Pongo pygmaeus (Bornean orangutan): 129040721
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Entry
129040721 CDS
T10128
Symbol
MET
Name
(RefSeq) hepatocyte growth factor receptor isoform X1
KO
K05099
proto-oncogene tyrosine-protein kinase Met [EC:
2.7.10.1
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg01521
EGFR tyrosine kinase inhibitor resistance
ppyg04010
MAPK signaling pathway
ppyg04014
Ras signaling pathway
ppyg04015
Rap1 signaling pathway
ppyg04020
Calcium signaling pathway
ppyg04151
PI3K-Akt signaling pathway
ppyg04360
Axon guidance
ppyg04510
Focal adhesion
ppyg04520
Adherens junction
ppyg05100
Bacterial invasion of epithelial cells
ppyg05144
Malaria
ppyg05200
Pathways in cancer
ppyg05202
Transcriptional misregulation in cancer
ppyg05205
Proteoglycans in cancer
ppyg05206
MicroRNAs in cancer
ppyg05208
Chemical carcinogenesis - reactive oxygen species
ppyg05211
Renal cell carcinoma
ppyg05218
Melanoma
ppyg05223
Non-small cell lung cancer
ppyg05225
Hepatocellular carcinoma
ppyg05226
Gastric cancer
ppyg05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
129040721 (MET)
04014 Ras signaling pathway
129040721 (MET)
04015 Rap1 signaling pathway
129040721 (MET)
04020 Calcium signaling pathway
129040721 (MET)
04151 PI3K-Akt signaling pathway
129040721 (MET)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
129040721 (MET)
04520 Adherens junction
129040721 (MET)
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
129040721 (MET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129040721 (MET)
05202 Transcriptional misregulation in cancer
129040721 (MET)
05206 MicroRNAs in cancer
129040721 (MET)
05205 Proteoglycans in cancer
129040721 (MET)
05208 Chemical carcinogenesis - reactive oxygen species
129040721 (MET)
05230 Central carbon metabolism in cancer
129040721 (MET)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
129040721 (MET)
05226 Gastric cancer
129040721 (MET)
05218 Melanoma
129040721 (MET)
05211 Renal cell carcinoma
129040721 (MET)
05223 Non-small cell lung cancer
129040721 (MET)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
129040721 (MET)
09174 Infectious disease: parasitic
05144 Malaria
129040721 (MET)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
129040721 (MET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppyg01001
]
129040721 (MET)
Enzymes [BR:
ppyg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
129040721 (MET)
Protein kinases [BR:
ppyg01001
]
Receptor tyrosine kinases (RTK)
MET family
129040721 (MET)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
TIG
Pkinase
Sema
PSI
Kinase-like
Pkinase_fungal
Linker_histone
Motif
Other DBs
NCBI-GeneID:
129040721
NCBI-ProteinID:
XP_054351496
LinkDB
All DBs
Position
6:115373525..115496746
Genome browser
AA seq
1409 aa
AA seq
DB search
MKSKSKSLAECLAQDKPLIMKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKY
QLPNFTAETLIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDC
SSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCI
FSPQIEEPSQCPDCVVSALGAKVLSSIKDRFINFFVGNTINSSYFPDHPLHSISVRRLKE
TKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRF
CSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDI
LFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRT
LLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGR
FMQVVVSRSGPSTPHVNFLLDSHLVSPEVIVEHPLNQNGYTLVVTGKKITKIPLNGLGCR
HFQSCSQCLSAPPFVQCGWCHDKCVRSEECSSGTWTQQICLPAIYKVFPSSAPLEGGTRL
TICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSDSTMNILKCTVGPAMNKHFNMSIIIS
NGHGTTQYSTFSYVDPVITGISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKS
VSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTIT
GVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFF
MLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKS
CENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSI
SIALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESV
DYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPE
LVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEV
SQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDL
IGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKT
GAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRR
LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKC
VAPYPSLLSSEDNADDEVDTRPASFWETS
NT seq
4230 nt
NT seq
+upstream
nt +downstream
nt
atgaagagtaaatccaagagtttagcagaatgcctcgcacaggataaacctctcataatg
aaggcccccgctgtgcttgcacctggcatcctcgtgctcctgtttaccttggtgcagagg
agcaatggggagtgtaaagaggcactagcaaagtccgagatgaatgtgaatatgaagtat
cagcttcccaacttcaccgcggaaacactcatccagaatgtcattctacatgagcatcac
attttccttggtgccactaactacatttatgttttaaatgaggaagaccttcagaaggtt
gctgagtacaagaccgggcctgtgttggaacacccagattgtttcccatgtcaggactgc
agcagcaaagccaatttatcaggaggcgtttggaaagataacatcaacatggctctagtt
gtcgacacctactatgatgatcaactcattagctgtggcagcgtcaacagagggacctgc
cagcgacatgtctttccccacaatcatactgctgacatacagtcggaggttcactgcata
ttctccccacagatagaagagcccagccagtgtcctgactgtgtggtgagcgccctggga
gccaaagtcctttcatctataaaggaccggttcatcaacttctttgtaggtaataccata
aattcttcttatttcccagatcatccattgcattcaatatcagtgagaaggctaaaggaa
acgaaagatggttttatgtttttgacggaccagtcctacattgatgttttacctgagttc
agagattcttaccccattaagtatgtccatgcctttgaaagcaacaattttatttacttc
ttgacggtccaaagggaaactctagatgctcagacttttcacacaagaataatcaggttc
tgttccataaactctggattgcattcctacatggaaatgcctctggagtgtattcttaca
gaaaagagaaaaaagagatccacaaagaaggaagtgtttaatatccttcaggctgcgtat
gtcagcaagcctggggcccaacttgctagacaaataggagccagcctgaatgatgacatt
ctctttggggtgttcgcacaaagcaagccagattctgccgaaccaatggatcgatctgcc
atgtgtgcattccctatcaaatatgtcaacgacttcttcaacaagatcgtcaacaaaaac
aatgtgagatgtctccagcatttttacggacccaatcatgagcactgttttaataggaca
cttctgagaaattcatcaggctgtgaagcgcgccgtgatgaatatcgaacagagtttacc
acagctttgcagcgcgttgacttattcatgggtcaattcagcgaagtcctcttaacatct
atatccaccttcattaaaggagacctcaccatagctaatcttgggacatcagagggtcgc
ttcatgcaggttgtggtttctcgatcaggaccatcaacccctcatgtgaattttctcctg
gactcccatctggtgtctccagaagtgattgtggagcatccattaaaccagaatggctac
acactggttgtcactgggaagaagatcacgaagatcccattgaatggcttgggctgcaga
catttccagtcctgcagtcagtgcctctctgccccaccctttgttcagtgtggctggtgc
catgacaaatgtgtgcgatcggaggaatgctcgagcgggacatggactcaacagatctgt
ctgcctgcaatctacaaggttttcccaagtagtgcaccccttgaaggagggacaaggctg
accatatgtggctgggactttggatttcggaggaataataaatttgatttaaagaaaact
agagttctccttggaaatgagagctgcaccttgactttaagtgacagcacgatgaatata
ttgaaatgcacagttggtcctgccatgaataagcatttcaatatgtccataattatttca
aatggccacgggacaacacaatacagtacattctcctatgtggatcctgtaataacaggt
atttcgccgaaatatggtcctatggctggtggcactttacttactttaactggaaattac
ctaaacagtgggaattccagacacatttcaattggtggaaaaacatgtactttaaaaagt
gtgtcaaacagtattcttgaatgttataccccagcccaaaccatttcaactgagtttgct
gttaaattgaaaattgacttagccaaccgagagacaagcatcttcagttaccgggaagat
cccattgtctacgaaattcatccaaccaaatcttttattagtggtgggagcacaataaca
ggtgttgggaaaaacctgaattcagttagtgtcccgaggatggtcataaatgtgcatgaa
gcaggaaggaactttacagtggcatgtcaacatcgctctaattcagagataatctgctgt
accactccttccctgcaacagctgaatctgcaactccccctgaaaaccaaagcctttttc
atgttagatgggatcctttccaaatactttgatctcatttatgtacataatcctgtgttt
aagccttttgaaaagccagtgatgatctcaatgggcaatgaaaatgtactggaaattaag
ggaaatgatattgaccctgaagcagttaaaggtgaagtgttaaaagttggaaataagagc
tgtgagaatatacacttacattctgaagccgttttatgcacggtccccaatgacctgctg
aaattgaacagcgagctaaatatagagtggaagcaagcaatttcttcaaccgtccttgga
aaagtaatagttcaaccagatcagaatttcacaggattgattgctggtgttgtctcaata
tcaatagcactgttattactacttgggtttttcctgtggctgaaaaagagaaagcaaatt
aaagatctgggcagtgaattagttcgctatgatgcaagagtacacactcctcatttggat
aggcttgtaagtgcccgaagtgtaagcccaactacagaaatggtttcaaatgaatctgta
gactaccgagctacttttccagaagatcagtttcctaattcatctcagaacggttcatgc
cgacaagtgcagtatcctctgacagacatgtcccccatcctaactagtggggactctgat
atatccagtccattactgcaaaatactgtccacattgacctcagtgccctaaatccagag
ctggtccaggcagtgcaacatgtagtgattgggcccagtagcctgattgtgcatttcaat
gaagtcataggaagagggcattttggttgtgtatatcatgggactttgttggacaatgat
ggcaagaaaattcactgtgctgtgaaatccttgaacagaatcactgacataggagaagtt
tcccaatttctgaccgagggaatcatcatgaaagattttagtcatcccaatgtcctctcg
ctcctgggaatctgcctgcgaagtgaagggtctccactggtggtcctaccatacatgaaa
catggagatcttcgaaatttcattcgaaatgagactcataatccaactgtaaaagatctt
attggctttggtcttcaagtagccaaaggcatgaaatatcttgcaagcaaaaagtttgtc
cacagagacttggctgcaagaaactgtatgctggatgaaaaattcacagtcaaggttgct
gattttggtcttgccagagacatgtatgataaagaatactatagtgtacacaacaaaaca
ggtgcaaagctgccagtgaagtggatggctttggaaagtctgcaaactcaaaagtttacc
accaagtcagatgtgtggtcctttggcgtgctcctctgggagctgatgacaagaggagcc
ccaccttatcctgacgtgaacacctttgatataactgtttacttgttgcaagggagaagg
ctcctacaacccgaatactgcccagaccccttatatgaagtaatgctaaaatgctggcac
cctaaagccgaaatgcgcccatccttttctgaactggtgtcccggatatcagcgatcttc
tctactttcattggggagcactatgtccatgtgaacgctacttatgtgaacgtaaaatgt
gtcgctccatatccttctctgttgtcatcagaagataacgctgatgatgaggtggacaca
cgaccagcctccttctgggagacatcatag
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integrated database retrieval system