KEGG   Pongo pygmaeus (Bornean orangutan): 129023445
Entry
129023445         CDS       T10128                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
ppyg  Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg04010  MAPK signaling pathway
ppyg04022  cGMP-PKG signaling pathway
ppyg04137  Mitophagy - animal
ppyg04141  Protein processing in endoplasmic reticulum
ppyg04151  PI3K-Akt signaling pathway
ppyg04210  Apoptosis
ppyg04211  Longevity regulating pathway
ppyg04261  Adrenergic signaling in cardiomyocytes
ppyg04668  TNF signaling pathway
ppyg04720  Long-term potentiation
ppyg04722  Neurotrophin signaling pathway
ppyg04725  Cholinergic synapse
ppyg04728  Dopaminergic synapse
ppyg04911  Insulin secretion
ppyg04912  GnRH signaling pathway
ppyg04915  Estrogen signaling pathway
ppyg04918  Thyroid hormone synthesis
ppyg04922  Glucagon signaling pathway
ppyg04925  Aldosterone synthesis and secretion
ppyg04926  Relaxin signaling pathway
ppyg04927  Cortisol synthesis and secretion
ppyg04928  Parathyroid hormone synthesis, secretion and action
ppyg04932  Non-alcoholic fatty liver disease
ppyg04934  Cushing syndrome
ppyg04935  Growth hormone synthesis, secretion and action
ppyg05010  Alzheimer disease
ppyg05012  Parkinson disease
ppyg05014  Amyotrophic lateral sclerosis
ppyg05020  Prion disease
ppyg05022  Pathways of neurodegeneration - multiple diseases
ppyg05030  Cocaine addiction
ppyg05031  Amphetamine addiction
ppyg05034  Alcoholism
ppyg05161  Hepatitis B
ppyg05163  Human cytomegalovirus infection
ppyg05166  Human T-cell leukemia virus 1 infection
ppyg05203  Viral carcinogenesis
ppyg05207  Chemical carcinogenesis - receptor activation
ppyg05215  Prostate cancer
ppyg05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ppyg00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    129023445 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    129023445 (ATF4)
   04668 TNF signaling pathway
    129023445 (ATF4)
   04022 cGMP-PKG signaling pathway
    129023445 (ATF4)
   04151 PI3K-Akt signaling pathway
    129023445 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    129023445 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    129023445 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    129023445 (ATF4)
   04922 Glucagon signaling pathway
    129023445 (ATF4)
   04912 GnRH signaling pathway
    129023445 (ATF4)
   04915 Estrogen signaling pathway
    129023445 (ATF4)
   04926 Relaxin signaling pathway
    129023445 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    129023445 (ATF4)
   04918 Thyroid hormone synthesis
    129023445 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    129023445 (ATF4)
   04925 Aldosterone synthesis and secretion
    129023445 (ATF4)
   04927 Cortisol synthesis and secretion
    129023445 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    129023445 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    129023445 (ATF4)
   04728 Dopaminergic synapse
    129023445 (ATF4)
   04720 Long-term potentiation
    129023445 (ATF4)
   04722 Neurotrophin signaling pathway
    129023445 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    129023445 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    129023445 (ATF4)
   05203 Viral carcinogenesis
    129023445 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    129023445 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    129023445 (ATF4)
   05161 Hepatitis B
    129023445 (ATF4)
   05163 Human cytomegalovirus infection
    129023445 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    129023445 (ATF4)
   05012 Parkinson disease
    129023445 (ATF4)
   05014 Amyotrophic lateral sclerosis
    129023445 (ATF4)
   05020 Prion disease
    129023445 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    129023445 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    129023445 (ATF4)
   05031 Amphetamine addiction
    129023445 (ATF4)
   05034 Alcoholism
    129023445 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    129023445 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    129023445 (ATF4)
   04934 Cushing syndrome
    129023445 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ppyg03000]
    129023445 (ATF4)
Transcription factors [BR:ppyg03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    129023445 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 DUF3450 DUF4407 Asd-4 OVT1 Nop53 DUF4192 AAA_13 KIF21A Laminin_II
Other DBs
NCBI-GeneID: 129023445
NCBI-ProteinID: XP_054326142
LinkDB
Position
23:50457413..50460012
AA seq 352 aa
MTEMSFLSSEVLVGDLMSAFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
WLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDFDALLGIDDLETMPDDLLTTLDDTC
DLFAPLVQETNKEPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPVSPGVLSSTPDHSFSL
ELGSEVDITEGDRKPDSTAYVITMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTR
GSPNRSLPSAGVLCGSGRPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQKK
RAEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP
NT seq 1059 nt   +upstreamnt  +downstreamnt
atgaccgaaatgagcttcctgagcagcgaggtgttggtgggggacttgatgtccgccttc
gaccagtcgggtttgggggctgaagaaagcctaggtctcttagatgactatctggaggtg
gccaagcacttcaaacctcatgggttctccagcgacaaggctaaggcgggctcctccgaa
tggctggctgtggatgggttggtcagtccctccaacaacagcaaggaggatgccttctcc
gggacagattggatgttggagaaaatggatttgaaggagttcgactttgatgccctgttg
ggtatagatgatctggaaaccatgccagatgaccttttgaccacgttggatgacacttgt
gatctctttgcccctctagtccaggagactaataaggagcccccccagacagtgaaccca
attggccatctcccagaaagtttaacaaaacccgaccaggttgcccccttcaccttcttg
caacctcttcccgtttccccaggggtcctgtcctccactccagatcattcctttagttta
gagctgggcagtgaagtggatatcactgaaggagataggaagccagactccactgcttat
gttattaccatgatccctcagtgcataaaggaggaagacaccccttcagataatgatagt
ggcatctgtatgagcccagagtcctatctggggtctcctcagcatagcccctctaccagg
ggctctccaaataggagcctcccatctgcaggtgttctctgtgggtctgggcgccccaaa
ccttacgatcctcctggagagaagatggtagcagcaaaagtaaagggtgagaagctggat
aagaagctgaaaaaaatggagcaaaacaagacagcagccactaggtaccgccagaagaag
agggcggagcaggaggctctcactggagagtgtaaagagctggaaaagaagaacgaggct
ctaaaagagagggcggattccctggccaaggagatccagtacctgaaagatttgatagaa
gaggtccgcaaggcaagggggaagaaaagggtcccctag

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