Pongo pygmaeus (Bornean orangutan): 129020074
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Entry
129020074 CDS
T10128
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X3
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg04217
Necroptosis
ppyg04380
Osteoclast differentiation
ppyg04620
Toll-like receptor signaling pathway
ppyg04621
NOD-like receptor signaling pathway
ppyg04630
JAK-STAT signaling pathway
ppyg04658
Th1 and Th2 cell differentiation
ppyg04659
Th17 cell differentiation
ppyg05145
Toxoplasmosis
ppyg05160
Hepatitis C
ppyg05161
Hepatitis B
ppyg05162
Measles
ppyg05164
Influenza A
ppyg05165
Human papillomavirus infection
ppyg05167
Kaposi sarcoma-associated herpesvirus infection
ppyg05168
Herpes simplex virus 1 infection
ppyg05169
Epstein-Barr virus infection
ppyg05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
129020074 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
129020074 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
129020074 (TYK2)
04621 NOD-like receptor signaling pathway
129020074 (TYK2)
04658 Th1 and Th2 cell differentiation
129020074 (TYK2)
04659 Th17 cell differentiation
129020074 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
129020074 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
129020074 (TYK2)
05160 Hepatitis C
129020074 (TYK2)
05171 Coronavirus disease - COVID-19
129020074 (TYK2)
05164 Influenza A
129020074 (TYK2)
05162 Measles
129020074 (TYK2)
05168 Herpes simplex virus 1 infection
129020074 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
129020074 (TYK2)
05169 Epstein-Barr virus infection
129020074 (TYK2)
05165 Human papillomavirus infection
129020074 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
129020074 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppyg01001
]
129020074 (TYK2)
Enzymes [BR:
ppyg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
129020074 (TYK2)
Protein kinases [BR:
ppyg01001
]
Non-receptor tyrosine kinases
JAK family [OT]
129020074 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
129020074
NCBI-ProteinID:
XP_054319848
LinkDB
All DBs
Position
20:complement(10597617..10627947)
Genome browser
AA seq
1186 aa
AA seq
DB search
MPLRHWGTARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESLLTAEEVCIHI
AHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPQEP
AVYRCGPPGTEASSDQTAQGMQLLDPGSFEYLFEQGKHEFVNDVASLWDLSSEEEIHHFK
NESLGMAFLHLCHLALRHGISLEEVAKKTSFKDCIPRSFRRHIQQHSALTRLRLRNVFRR
FLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAP
TDPGPESGAGPPTHEVLVTGTGGIQWWPVQEEVNKEEGSSGSSGNPQASLSGKKAKAHKA
VGQPADRPREPLWAYFCDFRDITHVVLKERCVSIHRQDNKCLELSLPSRAAALSFVSLVD
GYFRLTADSNHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPY
RLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAG
DDCFSLRRCCLPQPGETSNLIIMRGARASTRTLNLSQLSFHRVDQKEITQLSHLGQGTRT
NVYEGRLRVEGSRDPEEGKMDDEDPLVPGREHGQELRVVLKVLDPSHHDIALAFYETASL
MSQVSHAHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASA
LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWMAP
ECLTGGPNSLSTAMDKWGFGATLLEICFDGEAPLQNRSPSEKEHFYQRQHRLPEPSCPEL
ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR
DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCAPQHRSGWKQEIDILRTLYHEHIVK
YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHAQHYIH
RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA
SDVWSFGVTLYELLTHCDSNQSPPTKFLELIGVAQGQMTVLRLTELLERGERLPRPDKCP
CEVYHFMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC
NT seq
3561 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgcgccactgggggacggccaggggcagtaagcccgttggggatggagcccag
cccatggctgccatgggaggcctgaaggtgcttctgcactgggctggtccaggcggcggg
gagccctgggtcactttcagtgagtcattgctgacagctgaggaagtctgcatccatatt
gcacataaagttggtatcactcctccttgtttcaatctcttcgccctcttcgatgctcag
gcccaagtctggttgcccccaaaccacatcctagagatccccagagatgcaagcctgatg
ctatatttccgcataaggttttatttccggaactggcatggcatgaatcctcaggaaccg
gctgtgtaccgttgtgggcccccaggaaccgaggcatcctcagatcagacagcacagggg
atgcaactcctggacccaggctcatttgagtacctctttgagcagggcaagcatgagttt
gtgaatgacgtggcatcactgtgggatctgtcgagcgaggaggagatccaccactttaag
aatgagagcctgggcatggcctttctgcacctctgtcacctcgctctccgccatggcatc
tccctggaggaggtggccaagaagaccagcttcaaggactgcatcccacgctccttccgt
cggcatatccagcagcacagtgccctgacccggctgcgccttcggaacgtcttccgcagg
ttcctgcgggacttccagccgggccgactctcccagcagatggtcatggttaaataccta
gccacacttgagcggctggcaccccgcttcggcacagagcgtgtgcccgtgtgccacctg
aggctactggcccaggccgagggggagccctgctacatccgggacagcggggtggcccct
acagaccctggccccgagtctggtgctgggcccccaacccacgaggtgctggtgactggc
actggtggcatccagtggtggccagtacaggaggaggtgaacaaggaggagggttctagt
ggcagcagtggcaacccccaagccagcctgtctgggaagaaggccaaggctcacaaggca
gtcggccagccggcggacaggccgcgggagccactgtgggcctacttctgtgacttccgg
gacatcacccacgtggtgctgaaagagcgctgtgtcagcatccaccggcaggacaacaag
tgcctggagctgagcctgccttcccgggctgcggcgctgtccttcgtgtcgctggtggac
ggctatttccgcctgacggccgactccaaccactacctgtgccacgaggtggctccccca
cggctggtgatgagcatccgggatgggatccacggacccctgctggagccatttgtgcag
gccaagctgcggcccgaggacggcctgtacctcattcactggagcaccagccacccctac
cgcctgatcctcacagtggcccagcgtagccaggcaccagacggcatgcagagcttgcgg
ctccggaagttccccattgagcagcaggacggggccttcgtgctggagggctggggccgg
tccttccccagcgttcgggaacttggggctgccttgcagggctgcttgctgagggctggg
gacgactgcttctctctgcgtcgctgttgcctgccccaaccaggagaaacctccaatctc
atcatcatgcggggggctcgggccagcaccaggacactcaacctcagccagctcagcttc
caccgcgttgaccagaaggagatcacccagctgtcccacttgggccagggcacaaggacc
aacgtgtatgagggccgcctgcgagtggagggcagcagggaccctgaggagggcaagatg
gatgacgaggaccccctcgtgcctggcagggagcatgggcaggagctacgagtggtgctc
aaagtgctggaccctagtcaccatgacatcgccctggccttctacgagacagccagcctc
atgagccaggtctcccacgcacacctggccttcgtgcatggcgtctgtgtgcgcggccct
gaaaatatcatggtgacagagtatgtggagcacggacccctggatgtgtggctgcggagg
gagcggggccatgtgcccatggcttggaagatggtggtggcccagcaactggccagcgcc
ctcagctacctggagaacaagaacctggttcatggtaatgtgtgtggccggaacatcctg
ctggcccgactggggctggcagagggcaccagccccttcatcaagctgagtgatcccggc
gtgggcctgggcgccctctccagggaggagcgggtggagaggatcccctggatggccccc
gaatgcctaacaggtgggcccaacagcctaagcaccgccatggacaagtgggggtttggc
gccaccctcttggagatctgctttgacggagaggcccctctgcagaaccgcagcccctcc
gagaaggagcatttctaccaaaggcagcaccggctgcccgagccctcctgcccagagctg
gccacactcaccagccagtgtctgacctatgagccgacccagaggccatcattccgcacc
atcctgcgtgacctcacccggctgcagccccacaatcttgctgacgtcttgactgtgaac
ccggactcaccagcctcagaccctacggttttccacaagcgctatttgaaaaagatccga
gatctgggcgagggtcacttcggcaaggtcagcttgtactgctacgatccgaccaacgac
ggcactggcgagatggtggcggtgaaagccctcaaggcagactgcgctccccagcaccgc
tccggctggaagcaggagattgacattctgcgcacgctctatcacgagcacatcgtcaag
tacaagggctgctgcgaggaccaaggcgagaagtctctgcagctggtcatggagtacgtg
cccctgggcagcctccgagactacctgccccggcacagcgtcgggctggcccagctgctg
ctcttcgcccagcagatctgcgagggcatggcctatctgcacgcgcagcactacatccac
cgagacttagccgcgcgcaacgtgctgctggacaacgacaggctggtcaagatcggggac
tttggcctagccaaggccgtgcccgaaggccacgagtactaccgcgtgcgcgaggatggg
gacagccctgtgttctggtatgccccagagtgcctgaaggagtataagttctactatgcg
tccgatgtctggtccttcggggtgaccctgtatgagctgctgacgcactgtgactccaac
cagagcccccccacgaaattccttgagctcataggcgttgctcagggtcagatgacagtt
ctgagactcaccgagttgctggaacgaggggagaggctgccacggcccgacaaatgtccc
tgtgaggtctatcatttcatgaagaactgctgggagacagaggcgtccttccgcccaacc
ttcgagaacctcatacccatcctgaagacagtccatgagaagtaccaaggccaggcccct
tcagtgttcagcgtgtgctga
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