Pongo pygmaeus (Bornean orangutan): 129035556
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Entry
129035556 CDS
T10128
Symbol
PDE5A
Name
(RefSeq) cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1
KO
K13762
cGMP-specific 3',5'-cyclic phosphodiesterase [EC:
3.1.4.35
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg00230
Purine metabolism
ppyg01100
Metabolic pathways
ppyg04022
cGMP-PKG signaling pathway
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
129035556 (PDE5A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
129035556 (PDE5A)
Enzymes [BR:
ppyg01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
129035556 (PDE5A)
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Motif
Pfam:
PDEase_I
GAF
GAF_2
HD-CE
DUF6970
Motif
Other DBs
NCBI-GeneID:
129035556
NCBI-ProteinID:
XP_054342044
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Position
3:complement(132063247..132197255)
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AA seq
875 aa
AA seq
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MERAGPSFGRQLLQQQPQQQKQQQRDQDSVEAWLDDHWDFTFSYFVRKATREMVNAWFAE
RVHTIPVCKEGIRGHTESCSCPLQQSPRADNSAPGTPTRKISASEFDRPLRPIVVKDSEG
TVSFLSDSEKKEQMPLTPPRFDHDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLI
SADRYSLFLVCEDSSNDKFLISRLFDVAEGSTLEEASNNCIRLEWNKGIVGHVAALGEPL
NIKDAYEDPRFNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDE
KDFAAYLAFCGIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIIS
FMQVQKCTIFIVDEDCSDSFSSVFHMECEELEKSSDTITREHDANKINYMYAQYVKNTME
PLNIPDVSKDKRFPWTTENTGNVNQQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGK
VKPFNRNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETREL
QSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWIL
SVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGV
NNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAI
LATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAE
LVATEFFDQGDRERKELNIEPTDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCF
PLLDGCRKNRQKWQALAEQQEKMLINGESGQAKRN
NT seq
2628 nt
NT seq
+upstream
nt +downstream
nt
atggagcgggccggccccagcttcgggcggcagctactgcagcagcagccccagcagcag
aagcagcagcagagggatcaggactcggtcgaagcatggctggacgatcactgggacttt
accttctcatactttgttagaaaagccaccagagaaatggtcaatgcatggtttgctgag
agagttcacaccatccctgtgtgcaaggaaggtatcagaggccacaccgaatcttgctct
tgtcccttgcagcagagtcctcgtgcagataacagtgcccctggaacaccaaccaggaaa
atctctgcctctgaatttgaccggcctcttagacccattgttgtcaaggattctgaggga
actgtgagcttcctctctgactcagaaaagaaggaacagatgcctctaacccctccaagg
tttgatcatgatgaaggggaccagtgctcaagactcttggaattagtgaaggatatttct
agtcatttggatgtcacagccttatgtcacaaaattttcttgcatatccatggactcatc
tctgctgaccgctattccctgttccttgtctgtgaagacagctccaatgacaagtttctt
atcagccgcctctttgatgttgctgaaggttcaacactggaagaagcttcaaataactgt
atccgcttagaatggaacaaaggcattgtgggacatgtggcagcacttggtgagcccttg
aacatcaaagatgcatatgaggatcctcggttcaatgcagaagttgaccaaattacaggc
tacaagacacaaagcattctttgtatgccaattaagaatcatagggaagaggttgttggt
gtagcccaggccatcaacaagaaatcaggaaatggtgggacatttactgaaaaagatgaa
aaggattttgctgcttatttggcattttgtggtattgttcttcataatgctcagctctat
gagacttcactgctggagaacaagagaaatcaggtgctgcttgaccttgctagtttaatt
tttgaagaacaacaatcattagaagtaattctgaagaaaatagctgccactattatctct
ttcatgcaagtgcagaaatgcacaattttcatagtggatgaagattgctccgattctttt
tctagtgtgtttcacatggagtgtgaggaattagaaaaatcatctgatacaataacaagg
gaacatgatgcaaacaaaatcaattacatgtatgctcagtatgtcaaaaatactatggaa
ccacttaatatcccagatgtcagtaaggataaaagatttccctggacaactgaaaataca
ggaaatgtaaaccagcagtgcattagaagtttgctttgtacacctataaaaaatggaaag
aagaataaagttataggggtttgccaacttgttaataagatggaggagaatactggcaag
gttaagcctttcaaccgaaatgacgaacagtttctggaagcttttgtcatcttttgtggc
ttggggatccagaacacgcagatgtatgaagcagtggagagagccatggccaaacaaatg
gtcacattggaggttctgtcgtatcatgcttcagcagcagaggaagaaacaagagagcta
cagtcgttagcggctgctgtggtgccatctgcccagacccttaaaattactgactttagc
ttcagtgactttgagctgtctgatctggaaacagcactatgtacaattcggatgtttact
gacctcaaccttgtgcagaacttccagatgaaacatgaggttctttgcagatggatttta
agtgttaagaagaattatcggaagaatgttgcctatcataattggagacatgcctttaat
acagctcagtgcatgtttgctgctctaaaagcaggcaaaattcagaacaagctgactgac
ctggagatacttgcattgctgattgctgcactaagccacgatttggatcaccgtggtgtg
aataactcttacatacagcgaagtgaacatccacttgcccagctttactgccattcaatc
atggaacaccatcattttgaccagtgcctgatgattcttaatagtccaggcaatcagatt
ctcagtggcctctccattgaagaatacaagaccacattgaaaataatcaagcaagctatt
ttagctacagacctagcactgtacattaagaggcgaggagaattttttgaacttataaga
aaaaatcaattcaatttggaagatcctcatcaaaaggagttgtttttggcaatgctgatg
acagcttgtgatctttctgcaattacaaaaccctggcctattcaacaacggatagcagaa
cttgtagcaactgaattttttgatcaaggagacagagagagaaaagaactcaacatagaa
cccactgatctaatgaacagggagaagaaaaacaaaatcccaagtatgcaagttggattc
atagatgccatctgcttgcaactgtatgaggccctgacccacgtgtcagaggactgtttc
cctttgctagatggctgcagaaagaacaggcagaaatggcaggcccttgcagaacagcaa
gagaagatgctgattaatggggaaagcggccaggccaagcggaactga
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