KEGG   Pongo pygmaeus (Bornean orangutan): 129019356
Entry
129019356         CDS       T10128                                 
Symbol
PRKACA
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit alpha isoform X1
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
ppyg  Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg01522  Endocrine resistance
ppyg04010  MAPK signaling pathway
ppyg04014  Ras signaling pathway
ppyg04020  Calcium signaling pathway
ppyg04024  cAMP signaling pathway
ppyg04062  Chemokine signaling pathway
ppyg04081  Hormone signaling
ppyg04082  Neuroactive ligand signaling
ppyg04114  Oocyte meiosis
ppyg04140  Autophagy - animal
ppyg04211  Longevity regulating pathway
ppyg04213  Longevity regulating pathway - multiple species
ppyg04261  Adrenergic signaling in cardiomyocytes
ppyg04270  Vascular smooth muscle contraction
ppyg04310  Wnt signaling pathway
ppyg04340  Hedgehog signaling pathway
ppyg04371  Apelin signaling pathway
ppyg04530  Tight junction
ppyg04540  Gap junction
ppyg04611  Platelet activation
ppyg04713  Circadian entrainment
ppyg04714  Thermogenesis
ppyg04720  Long-term potentiation
ppyg04723  Retrograde endocannabinoid signaling
ppyg04724  Glutamatergic synapse
ppyg04725  Cholinergic synapse
ppyg04726  Serotonergic synapse
ppyg04727  GABAergic synapse
ppyg04728  Dopaminergic synapse
ppyg04740  Olfactory transduction
ppyg04742  Taste transduction
ppyg04750  Inflammatory mediator regulation of TRP channels
ppyg04910  Insulin signaling pathway
ppyg04911  Insulin secretion
ppyg04912  GnRH signaling pathway
ppyg04913  Ovarian steroidogenesis
ppyg04914  Progesterone-mediated oocyte maturation
ppyg04915  Estrogen signaling pathway
ppyg04916  Melanogenesis
ppyg04918  Thyroid hormone synthesis
ppyg04919  Thyroid hormone signaling pathway
ppyg04921  Oxytocin signaling pathway
ppyg04922  Glucagon signaling pathway
ppyg04923  Regulation of lipolysis in adipocytes
ppyg04924  Renin secretion
ppyg04925  Aldosterone synthesis and secretion
ppyg04926  Relaxin signaling pathway
ppyg04927  Cortisol synthesis and secretion
ppyg04928  Parathyroid hormone synthesis, secretion and action
ppyg04934  Cushing syndrome
ppyg04935  Growth hormone synthesis, secretion and action
ppyg04961  Endocrine and other factor-regulated calcium reabsorption
ppyg04962  Vasopressin-regulated water reabsorption
ppyg04970  Salivary secretion
ppyg04971  Gastric acid secretion
ppyg04976  Bile secretion
ppyg05012  Parkinson disease
ppyg05020  Prion disease
ppyg05030  Cocaine addiction
ppyg05031  Amphetamine addiction
ppyg05032  Morphine addiction
ppyg05034  Alcoholism
ppyg05146  Amoebiasis
ppyg05163  Human cytomegalovirus infection
ppyg05165  Human papillomavirus infection
ppyg05166  Human T-cell leukemia virus 1 infection
ppyg05200  Pathways in cancer
ppyg05203  Viral carcinogenesis
ppyg05205  Proteoglycans in cancer
ppyg05207  Chemical carcinogenesis - receptor activation
ppyg05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ppyg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    129019356 (PRKACA)
   04014 Ras signaling pathway
    129019356 (PRKACA)
   04310 Wnt signaling pathway
    129019356 (PRKACA)
   04340 Hedgehog signaling pathway
    129019356 (PRKACA)
   04371 Apelin signaling pathway
    129019356 (PRKACA)
   04020 Calcium signaling pathway
    129019356 (PRKACA)
   04024 cAMP signaling pathway
    129019356 (PRKACA)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    129019356 (PRKACA)
   04081 Hormone signaling
    129019356 (PRKACA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    129019356 (PRKACA)
  09143 Cell growth and death
   04114 Oocyte meiosis
    129019356 (PRKACA)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    129019356 (PRKACA)
   04540 Gap junction
    129019356 (PRKACA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    129019356 (PRKACA)
   04062 Chemokine signaling pathway
    129019356 (PRKACA)
  09152 Endocrine system
   04911 Insulin secretion
    129019356 (PRKACA)
   04910 Insulin signaling pathway
    129019356 (PRKACA)
   04922 Glucagon signaling pathway
    129019356 (PRKACA)
   04923 Regulation of lipolysis in adipocytes
    129019356 (PRKACA)
   04912 GnRH signaling pathway
    129019356 (PRKACA)
   04913 Ovarian steroidogenesis
    129019356 (PRKACA)
   04915 Estrogen signaling pathway
    129019356 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    129019356 (PRKACA)
   04921 Oxytocin signaling pathway
    129019356 (PRKACA)
   04926 Relaxin signaling pathway
    129019356 (PRKACA)
   04935 Growth hormone synthesis, secretion and action
    129019356 (PRKACA)
   04918 Thyroid hormone synthesis
    129019356 (PRKACA)
   04919 Thyroid hormone signaling pathway
    129019356 (PRKACA)
   04928 Parathyroid hormone synthesis, secretion and action
    129019356 (PRKACA)
   04916 Melanogenesis
    129019356 (PRKACA)
   04924 Renin secretion
    129019356 (PRKACA)
   04925 Aldosterone synthesis and secretion
    129019356 (PRKACA)
   04927 Cortisol synthesis and secretion
    129019356 (PRKACA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    129019356 (PRKACA)
   04270 Vascular smooth muscle contraction
    129019356 (PRKACA)
  09154 Digestive system
   04970 Salivary secretion
    129019356 (PRKACA)
   04971 Gastric acid secretion
    129019356 (PRKACA)
   04976 Bile secretion
    129019356 (PRKACA)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    129019356 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    129019356 (PRKACA)
  09156 Nervous system
   04724 Glutamatergic synapse
    129019356 (PRKACA)
   04727 GABAergic synapse
    129019356 (PRKACA)
   04725 Cholinergic synapse
    129019356 (PRKACA)
   04728 Dopaminergic synapse
    129019356 (PRKACA)
   04726 Serotonergic synapse
    129019356 (PRKACA)
   04720 Long-term potentiation
    129019356 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    129019356 (PRKACA)
  09157 Sensory system
   04740 Olfactory transduction
    129019356 (PRKACA)
   04742 Taste transduction
    129019356 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    129019356 (PRKACA)
  09149 Aging
   04211 Longevity regulating pathway
    129019356 (PRKACA)
   04213 Longevity regulating pathway - multiple species
    129019356 (PRKACA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    129019356 (PRKACA)
   04714 Thermogenesis
    129019356 (PRKACA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129019356 (PRKACA)
   05205 Proteoglycans in cancer
    129019356 (PRKACA)
   05207 Chemical carcinogenesis - receptor activation
    129019356 (PRKACA)
   05203 Viral carcinogenesis
    129019356 (PRKACA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    129019356 (PRKACA)
   05163 Human cytomegalovirus infection
    129019356 (PRKACA)
   05165 Human papillomavirus infection
    129019356 (PRKACA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    129019356 (PRKACA)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    129019356 (PRKACA)
   05020 Prion disease
    129019356 (PRKACA)
  09165 Substance dependence
   05030 Cocaine addiction
    129019356 (PRKACA)
   05031 Amphetamine addiction
    129019356 (PRKACA)
   05032 Morphine addiction
    129019356 (PRKACA)
   05034 Alcoholism
    129019356 (PRKACA)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    129019356 (PRKACA)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    129019356 (PRKACA)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    129019356 (PRKACA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ppyg01001]
    129019356 (PRKACA)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:ppyg03019]
    129019356 (PRKACA)
   03036 Chromosome and associated proteins [BR:ppyg03036]
    129019356 (PRKACA)
Enzymes [BR:ppyg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     129019356 (PRKACA)
Protein kinases [BR:ppyg01001]
 Serine/threonine kinases: AGC group
  PKA family
   129019356 (PRKACA)
Messenger RNA biogenesis [BR:ppyg03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     129019356 (PRKACA)
Chromosome and associated proteins [BR:ppyg03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    129019356 (PRKACA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C
Other DBs
NCBI-GeneID: 129019356
NCBI-ProteinID: XP_054317711
LinkDB
Position
20:complement(14336448..14362517)
AA seq 351 aa
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML
VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV
MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT
TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
NT seq 1056 nt   +upstreamnt  +downstreamnt
atgggcaacgccgccgccgccaagaagggcagcgagcaggagagcgtgaaagaattctta
gccaaagccaaagaagattttcttaaaaaatgggaaagtcccgctcagaacacagcccac
ttggatcagtttgaacgaatcaagaccctcggcacgggctccttcgggcgggtgatgctg
gtgaaacacaaggagaccgggaaccactatgccatgaagatcctcgacaaacagaaggtg
gtgaaactgaaacagatagaacacaccctgaatgaaaagcgcatcctgcaagctgtcaac
tttccgttcctcgtcaaactcgagttctccttcaaggacaactcaaacttatacatggtc
atggagtacgtgcccggcggggagatgttctcacacctacggcggatcggaaggttcagc
gagccccatgcccgtttctacgcggcccagatcgtcctgacctttgagtatctgcactcg
ctggatctcatctacagagacctgaaaccggagaatctgctgattgaccagcagggctac
attcaggtgacagacttcggtttcgccaagcgcgtgaagggccgcacttggaccttgtgt
ggcacccctgagtacctggcccctgagattatcctgagcaaaggctacaacaaggccgtg
gactggtgggccctgggggttcttatctatgaaatggccgctggctacccgcccttcttc
gcagaccagcccatccagatctatgagaagatcgtctctgggaaggtgcggttcccttcc
cacttcagctctgacttgaaggacctgctgcggaacctcctgcaggtagatctcaccaag
cgctttgggaacctcaagaatggggtcaacgatatcaagaaccacaagtggtttgccaca
actgactggattgccatctaccagaggaaggtggaagctcccttcataccaaagtttaaa
ggccctggggatacgagtaactttgacgactatgaggaagaagaaatccgggtctccatc
aatgagaagtgtggcaaggagttttctgagttttag

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