Pongo pygmaeus (Bornean orangutan): 129033905
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Entry
129033905 CDS
T10128
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
129033905 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ppyg03032
]
129033905 (TOP2B)
03036 Chromosome and associated proteins [BR:
ppyg03036
]
129033905 (TOP2B)
Enzymes [BR:
ppyg01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
129033905 (TOP2B)
DNA replication proteins [BR:
ppyg03032
]
Eukaryotic type
DNA Topoisomerases
129033905 (TOP2B)
Chromosome and associated proteins [BR:
ppyg03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
129033905 (TOP2B)
Centrosome formation proteins
Centriole proteins
129033905 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Motif
Other DBs
NCBI-GeneID:
129033905
NCBI-ProteinID:
XP_054339064
LinkDB
All DBs
Position
2:128222573..128289359
Genome browser
AA seq
1626 aa
AA seq
DB search
MAKSGGCGAGAGVGGGNGALTWVTLFDQNNAAKKEESETANKNDSSKKLSVERVYQKKTQ
LEHILLRPDTYIGSVEPLTQFMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRD
KNMTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVT
GGRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITF
QPDLSKFKMEKLDKDIVALMTRRAYDLAGSCRGVKVMFNGKKLPVNGFRSYVDLYVKDKL
DETGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIE
VVKKKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFF
KAASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLIL
TEGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYK
KSYDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVK
ASKNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFR
YAGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFI
NKELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHH
GEQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFP
AVDDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRM
LDGLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQV
LEPMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNS
MVLFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKI
QGKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSG
PDFNYILNMSLWSLTKEKVEELIKQRDAKGRDVNDLKRKSPSDLWKEDLAAFVEELDKVE
SQEREDILAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKK
KKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSAPMNKGPKPKREKKEPGTRVRKTPTS
SGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDD
DADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKK
SQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPS
SDTAPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNP
GRKTSKTTSKKPKKTSFDQDSDVDIFPSEFPTEPPSLPRTGRARKEVKYFAESDEEEEDV
DFAMFN
NT seq
4881 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtcgggtggctgcggcgcgggagccggcgtgggcggcggcaacggggcactg
acctgggtgactctttttgatcagaacaatgctgcaaaaaaagaagagtcagaaactgcc
aacaaaaatgattcttcaaagaagttgtctgttgagagagtgtatcagaagaagacacaa
cttgaacacattcttcttcgtcctgatacatacattgggtcagtggagccattgacgcag
ttcatgtgggtgtatgatgaagatgtaggaatgaattgcagagaggttacctttgtgcca
ggtttatacaagatctttgacgaaattttggttaatgctgctgacaataaacagagggat
aagaacatgacttgtattaaagtttctattgatcctgaatctaacattataagcatttgg
aataatgggaaaggcattccagtagtagaacacaaggtagagaaagtttatgttcctgct
ttaatttttggacagcttttaacatccagtaactatgacgatgatgagaaaaaagttaca
ggtggtcgtaatggttatggtgcaaaactttgtaatattttcagcacaaagtttacagta
gaaacagcttgcaaagaatacaaacacagttttaagcagacatggatgaataatatgatg
aagacttctgaagccaaaattaaacattttgatggtgaagattacacatgcataacattc
caaccagatctgtccaaatttaagatggaaaaacttgacaaggatattgtggccctcatg
actagaagggcatatgatttggctggttcatgtagaggggtcaaggtcatgtttaatgga
aagaaattgcctgtaaatggatttcgcagttatgtagatctttatgtgaaagacaaattg
gatgaaactggggtggccctgaaagttattcatgagcttgcaaatgaaagatgggatgtt
tgtctcacattgagtgaaaaaggattccagcaaatcagctttgtaaatagtattgcaact
acaaaaggtggacggcacgtggattatgtggtagatcaagttgttggtaaactgattgaa
gtagttaagaaaaagaacaaagctggtgtatcagtgaaaccatttcaagtaaaaaaccat
atatgggtttttattaattgccttattgaaaatccaacttttgattctcagactaaggaa
aacatgactctgcagcccaaaagttttgggtctaaatgccagctgtcagaaaaatttttt
aaagcagcctctaattgtggcattgtagaaagtatcctgaactgggtgaaatttaaggct
cagactcagctgaataagaagtgttcatcagtaaaatacagtaaaatcaaaggtattccc
aaactggatgacgctaatgatgctggtggtaaacattccctggagtgtacactgatatta
acagagggagactctgccaaatcactggctgtgtctggattaggtgtgattggacgagac
agatacggagtttttccactcaggggcaaaattcttaatgtacgggaagcttctcataaa
cagatcatggaaaatgctgaaataaataatattattaaaatagttggtctgcaatataag
aaaagttacgatgatgcagaatctctgaaaaccttacgctatggaaagattatgattatg
accgatcaggatcaagatggttctcacataaaaggcctgcttattaatttcatccatcac
aattggccatcacttttgaagcatggttttctcgaagagttcattactcctattgtaaag
gcaagcaaaaataagcaggaactttccttctacagtattcctgaatttgatgaatggaaa
aaacatatagaaaaccagaaagcctggaaaataaagtactataaaggattgggtactagt
acagctaaagaggcaaaggaatattttgctgatatggaaaggcatcgcatcttgtttaga
tatgctggtcctgaagatgatgctgccattaccttggcatttagtaagaagaagattgat
gacagaaaagaatggttaacaaattttatggaagaccggagacagcgtaggctacatggc
ttaccagagcaatttttatatggtactgcaacaaagcatttgacttataatgatttcatc
aacaaggaattgattctcttctcaaactcagacaatgaaagatctataccatctcttgtt
gatggctttaaacctggccagcggaaagttttatttacctgtttcaagaggaatgataaa
cgtgaagtaaaagttgcccagttggctggctctgttgctgagatgtcggcttatcatcat
ggagaacaagcattgatgatgactattgtgaatttggctcagaactttgtgggaagtaac
aacattaacttgcttcagcctattggtcagtttggaactcggcttcatggtggcaaagat
gctgcaagtcctcgttatattttcacaatgttaagctctttagcaaggctactttttcct
gctgtggatgacaacctccttaagttcctttatgatgataatcaacgtgtagagcctgag
tggtatattcctataattcccatggttttaataaatggtgctgagggcattggtactgga
tgggcttgtaaactacccaactatgatgctagggaaattgtgaacaatgtcagacgaatg
ctagatggcctggatcctcatcccatgcttccaaactacaaaaactttaaaggcacgatt
caagaacttggtcaaaaccagtatgcagtcagtggtgaaatatttgtagtggacagaaac
acagtagaaattacagagcttccagttagaacttggacacaggtatataaagaacaggtt
ttagaacctatgctaaatggaacagacaaaacaccagcgttaatttctgattataaagaa
tatcatactgacacaactgtgaaatttgtggtgaaaatgactgaagagaaactagcacaa
gcagaagctgctggactgcataaagtttttaaacttcaaactactcttacttgtaattcc
atggtactctttgatcatatgggatgtctgaagaaatatgaaactgtgcaagacattctg
aaagaattctttgatttacgattaagttattacggtttacgtaaggagtggcttgtggga
atgttgggagcagaatctacaaagcttaacaatcaagcccgtttcattttagagaagata
caagggaaaattactatagagaataggtcaaagaaagatttgattcaaatgttagtccag
agaggttatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaa
gaggatgaaacacaaaaccagcatgatgatagttcctccgattcaggaactccttcaggc
ccagattttaattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaa
gaactgattaaacagagagatgcaaaagggcgagatgtcaatgatcttaaaagaaaatct
ccttcagatctttggaaagaagatttagcagcatttgttgaagaattggataaagtggaa
tctcaagaacgagaagatattctggctggaatgtctggaaaagcaattaaaggtaaagtt
ggcaaacctaaggtgaagaaactccagttggaagagacaatgccctcaccttatggcaga
agaataattcctgaaattacagctatgaaggcagatgccagcaaaaagttgctgaagaag
aagaagggtgatcttgatactgcagcagtaaaagtggaatttgatgaagaattcagtgga
gcgccagtagaaggtgcaggagaagaggcattgactccatcagctcctatgaataaaggc
cccaaacccaaaagggagaagaaggagcctggtaccagagtgagaaaaacacctacatca
tctggtaaacctagtgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatcc
aagtcagaaagtgatttggaagaaacagaacctgtggttattccaagagattctttgctt
aggagagcagcagccgaaagacctaaatacacatttgatttctcagaagaagaggatgat
gatgctgatgatgatgatgatgacaataatgatttagaggaattgaaagttaaagcatct
cccataacaaatgatggggaagatgaatttgttccttcagatgggttagataaagatgaa
tatacattttcaccaggcaaatcaaaagccactccagaaaaatctttgcatgacaaaaaa
agtcaggattttggaaatctcttctcatttccttcatattctcagaagtcagaagatgat
tcagctaaatttgacagtaatgaagaagattctgcttctgttttttcaccatcatttggt
ctgaaacagacagataaagttccaagtaaaacagtagctgctaaaaagggaaaaccgtct
tcagatacagcccctaagcccaagagagccccaaaacagaagaaggtagtagaggctgta
aactctgactcggattcagaatttggcattccaaagaagactacaacaccaaaaggtaaa
ggccgaggggcaaagaaaaggaaagcatctggctctgaaaatgaaggcgattataaccct
ggcaggaaaacatccaaaacaacaagcaagaaaccgaagaagacatcttttgatcaggat
tcagatgtggacatcttcccctcagagttccctactgagccaccttctctgccacgaacc
ggtcgggctaggaaagaagtaaaatattttgccgagtctgatgaagaagaagaagacgtt
gattttgcaatgtttaattaa
DBGET
integrated database retrieval system
