Pongo pygmaeus (Bornean orangutan): 129042234
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Entry
129042234 CDS
T10128
Symbol
WRN
Name
(RefSeq) bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN
KO
K10900
werner syndrome ATP-dependent helicase [EC:
5.6.2.4
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Brite
Enzymes [BR:
ppyg01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.4 DNA 3'-5' helicase
129042234 (WRN)
DNA replication proteins [BR:
ppyg03032
]
Eukaryotic type
DNA Replication Termination Factors
Other termination factors
129042234 (WRN)
DNA repair and recombination proteins [BR:
ppyg03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
RecQ family DNA helicases
129042234 (WRN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
129042234
NCBI-ProteinID:
XP_054353931
LinkDB
All DBs
Position
7:31169883..31311909
Genome browser
AA seq
1459 aa
AA seq
DB search
MSEKKLETTPQQRKCPEWMNAQNKRCAVEERKACVRKSVFEDDLPFLEFTGSIVYSYDAS
DCSFLSEDISMSLSDGDVVGFDMEWPPLYKKRKLGKVALIQLCVSESKCYLFHISSMSVF
PQGLKMLLENKAVKKAGVGIEGDQWKLLRDFDIKLKNFVELADVANKKLKCTETWSLNSL
VKHLLGKQLLKDKSIRCSNWSKFPLTEDQKLYAATDAYAGFIIYRNLEILDDTVQRFAIN
KEEEILLSNMNKQLTSISEEVMDLAKHLPDAFSKLENPRRVSILLKDISENLYSLRKMII
GSTNIETELRPSNNLNLLSFEDSTTGRVQQKQIREHEVLINVEDETWDPTLDHLAKHDGE
DVLGNKVERKEDGFEDGVEDNKLKENTERACLMSLDITEHELQILEQQAQEEYLSDIAYK
STEHLSPNNNENDTSYVIESDEDLEMEMLKHLSPNNNENDTSYVIESDEDLEMEMLKPLS
PNNNENDTSHVIESDEDLEMEMLKHLSPNNNENDTSHVIESDEDLEMEMLKSLENLNSGT
VEPTHSKCLKMERNLGLPTKEEEDDDENEANEEEKDDDKDSLLPAPNEEQVTCLKMYFGH
SSFKPVQWKVIHSVLEERRDNVAVMATGYGKSLCFQYPPVYVGKIGLVISPLISLMEDQV
LQLKMSNVPACFLGSAQSENVLTDIKLGKYRIVYITPEYCSGNMGLLQQLEADIGITLIA
VDEAHCISEWGHDFRNSFRKLGSLKTALPMVPIVALTATASSSIQEDIVRCLNLRNPQIT
CTGFDRPNLYLEVRRKTGNILQDLQPFLVKTSSHWEFEGPTIIYCPSRKMTEQVTAELRK
LNLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGINKADIRQVIHYGAPKEME
SYYQEIGRAGRDGLQSSCHVLWAPADINLNRHLLTEIRNEKFRLYKLKMMAKMEKYLHSS
RCRRQIILSHFEDKQVQKASLGIMGTEKCCDNCRSRLDNYYSMDDSEDTSWDFGPQAFKL
LSAVDILEEKFGIGLPILFLRGSNSRRLADQYRRHSLFGTGKDQTESWWKAFSRQLITEG
FLVEVPGYNKFVKICTLTRKGRNWLHKANTESQSLILQANEELCPKKFLLPSSKTVSSGT
KEHYYNQVPVELTTEKKSNLEKLYSYKPCDKISSGSNISKKSIMVQSPEKSYSSSEPAIS
SQEQETQIVLYGKLVEARQKHANKMDVPPAILATNKILVDMAKMRPTTVENIKRIDGVSE
GKAAMLAPLLEVIKHFCQTNNVQTDLFSSTKPQEEQKTSLVAKKKICTLSQSMAITYSLF
QEKKMPLKSIAESRILPLMTIGMHLSQAVKAGCPLDLERAGLTPEVQKIIADVIRNPPVN
SDMSKINLIRMLVPENIDTYLIHMAIEILKHGPDSRLQPSCDVNKRRCFPSSEEICSSSK
RSKEEVGINTETSSAERKR
NT seq
4380 nt
NT seq
+upstream
nt +downstream
nt
atgagtgaaaaaaaattggaaacaactccacagcagcggaaatgtcccgaatggatgaat
gcgcagaataaaagatgtgctgtagaagaaagaaaggcatgtgttcggaagagtgttttt
gaagacgacctccccttcttagaattcactggatccattgtgtatagttatgacgctagt
gattgctctttcctgtcggaagatattagcatgagtctatcagatggggatgtggtggga
tttgacatggagtggccaccattatacaagaaacggaaacttggcaaagttgcactaatt
cagttgtgtgtgtctgagagcaaatgttacttgttccacatttcttccatgtcagttttt
ccccagggattaaaaatgttgcttgaaaataaagcagttaaaaaggcaggtgtaggaatt
gaaggagatcagtggaaacttctacgtgactttgatatcaaattgaagaattttgtggag
ttggcagatgttgccaataaaaagctgaaatgtacagagacctggagcctcaacagtctg
gttaaacacctcttaggtaaacagctcctgaaagacaagtctatccgctgtagcaattgg
agtaaatttcctctcactgaggaccagaaactgtatgcagccactgatgcttatgctggt
tttattatttaccgaaatttagaaattttggatgatactgtgcaaaggtttgctataaat
aaagaggaagaaatcctacttagcaacatgaacaaacagttgacttcaatctctgaggaa
gtgatggatctggctaagcatcttcctgatgctttcagtaaattggaaaacccacggagg
gtttctatcttactgaaggatatttcagaaaatctatattcactgaggaagatgataatt
gggtctactaacattgagactgaactgaggcccagcaataatttaaacttattatccttt
gaagattcaactactgggcgagtacaacagaaacaaattagagaacatgaagttttaatt
aacgttgaagatgaaacatgggatccaacacttgatcatttagctaaacatgatggagaa
gatgtacttggaaataaagtggaacgaaaagaagatggatttgaagatggggtagaagac
aataaattgaaagagaatacggaaagagcttgtttgatgtcgttagatattacagaacat
gaactccaaattttggaacagcaggctcaggaagaatatcttagtgatattgcttataaa
tctactgagcatttatctcccaataataatgaaaacgatacgtcctatgtaattgagagc
gatgaagatttagaaatggaaatgcttaagcatttatctcccaataataatgaaaacgat
acgtcctatgtaattgagagcgatgaagatttagaaatggaaatgcttaagcctttatct
cccaataataatgaaaacgatacgtcccatgtaattgagagcgatgaagatttagaaatg
gagatgcttaagcatttatctcccaataataatgaaaacgatacgtcccatgtaattgag
agcgatgaagatttagaaatggagatgcttaagtctttagaaaacctcaatagtggcacg
gtagaaccaactcattctaaatgcttaaaaatggaaagaaatctgggtcttcctactaaa
gaagaagaagatgatgatgaaaatgaagctaatgaagaggaaaaagatgatgataaggac
tctttgttgccagcacccaatgaagagcaagttacttgcctgaagatgtactttggccat
tccagttttaaaccagttcagtggaaagtgattcattcagtattagaagaaagaagagat
aatgttgctgtcatggcaactggatatggaaagagtttgtgcttccagtatccacctgtt
tatgtaggcaagattggccttgtcatctctccccttatttctctgatggaagaccaagtg
ctacagcttaaaatgtccaacgtcccagcttgcttccttggatcagcacagtcagaaaat
gttctaacagatattaaattaggtaaataccggattgtatatataactccagaatactgt
tcaggtaacatgggcctgctccagcaacttgaggctgatattggtatcacactcattgct
gtggatgaggctcactgtatttctgagtgggggcatgattttaggaattcattcaggaag
ttgggctccctaaagacagcactgccaatggttccaattgttgcacttactgctactgca
agttcttcaatccaggaagacattgtacgttgcttaaatttaagaaatcctcagatcacc
tgtactggttttgatcgaccaaacctgtatttagaagttaggcgaaaaacagggaatatc
cttcaggatctgcagccatttcttgtcaaaacaagttcccactgggaatttgaaggtcca
acaatcatctactgtccttctagaaaaatgacagaacaagttacagctgaacttaggaaa
ctgaatctatcctgtggaacataccatgcgggcatgagttttagcacaaggaaagacatt
catcataggtttgtgagagatgaaattcagtgtgttatagctaccatagcttttggaatg
ggcattaataaagctgacattcgccaagtcattcattacggtgctcctaaggaaatggaa
tcatattatcaggagattggtagagctggtcgtgatggacttcaaagttcttgtcacgtc
ctctgggctcctgcagacattaacttaaataggcatcttcttactgagatacgtaatgag
aagtttcgattatacaaattaaagatgatggcaaagatggaaaagtatcttcattctagc
agatgtaggagacaaatcatcttgtctcattttgaggacaaacaagtacaaaaagcctcc
ttgggaattatgggaactgaaaaatgctgtgataattgcaggtccagattggataattac
tattccatggatgactcagaggatacatcctgggactttggtccacaagcatttaagctt
ttgtctgctgtggacatcttagaggaaaaatttggaattgggcttccaattttatttctc
cgaggatctaattctcggcgtcttgccgatcaatatcgcaggcacagtttatttggcact
ggcaaggatcaaacagagagttggtggaaggctttttcccgtcagctcatcactgaggga
ttcttggtagaagttcctgggtataacaaatttgtgaagatttgcacccttacgagaaag
ggtagaaattggcttcataaagcaaatacagaatctcagagcctcatccttcaagctaat
gaagaattgtgtccaaagaagtttcttctgcctagctcgaaaactgtatcttcaggcacc
aaagagcattattataatcaagtaccagttgaattaactacagagaagaagtctaacttg
gagaagttatattcttataaaccatgtgataagatttcttctgggagtaacatttctaaa
aaaagtatcatggtacagtcaccagaaaaatcttacagttcctcagagcctgctatttcg
tcacaagagcaggaaactcagattgtgttatatggcaaattggtagaagctaggcagaaa
catgccaataaaatggatgttcccccagctattctggcaacaaacaagatactggtggat
atggccaaaatgagaccaactacagttgaaaacataaaaaggattgatggtgtttctgaa
ggcaaagctgccatgttggcccctctgttggaagtcatcaaacatttctgccaaacaaat
aatgttcagacagacctcttttcaagtacaaaacctcaagaagaacagaagacgagtctg
gtagcaaaaaaaaaaatatgcacactttcacagtctatggccatcacatactctttattc
caagaaaagaagatgcctttgaagagcatagctgagagcaggattctgcctctcatgaca
attggcatgcacttatcccaagcagtgaaagctggctgcccccttgatttggagcgagca
ggcctgactccagaggttcagaagattattgctgatgttatccgaaaccctcccgtcaac
tcagatatgagtaaaattaacctaatcagaatgttagttcctgaaaacattgacacgtac
cttatccacatggcaattgagatccttaaacatggtcctgacagcagacttcaaccttca
tgtgatgtcaacaaaaggagatgttttcccagttctgaagagatctgttcaagttctaag
agaagcaaggaagaagtaggcatcaataccgagacttcatctgcagagagaaagagatga
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