Pongo pygmaeus (Bornean orangutan): 129030203
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Entry
129030203 CDS
T10128
Symbol
TPO
Name
(RefSeq) thyroid peroxidase isoform X1
KO
K00431
thyroid peroxidase [EC:
1.11.1.8
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg00350
Tyrosine metabolism
ppyg01100
Metabolic pathways
ppyg04918
Thyroid hormone synthesis
ppyg05320
Autoimmune thyroid disease
Module
ppyg_M00043
Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
129030203 (TPO)
09150 Organismal Systems
09152 Endocrine system
04918 Thyroid hormone synthesis
129030203 (TPO)
09160 Human Diseases
09163 Immune disease
05320 Autoimmune thyroid disease
129030203 (TPO)
Enzymes [BR:
ppyg01000
]
1. Oxidoreductases
1.11 Acting on a peroxide as acceptor
1.11.1 Peroxidases
1.11.1.8 iodide peroxidase
129030203 (TPO)
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Gene cluster
GFIT
Motif
Pfam:
An_peroxidase
EGF_CA
FXa_inhibition
EGF_3
Sushi
cEGF
EGF
Motif
Other DBs
NCBI-GeneID:
129030203
NCBI-ProteinID:
XP_054331209
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All DBs
Position
12:complement(132605743..132732686)
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AA seq
936 aa
AA seq
DB search
MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVASILEESKRLVDTAMYATMQR
NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRNVNLKTQQSQHPTDALS
EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRLITGACNNRDHPRWGASNTALARWLPPV
YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDHYSDLLMAWGQYIDHD
IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACSTGD
QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHASLRDSG
RAYLPFAPPRAPAACAPEPGVPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA
LKTLNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT
VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIR
GLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGL
PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ
MKALRDGDWFWWENSHVFTDAQRHELEKHSLSRVICDNTGLTRVPVDAFQVGKFPEDFES
CDSIPGMNLEAWRETFPQDDKCGFPENVENGDFVHCEESGRRMLVYSCWHGYELQGREQL
TCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD
SGRLPRATWVSISLAALLIGGLAGLTSTVICRWTRAGTKSTLPISETGGGTPQLRCGKHR
DAGTSPQQAAAQDSEQESAGILKGCREPSEGKVAGH
NT seq
2811 nt
NT seq
+upstream
nt +downstream
nt
atgagagcgcttgctgtcctgtctgtcacgctggttatggcctgcacagaagccttcttc
cctttcatctcgagagggaaagaactcctttggggaaagcctgaggagtctcgtgttgcc
agcatcttggaggaaagcaagcgcctggtggacaccgccatgtacgccacgatgcagaga
aacctcaaaaaaagaggaatcctttctccagctcagcttctgtctttttccaaacttcct
gagccaacaagtggagtgattgcccgagcagcagagataatggaaacatcaatacaagcg
atgaaaagaaacgtcaacctgaaaactcaacaatcacagcatccaacggatgctttatca
gaagatctgctgagcatcattgcaaacatgtccggatgtctcccttacatgctgccccca
aaatgcccaaacacttgcctggcaaacaaatacaggctcatcacgggagcttgcaacaac
agagaccaccccagatggggcgcctccaacacggccctggcacgatggctccctccagtc
tacgaggatggcttcagtcagccccgaggctggaaccccggcttcttgtacaacgggttc
ccactgcccccggtccgggaggtgacaagacatgtcattcaagtttcaaatgaggttgtc
acagatgatgaccactattctgacctcctgatggcatggggacaatacatcgaccacgac
atcgcgttcacaccacagagcaccagcaaagctgccttcgggggaggggctgactgccag
atgacttgtgagaaccaaaacccatgttttcccatacaactcccggaggaggcccggccg
gccgcgggcaccgcctgtctgcccttctaccgctcttcggccgcctgcagcaccggggac
caaggcgcgctctttgggaacctgtccacggccaacccacggcagcagatgaacgggttg
acctcattcctggacgcgtccaccgtgtatggcagctccccggccctagagaggcagctg
cggaactggaccagtgccgaagggctgctccgcgtccacgcgagcctccgggactccggc
cgcgcctacctgcccttcgcgccgccacgcgcgcctgcggcctgtgcgcccgagcccggc
gtccccggagagacccgcgggccctgcttcctggccggagacggccgcgccagcgaggtc
ccctccctgacggcgctgcacacgctgtggctgcgcgagcacaaccgcctggccgcggcg
ctcaagaccctcaatgcgcactggagcgcggacgccgtgtaccaggaggcgcgcaaggtc
gtgggcgctctgcaccagatcatcaccctgagggattacatccccagaatcctgggaccc
gaggccttccagcagtacgtgggtccctatgaaggctatgactccacggccaaccccact
gtgtccaacgtgttctccacagccgccttccgcttcggccacgccacgatccacccactg
gtgaggaggctggacgccagcttccaagagcaccccgacctgcccgggctgtggctgcac
caggccttcttcagcccatggacactcctccgtggaggtggtttggacccactaatacga
ggccttcttgcaagaccagccaaactgcaggtgcaggatcagctcatgaacgaggagctg
acggaaaggctgtttgtgctgtccaattctagcaccttggatctggcgtccatcaacctg
cagaggggccgggaccacgggctgccaggttacaatgagtggagggagttctgtggcctg
cctcgcctggagacccccgctgacctgagcacagccattgccagcaggagcgtggccgac
aagatcctggacttgtacaagcatcctgacaacatcgatgtctggctgggaggcttagct
gaaaacttcctccccagggctcggacagggcccctgtttgcctgtctcattgggaagcag
atgaaggctctgcgggacggtgactggttttggtgggagaacagccacgtcttcacggat
gcacagaggcatgagctggagaagcactccctgtctcgggtcatctgtgacaacaccggc
ctcaccagggtgcccgtggacgccttccaagttggaaaattccccgaagactttgagtct
tgtgacagcatccctggcatgaacctggaggcctggagggaaacctttcctcaagacgac
aagtgtggcttcccagagaacgtggagaatggggactttgtgcactgtgaggagtctggg
aggcgcatgctggtgtattcctgctggcatgggtatgagctccaaggccgggagcagctc
acttgcacccaggaaggatgggatttccagcctcccctctgcaaagatgtgaacgagtgt
gcagacggtgcccaccccccctgccacgcctccgcgaggtgcagaaacaccaagggcggc
ttccagtgcctctgcgcggacccctacgagttaggagacgatgggagaacctgcgtagat
tctgggaggctccctcgggcaacttgggtctccatctcgctggctgctctgctgatcgga
ggcttggcaggtctcacctcgacggtgatttgcaggtggacacgtgctggcactaaatcc
acactgcccatctcggagacaggcggaggaactccccagctgagatgcgggaagcaccgg
gacgcaggaacctcaccgcagcaggccgcagctcaggactcggagcaggagagtgctggg
atactcaaaggctgccgagagccctctgagggcaaagtggcaggacactga
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