Pongo pygmaeus (Bornean orangutan): 129022097
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Entry
129022097 CDS
T10128
Symbol
PLCB1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X2
KO
K05858
phosphatidylinositol phospholipase C, beta [EC:
3.1.4.11
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg00562
Inositol phosphate metabolism
ppyg01100
Metabolic pathways
ppyg04015
Rap1 signaling pathway
ppyg04020
Calcium signaling pathway
ppyg04022
cGMP-PKG signaling pathway
ppyg04062
Chemokine signaling pathway
ppyg04070
Phosphatidylinositol signaling system
ppyg04071
Sphingolipid signaling pathway
ppyg04072
Phospholipase D signaling pathway
ppyg04081
Hormone signaling
ppyg04082
Neuroactive ligand signaling
ppyg04261
Adrenergic signaling in cardiomyocytes
ppyg04270
Vascular smooth muscle contraction
ppyg04310
Wnt signaling pathway
ppyg04371
Apelin signaling pathway
ppyg04540
Gap junction
ppyg04611
Platelet activation
ppyg04613
Neutrophil extracellular trap formation
ppyg04621
NOD-like receptor signaling pathway
ppyg04713
Circadian entrainment
ppyg04720
Long-term potentiation
ppyg04723
Retrograde endocannabinoid signaling
ppyg04724
Glutamatergic synapse
ppyg04725
Cholinergic synapse
ppyg04726
Serotonergic synapse
ppyg04728
Dopaminergic synapse
ppyg04730
Long-term depression
ppyg04742
Taste transduction
ppyg04750
Inflammatory mediator regulation of TRP channels
ppyg04911
Insulin secretion
ppyg04912
GnRH signaling pathway
ppyg04915
Estrogen signaling pathway
ppyg04916
Melanogenesis
ppyg04918
Thyroid hormone synthesis
ppyg04919
Thyroid hormone signaling pathway
ppyg04921
Oxytocin signaling pathway
ppyg04922
Glucagon signaling pathway
ppyg04924
Renin secretion
ppyg04925
Aldosterone synthesis and secretion
ppyg04926
Relaxin signaling pathway
ppyg04927
Cortisol synthesis and secretion
ppyg04928
Parathyroid hormone synthesis, secretion and action
ppyg04929
GnRH secretion
ppyg04933
AGE-RAGE signaling pathway in diabetic complications
ppyg04934
Cushing syndrome
ppyg04935
Growth hormone synthesis, secretion and action
ppyg04961
Endocrine and other factor-regulated calcium reabsorption
ppyg04970
Salivary secretion
ppyg04971
Gastric acid secretion
ppyg04972
Pancreatic secretion
ppyg04973
Carbohydrate digestion and absorption
ppyg05010
Alzheimer disease
ppyg05016
Huntington disease
ppyg05017
Spinocerebellar ataxia
ppyg05022
Pathways of neurodegeneration - multiple diseases
ppyg05142
Chagas disease
ppyg05143
African trypanosomiasis
ppyg05146
Amoebiasis
ppyg05163
Human cytomegalovirus infection
ppyg05200
Pathways in cancer
ppyg05415
Diabetic cardiomyopathy
ppyg05417
Lipid and atherosclerosis
Module
ppyg_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
Enzymes [BR:
ppyg01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
129022097 (PLCB1)
Membrane trafficking [BR:
ppyg04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
129022097 (PLCB1)
Endocytosis
Macropinocytosis
Phospholipase C
129022097 (PLCB1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
129022097
NCBI-ProteinID:
XP_054324211
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Position
21:2686440..3435992
Genome browser
AA seq
1216 aa
AA seq
DB search
MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS
GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
KLSEQASNTYSDSSSVFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
EADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
KLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSS
EELGGDIPGKEFDTPL
NT seq
3651 nt
NT seq
+upstream
nt +downstream
nt
atggccggggctcaacccggagtgcacgccttgcaactcaagcccgtgtgcgtgtccgac
agcctcaagaagggcaccaaattcgtcaagtgggatgatgactcaactattgttactcca
attattttgaggactgaccctcagggatttttcttttactggacagatcaaaacaaggag
acggagctactggatctcagccttgtcaaagatgccagatgtgggagacacgccaaagct
cccaaggaccctaaattacgtgaacttttggatgtggggaacatcgggcgcctggagcag
cgcatgatcacagtggtgtatgggcctgacctcgtgaacatctcccatttgaatctcgtg
gctttccaagaagaagtggccaaggaatggacaaatgaggttttcagtttggcaacaaac
ctgctggcccaaaacatgtccagggatgcatttctggaaaaagcctatactaaacttaag
ctgcaagtcactccagaagggcgtattcctctcaaaaacatatatcgcttgttttcagca
gaccggaagcgagttgaaactgctttagaggcttgtagtcttccatcttcaaggaatgat
tcaatacctcaagaagatttcactccagaagtgtacagagttttcctcaacaacctttgc
cctcgacctgaaattgataacatcttttcagaatttggtgcaaaaagcaaaccatatctt
accgttgatcagatgatggattttatcaaccttaagcagcgagatcctcggcttaatgaa
atactttatccacctctaaaacaagagcaagtccaagtattgattgagaagtatgaaccc
aacaatagcctcgccagaaaaggacaaatatcagtggatgggttcatgcgctatctgagt
ggagaagaaaacggagtcgtttcacctgagaaactggatttgaatgaagacatgtctcag
ccactttctcactatttcattaattcctcgcacaacacctacctcacagctggccaactg
gctggaaactcctctgttgagatgtatcgccaagtgctcctgtctggttgtcgctgtgtg
gagctggactgctggaagggacggactgcagaagaggaacctgtcatcacccatggcttc
accatgacaactgaaatatctttcaaggaagtgatagaagcaattgcggagtgtgcattt
aagacttcaccttttccaattctcctttcatttgagaaccatgtggattccccaaagcag
caagccaagatggcggagtactgccgactgatctttggggatgcccttctcatggagccc
ctggaaaaatatccactggaatctggagttcctcttccaagccctatggatttaatgtat
aaaattttggtgaaaaataagaagaaatcacataagtcatcagaaggaagtggcaaaaag
aagctctcagaacaagcctccaacacctacagtgactcctccagcgtgttcgagccctca
tccccaggagccggagaagctgatacggaaagtgacgacgacgatgatgatgatgactgt
aaaaaatcttcaatggatgaggggaccgctggaagtgaggctatggccacagaagaaatg
tctaacctggtgaactacattcagccagtcaagtttgagtcatttgaaatttcaaaaaaa
agaaataaaagttttgaaatgtcttccttcgtggaaaccaaaggacttgaacaactcacc
aagtctccggtggaatttgtagaatataacaaaatgcagcttagcaggatatatccaaaa
ggaacacgtgtggattcatccaactatatgcctcagctcttctggaatgcaggttgtcag
atggtggcacttaatttccagacaatggacctggctatgcaaataaatatggggatgtat
gaatacaacgggaagagtggctacagattgaagccagagttcatgaggaggcctgacaag
cattttgatccatttactgaaggcatcgtagatgggatagtggcaaacactttgtctgtt
aagattatttcaggtcagtttctttctgataagaaagttgggacttacgtggaagtggat
atgtttggtttgcctgtggatacaaggaggaaggcatttaagaccaaaacatcccaagga
aatgctgtgaatcctgtctgggaagaagaacctattgtgttcaaaaaggtggttcttcct
actctggcctgtttgagaatagcagtttatgaagaaggaggtaaattcattggccaccgt
atcttgccagtgcaagccattcggccagggtatcactatatctgtctaaggaatgaaagg
aaccagcctctgacgctgcctgctgtctttgtctacatagaagtgaaagactatgtgcca
gacacatatgcagacgtcattgaagctttatcaaacccaatccgatatgtgaacctgatg
gaacagagagctaagcaattggctgctttgacactggaagatgaagaagaagtaaagaaa
gaggctgatcctggagaaacaccatcagaggctccaagtgaagcaagaacgactccagca
gaaaacggggtgaatcacaccacaaccctgacacccaaaccaccctcccaggctctccac
agccagccagctccaggttctgtaaaggcacctgccaaaacagaagatcttattcagagt
gtcttaacagaagtggaagcacagaccatcgaagaactaaagcaacagaaatcgtttgtg
aaacttcaaaagaaacactacaaagaaatgaaagacctggttaagagacaccacaagaaa
accactgaccttatcaaagaacacactaccaagtataatgaaattcagaatgactacttg
agaaggagagcagccttggaaaagtctgccaaaaaggacagtaagaaaaaatcggaaccc
agcagccctgatcatggttcatcaacgattgagcaagacctcgctgccctggatgctgaa
atgacccaaaagttaatagacttgaaggacaaacaacagcagcagctgcttaatcttcgg
caagaacagtattatagtgaaaaataccagaagcgagaacatattaaactgcttattcaa
aagttgacggatgtcgcagaagagtgtcagaacaatcagttaaagaagctcaaagaaatc
tgtgagaaagaaaagaaagaattaaagaagaaaatggataaaaagaggcaggagaagata
acagaagctaaatccaaagacaaaagtcagatggaagaggagaagacagagatgatccgg
tcatatatccaggaagtggtgcagtatatcaagaggctagaagaagcgcaaagtaaacga
caagaaaaactcgtagagaaacacaaggaaatacgtcagcagatcctggatgaaaagccc
aagctgcaggtggagctggagcaagaataccaagacaaattcaaaagactgcccctcgag
attttggaattcgtgcaggaagccatgaaaggaaagatcagtgaagacagcaatcacggt
tctgcccctctctccctgtcctcagaccctggaaaagtgaaccacaagactccctccagt
gaggaactgggaggagacatcccaggaaaagaatttgatactcctctgtga
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integrated database retrieval system
