KEGG   Pongo pygmaeus (Bornean orangutan): 129045259
Entry
129045259         CDS       T10128                                 
Symbol
PPP3CB
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
ppyg  Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg04010  MAPK signaling pathway
ppyg04020  Calcium signaling pathway
ppyg04022  cGMP-PKG signaling pathway
ppyg04114  Oocyte meiosis
ppyg04218  Cellular senescence
ppyg04310  Wnt signaling pathway
ppyg04360  Axon guidance
ppyg04370  VEGF signaling pathway
ppyg04380  Osteoclast differentiation
ppyg04625  C-type lectin receptor signaling pathway
ppyg04650  Natural killer cell mediated cytotoxicity
ppyg04658  Th1 and Th2 cell differentiation
ppyg04659  Th17 cell differentiation
ppyg04660  T cell receptor signaling pathway
ppyg04662  B cell receptor signaling pathway
ppyg04720  Long-term potentiation
ppyg04724  Glutamatergic synapse
ppyg04728  Dopaminergic synapse
ppyg04921  Oxytocin signaling pathway
ppyg04922  Glucagon signaling pathway
ppyg04924  Renin secretion
ppyg05010  Alzheimer disease
ppyg05014  Amyotrophic lateral sclerosis
ppyg05020  Prion disease
ppyg05022  Pathways of neurodegeneration - multiple diseases
ppyg05031  Amphetamine addiction
ppyg05152  Tuberculosis
ppyg05163  Human cytomegalovirus infection
ppyg05166  Human T-cell leukemia virus 1 infection
ppyg05167  Kaposi sarcoma-associated herpesvirus infection
ppyg05170  Human immunodeficiency virus 1 infection
ppyg05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ppyg05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ppyg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    129045259 (PPP3CB)
   04310 Wnt signaling pathway
    129045259 (PPP3CB)
   04370 VEGF signaling pathway
    129045259 (PPP3CB)
   04020 Calcium signaling pathway
    129045259 (PPP3CB)
   04022 cGMP-PKG signaling pathway
    129045259 (PPP3CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    129045259 (PPP3CB)
   04218 Cellular senescence
    129045259 (PPP3CB)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    129045259 (PPP3CB)
   04650 Natural killer cell mediated cytotoxicity
    129045259 (PPP3CB)
   04660 T cell receptor signaling pathway
    129045259 (PPP3CB)
   04658 Th1 and Th2 cell differentiation
    129045259 (PPP3CB)
   04659 Th17 cell differentiation
    129045259 (PPP3CB)
   04662 B cell receptor signaling pathway
    129045259 (PPP3CB)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    129045259 (PPP3CB)
   04921 Oxytocin signaling pathway
    129045259 (PPP3CB)
   04924 Renin secretion
    129045259 (PPP3CB)
  09156 Nervous system
   04724 Glutamatergic synapse
    129045259 (PPP3CB)
   04728 Dopaminergic synapse
    129045259 (PPP3CB)
   04720 Long-term potentiation
    129045259 (PPP3CB)
  09158 Development and regeneration
   04360 Axon guidance
    129045259 (PPP3CB)
   04380 Osteoclast differentiation
    129045259 (PPP3CB)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    129045259 (PPP3CB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    129045259 (PPP3CB)
   05170 Human immunodeficiency virus 1 infection
    129045259 (PPP3CB)
   05163 Human cytomegalovirus infection
    129045259 (PPP3CB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    129045259 (PPP3CB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    129045259 (PPP3CB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    129045259 (PPP3CB)
   05014 Amyotrophic lateral sclerosis
    129045259 (PPP3CB)
   05020 Prion disease
    129045259 (PPP3CB)
   05022 Pathways of neurodegeneration - multiple diseases
    129045259 (PPP3CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    129045259 (PPP3CB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    129045259 (PPP3CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ppyg01009]
    129045259 (PPP3CB)
Enzymes [BR:ppyg01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     129045259 (PPP3CB)
Protein phosphatases and associated proteins [BR:ppyg01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     129045259 (PPP3CB)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 129045259
NCBI-ProteinID: XP_054359735
LinkDB
Position
8:68792399..68851114
AA seq 525 aa
MAAPEPARAAPPPPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLV
KEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANT
RYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYS
ERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLL
WSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMY
RKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFT
WSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVF
SVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSF
EEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHTAQ
NT seq 1578 nt   +upstreamnt  +downstreamnt
atggccgccccggagccggcccgggctgcaccgcccccacccccgcccccgccgccccct
cccggggctgaccgcgtcgtcaaagctgtccctttccccccaacacatcgcttgacatct
gaagaagtatttgatttggatgggatacccagggttgatgttctgaagaaccacttggta
aaagaaggtcgagtagatgaagaaattgcgcttagaattatcaatgagggtgctgccatc
cttcggagagagaaaaccatgatagaagtagaagctccaatcacagtgtgtggtgacatc
catggccaattttttgatctgatgaaactttttgaagtaggaggatcacctgctaatacg
cgatacctttttcttggcgattatgtggacagaggttattttagtatagagtgtgtctta
tatttatgggttctgaagattctatacccaagcacattatttcttctgagaggcaaccat
gaatgcagacaccttactgaatattttacctttaagcaggaatgtaaaattaagtattcg
gaaagagtctatgaagcttgtatggaagcttttgatagtttgcctcttgctgcactttta
aaccaacagtttctttgtgttcatggtggactttcaccagaaatacacacactggatgat
attaggagattagatagattcaaagagccacctgcatttggaccaatgtgtgacttgtta
tggtccgatccttctgaagattttggaaatgaaaaatcacaggaacattttagtcacaat
acagttcgaggatgttcttatttttataactatccagcagtgtgtgaatttttgcaaaac
aataatttgttatcgattattagagctcatgaagctcaagatgcaggctatagaatgtac
agaaaaagtcaaactacagggttcccttcattaataacaattttttcggcacctaattac
ttagatgtctacaataataaagctgctgtattaaagtatgaaaataatgtgatgaatatt
cgacagtttaactgttctccacatccttactggttgcctaattttatggatgtcttcacg
tggtctttaccgtttgttggagaaaaagtgacagaaatgttggtaaatgttctgagtatt
tgctctgatgatgaactaatgactgaaggtgaagaccagtttgatgtaggttcagctgca
gcccggaaagaaatcataagaaacaaaattcgagcaattggcaagatggcaagagtcttc
tctgttctcagggaggagagtgaaagtgtgctgacactcaagggcctgactcccacaggg
atgttgcctagtggagtgttagctggaggacggcagaccctgcaaagtgccacagttgag
gctattgaggctgaaaaagcaatacgaggattctctccaccacatagaatctgcagtttt
gaagaggcaaagggtttggataggatcaatgagagaatgccacctcggaaagatgctgta
cagcaagatggtttcaattctctgaacaccgcacatgccactgagaaccacgggacgggc
aaccatactgcccagtga

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