Pongo pygmaeus (Bornean orangutan): 129044357 Help Entry 129044357         CDS       T10128                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4   KO K10160   toll-like receptor 4 Organism ppyg  Pongo pygmaeus (Bornean orangutan) Pathway ppyg04064   NF-kappa B signaling pathway ppyg04066   HIF-1 signaling pathway ppyg04145   Phagosome ppyg04151   PI3K-Akt signaling pathway ppyg04217   Necroptosis ppyg04613   Neutrophil extracellular trap formation ppyg04620   Toll-like receptor signaling pathway ppyg04621   NOD-like receptor signaling pathway ppyg04936   Alcoholic liver disease ppyg05132   Salmonella infection ppyg05133   Pertussis ppyg05134   Legionellosis ppyg05135   Yersinia infection ppyg05140   Leishmaniasis ppyg05142   Chagas disease ppyg05144   Malaria ppyg05145   Toxoplasmosis ppyg05146   Amoebiasis ppyg05152   Tuberculosis ppyg05161   Hepatitis B ppyg05162   Measles ppyg05164   Influenza A ppyg05170   Human immunodeficiency virus 1 infection ppyg05171   Coronavirus disease - COVID-19 ppyg05205   Proteoglycans in cancer ppyg05235   PD-L1 expression and PD-1 checkpoint pathway in cancer ppyg05321   Inflammatory bowel disease ppyg05323   Rheumatoid arthritis ppyg05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ppyg00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     129044357 (TLR4)    04066 HIF-1 signaling pathway     129044357 (TLR4)    04151 PI3K-Akt signaling pathway     129044357 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     129044357 (TLR4)   09143 Cell growth and death    04217 Necroptosis     129044357 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     129044357 (TLR4)    04620 Toll-like receptor signaling pathway     129044357 (TLR4)    04621 NOD-like receptor signaling pathway     129044357 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     129044357 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     129044357 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     129044357 (TLR4)    05161 Hepatitis B     129044357 (TLR4)    05171 Coronavirus disease - COVID-19     129044357 (TLR4)    05164 Influenza A     129044357 (TLR4)    05162 Measles     129044357 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     129044357 (TLR4)    05135 Yersinia infection     129044357 (TLR4)    05133 Pertussis     129044357 (TLR4)    05134 Legionellosis     129044357 (TLR4)    05152 Tuberculosis     129044357 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     129044357 (TLR4)    05144 Malaria     129044357 (TLR4)    05145 Toxoplasmosis     129044357 (TLR4)    05140 Leishmaniasis     129044357 (TLR4)    05142 Chagas disease     129044357 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     129044357 (TLR4)    05321 Inflammatory bowel disease     129044357 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     129044357 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     129044357 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ppyg04131]     129044357 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:ppyg04054]     129044357 (TLR4)    04090 CD molecules [BR:ppyg04090]     129044357 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:ppyg00536]     129044357 (TLR4) Membrane trafficking [BR:ppyg04131]  Endocytosis   Phagocytosis    Toll-like receptors     129044357 (TLR4) Pattern recognition receptors [BR:ppyg04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    129044357 (TLR4) CD molecules [BR:ppyg04090]  Proteins   129044357 (TLR4) Glycosaminoglycan binding proteins [BR:ppyg00536]  Hyaluronan   Cell surface receptors    129044357 (TLR4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  LRR_8 TIR LRR_4 LRR_1 TIR_2 LRR_9 LRR_Zer-1 LRR_6 LRR_EndoS ThsB_TIR LRR_R13L1-DRL21 Curto_V2 Motif Other DBs NCBI-GeneID:  129044357 NCBI-ProteinID:  XP_054358230 LinkDB All DBs Position 13:108288033..108301328 Genome browser AA seq 830 aa AA seqDB search MMSASRLAGTLIPAMAFLSCVRPESWEPCVEVVPNITYQCMELNFYKIPDNLPFSTKNLD LSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGNPIQNLALG AFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEHL DLSSNKIQSIYCKDLQVLHQMPLLNLSLDLSLNAMNFIQPGAFKEIRLHKLTLRNSFDSL NVMKTCIQGLAGLEVHHLVLGEFRNEKNLEKFDTSALEGLCNLTIEEFRLAYLDYYLDDI IDLFNCLANVSSFSLVSVTIKSVKDFSYNFGWQHLELVNCKFGQFPTLELKSLKRLTFTA NKGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTTSLKYLDLSFNDVITMGSNFLG LEQLEHLDFQHSNLKQMSEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLSSLKVLKMAG NSFQENFLPDIFTELRNLTFLDLSQCQLEQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPY KCLNSLQVLDYSLNHIMTSKKQELQHFPSSLAFLNLTQNDFACTCEHQSFLQWIKDQKQL LVEVERMECATPSDKQGMPVLSLNITCQMNKTIIGVSVFSVLVVSVVAVLVYKFYFHLML LAGCIKYGRGENTYDAFVIYSSQDEDWVRNELVKNLEEGVPTFQLCLHYRDFIPGVAIAA NIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLR QQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKSWNPEGTVGTG NT seq 2493 nt NT seq  +upstreamnt  +downstreamnt atgatgtctgcctcgcgcctggctgggactctgatcccagccatggccttcctctcctgc gtgagaccggaaagctgggagccctgcgtagaggtggttcctaacattacttatcaatgc atggagctgaatttctacaaaatccccgacaacctccccttctcaaccaagaacctggac ctgagctttaatcccctgaggcatttaggcagctatagcttcttcagtttcccagaactg caggtgctggatttatccaggtgtgaaatccagacaattgaagatggggcatatcagagc ctaagccacctctccaccttaatattgacaggaaaccccatccagaatttagccctggga gccttttctggactgtcaagtttacagaagctggtggctgtggagacaaatctggcatct ctagagaacttccccattggacatctcaaaactttgaaagaacttaatgtggctcacaat cttatccagtctttcaaattacctgagtatttttccaatctgaccaatctagagcacttg gacctttccagcaacaagattcaaagtatttattgcaaagacttgcaggttctacatcaa atgccgctactcaatctctctttagacctgtccctgaacgctatgaactttatccaacca ggtgcatttaaagaaattaggcttcataagctgactttgagaaatagttttgatagttta aatgtaatgaaaacttgtattcaaggtctggctggtttagaagtccatcatttggttctg ggagaatttagaaatgaaaaaaacttggaaaagtttgacacatctgctctagagggcctg tgcaatttgaccattgaagaattccgattagcatacttagactactacctcgatgatatt attgacttatttaattgtttggcaaatgtttcttcattttccctggtgagtgtgactatt aaaagtgtaaaagacttttcttataatttcggatggcaacatttagaattagttaactgt aaatttggacagtttcccacattggaactcaaatctctcaaaaggcttactttcactgcc aacaaaggtgggaatgctttttcagaagttgatctaccaagccttgagtttctagatctc agtagaaatggcttgagtttcaaaggttgctgttctcaaagtgattttgggacaaccagc ctaaagtatttagatctgagcttcaatgatgttattaccatgggttcaaacttcttgggc ttagaacaactagaacatctggatttccagcattccaatttgaaacaaatgagtgagttt tcagtattcctatcactcagaaacctcatttaccttgacatttctcatactcacaccaga gttgctttcaatggcatcttcaatggcttgtccagtctcaaagtcttgaaaatggctggc aattctttccaggaaaacttccttccagatatcttcacagagctgagaaacttgaccttc ctggacctctctcagtgtcaactggagcagttgtctccaacagcatttaactcactctct agtcttcaggtactaaatatgagccacaacaacttcttttcattggatacgtttccttat aagtgtctgaactccctccaggttcttgattacagtctcaatcacataatgacttccaaa aaacaggaactacagcattttccaagtagtctagctttcttaaatcttactcagaatgac tttgcttgtacttgtgaacaccagagtttcctgcagtggatcaaggaccagaagcagctc ttggtggaagttgaacgaatggaatgtgcaacaccttcagataagcagggcatgcctgtg ctgagtttgaatatcacctgtcagatgaataagaccatcattggtgtgtcagtcttcagt gtgcttgtagtatctgttgtagcagttctggtctataagttctattttcacctgatgctt cttgctggctgtataaagtatggtagaggtgaaaacacgtatgatgcctttgttatctac tcaagccaggatgaggactgggtaaggaatgagctagtaaagaatttagaagaaggggta cctacctttcagctctgccttcactacagagactttattcccggtgtggccattgctgcc aacatcatccatgaaggtttccataaaagccgaaaggtgattgttgtggtgtcccagcac ttcatccagagccgctggtgtatctttgaatatgagattgctcagacctggcagtttctg agcagtcgtgctggtatcatcttcattgtcctgcagaaggtggagaagaccctgctcagg cagcaggtggaactgtaccgccttctcagcaggaacacttacctggagtgggaggacagt gtcctggggcggcacatcttctggagacgactcagaaaagccctgctggatggtaaatca tggaatccagaaggaacagtgggtacaggataa

DBGET integrated database retrieval system