KEGG   Podarcis raffonei (Aeolian wall lizard): 128402896
Entry
128402896         CDS       T09310                                 
Symbol
ARHGEF12
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
  KO
K07532  Rho guanine nucleotide exchange factor 12
Organism
praf  Podarcis raffonei (Aeolian wall lizard)
Pathway
praf04270  Vascular smooth muscle contraction
praf04625  C-type lectin receptor signaling pathway
praf04810  Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:praf00001]
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    128402896 (ARHGEF12)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    128402896 (ARHGEF12)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    128402896 (ARHGEF12)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:praf04131]
    128402896 (ARHGEF12)
Membrane trafficking [BR:praf04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    128402896 (ARHGEF12)
SSDB
Motif
Pfam: RGS-like PH_16 RhoGEF PDZ PDZ_6 PDZ_2 PH_13 SOS1_NGEF_PH Pept_S41_N_bact
Other DBs
NCBI-GeneID: 128402896
NCBI-ProteinID: XP_053223310
LinkDB
Position
15:complement(23194984..23282571)
AA seq 1533 aa
MSGTQSAITDRFPLKKPTRHGSILSRESPADKKQKVERCVSAQDFDPTDSSSRKTKCSSE
ESRSETYGLVQRCVIIQRDENGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNG
TLVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEMDPVAFGHMSPIMTSPHSP
GTSGNTERITSPVLMGEENNIVHSQKVEILRKMLQKEQERLQSLQEDYGRTPTPKLLKEI
QEAKKHIPQLQEQLSKATGSIQDGVLSSKSVAESLQISEVETESGDGLNKGDCSFGDGSQ
LNSDTAESPRGGLKERIYLDESPEKSETQDTDSQSSIGSPSSRIAPPIIGAEDDDFDGEQ
EQINGQCSCFQNIELLKSRPAHLSVFLHHVVSQFDPASLLCYLFADLYKQTNSKETRRVF
SEFNQFFLDRAANLKVPVPEEISADLEKRRLDLIPEELHRHYIQTMQDKVFPEVQRHLED
FRQKRSMGLTMAEGELAKLDAERFRDRSTLEKERACAEQIITKIEEVLMTSQPIEEEKSS
SIQYVVLTYMKHLGVRVKEPRGLDQKRRIGFLPKIKQSIKKEKEGDEKKRRVFPNILGPP
RRPSRHDSYAIGRAMEMQKQRHPKHLSTPSSVSPEPQDSVKMRQSGSSDGTDAAYPPANL
MSPQAAGTFLSQEGSKDSETGSKQVGETPSSSDSLVGTPRTPNTVFDFPSPPLDHLQEEE
GEFDRLAESGTPKSFRKMDSVGAVDNQSEDELFDFDMETDPPNWQQLVSREVLLGLKPSE
IKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILPHSDLRKIFSNVEDILQLHAGL
NEQMKAVRKRNETSVIDQIGEDLLTWFSGAGEEKMKQATGTFCSNQPFALEVIKSRQKKD
SRFQTFVQDAESNPLCRRLQLKDIIPTEMQRLTKYPLLLDNIAKYTEQPGEKEKVKKAAD
HCRQILNYVNQAVKEAENKQHLEDYQRRLDLSYLKQLEGPMLDEFRNLDLTKKKMIHEGP
LTWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASAAECKHIFSPVIKLNTV
LVRQVATDNKAFFVISMSENGAQIYELVAQTVSEKTVWQDLIARMAGTVKVGRGRSVIPF
PPSGPCEEDHEEEDQQKLKEEQATPDSSMQSPDKDMGLESPLMAKVQSPSAAMSEKLEEE
ELLEADRQFGEKPAAELLIKESSEHYSHTSPEHLFQSSEDRWALDALRNLGLLKKLLMEQ
LGMSEKESSEGWQRIARHRTICQRTQVESCVQRGLQYSDNDKTSLSGASRTPSGMGTNNF
GPCCSHRTSSEFMQPGDTVSNSSQLMDPLSTKPDTPTTEPEVIGSEDGGEHFFDAREAHS
DENQSEGEVAERKEEEEVQLRISGNYLILDGYGTVQESSTDEEVTSLVLQCTAGNSTMDS
THQPPSLQDTRTDGGSLAFAEELMASHWEAAKESSSGVLRPPFSVESCALIMHYIQKIEA
NLEHLKEVEENYATLLQQRLAGTAPTDEHSDKS
NT seq 4602 nt   +upstreamnt  +downstreamnt
atgagtggcacacagtctgcaatcacggacaggtttcccctcaaaaaacctacaagacat
ggcagcattctgagcagagagtctccagcagacaagaagcagaaggttgaacgctgcgtc
agtgcccaggacttcgaccctacagatagctcctccaggaagacaaagtgtagctcggag
gagagtagatccgagacgtatggtcttgtccagcgttgtgttattatccagcgagatgaa
aacggatttgggctgaccgtcagtggagacaatcctgtctttgtgcagtccgtcaaagaa
gatggagcagccatgcgggctggggttcaaactggtgaccgaattattaaggtgaatggg
actctggtaacccactcaaaccatttggaggtggtgaagctgataaagtcgggctcctat
gtagcactcactgtgcaagggcgcccacctgggtcgccccagattccactggctgattct
gagatggatccagtagcatttggacatatgtctcccatcatgacatctccacactcgcct
ggaacatctggaaacacagagagaattaccagcccggtgttgatgggggaggaaaataat
attgttcatagccagaaggtggagattttgaggaagatgcttcagaaggagcaggagagg
ctacagtccttgcaagaagattacggccgcactcccactccaaaactgctcaaggagatc
caggaagccaagaagcacatccctcagctgcaggaacagttgtccaaggcaacaggctct
attcaggatggagttttatcttccaagtctgtggcagagtctttgcagatcagcgaggta
gagactgagagcggggatgggctgaacaaaggagactgcagttttggtgatggctcccag
ttaaatagtgacacagctgagagtccccggggtggcctgaaggaacgaatctatctggac
gagagcccagagaagagtgagacacaagatactgactctcaatccagtattggaagtccc
tccagtcgtattgcacctccaatcataggagcagaagatgatgactttgatggtgaacag
gagcagatcaatgggcagtgcagctgtttccagaatatagagctgttgaaatctcgccct
gctcacctgtctgtcttcctgcatcatgtcgtgtcccagtttgaccctgcttcattgctt
tgctatctttttgcggacctgtacaaacaaacaaactccaaagagactcggcgtgtcttt
agtgagtttaaccagttcttcttggatcgagctgcaaatctgaaagtcccagtcccagaa
gaaatttctgcagatctagaaaagagaaggctagacttgattcctgaagaattgcaccgc
cactatattcaaactatgcaagataaagtttttcctgaagtccagaggcaccttgaagat
tttagacagaaacgcagcatggggctgaccatggcagaaggagagctagccaagctggat
gcagaacgttttcgtgaccggagcacactggagaaggagagagcatgtgcggagcagatc
attaccaaaattgaagaagtgctgatgacgtctcaacccattgaagaagagaagagttca
agcatacaatatgtggttctcacctacatgaaacatcttggtgtgagagtcaaagagccc
cgggggctagatcagaagcgacggattgggttcctgccaaaaataaagcagagtataaag
aaagagaaggaaggagatgaaaagaagaggagagtcttccccaatattctgggaccccca
aggaggccaagccgccatgacagctatgcaataggcagagccatggaaatgcaaaagcag
cgccatccaaagcacttatccacaccttcctccgtcagtccagagccacaagactcagtc
aagatgcgccagagtgggtccagcgatggcacagatgcagcctacccacctgctaacctc
atgtctccacaagctgctggaacttttctttcccaggaagggagcaaggacagtgaaaca
gggtcgaagcaagttggagaaactccatcgtctagtgactctctggttggtacacctcgt
acacctaataccgtctttgatttcccatctccaccacttgaccatttgcaggaagaggaa
ggagagtttgacaggttagcagaatcaggaacaccaaaatctttccgcaagatggacagt
gtgggtgctgtggataatcagagtgaagatgagctctttgattttgacatggagacagac
ccacccaactggcagcagcttgtgagccgtgaggtgctgcttggcttgaaaccctctgag
attaaacggcaggaagtgattaatgagttattttacactgagcgtgctcatgtccgaaca
ctgaaggttcttgatcaggtcttctatcaacgtgtgtcccgtgaagggatcttacctcac
tctgacttgcggaaaatattttcaaatgtggaagatatcctccagctccatgctggattg
aatgagcagatgaaagcagtgaggaaaaggaacgaaacgtcagttattgatcaaattgga
gaggacttgttaacttggttcagtggagcaggggaggagaaaatgaaacaagccactggc
actttctgtagcaaccagccctttgctctggaggtgatcaagtcacggcagaaaaaggac
tctcgcttccagacttttgtccaggatgctgagagcaatccactctgtcgccgactgcag
ctgaaagatataattcccactgagatgcagaggctgaccaaatatccccttctgctggat
aacattgcaaagtacacagaacaacctggggagaaagagaaagtgaagaaagcagcagat
cactgtcggcagatcctcaattatgtgaaccaagctgtcaaagaagcagaaaataagcag
catttggaagactaccagcgccgtcttgatttgtcctacttgaagcagttggagggccct
atgctggatgaattcaggaatttggatttaaccaagaagaagatgatccatgaagggcct
ctgacgtggaaggtgaatcgggacaagacaattgatctctacacgctgctgttggaggat
attctggtgcttttacagaaacaagatgatagactggtgctgagatgtcacagcaagatc
ctggcttctgctgcagagtgcaagcatatattcagccctgtcatcaaactgaatacggtg
ctggttcgccaggtggccacagataacaaagccttctttgtcatctccatgtcagagaat
ggagcccagatatatgaattggtggcacagacggtttctgaaaagactgtgtggcaggac
ctcatagcacggatggcaggaacagtgaaagttggacgaggtagaagcgtaattccattt
ccgccatctgggccatgcgaggaagatcatgaggaggaagatcagcagaaattaaaggaa
gaacaagctactcctgatagcagcatgcagagtccagataaagatatgggactggagtct
cctctgatggcgaaggttcagtctccttcagcagcaatgtctgagaagctggaagaggag
gagctcctggaggcagacaggcagtttggagaaaaaccagcagcagagttgctgatcaaa
gagtcatctgagcactacagccacacaagtccagagcacttgttccaaagttcggaagac
cgatgggcattggatgcactaagaaatttgggcttattgaagaaattgctaatggagcag
ctgggcatgtctgagaaggagtcttccgaaggctggcagcgtattgccaggcataggaca
atttgtcagaggacccaagtggagagttgtgtccagagaggactacagtactcggacaat
gacaagacatccctttccggggccagtaggacaccctctggcatgggaacaaataatttt
ggaccttgttgcagtcatcggacttcaagtgaattcatgcaaccaggggacactgtgtca
aacagcagtcagttaatggaccccttgagcacaaagccagataccccaaccactgagcct
gaagtgataggttctgaggatggtggagagcacttttttgatgctcgtgaagcccacagc
gatgagaaccaatcagagggtgaagtggcggaaaggaaggaggaagaagaggtgcagttg
cggatctcaggaaattatttgatccttgatggatatggcacagtacaggagagctccaca
gatgaggaggtaacttcgctggttctacagtgcactgcaggcaacagcacaatggactct
acccaccaaccaccatctctgcaagacacccggacagacggaggaagcttggcatttgca
gaggaattaatggcctcccactgggaagctgctaaggaatccagctcaggtgtactaagg
cctcccttctctgtggagtcttgtgccctgataatgcattacatccagaagatagaagcc
aaccttgaacacttaaaggaagtggaggagaactatgctactcttcttcaacaaaggctg
gctggaacagcccccacagatgagcactcagataaaagttag

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