Pongo pygmaeus (Bornean orangutan): 129035600
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Entry
129035600 CDS
T10128
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg00010
Glycolysis / Gluconeogenesis
ppyg00020
Citrate cycle (TCA cycle)
ppyg00620
Pyruvate metabolism
ppyg00785
Lipoic acid metabolism
ppyg01100
Metabolic pathways
ppyg01200
Carbon metabolism
ppyg01210
2-Oxocarboxylic acid metabolism
ppyg04066
HIF-1 signaling pathway
ppyg04922
Glucagon signaling pathway
ppyg05230
Central carbon metabolism in cancer
ppyg05415
Diabetic cardiomyopathy
Module
ppyg_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
129035600 (PDHA2)
00020 Citrate cycle (TCA cycle)
129035600 (PDHA2)
00620 Pyruvate metabolism
129035600 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
129035600 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
129035600 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
129035600 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
129035600 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
129035600 (PDHA2)
Enzymes [BR:
ppyg01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
129035600 (PDHA2)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
129035600
NCBI-ProteinID:
XP_054342107
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All DBs
Position
3:108336984..108338365
Genome browser
AA seq
391 aa
AA seq
DB search
MKNMLAAFISRVLRRVAQKSARRVLVASRNSSNDATFEIKKCDLYLLEECPPVTTVLTRA
EGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVITSYR
AHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIAL
ACKYKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGTSTERAAAI
PDYYKRGNFIPGLKVDGMDVLCVRDATKFAADYCRSGKGPILMELQTYRYHGHSMSDPGV
SYRTREEIQEVRSKRDPIMILQDRMVNSKLATVEELKEIGAEVRKEIDDAAQFATTDPEP
HLEELGHHIYSSDSSFEVRGANPWIKFKSVS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaatatgctggccgccttcatctcccgcgtgttgaggcgagttgcccagaaatca
gctcgcagagtgctggtggcatcccgtaactcctcaaatgacgctacatttgaaattaag
aaatgtgatctttatctgttggaagagtgtccccctgtcactacagtgctcactagggcg
gaggggcttaaatactacaggatgatgctgactgttcgccgcatggaattgaaggcagat
cagctgtacaaacagaaattcatacgcggtttctgtcacctgtgcgatggccaggaagct
tgctgcgtgggccttgaggccggaataaacccctcggatcacgtcattacatcctatagg
gctcatggtgtgtgctatactcggggactttctgtccgatccattctcgcagagctgacg
ggaagaagaggaggttgtgctaaaggaaaaggaggatcgatgcatatgtataccaagaac
ttctatgggggcaatggcatcgtcggtgcgcagggccccctgggcgctggcattgctctg
gcctgtaaatataaaggaaacgatgagatctgtttgactttgtatggggatggcgctgcg
aatcaggggcagatagccgaagctttcaatatggcagctttatggaaattaccttgtgtt
ttcatctgtgagaataacctatatggaatgggaacatctactgagagagcagcagccatc
cctgattactacaagaggggcaattttatccctgggctaaaggtcgatggaatggatgtt
ctgtgcgttcgtgatgcaacaaaatttgcagctgactactgtagatctggaaaggggccc
atactgatggagctgcagacctaccgttatcatggacacagtatgagtgatcctggagtc
agttatcgtacaagagaagaaattcaggaagtaagaagtaagagggatcctataatgatt
ctccaagatagaatggtaaacagcaagctcgccactgtggaagaattaaaggaaattggg
gctgaggtgaggaaagaaattgatgatgctgcccagtttgctaccactgatcctgagcca
catttggaagaattaggccatcacatctacagcagtgattcatcttttgaagttcgtggt
gcaaatccgtggatcaagtttaagtccgtcagttaa
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