Pongo pygmaeus (Bornean orangutan): 129033021
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Entry
129033021 CDS
T10128
Symbol
MYLK
Name
(RefSeq) myosin light chain kinase, smooth muscle isoform X1
KO
K00907
myosin-light-chain kinase [EC:
2.7.11.18
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg04020
Calcium signaling pathway
ppyg04022
cGMP-PKG signaling pathway
ppyg04270
Vascular smooth muscle contraction
ppyg04371
Apelin signaling pathway
ppyg04510
Focal adhesion
ppyg04611
Platelet activation
ppyg04810
Regulation of actin cytoskeleton
ppyg04921
Oxytocin signaling pathway
ppyg04971
Gastric acid secretion
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
129033021 (MYLK)
04020 Calcium signaling pathway
129033021 (MYLK)
04022 cGMP-PKG signaling pathway
129033021 (MYLK)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
129033021 (MYLK)
09142 Cell motility
04810 Regulation of actin cytoskeleton
129033021 (MYLK)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
129033021 (MYLK)
09152 Endocrine system
04921 Oxytocin signaling pathway
129033021 (MYLK)
09153 Circulatory system
04270 Vascular smooth muscle contraction
129033021 (MYLK)
09154 Digestive system
04971 Gastric acid secretion
129033021 (MYLK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppyg01001
]
129033021 (MYLK)
Enzymes [BR:
ppyg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.18 myosin-light-chain kinase
129033021 (MYLK)
Protein kinases [BR:
ppyg01001
]
Serine/threonine kinases: CAMK group
MLCK family
129033021 (MYLK)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
I-set
Ig_3
ig
Ig_2
Pkinase
23ISL
V-set
PK_Tyr_Ser-Thr
C2-set_2
fn3
Ig_4
Ig_DSCAM-DSCAML_C
Invasin_D3
Kinase-like
Kdo
DUF5898
Ig_J_second
AvrM_N
Motif
Other DBs
NCBI-GeneID:
129033021
NCBI-ProteinID:
XP_054336885
LinkDB
All DBs
Position
2:complement(56397027..56677383)
Genome browser
AA seq
1914 aa
AA seq
DB search
MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP
EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE
LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVMVKEGQMGRF
SCKITGRPQPQVTWLKGNVPLQPSARVSMSEKNGMQVLEIHGVSQDDVGVYTCLVVNGSG
KASMSAELSIQGLDSANRSFGRETKATNSDVRKEVTNVISKESKLDSLEAAAESKNCSSP
QRGGSPPWAANSQPQPPRESKLESYKDSPRMAPQTPVLQKTSSSITLQAARVQPEPRAPG
LGVLSPSGEERKSPAAPRPATFPTRQPGLGSQDVVSKAATRRIPIEGQRNSAFPKFESKP
QSQEVRENQTVKFRCEVSGTPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR
DSGKYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCTVIEGQDFVLQCSIQGT
PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAKNALGQVSCSARVTV
REKKSSGKSKYLLPVAPNKPTAPVFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG
NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAMLTVQEPHDGTQ
PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV
LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG
GGSDRCGSLRPGWPARGQGWPEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL
LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK
GTPKTPVPEKVPLPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS
GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDETLKSASKEELKKDVKNDVNCKRG
RAGTTDNEKRSESQGTAPAFKEKLQDVRVAEGKKLLLQCQVSSDPPATITWTLNGKTLKT
TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE
MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK
VTGTQPITCTWMKFRKQIQESEHMKVESSENGSKLTILAARQEHCGCYTLLVENKLGSRQ
AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKMWKE
LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD
DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKQTRKVWAGKFFKAYSA
KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER
ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV
LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF
DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM
ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV
AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD
EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
NT seq
5745 nt
NT seq
+upstream
nt +downstream
nt
atgggggatgtgaaactggttgcctcgtcacacatttccaaaacctccctcagtgtggat
ccctcaagagttgactccatgcccctgacagaggcccctgctttcattttgccccctcgg
aacctctgcatcaaagaaggagccaccgccaagttcgaagggcgggtccggggttaccca
gagccccaggtgacatggcacagaaacgggcaacccatcaccagcgggggccgcttcctg
ctggattgtggcatccgggggactttcagccttgtgattcatgctgtccatgaggaggac
aggggaaagtatacctgtgaagccaccaatggcagtggtgctcgccaggtgacagtggag
ttgacagtagaaggaagttttgcgaagcagcttggtcaacctgttgtttccaaaacctta
ggggatagattttcagctccagcagtggagactcgtcctagcatctggggggagtgccca
ccaaagtttgctaccaagctgggccgagttatggtcaaagaaggacagatgggacgattc
tcctgcaagatcactggccgaccccaaccgcaggtcacctggctcaagggaaatgttcca
ctgcagccgagtgcccgtgtgtctatgtctgagaagaatgggatgcaggttctggaaatc
catggagtcagccaagatgatgtgggagtgtacacgtgcctggtggtgaacgggtcgggg
aaggcctcaatgtcagctgaactttccatccaaggtttggacagcgccaataggtcattt
gggagagaaacaaaagccaccaattcagatgtcaggaaagaggtgaccaatgtaatctca
aaggagtcaaagctggacagtctggaggctgcagccgaaagcaagaactgctccagcccc
cagagaggtggctccccaccctgggctgcaaacagccagcctcagcccccaagggagtcc
aagctggagtcatacaaggactcgcccagaatggccccgcagaccccggtccttcagaag
acttccagctccatcaccctgcaggccgcaagagttcagccagaaccaagagcaccaggc
ctgggggtcctatcaccttctggagaagagaggaagagcccagctgctccccgtccagcc
accttccccaccaggcagcctggcctggggagccaagacgttgtgagcaaggctgctacc
aggagaatccccatagagggccagaggaattcagcattccccaaatttgagagcaagccc
caaagccaggaggtcagggaaaatcaaactgtcaagttcagatgtgaagtttccgggact
ccaaagcctgaagtggcctggttcctggaaggcacccccgtgaggagacaggaaggcagc
attgaggtttatgaagatgctggctcccattacctctgcctgctgaaagcccggaccagg
gacagtgggaaatacagctgcactgcttccaacgcccaaggccaggtgtcctgtagctgg
accctccaagtggaaaggcttgccgtgatggaggtggccccctccttctccagtgtcctg
aaggactgcaccgtcattgagggccaggattttgtgctgcagtgctccatacaggggacc
ccagtgccccggatcacttggctgctgaatgggcagcccatccagtacgctcgttccacc
tgtgaggccggcgtggctgagctccacatccaggatgccctgccggaggaccatggcacc
tacacctgcctggctaagaatgccttggggcaggtgtcctgcagcgcccgggtcaccgtc
cgtgaaaagaagagtagcgggaagagcaagtaccttctgcctgtggctcccaacaagccc
actgcacccgtattcctgcagggcctctctgatctcaaagtcatggatggaagccaggtc
actatgactgtccaagtgtcagggaatccaccccctgaagtcatctggctgcacaatggg
aatgagatccaagagtcagaggacttccactttgaacagagaggcactcagcacagcctt
tgtatccaggaagtgttcccagaggacacaggcacgtacacctgcgaggcctggaacagc
gctggagaggtccgcacccaggccatgctcacggtacaagagcctcacgatggcacccag
ccctggttcatcagtaagcctcgctcagtgacagcctccctgggccagagtgtcctcatc
tcctgcgccatagctggtgacccctttcctaccgtgcactggctccgagatggcaaagcc
ctctgcaaagacactggccacttcgaggtgcttcagaatgaggacgtgttcaccctggtt
ctaaagaaggtgcagccctggcatgccggccagtatgagatcctgctcaagaaccgggtt
ggcgaatgcagttgccaggtgtcactgatgttacagaacagctctgccagagcccttcca
cgggggagggagcctgccagctgtgaggacctctgtggtggaggagttggtgctgatggt
ggtggtagtgaccgctgtgggtccctgaggcctggctggccagcaagagggcagggttgg
ccagaggaggaagacggcgaggacgtgcgaggggtgctgaagaggcgcgtggagacgagg
cagcacactgaggaggcgatccgtcagcaggaggtggagcagctggacttccgagacctc
ctggggaagaaggtgagtaccaagaccctatcagaagacgacctgaaggagatcccagcc
gagcagatggatttccgtgccaacctgcagcggcaagtgaagccaaagactgtgtccgag
gaagagaggaaggtgcacagcccccagcaggtcgatttccgctctgtcctggccaagaag
gggactcccaagacccccgtgcctgagaaggtgccactgccaaaacctgccaccccggat
tttcgctcagtgctgggtggcaagaagaaattaccagcagagaatggtagcagcagtgct
gagaccctgaacgccaaggcagtggaaagttccaagcccctgagcaatgcacagccttca
gggcccttgaaacccgtaggcaatgccaagcctgctgagaccctgaagccaatgggcaac
gccaagcctgctgagaccctgaagccaatgggcaacgccaagcctgatgagaccctgaaa
tctgctagcaaagaagaactcaagaaagatgttaagaatgatgtgaactgcaagagaggc
cgtgcagggaccacagataatgaaaagagatcagagagccaggggacagccccagccttc
aaggagaagctgcaagatgttcgtgtggcagagggcaagaagctgctgctccagtgccag
gtgtcttctgaccccccagccaccatcacctggacgctgaatggaaagaccctcaagacc
accaagttcatcatcctctcccaggaaggctcactctgctccgtctccatcgagaaggca
ctgcctgaggacagaggcttatacaagtgtgtagccaagaatgacgctggccaggctgag
tgctcctgccaagtcactgtggacgatgctccagccagtgagaacaccaaggccccagag
atgaaatcccggaggcccaagagctctcttcctcccgtgctaggaactgagagtgatgcg
actgtgaaaaagaaacctgcccccaagacacctccaaaggcagcaatgccccctcagatc
atccagttccccgaggaccagaaggtacgcgcaggagagtcagtggagctgtttggtaaa
gtgacaggcactcagcccatcacctgtacctggatgaagttccgaaagcagatccaggaa
agcgagcacatgaaggtggagagcagcgagaatggcagcaagctcaccatcctggccgcg
cgccaggagcactgcggctgctacacactgctggtggagaacaagctgggcagcaggcag
gcccaggtcaacctcactgtcgtggataagccagaccccccagctggcacaccttgtgcc
tctgacattcggagctcctcactgaccctgtcctggtacggctcctcatatgatgggggc
agcgctgtacagtcctacagcatcgagatctgggactcagccaacaagatgtggaaggaa
ctagccacatgccgcagcacctctttcaacgtccaggacctgctgcctgaccacgaatat
aagttccgtgtacgtgcaatcaatgtgtatggaaccagtgagccaagccaggagtctgaa
ctcacaacggtaggagagaaacctgaagagccgaaggatgaagtggaggtgtcagacgat
gatgagaaggagcccgaggttgattaccggacagtgacaatcaatactgaacaaaaagta
tctgacttctacgacattgaagagagattaggatctgggaaatttggacaggtctttcga
cttgtagaaaaacaaactcgaaaagtctgggcagggaagttcttcaaagcatattcagca
aaagagaaagagaatatccggcaggagatcagcatcatgaactgcctccaccaccccaag
ctggtccagtgtgtggatgccttcgaagaaaaggccaacatcgtcatggtcctggagatc
gtgtcaggaggtgagctgtttgagcgcatcattgacgaggactttgagctgacggagcgc
gagtgcatcaagtacatgcggcagatctcagagggggtggagtacatccacaagcagggc
atcgtgcacctggacctcaagccggagaacatcatgtgtgtcaacaagacgggcaccagg
atcaagctcatcgactttggtctggccaggaggctggagaacgcggggtctctgaaggtc
ctctttggcaccccggagtttgtggctcctgaagtgatcaactatgagcccatcggctac
gccacagacatgtggagcatcggggtcatctgctacatcctagtcagtggcctttccccc
ttcatgggagacaacgataatgaaaccttggccaacgttacgtcagccacctgggacttc
gacgacgaggcattcgatgagatctccgacgatgccaaggatttcatcagcaatctgctg
aagaaagatatgaaaaaccgcctggactgcacgcagtgccttcagcatccatggctaatg
aaagataccaagaacatggaggccaagaaactctccaaggacaggatgaagaagtacatg
gcaagaaggaaatggcagaaaacgggcaatgctgtgagagccattggaagactgtcctct
atggcaatgatctcagggctcagtggcaggaaatcctcaacagggtcaccaaccagcccg
ctcaatgcagaaaaactagaatctgaagaagatgtgtcccaagctttccttgaggctgtt
gctgaggaaaagcctcatgtaaaaccctatttctctaagaccattcgtgatttagaagtc
gtggagggaagtgctgctagatttgactgcaagattgaaggatacccggaccctgaggtt
gtctggttcaaagacgaccagtcaatcagggagtcccgccacttccagatagactacgat
gaggacgggaactgctctttaattattagtgatgtttgcggggatgacgatgccaagtac
acctgcaaggctgtcaacagtcttggagaagccacctgcacagcagagctcattgtggaa
acgatggaggaaggcgaaggggaaggggaagaggaagaagagtga
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integrated database retrieval system
