Pongo pygmaeus (Bornean orangutan): 129018032
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Entry
129018032 CDS
T10128
Symbol
TOP3A
Name
(RefSeq) DNA topoisomerase 3-alpha isoform X1
KO
K03165
DNA topoisomerase III [EC:
5.6.2.1
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg03440
Homologous recombination
ppyg03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
129018032 (TOP3A)
03460 Fanconi anemia pathway
129018032 (TOP3A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ppyg03032
]
129018032 (TOP3A)
03400 DNA repair and recombination proteins [BR:
ppyg03400
]
129018032 (TOP3A)
Enzymes [BR:
ppyg01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
129018032 (TOP3A)
DNA replication proteins [BR:
ppyg03032
]
Eukaryotic type
DNA Topoisomerases
129018032 (TOP3A)
DNA repair and recombination proteins [BR:
ppyg03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
Bloom's syndrome complex (BTR)
129018032 (TOP3A)
FA (Fanconi anemia) pathway
129018032 (TOP3A)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Topoisom_bac
Zn_ribbon_GRF
Toprim
Zn_ribbon_Top1
Zn_ribbon_GRF_2
Zn_ribbon_recom
Motif
Other DBs
NCBI-GeneID:
129018032
NCBI-ProteinID:
XP_054315133
LinkDB
All DBs
Position
19:17917045..17957808
Genome browser
AA seq
1006 aa
AA seq
DB search
MIFPVVRYALRWLRRPEDRAFSRAAMEVALRGVRKVLCVAEKNDAAKGIADLLSNGRMKR
REGLSKFNKIYEFDYHLYGQNVTMVMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEK
YCPENFVDIKKTLERETRQCQALVIWTDCDREGENIGFEIVHVCKAVKPNLQVLRARFSE
ITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLIS
YGSCQFPTLGFVVERFKAIQAFVPEIFHRIKVTHNHKDGIVEFNWKRHRLFNHTACLVLY
QLCMEDPMATVVQVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYI
SYPRTETNIFPRDLNLTVLVEQQTPDPRWGAFAQSILERGGPTPRNGNKSDQAHPPIHPT
KYTNSLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDV
YPYDHWSDKILPVYEQGSRFQPSTVEMVDGETSPPKLLTEADLIALMEKHGIGTDATHAE
HIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICDGKK
DKFVVLRQQVQKYKQVFIEAVAKAKKLDEALAQYFGNGTELAQQEEIYPAMPEPIRKCPQ
CNKDMVLKTKKNGGFYLSCMGFPECRSAVWLPDSVLEASRDSSVCPVCQPHPVYRLKLKF
KRGSLPPTMPLEFVCCIGGCDDTLREILDLRFSRGPPRASQPSGRLQANQSLNRMDNSQH
PQPADSRQTAPSKALAQTLPPPTATGESNSVTCNCGQEAVLLTVRKEGPNQGRQFFKCSG
GNCNFFLWADSPNPGAGGPPASAYRPLGASLGRPPGPGIHLGGFGNPGDGSGSGTSCLCS
QPSVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENTAPGEAGRGMAIPASVFRCLP
QRLGTAERRQGRVMVGLGGVPGLPCTYFSSLDHFQQGDNCTVLIPN
NT seq
3021 nt
NT seq
+upstream
nt +downstream
nt
atgatctttcctgtcgtccgctacgcgctccggtggctgcgacggcccgaagaccgtgcc
ttttcccgcgccgccatggaggtggccctccgaggcgtgcggaaagtcctctgtgtggcc
gaaaaaaacgacgcggccaaggggatcgccgacctgctgtcaaacggtcgcatgaagcgg
agagaaggactttcaaaattcaacaagatctatgaatttgattatcacctgtatggccag
aatgttaccatggtaatgacttcggtttctggacatttactggctcatgatttccagatg
cagtttcgaaaatggcagagctgcaaccctcttgtcctctttgaagcagaaattgaaaag
tactgcccagagaattttgtagacattaagaaaactttggaacgagagactcgccagtgc
caggctctggtgatctggactgactgtgatagagaaggcgaaaacatcgggtttgagatt
gtccacgtgtgtaaggctgtaaagcccaatctgcaggtgttgcgagcccgattctctgag
atcacaccccatgccgtcaggacagcttgtgaaaacctgaccgagcctgatcagagggtg
agcgatgctgtggatgtgaggcaggagctggacctgaggattggagctgcctttactagg
ttccagaccctgcggcttcagaggatttttcctgaggtgctggcagagcagctcatcagt
tacggcagctgccagttccccacactgggctttgtggtggagcggttcaaagccattcag
gcttttgtaccagaaatcttccacagaattaaagtaactcataaccacaaagatggtatc
gtagaattcaactggaaaaggcatcgactctttaaccacactgcttgcctagttctctat
cagttgtgtatggaggatcccatggcaactgtggtacaggtcagatctaagcccaagagc
aagtggcggcctcaagctttggacactgtggagcttgagaagctggcttctcgaaagttg
agaataaatgctaaagaaaccatgaggattgctgagaagctctacactcaagggtacatc
agctatccccgaacagaaacaaacatttttcccagagacttaaacctgacggtgttggtg
gaacagcagacccccgatccacgctggggggcctttgcccagagcattctagagcggggt
ggtcccaccccacgcaatgggaacaagtctgaccaagctcaccctcccattcaccccacc
aaatacaccaacagcttacagggagatgaacagcgactgtacgagtttattgttcgccat
ttcctggcttgttgctcccaggatgctcaggggcaggagaccacagtggagatcgacatc
gctcaggaacgctttgtggcccacggcctcatgattctggcccgaaactatctggatgtg
tatccatatgatcactggagtgacaagatcctccctgtctatgagcaaggatcccgcttt
cagcccagcaccgtggagatggtggacggggagaccagcccgcccaagctgctcaccgag
gccgacctcattgccctcatggagaagcatggcattggtacggatgccactcatgcggag
cacatcgagaccatcaaagcccggatgtacgtgggcctcaccccagacaagcggttcctc
cctgggcacctgggcatgggacttgtggaaggttatgattccatgggctatgaaatgtct
aagcctgacctccgggctgaactggaagctgatctgaagctgatctgtgatggcaaaaag
gacaaatttgtggttctaaggcagcaagtgcagaaatacaagcaggttttcattgaagcg
gtggctaaagcaaagaaattggacgaggccttggcccagtactttgggaatgggacagag
ttggcccagcaagaagagatctacccagccatgccagagcccatcaggaagtgcccgcag
tgcaacaaggacatggtccttaagaccaagaagaatggcgggttctacctcagctgcatg
ggtttcccagagtgtcgctcagctgtgtggcttccggactcggtgctggaggccagcagg
gacagcagtgtgtgtccagtttgtcagccacaccctgtgtacaggttaaagttaaagttt
aagcgcggtagccttcccccgaccatgcctctggagtttgtttgctgcatcggcggatgc
gacgacaccctgagggagatcctggacctgagattttcacggggcccccccagggctagc
cagccctctggccgcctgcaggctaaccaatccctgaacaggatggacaacagccagcac
ccccagcctgctgacagcagacagactgcgccctcaaaggctctggcccagaccctccct
ccacccacagctactggtgaaagcaattctgtgacctgcaactgtggccaggaggctgtg
ctgctcactgtccgtaaggagggccccaaccagggccggcaattctttaagtgcagtgga
ggtaactgcaacttcttcctgtgggcagacagccccaatccgggagcaggagggcctcct
gcctcggcatatagacccctgggcgcctccctgggacgcccaccaggcccagggatccac
ctaggtgggtttggcaaccctggtgatggcagtggtagtggcacatcctgcctttgcagc
cagccctccgtcacacggactgtgcagaaggatggacccaacaaggggcgccagttccac
acatgtgccaagccgagagagcagcagtgtggcttcttccagtgggtcgatgagaacact
gctccaggtgaggcaggaaggggcatggcaatccctgcttcggttttcaggtgtctgcct
cagagattggggacagcagaaagaaggcaaggcagggtcatggtgggattgggaggggta
cctgggctgccttgcacctacttttcctcacttgatcactttcagcaaggtgataattgt
acagtcctcattccaaattaa
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