Pongo pygmaeus (Bornean orangutan): 129043726
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Entry
129043726 CDS
T10128
Symbol
HMGCL
Name
(RefSeq) hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X1
KO
K01640
hydroxymethylglutaryl-CoA lyase [EC:
4.1.3.4
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg00280
Valine, leucine and isoleucine degradation
ppyg00650
Butanoate metabolism
ppyg01100
Metabolic pathways
ppyg04146
Peroxisome
Module
ppyg_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
129043726 (HMGCL)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
129043726 (HMGCL)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
129043726 (HMGCL)
Enzymes [BR:
ppyg01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.3 Oxo-acid-lyases
4.1.3.4 hydroxymethylglutaryl-CoA lyase
129043726 (HMGCL)
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Motif
Pfam:
HMGL-like
Motif
Other DBs
NCBI-GeneID:
129043726
NCBI-ProteinID:
XP_054356610
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Position
1:206953621..206977700
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AA seq
325 aa
AA seq
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MAAMRKALPRRLVGLASLRAVSTSSMGTLPKRVKIVEVGPRDGLQNEKNIVSTPVKIKLI
DMLSEAGLSVIETTSFVSPKWVPQMGDHTEVLKGIQKFPGINYPVLTPNLKGFEAAVAAG
AKEVAIFGAASELFTKKNINCSIEESFQRFDAILKAAQSANISVRGYVSCALGCPYEGKI
SPAKVAEVTKKLYSMGCYEISLGDTIGVGTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQ
ALANTLMALQMGVSVVDSSVAGLGGCPYAQGASGNLATEDLVYMLEGLGIHTGVNLQKLL
EAGNFICQALNRKTSSKVAQATCKL
NT seq
978 nt
NT seq
+upstream
nt +downstream
nt
atggcagcgatgaggaaggcgcttccgcggcgactggtgggcttggcgtccctccgggct
gtcagcacctcatctatgggcactttaccaaagcgggtgaaaattgtggaagttggtccc
cgagatggactacaaaatgaaaagaatatcgtatctactccagtgaaaatcaagctgata
gacatgctttctgaagcaggactctctgttatagaaaccaccagctttgtgtctcctaag
tgggttccccagatgggtgaccacactgaagtcttgaagggcattcagaagtttcctggc
atcaactacccagtcctgaccccaaatttgaaaggcttcgaggcagcggttgctgctgga
gccaaggaagtagccatctttggagctgcctcagagctcttcaccaagaagaacatcaat
tgttccatagaggagagttttcagaggtttgacgcaatcctgaaggcagcgcagtcagcc
aatatttctgtgcgggggtacgtctcctgtgctcttggctgcccttatgaagggaagatc
tccccagctaaagtagctgaggtcaccaagaagttgtattcaatgggctgctacgagatc
tccctgggggacaccattggtgtgggcaccccagggatcatgaaagacatgctgtctgct
gtcatgcaggaagtgcctctggctgccctggctgtccactgccatgacacctatggccaa
gccctggccaacaccttgatggccctgcagatgggagtgagtgtcgtggactcttctgtg
gcaggacttggaggctgtccctacgcacagggggcatcaggaaacttggccacggaagac
ctagtctacatgctagagggcttgggcattcacacgggtgtgaatctccagaagcttctg
gaagctggaaactttatctgtcaagccctgaacagaaaaactagctccaaagtggctcag
gctacctgtaaactctga
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