Podarcis raffonei (Aeolian wall lizard): 128410199
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Entry
128410199 CDS
T09310
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
praf
Podarcis raffonei (Aeolian wall lizard)
Pathway
praf00270
Cysteine and methionine metabolism
praf00480
Glutathione metabolism
praf01100
Metabolic pathways
praf01240
Biosynthesis of cofactors
praf04216
Ferroptosis
Module
praf_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
praf00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
128410199 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
128410199 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
128410199 (GCLC)
Enzymes [BR:
praf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
128410199 (GCLC)
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Motif
Pfam:
GCS
Motif
Other DBs
NCBI-GeneID:
128410199
NCBI-ProteinID:
XP_053237028
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Position
3:complement(34492252..34518310)
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AA seq
634 aa
AA seq
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MGLLSQGSPLSWEKTQRHAEHVRKHGILQFLHIYRAVGERHKDVLKWGDEVEYMLVVFDH
KNKRAQLSLTGGDVLHTLQEKGERVNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRLEAASVLKQNEAVCTVTSFPRLGCPGFTIPECVPTPVETGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEGARAVKPDHVYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAAAPFYRGYVTDIDCRWGV
ISASVDDRTREERGLEPLKNNRYRINKSRYDSIDSYLSECGEKYNDIDLTVDKEIYEQLV
KEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAV
RQGMFYFRKDISKGGNAVVDGCGPAQNGTETDSEEYTLMSIDTIINGKEGVFPGLIPILN
SYLENMEVDVDTRCSILNYLKLIKKRASGELMTAARWMREFVANHPAYKHDSVITEEINY
SLIWKCYQIAEEQFECPELLGNKVKYSGNKTSTF
NT seq
1905 nt
NT seq
+upstream
nt +downstream
nt
atggggctcctgtcgcagggctcccctctgagctgggagaagacgcagcgccacgcggag
cacgtgcgcaaacacggcatcctgcagttcctgcacatctaccgggcggtgggcgagagg
cacaaggacgtgctcaagtggggcgacgaggtggaatacatgttggtagtatttgaccat
aaaaacaagagagcgcagttgtccctaactggaggagacgttcttcatactttgcaagaa
aaaggagaaagagtaaacccaaaccatccaactctgtggaggccagaatatggaagctat
atgattgaggggacccctgggcaaccctatggagggacaatgtctgaatttaacactgtg
caagacaacatgagaaagcgacgcctggaggctgcttctgtgctgaaacaaaacgaagct
gtttgcactgtgacatcatttccaagactgggctgtccaggatttacgataccagagtgt
gtgcctacccctgttgagacaggagcttccaagtctctcttcttcccagacgaagccatt
aacaaacaccccaggtttagtactttaacaagaaacattcgacacagaagaggagaaaaa
gtagtgataaacgtaccaatatttaaagacaagaatacgccgtcgccgttcatagaaaca
ttccctaatgatgatggtgaaggggcaagagcagtcaagcctgaccatgtctacatggat
gccatggggtttggaatgggcaactgctgccttcaggtaacattccaggcttgcagcatc
tctgaagcaagatacctttatgatcagctagcgaccatctgtcccatcgtgatggcatta
agtgcggcagctcccttctacagaggctacgtgacagatatcgattgccgttggggagtg
atatctgcctccgtagatgacagaacgagggaggagaggggattggagccgttgaagaac
aaccgctacagaatcaataaatccagatacgattccatagacagttatctctctgaatgt
ggtgaaaaatacaatgacattgatttgacggtagataaagaaatctacgagcagttagta
aaggaaggcattgaccatctgttggcccaacacattgctcatttatttatccgtgatcct
ttgactctgttcgaagagaaaatacatctggatgatgcaaatgaatctgaccactttgag
aatattcagtcaacaaactggcagacaatgagattcaaaccaccgcctccgaattcagac
attggatggagggttgagttcagaccaatggaggtccagttaacagactttgaaaattcc
gcctacgttgtgtttgtagtgttgctgactcgagtcattctctcctacaaactggatttt
ctcattcctttgtccaaggtggatgagaacatgaaagtagctcagaaacgggatgctgtt
cggcaaggcatgttttatttcagaaaagacatttctaaaggtggcaatgctgtagtggac
ggatgtggaccagctcaaaatggtacagagacagattctgaagaatataccttaatgagc
atagatacaataatcaatggaaaggaaggagtatttcctggattaattccaattttgaac
tcttaccttgaaaatatggaagtggatgtagatacaaggtgcagcattctaaactacctg
aaactcattaaaaagagagcatcaggagaattaatgacagccgctcgatggatgcgagag
ttcgttgcgaaccacccagcatacaaacacgacagtgtgattaccgaagagattaattac
agcctgatttggaaatgctaccaaatcgccgaagagcaatttgaatgccctgaactgctt
ggtaacaaagtaaaatacagcggaaataaaaccagcactttttga
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