDFVCYFTSRFPHLLAHTYQAMELCSHERLFQP
YYFHEPPEPQPPVTPDAL
NT seq
2937 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggcggctgctgctgctgctgctgctgacgctgctgctgcccggcctcggg
atttttggaagtaccagcacagtgacgcttcctgaaaccttgttgtttgtgtcaacgctg
gatggaagtttgcatgctgtcagcaaaaggacaggctcaatcaaatggactttaaaagaa
gatccagtcctgcaggtcccaacacatgtggaagagcctgcctttctcccagatcctaat
gatggcagcctgtatacacttggaagcaagaataatgaaggcctgacgaaacttcctttt
accatcccagaattggtgcaggcatccccgtgccgaagttcagatggaatcctctacatg
ggtaaaaagcaggacatctggtatgttattgacctcctgaccggggagaagcagcagact
ttgtcatcggcctttgcagatagtctctgcccatcaacctctcttctgtatcttgggcga
acagaatacaccatcaccatgtatgacaccaaaacccgagagctccggtggaatgccacc
tactttgactatgcggcctcgctgcctgaggacgacgtggactacaagatgtcccacttt
gtgtccaatggtgacggactggtggtgactgtggacagtgaatctggggatgtcctgtgg
atccaaaactacgcctcccctgtggtggccttttatgtctggcagcgggagggtctgagg
aaggtgatgcacatcaatgtcgctgtggagaccctgcgctatctgaccttcatgtctggg
gaggtggggcgcatcaccaagtggaagtacccgttccccaaagagacagaggccaagagc
aagctgacgcccactctgtatgtcgggaaatactctaccagcctctatgcctctccctca
atggtacacgagggggttgctgtcgtgccccgcggcagcacacttcctttgctggaaggg
ccccagactgatggcgtcaccattggggacaagggggagtgtgtgatcacgcccagcaca
gacgtcaagtttgaccccggactcaaaagcaagaacaagctcaactacttgaggaattac
tggcttctgataggacaccatgaaaccccactgtctgcgtctaccaagatgctggagaga
tttcctaacaatctacccaaacatcgggaaaatgtgattcctgctgattcagagaaaaag
agctttgaggaagttatcaacctggttgaccagacttcagaaaacgcacctaccaccgtg
tctcgggatgtggaggagaagcctgcccatgcccctgcccggcccgaggcccccgtggac
tccatgctcaaggacatggctaccatcatcctgagcaccttcctgctgattggctgggtg
gccttcatcatcacctatcccctgagcatgcatcagcagcagcagctccagcaccagcag
ttccagaaggaactggagaagatacagctcctgcagcagcagcagcagctgcccttccac
ccaccgggagacacggctcaggacggcgagctcctggacacgtctggcccatactcagag
agctcgggcaccagcagccccagcacgtcccccagggcctccaaccactcgctctgctcc
ggcagctttgcctctaaggctggcagcagcccctccctggaacaagacgatggagatgag
gaaaccagcatggtgatagttgggaaaatttccttctgtcccaaggatgtcctgggccat
ggagctgagggcacaattgtgtaccggggcatgtttgacaaccgggacgtggccgtgaag
aggatcctaccggagtgttttagctttgcagaccgtgaggtccagctgttgcgagaatcg
gatgagcacccgaacgtgatccgctacttctgcacggagaaggaccggcaattccagtac
attgccattgagctgtgtgcagccaccctgcaagagtatgtggagcagaaggactttgcg
catctcggcctggagcccatcaccttgctgcagcagaccacctcgggcctggcccacctc
cactccctcaacatcgttcacagagacctaaagccgcataacattctcatatccatgccc
aatgcacacggcaagatcaaggccatgatctctgactttggcctctgcaagaagctggca
gtgggcagacacagtttcagccgccgatctggggtgcctggcacagaaggctggatcgct
ccggagatgctgagcgaagactgtaaggagaaccctacctacacggtggacatattttct
gcaggctgcgtcttttactacgtgatctctgagggcagccacccttttggcaagtcccta
cagcggcaggccaacatcctcctgggtgcctccagccttgactgcttgcatccagagaag
cacgaagacgtcattgcacgtgaattgatagagaagatgattgcaatggatcctcagaaa
cgcccctcagcgaagcacgtgctcaaacacccattcttctggagcctagagaagcagctc
cagttcttccaggacgtgagcgacagaatagaaaaggaatccctggatggcccgatcgtg
aagcagttagagagaggcgggagagccgtggtgaagatggactggcgggagaacatcacc
gtccccctccagacagacctgcgtaaattcaggacctataaaggtggttctgtcagagat
ctcctccgagccatgagaaacaagaagcaccactaccgggagctgcctgcggaggtgcgg
gagacactggggtccctccccgacgacttcgtgtgctacttcacatctcgcttcccccac
ctcctcgcacacacctaccaggccatggagctgtgcagccacgagagactcttccagccc
tactacttccacgagcccccagagccgcagcccccagtgactccagacgccctctga
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