Pongo pygmaeus (Bornean orangutan): 129044372
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Entry
129044372 CDS
T10128
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X2
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg05014
Amyotrophic lateral sclerosis
Brite
Enzymes [BR:
ppyg01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
129044372 (SETX)
5.6.2.5 RNA 5'-3' helicase
129044372 (SETX)
Transcription machinery [BR:
ppyg03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
129044372 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
129044372
NCBI-ProteinID:
XP_054358253
LinkDB
All DBs
Position
13:complement(122965587..123061893)
Genome browser
AA seq
2720 aa
AA seq
DB search
MSTCCWCTPGGASTVDFLKRYASNTPSSEFQTADEDLCYCLECVAEYHKARDELPFLHEV
LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLICLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN
PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVVHHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFTRSSEKSSGSCSKGTAMISSLSLHSMPSNSVQLACVQLIR
SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQTCLKQIIRNIKFKAP
PCNTFVDLTSTCKTSPASYSKEESEQIGKMSRKDMHCLEASSPTFSKEPMKVQDSVLIKA
DNTIEGDNNEQNYIKDVKLEDHLSAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS
YTPKDCTSRNDPERGCDRGIIVSTRLLTDSSTDALEKVSASNEDFSLKDDALAKTSKRKT
KVKKDEICAKLSHVIKKQHRKSTLVDDTINLDENLTVSNIESFYSRKDTGVQKGDGFTHD
LSLDPGGVLDDDKNGEQKSQNNVLPKEKQLKNEELDIFSSHENNCKIQEFHDDKDLISFT
EMTNTSEKKSCPFKDLMTVPESRDEEMSNSTNVIYSNLTREQALGISPKSDTLTDSQIDR
DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTAHQNNVGDTSRGQVIIISDSD
DDDDDERILSLEKLTKQDKICLEKERPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQ
YFEFESSSEVFSVWQDHLDDNNSVQDGEKKCLAPIANATNGQGCTDYVSEVVKKGAEGIE
EHTRPQSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRELVGNDFK
SMDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPVKKVPVSKTPKKTHSDAKKGQSRSSNY
LSCRTTPAIVPPKKFRQCPEPASTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGV
VDTRKKTKLISPQNLSVRNKKKLLTSQELQMQRQIRPKSQKNRQRLSDSESTDVTRAGSH
TAHNSDVFLPESDRSDYNCTGGTEALANSNRKQLIKCMPSEPETIKAKHGSPATDDACPL
NQCDSVVLNGTIPTNEVIVCTSEDPLGGGDPTAHHIEMATLKEGEPDSSSDAEEENLFLT
QNDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTK
NQGEYCPKHSEVKAADEDVFRKPGLPPSASKPLRPTTKIFSSKSTSRIAGLSKSLETSSA
LSPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGES
KYFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHN
YGDYFNIFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECEL
AKQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKAECYL
SIQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDL
LTTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYR
LLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCG
DINLVRLGPEKSINNEVLKFSLDSQVDHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRA
LCRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHVICCTLSTSG
GLLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMK
AQEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKT
NRQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSF
RNIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSVQGSI
GNSSVPGTLYWDGEFLASLQRLNVTITRAKYSLFILGHLRTLMQLLPRSFCVHVNHSPFF
SPEPKYLHWALKENQHWNQLIQDAQKRGAIIKTCDKNYRHDAVKILKLKPVLQRSLTHPP
TIAPEVSRPQGGLPSSKLDSGFAKTSVAASLYHTPSDSKETTLTVTSKDPERPPVHDQLR
DPRLLKRMGIEVKGGIFLWDPQPSSPQHPGATPPTGESGFPVVHQDLSHVQQPAAVVAAL
SSHKPPVQGEPPAASPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSETHHTRRNS
RWDKRRLEQEDNSSKKRKLL
NT seq
8163 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtacgccaggtggtgcttccaccgttgacttcctaaagcgc
tatgcttccaacacaccgtccagtgaatttcaaacagctgatgaagacctctgctactgc
ttggagtgtgtggctgagtaccacaaagcaagagatgaattgccattcttgcatgaggtt
ttatgggaattagaaaccttacgtctcataaatcactttgaaaaatccatgaaggcagaa
attggagatgatgatgagttatatatagtagacaacaatggagagatgccactgtttgac
atcactgggcaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaatat
ccttacttgcttctacatgaacgtgttaacgagttatgtgttgaagcactttgtcggatg
gaacaagccaattgctcctttcaggtgtttgacaaacatccagggatctatttgttttta
gtccatcccaatgaaatggttcggcgttgggctatcttgactgcaagaaacttggggaag
gtggacagagatgattattatgacttacaagaagttttaatttgcctttttaaagtcatt
gagttggggcttttagagagtccagacatttatacttcttctgtcctagagaagggtaaa
ctgattcttctgccctcacacatgtatgatactaccaactacaaaagctattggttaggt
atttgcatgttgctgaccattcttgaagaacaagccatggattccctattgttgggctca
gacaaacaaaatgattttatgcaatcgatacttcacactatggagagggaagcagatgat
gatagtgtggatcctttctggccagcgttacactgttttatggtgattctggatcgtctt
ggatctaaggtctggggtcaacttattgatcctattgaggcgtttcaaaccattatcaac
aacgcaagctacaatagagagatccgacatatacggaacagctctgtaaggaccaagtta
gaaccggagtcctatttggatgatatggtgacttgtagccagatcgtatacaattataat
cctgaaaagaccaaaaaggattctggatggagaacagccatttgcccagattattgtcct
aacatgtatgaagaaatggaaacattagccagtgtacttcagtcagatattggtcaagac
atgcgtgttcataatagcacatttctatggttcatcccttttgtccagtccctcatggat
cttaaggatttgggtgtggcttacatagtagaggttgttcatcatctgtactctgaagtc
aaagaagtcctcaaccaaacagatgccgtgtgtgacaaagtcactgaattttttcttcta
attttggtatcagtgattgaactgcatagaaataaaaaatgtttgcatttgctgtgggta
agttcccagcaatgggtggaagccgtcgtcaaatgtgccaagcttcctaccactgcgttt
acacgaagttctgagaaatcatctggaagttgctccaaaggaacagcaatgatatcgtca
ctgtcgttgcattccatgccatctaactctgtacaactggcttgtgtgcagctgatcaga
agtctccttaaagaaggttatcagcttgggcagcagtctctttgcaagcgattctgggat
aagctcaacttattccttagaggaaatttatctctaggttggcagttgactagtcaggaa
acccatgagctgcaaacttgtttaaagcaaattattagaaacataaaattcaaagcacct
ccatgtaacacttttgtggatctgacttctacatgtaaaacctctcctgcatcttatagt
aaagaagaaagtgaacaaatagggaagatgtctagaaaagatatgcattgtttggaagct
tccagcccaacattttctaaagaaccaatgaaagtgcaagacagtgtattgatcaaagca
gataacactatagaaggtgacaataatgagcaaaattatataaaggatgtgaaactagaa
gaccatctctcagctgggtcatgcttaaagcagagtagtaaaaacatttttactgaaaga
gctgaagatcaaattaaaataagtacaaggaagcagaagtctgtaaaagagatctcttca
tatacaccaaaggattgtacttcaagaaatgatccagaaaggggatgtgacagaggaata
atagtatcaacacgtttgttgactgattctagcactgatgctttggaaaaagtgtccgca
tcaaatgaagatttctctttaaaggatgatgctcttgctaaaacctcaaaacgaaaaact
aaggtaaagaaagatgaaatctgtgcaaagttatcacatgtaataaagaagcaacacagg
aagagtactttggtcgatgatactatcaacttagatgaaaatttgactgtatctaacatt
gagagtttctattcaaggaaagatacaggagttcagaaaggagatggtttcacacacgat
ctttctttagaccctggtggtgttctggatgatgataagaatggagaacaaaaatctcaa
aacaatgtattgccaaaagagaaacaattaaagaatgaagaattagatattttctcttcc
catgaaaacaattgtaaaatacaggaatttcatgatgataaagatttgatctcctttaca
gaaatgaccaatacttcagagaagaaatcatgtccctttaaagatcttatgactgtacct
gaatcaagagatgaggagatgagtaacagtaccaatgtgatttattctaacttgacaaga
gaacaagcccttggcatcagtcctaaatccgacaccttaacggattctcagatagacaga
gaccttcacaaattatctttactagctcaagccagtgttattacgttcccatccgattca
cctcagaactcatcgcagctgcaaaggaaagtaaaagaggataaaagatgtttcacagct
caccaaaataatgttggagatacctcccgtggacaggttattattatttcagattctgat
gatgatgatgatgatgaaagaatcctgagtcttgagaaactcactaaacaggacaaaata
tgccttgagaaggaacgtccagagcagcacgtttcaacagttaatagtaaggaggaaaag
aatccagtaaaggaagaaaagacagagactctctttcagtttgaggaatctgattctcag
tattttgagtttgaaagttcatctgaagtgttttcagtttggcaagatcatctagacgat
aataattcagttcaagatggtgagaaaaaatgtttggctcctatagccaatgccacaaat
ggtcagggttgtacagattatgtatctgaagttgttaaaaaaggagcagagggcattgaa
gaacacacaagaccacagagtatttctgttgaggaattttgtgaaattgaagtaaaaaag
cctaagagaaaacgatctgaaaaaccaatggctgaagatcctgtgaggccttcatcttct
gtcagaaatgagggccagtctgatactaataagagagagcttgttggaaatgattttaaa
agtatggatagaaggacttcaactcccaattcacgtattcagagagccactacggtttca
cagaagaagtcttcgaagctttgtacttgtacagaacccgtcaagaaagttccagtttct
aagacccctaagaaaactcattcagatgccaaaaaaggacagagtagaagttcaaattac
ctaagttgtagaacaactcctgctatagtgccaccaaagaaatttcgtcagtgtcctgag
ccagcttcaacagctgagaaacttggcctgaagaagggtcctcgtaaggcgtatgagctg
tcccagcggtctttggattatgtagctcagttacgggatcatggcaaaactgttggagta
gttgatacccgaaaaaagactaaattaatttctcctcagaacctgtctgtcagaaataag
aagaaacttctgactagtcaagaacttcagatgcaaaggcagatcagacccaaatcacaa
aaaaatagacaaagactttctgatagtgaaagtacagatgttacaagagcagggtcacat
acagcacataattctgacgtatttctcccagaatctgataggtcagattataattgtaca
ggaggaactgaggcactcgccaacagtaacagaaaacagttaataaaatgcatgccttct
gaaccagaaaccataaaagcaaaacatgggtctccagcaactgatgatgcttgccctttg
aaccagtgtgattctgtagtgttaaatggaacaataccaacaaatgaagtaattgtctgt
acttcagaggaccctctgggtggaggtgatccaacagcacatcatatagagatggcaact
ttgaaagagggagaacctgactccagcagtgatgcagaggaggagaacttatttttaaca
caaaatgatcctgaagatatggatttatgttcacaaatggagaatgacaattataaactc
attgaactaattcatggaaaagatacagttgaggttgaagaagattctgtaagtcggcct
cagttggaatctttgagtggcacaaagtgtaagtacaaagattgtcttgaaaccacaaaa
aaccagggtgaatactgcccaaaacactctgaagtgaaagcagcagatgaagatgtattt
cgtaaacctggcttgcctccttctgcatctaaacctttgagacctaccactaagattttt
agctcaaagagtacttcacgaattgctggtctttctaaatctttggaaacttcttcagca
ctttcaccatctctaaagaataagtcaaaggggatacagtcgattttgaaagtgccacag
ccagttcccctcatagctcagaagccagttggtgaaatgaagaattcgtgcaatgttctt
catcctcagtctccgaataattccaacaggcaaggttgcaaagttccatttggtgaaagc
aaatattttccatcttcctctccagtaaacattctcttgtcatcacagtctgtctctgac
accttcgttaaagaggtcttaaaatggaaatatgaaatgtttttgaactttggtcagtgt
gggccccctgcaagtctttgtcagtccatctcaagacctgtgcctgtcagatttcacaat
tatggagattattttaatatttttttccctttgatggtattgaatacttttgaaacagtg
gcacaggaatggctcaactctccaaatagagagaatttctatcagttgcaagtacgaaaa
tttcctgccgattatataaaatactgggagtttgcagtttatctggaagaatgtgaactg
gctaaacagctttatccaaaggaaaacgatttggtgtttttagctcctgagagaataaat
gaagagaagaaagatacagagagaaatgacatacaagatctccacgaatatcattctggt
tatgttcataaatttcgccgcacttcagtcatgcgtaatgggaaagctgagtgttacctt
tccatccagactcaagagaactttccggccaatttaaacgaacttgtcaattgtattgta
atcagttctctggtaactacacaaaggaagttgaaagccatgtctctgttgggtagtcgg
aaccaactggctagagctgttctgaatccaaaccctatggacttctgtacaaaagattta
ctgactacaacatctgagagaattattgcgtacttaagagatttcaatgaagaccaaaag
aaagcaatagaaactgcatatgctatggtgaaacactcaccatcagttgccaaaatctgc
ttgattcatggaccacctggaacaggaaaatcaaaaactattgttggcctcctctatcgt
ctactgacagagaaccagaggaaggggcattcagacgaaaactccaatgccaaaatcaaa
caaaaccgtgtccttgtgtgtgcaccttccaatgcagctgttgatgaactcatgaaaaaa
attatccttgaattcaaagaaaaatgtaaagacaagaagaatcctttaggaaactgtgga
gatataaatttagtacgactgggtccagaaaagtctattaataatgaggttctaaagttc
agtttggacagccaagtagaccacagaatgaaaaaagagttaccttctcatgttcaggcg
atgcataaaagaaaggaatttctagattatcagttggatgagctttcccggcagcgagct
ctgtgccgaggtggacgggaaatacagaggcaagaattagatgaaaacatttccaaagtt
tctaaggaaaggcaggaacttgcttctaaaattaaagaggttcaaggacgcccacagaaa
acacagagtatcatcatcttagagtcccatgtcatctgctgcacgttgagcacaagtggt
ggtttactacttgagtctgctttccgtgggcaagggggtgtccccttcagctgtgtcatt
gttgatgaggctggacagtcttgtgaaattgagactcttactccactcatccatcgctgc
aataagctcatcctagtaggagatcctaagcagctccctcccacagtcatctctatgaaa
gcacaggagtatggctacgaccagtcaatgatggctcgcttctgcagactgctggaagag
aatgtagaacacaacatgatcagcaggctgcccattctacagctcactgttcagtacagg
atgcatccagacatatgcctcttcccttctaattatgtttataacagaaacttaaaaaca
aatagacagacagaagccattcgatgttcatcagactggccatttcagccataccttgtg
tttgatgtcggagatggttccgaaagacgggataatgactcatatataaatgttcaagaa
ataaaactggtgatggaaataattaagcttattaaagacaaaagaaaggatgttagtttt
cgaaacattggcataataactcattacaaggcccagaagacgatgattcagaaggatttg
gacaaagagttcgatagaaaaggaccagcagaagtagatacagtggatgcattccagggt
cggcagaaggattgtgttattgtcacatgtgtcagagcaaatagcgtgcaaggttcaatt
gggaattcttctgtgcccggtaccctgtattgggacggagaattcctggcaagtttgcag
agattgaatgtcaccatcacacgagccaagtacagcctcttcatcctcggacatttgagg
accctgatgcaacttcttcctaggagcttttgtgtacacgtgaaccattcgccttttttc
agcccagaacccaagtatctacactgggctctcaaggaaaaccagcattggaatcagctg
attcaggatgctcagaagcgtggtgccattattaagacctgtgacaaaaactatagacat
gatgcagtgaagattctgaaactcaagcctgtgctacagagaagtctcactcaccctcct
accatagccccagaggtgtccagaccccagggtggtttgcccagcagcaagctagacagt
ggatttgccaagacatctgttgctgcttctctataccacacaccctctgactccaaggaa
actactcttactgttacttcaaaggaccctgaaagacctcctgttcatgaccaacttcgg
gacccacgactgctgaagaggatgggcattgaggtcaaaggaggaatattcctatgggat
ccacaaccctcgagcccccagcatcctggagcaacacctcctacaggggagtcgggcttc
cctgtcgttcaccaggacctgagccatgtacagcagcccgctgctgtagtggctgctctg
agcagccacaaacctcccgtgcagggtgaacctccagctgccagtcccgaggcttccacg
tgtcagagcaaatgtgatgacccggaagaggagctctgtcacaggagagaggccagggct
ttcagtgaaggggagcaggagaagtgtggttctgagacccatcacaccaggaggaactct
aggtgggacaagaggagactggagcaggaggacaacagttccaagaaaagaaagctttta
tag
DBGET
integrated database retrieval system
