Podarcis raffonei (Aeolian wall lizard): 128410573 Help Entry 128410573         CDS       T09310                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism praf  Podarcis raffonei (Aeolian wall lizard) Pathway praf04020   Calcium signaling pathway praf04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:praf00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     128410573 (RYR3)    04020 Calcium signaling pathway     128410573 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:praf04040]     128410573 (RYR3) Ion channels [BR:praf04040]  Voltage-gated cation channels   Ryanodine receptor    128410573 (RYR3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 DUF6161 Motif Other DBs NCBI-GeneID:  128410573 NCBI-ProteinID:  XP_053238000 LinkDB All DBs Position 1:40852508..41125613 Genome browser AA seq 4859 aa AA seqDB search MAEGGEAGEDEIQFLRTDDEVVLQCVANIHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVP PDLCICNFVLEQSLSVRALQEMLANTGDNSSEGAAQGGGHRTLLYGHAILLRHSFSGMYL TCLTTSRSQTDKLAFDVGLQENAAGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSER YLHLSVAYGNIQVDASFMQTLWNVHPTCSGSSIEEGYLLGGHVLRLFHGHDECLTIPSAE QNDSPHKRLFFEAGGAGVRARSLWRVEPLRISWSGSNIRWGQPFRLRHITTGQFLALTEE LGLVLLDKEKADTKSTSFCFRASKEKLDSAHKRDIDGMGVPEIKYGDSVCFVQHVTSTLW LTYKAQDAKTTRLGPLKRKVILHQEGHMDDGLTLQRCQHEESQAARIIRNTTRLFSQFIS GNNRTSTPITLPIEEVLQTLQDLITYFLPPEEELEHEDKQNKLRSLKNRQNLFKEEGMLA LVLNCIDRLNVYYSTAHFTGIGREENGAAWKEILNLLYKLLAALIRGNRNNCAQFSNNLD WLISKLDRLESSSGILEVLHCILIESPEALNLIEEGHIKSIISLLDKHGRNHKVLDVLCS LCLCNGVAVRANQNLICDNLLPRRDLLLQTRLVNDVTSMRPNIFLGIADGSAQYKKWYFE LIIDQVDPFLTAKPTHLRVGWASALGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSGR VPRAVASVNQHLLASEDVVSCCLDLGAPSISFRINGQPVQGMFENFNTDGLFFPVVSFSA GVKVRFLMGGRHGEFKFLPPAGYVPCYEALLPKEKMKLEPVKEYKRDLDGVRDLLGTTQF LSQTNFIPCPIDTSQIALPFHLEKIRDKLAENIHELWGMNKIELGWTYGKIRDDNKRQHP CLVEFSKLPETEKNYNLQMSTETLKTLLALGCHVVHINPGAEEDLQKIKLPKNYMMSNGY KPAPLDLSEVKLLPSQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLVPYT LLDERTKKSNRDSLREAVRTFAGYGYNIEPPDQEIADQTVEKVSIDKIRFFRVEQSYAVK TGKWYFEFEAVTGGDMRVGWARPGCRPDIELGADDQAFVFEGSKGQRWHQGSGFFGRNWQ PGDVVGCMINLDDKSMIFTLNGELLITNKGSELAFADFEIDNGFVPICSLGLSQIGRMNF GRDASTFKYYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKDHPHIEVTRIDGNI DSPPRLKVTHKTFGTQNSNADMIYCRLSMPIEFHSSFNYSTGLELIDSFQKRKQNQEIPV HATTYYYSVRIFAGQDPSVVWIGWVTPDYHFYSEHFDLNKNCTVTVTLGDERGRVHESVK RSNCYLVWGGETSVNSQRSGRGNVDLEIGCLVELATGMLSFTANGKELGTFYQVEPNTKL FPAAFLQPTSTNLVQFELGKLKNTMPLSAAIFKSEERNPIPQCPPRLDVQTITPVVWSRM PNSFLKVEAEKVSDRHGWVVQCLEPLQMMALHIPEESRCIDILELCEQEDLMRFHYHTLK LYSSVCALGNNRVAHILCSHVDVSQLFYTIDNRYLPGLLRSGFYDLLISIHLEYSKEAKL MMNNEFIIPITDETRKIKLFPDESKRHGLPGVGLSTCLKPGFKFSTPCFVLSHEDHQKPS PEIPLEMLKSRAISMLTEAVYCSGTHIRDPVGGEVEFQFVPVLKLIGTLLIMGVFDDHDV KQILLLIDPCVFGETKEEVMEKAEKEDVAQIEEKAIEAGEKAIREPKTPIKGLLQTRLPE SVKLQMCELLNYFCDCELKHRVEAIVSFADTYVSKLQYNQKYRYNELMQALNMSAALTAK KTKEFRSPPQEQINMLLNFQLGEDCPCPEEIQEELYEFHDDLLIHCGIPLEGEEEEEEDL SWTGKLRSLVYKIKGPPKTEKREPTEEEEKYPTTLKELISQTMVRWAQEDQIQDPELVRI MFNLLRRQYDSIGELLQALRKSYTISATSVQDTINLLAALGQIRSLLSVRMGKEEELLMI NGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKSQIAFPKMVASCCRFLCYFC RISRQNQKAMFEHLSYLLENSSVGLASPSMRGSTPLDVAAASVMDNNELALALEEPDLEK VVTYLAGCGLQSCPMLLATGYPDIGWNPIEGERYLSFLRFAVFVNGESVEENASVVVKLL IRRPECFGPALRGEGGNGLLAAMQGAIKISENPALDLPSQGYKRELLEEDEEEEEVVHMG NAIMSFYSALIDLLGRCAPELHLIQTGKGEAIRIRSILRSLVPTEDLVGIISIPLKLPAV NKDGTVTEPDMSASFCPDHKAPMVLFLDRVYGIKDQSFLLHLLEVGFLPDLRASASLDTV SLSTTETALALNRYICTAVFPLLTRCASLFSGTEHYVSLIDSTLHTMYRLSKGRSLTKAQ RDTIEECLLAICHHLRPSMLQQLLRRLVFDVPLLNEYCKMSLKLLTNHYEQSWKYYCLPS GWGNYGIAAEEELHLSEKLFWGIFDSLSHKKYDPELFRMALPCLSAIAGALPPDYLDTRI TSVLEKQTSVDADGNFDPKPINTVNFTLPEKLEYIVNKYAEHTHDKWACDKNNSGWKYAS SLDENVKTHPLMRPFKTLTEKEKEIYRWPARESLKTMLAMGWSLERIKEGNSMVQQRESE KLRSISQSSQGNGYNPAPLDLSNVVLSREIQGMVEVVAENYHNIWAKKKKTELESKGGGS HPLLVPYDTLTAKEKSRDREKAQELFKFLLVNGIVISRGLSGMEMDASSMEKRFAYKFLK KILKYVDSAQEFIAHLEAIVTSGKTEKSPHDQEIKFFAKVLLPLVDQYFTNHCLYFLSSP TKPLSSSGYASNKEKEMVASLFCKLAALVRHRISLFGSDAATMVSCLHILAQTLDTRTVM KSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNINYTTVALLPVLT SIFEHVAQHHFGTDLLLGDVQVSCYRILCSLYSLGTGKNIYVERQRPALGECLASLAAAI PVAFLEPSLNLYNPLSVFNTKTARERAILGMPETVEEMCPEIPHLDGLMKEINSLAESGA RYTEMPHVIEVILPMLCNYLSYWWERGPENAESTGPCCTMVTSEHLSIILGNILKIINNN LGIDEATWMKRIAVYAQPIISKARPDLLKSHFIPTLEKLKKKAIKIVMEEEQLKADSKTD TQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSNWLKKPDADSDELFRMVAEVFILWC KSHNFKREEQNFVIQNEINNLAFLTGDSKSKMSKSGGHDQERKKSKRRGDLYSIQTSLIV AALKKMLPIGLNMCTPGDQELISLAKFRYSCKDTEEEVKEHLRNNLHLQEKSDDPAVKWQ LNLYKDVLKADEPVDPEKIVQRVQRISAAVYHLEQVEQPLRSKKAVWHKLLSKQRKRAVV ACFRMAPLYNLPRHRSINLFLHGYQKYWIETEEYSFEEKLVQDLATPPQKSEEEEEETEK HPDPLHQIILHFSRNALTERSKLENDPLYTAYSAMMAMSCQSGESDDDEEEKEKTFEEKE MEKQKTLYQQSRLHERGAAEMVLQMISASKGEMGHMVVETLKLGIAVLNGGNSVVQQKML DYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRERGEKVLQN DEFTKDLFRFLQLLCEGHNNDFQNYLRTQMGNTTTVNIIISTVDYLLRLQESISDFYWYY SGKDVIDESGQRNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFA NMQMKLSQDSSQIELLKELLDLLKDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSSNVEM ILKFFDMFLKLKDLTSSEAFKEYDPESKGIISKKEFQKAMEGQKQYTQSEIEFLLSCAET DENDMFNYADFVERFHEPAKDIGFNVAVLLTNLSEHMPNDSRLQTLLDPAECVLNYFEPY LGRIEIMGGAKKIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEQEKMELFVNF CEDTIFEMQLASQISESDIVDRPEEEEDEPCYVREIGEDEKGEQSLESASAFAMACVAIK KNAATVFKMIRLKNLRKQYRKVRKMTVKELVKVSFSFLWMLFVGFFQMFLTILCSIFQIL WSTVFGGGLIEGAKNIRVTKILGDMPDPTQFGIHDDVLEAEKVEVTEHGITAEIVQFVKN EKGETDILSDIFGIHTKKESGSKHGHAVGLGDIADIIGSDTPPSLESAVRKKKKAQTPEI AKDDESETRTESEKADMEDGEKQDKIKDDMYSEHMELEEPRKRKRKRGQKIEKPDAVMAN FFKVLEVYQTKMLHFLARNFYNLRFLALFVAFAINFILLFYKVTEEPFEEMEEDSDLWHS LEEEEDEDGVVFFVLQESTGYMAPTLRALAVIHTIISFVCVIGYYCLKVPLVVFKREKDI ARKLEFDGLYITEQPSEDDIKGQWDRLVINTPYFPNNYWDKFVKRKVINKYGDLYGAERI AELLGLDKNALDFSPVEHTELEEASLVLWLSSIDAKYHIWKLGVVFTDNSFLYLAWYTTM SILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNF FRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEMYRIVFDI TFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTTPHGFEMH TLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14580 nt NT seq  +upstreamnt  +downstreamnt atggctgaagggggcgaagcaggggaagatgaaatacagttcctacgaactgatgatgaa gtagtgcttcagtgcgttgccaacatccacaaagagcagcgcaagttctgcctggcagct gaggggctcgggaaccgcttgtgctttttggaaccaacttcagaagcaaaatatgtccct cctgacctttgcatctgtaactttgtactggagcagtctttatctgtcagggccctccaa gagatgcttgccaatacaggagacaattccagcgaaggggcagctcaaggaggtggtcac agaacactgctgtatggccatgctatacttcttcgtcattcatttagtggaatgtatttg acatgtttgactacttcgagatctcagacggataaacttgcatttgatgtggggctacaa gagaatgcagccggtgaggcatgctggtggaccatacatcctgcttctaaacaaaggtct gaaggagaaaaggtacgaattggagatgatcttatcctggttagtgtgtcctccgaaagg tacctgcatctttctgtagcatatggaaacatacaggtggatgcttcctttatgcaaaca ctatggaatgtgcatcccacttgttcaggaagtagcattgaagaaggatacttactcggt gggcatgtattacgtttgtttcacggccatgatgagtgtttaacaattccatctgcagaa cagaatgattcaccacacaagcggttgttttttgaagcagggggagctggtgtccgtgca aggtcactgtggagagttgaaccgcttcggataagctggagtggaagtaacatccgctgg ggccagccttttcgccttcgacatattacaacggggcagtttttggccctaactgaagag ctgggtcttgtcttgttagacaaagaaaaagctgacacaaaatcaacttccttttgcttt agagcatcaaaagaaaaactggattctgctcacaaacgtgacatagatggcatgggagtt cctgaaataaagtacggtgattctgtttgttttgtgcaacatgtaaccagcactttgtgg ctcacttacaaagcacaggatgctaaaacaactcgtttaggaccactaaaaagaaaggtt atattacaccaagaaggacacatggatgatggtctcacattacaacggtgtcaacatgaa gaatcccaggctgctcgaatcattcgcaacacaacaagattatttagtcagtttataagt ggaaacaacagaacttcaactcctatcactctgcctattgaagaggtattgcagactctg caagacttgataacatattttctgcctccagaagaagagttagaacatgaagataaacaa aacaagcttcgttcactcaagaacagacagaacctattcaaggaagaggggatgctggca ctggtcttgaactgcattgatcgtttaaacgtctactatagcactgctcactttacaggg attggtagagaagaaaatggtgcggcatggaaagaaattctgaaccttctttacaaattg ctagctgctctcattcgtggtaacagaaataattgtgctcagttttcaaataatcttgat tggctaattagtaaattagatagactagaatcttcctcaggtattttggaggtgttgcac tgcatcctgattgaaagcccagaggctttaaatttgatagaagaaggccatatcaagtct ataatctcgctgctggataagcatgggcgcaaccataaggttctcgatgtgctttgttct ctttgtctttgtaatggagtagcggtgcgcgctaatcagaacttaatctgtgacaatctt cttcctcgaagagatctgctcttgcaaacacggcttgtgaatgatgtgacaagtatgcgg ccaaacatatttcttggaattgctgatggctcagcacaatataagaaatggtactttgaa ctaataattgatcaagtagatccatttttgacggcaaaacctacacatctacgggttggc tgggcctcagctttaggctatgctccttatcctggaggtggggaaggatggggaggcaac ggtgttggtgatgacctatactcatatggctttgatggacttcatctatggtctggtcga gtgcccagagcggtggcatctgtcaatcagcatttgctagcatctgaggacgtggtcagc tgctgcttggatttaggagcacccagcatttctttccgcattaatgggcagcctgtgcaa ggaatgtttgagaacttcaatacggatggactttttttccctgtggtgagcttctcagct ggtgtcaaggtacgtttcttgatgggtgggcgccatggagagttcaaatttctacctcct gctggctatgtgccttgctatgaagctttgcttccaaaagagaagatgaaactggaacca gttaaagaatataagagagatttggatggagttagagatttgcttggtaccacacaattt ctctcccaaactaatttcatcccttgtccaatcgacaccagccagattgctttgcctttc catcttgagaagatcagagacaagcttgctgaaaatatccatgaactctggggaatgaat aaaatagaacttggctggacttatggcaagatacgagacgataataaaagacaacaccct tgtctggtggaattttcaaaactacctgaaacagagaagaactataaccttcaaatgtca acagaaaccctgaaaacgcttttggcccttgggtgccatgttgttcacattaatccagga gcagaggaagatcttcagaaaatcaaacttccaaaaaattacatgatgtcaaatggctat aagccagcacctctagatctttctgaagtgaaattgctgccttcgcaagaagtgttggtt gacaaacttgcagagaatgcacataacgtctgggcaaaagacagaataaaacaaggttgg acatacggcattcagcaggatctcaaaaacaaacgaaatccccgactggtgccttataca ttattagatgagcgtactaaaaaatcaaacagagatagccttcgtgaagctgtccgcacc tttgctggttatggatataacattgaaccaccagatcaagaaatagctgaccaaacagta gaaaaagtgagcattgacaagatacgtttcttcagagtagagcagtcttacgcagttaag actggaaagtggtattttgaatttgaagctgtaacaggaggagatatgcgtgttgggtgg gcgaggccaggctgtcggcctgacatagaattgggtgctgatgaccaagcatttgtcttt gaaggcagcaagggtcaacgttggcaccaggggagtggattctttggacgaaattggcaa ccaggagacgtagtgggttgtatgataaatctagatgacaaatcaatgatatttactctg aatggagagttgcttataaccaataaaggttcagaacttgcttttgctgactttgaaata gataatggctttgtccccatatgctcattgggtctgtctcagattggacggatgaatttt ggaagagatgccagcacctttaagtattatacaatgtgtggtctacaggaaggctttgaa ccttttgctgtcaacatgaacagagatgttgctatgtggttcagcaaacgtttaccaaca tttgtcaatgtaccaaaagaccaccctcatattgaggtaacaagaattgatgggaacatt gacagtcctcctcgcttaaaagttacccataagacatttggaacacagaatagtaatgca gacatgatatattgtcgcttgagcatgccaattgaattccactcatcttttaactacagt actggtttggaactgattgatagtttccaaaaaagaaaacagaaccaggaaatacctgtt catgccacaacatactactactcagtgcggatctttgcgggccaagacccatctgttgtc tggattggctgggtaacacctgattaccacttttacagtgaacattttgacttaaataag aactgcacagtaacagttactttgggagatgaaagaggaagagttcatgaaagtgtaaaa cgtagcaattgctacctggtctggggaggagaaacatctgttaattcacaaagatctggt cgtggtaacgttgatttagaaattggatgccttgttgaattggctactggaatgttgtca ttcacagccaatgggaaagaactgggaactttctaccaggttgaaccaaacacaaaatta tttccagcagcttttttacagcctacgagcacaaaccttgtacagtttgaactgggtaaa ttaaagaacactatgcctttatcagcagcaatctttaaaagtgaagagagaaaccctatt ccccagtgccctcctcggctggatgttcaaactatcacacctgttgtgtggagcagaatg ccaaacagtttcctgaaagtagaagctgagaaagtcagtgaccgccatgggtgggtggtc cagtgcctggaacctttgcagatgatggctcttcatattcctgaagaaagcaggtgtatt gatattttagagctatgtgaacaagaggacctgatgaggttccactaccacactctaaaa ctgtatagttctgtttgtgcattgggtaataacagagtagctcatatactttgcagccat gtggatgtttctcagttattttatacaatagataatcgatatttacctggactcttgcgt tctggattctatgacttacttatcagcattcatttagaatactccaaggaagcgaaactc atgatgaacaatgaatttataattccaatcacagatgaaaccagaaaaatcaaattattt ccagatgaatcaaagagacatggtttgcctggcgttgggctcagcacctgcttgaaacca ggtttcaaattctctaccccttgttttgttttgtctcatgaggatcatcagaaacctagt ccagagataccactcgagatgcttaagtcaagagctataagcatgctaacagaagcagtc tactgcagtggaacacacatacgagaccctgttgggggggaagttgagttccagtttgtt cccgttctgaaacttataggaacattgctcataatgggagtttttgatgatcatgatgtc aaacagattttactcctcattgatccatgtgtgtttggtgaaaccaaagaagaagtaatg gaaaaagcagagaaagaggatgttgcacaaatagaagaaaaagctatagaggctggagaa aaggcaatcagggagcctaaaaccccaataaaaggcttgctgcaaacaagattgcctgaa tctgttaaactccagatgtgtgagctattaaattatttctgcgactgtgagctgaaacac agagtggaagccattgtatcattcgcagatacttacgtctcaaagttgcagtacaatcag aaatatagatataatgaactcatgcaagccttgaatatgtctgctgctttaacagctaag aagacaaaggaatttcgctctcctcctcaagagcagattaatatgttgctaaactttcaa ctgggagaggattgtccttgcccagaggagattcaggaagagttatatgagtttcacgat gatctcctaatccattgtggtatcccattagagggagaagaggaagaagaggaagatctg tcatggactggcaagctacgttcattggtatataaaataaaaggaccgccaaaaacagaa aagagagaacctacagaggaagaagaaaaatatcccacaactctgaaggagttaatatct caaactatggttcgctgggctcaagaagatcagatccaagacccagaattagttcgtatt atgtttaacctccttcgaaggcagtatgacagcattggcgagctgcttcaggctctgagg aaatcctacactataagtgctacatctgtgcaagacacaatcaacttattagcagcgctg ggtcaaattcgttcccttctcagcgtcagaatgggaaaagaagaagaattgcttatgatt aatggccttggagatataatgaacaacaaagtattttatcagcatcctaacttaatgaga gtcctgggtatgcatgagactgttatggaagtaatggtaaatgtgcttggaggagacaaa tctcagatcgcttttccaaaaatggtagcaagttgttgtcggttcctgtgctatttttgt cgaatcagtcgccagaaccaaaaggctatgtttgagcatctaagctacttacttgaaaac agcagtgttggacttgcttctccttcaatgaggggttccactccacttgatgtagcagct gcctcagtaatggacaataatgagcttgcactggcgctggaggagccagaccttgagaaa gttgtaacgtacttggcaggctgtggtctccagagctgccccatgcttttagcaacagga tatcctgacattggttggaatccaatagagggtgaacgatatctgtcattcttaagattt gctgtttttgttaatggtgaaagtgtagaggaaaatgccagtgttgttgtcaagcttcta attcggcgtcccgaatgttttgggccagctctgagaggagaaggaggaaatggtttgttg gctgctatgcaaggagcaattaagatatctgagaacccagctcttgatcttccctctcag ggatataagagggaacttcttgaagaagatgaagaggaggaggaggttgtgcatatgggc aatgcaattatgtctttctactcagctcttatagatttgcttgggcgttgtgcaccagaa ttgcatctcatccaaactggaaaaggtgaagctattagaatacgttccatcctgcgttcc ttggtgccaactgaagatttggttgggattataagcatacctctaaaattgccagcagta aataaagatggaactgttacagaaccagacatgtctgcaagtttctgccctgaccataag gcacccatggtactttttctagatcgtgtctatggtataaaggaccaaagcttccttctc cacctcctggaagttggatttttaccagatttaagagcaagtgcctcattggatacagtt tctttgagtactacagagacagctcttgctctaaatagatatatttgtacagctgtgttt ccattactcacacggtgcgcttctctcttttcggggactgagcattatgtctctctgatt gattccacacttcataccatgtatcgactatccaaaggacgctctcttaccaaagcacag agagacaccattgaagaatgtttacttgctatctgccatcatttacggccttctatgcta cagcagctattacgacggctggtttttgatgtacccttacttaatgaatattgtaaaatg tcacttaagctgctaacaaatcactatgaacaaagttggaaatattattgcttgccttct ggatggggaaattatggaattgcagctgaagaagaattacatttatctgaaaaacttttc tggggaatatttgattccctctctcataagaagtatgatccggagcttttccgaatggcc ttgccttgtttaagtgcaatagctggggctttgccaccagattatttagacacccgaatt acctcagttttagaaaaacagacttcagtggatgctgacgggaactttgatcccaaacct atcaacacagtgaattttacacttcctgaaaagttggagtatattgtcaacaagtacgct gaacatacacatgacaaatgggcctgtgacaagaataatagtgggtggaagtatgcatct tcactcgatgaaaatgtgaagacacatcctttaatgaggccttttaaaacactgactgaa aaggaaaaggaaatctatcgatggcctgccagagaatctcttaaaaccatgttagcaatg ggatggagcctagaaaggataaaagaaggcaattcaatggtacaacaacgtgaaagcgaa aagctccgtagcatatcacagtccagccaaggaaatggatacaacccagcaccacttgat ctttcaaatgttgtactctccagagaaatccagggaatggttgaagtggtagcagaaaac tatcataacatttgggctaaaaagaagaaaactgaattggaaagtaaaggtggaggtagt catcctttattagtaccttatgacactttgacagccaaagaaaagtctcgggatagggag aaagcacaagaactgtttaaatttcttctagtgaatggcattgtcatatccagaggctta agtggcatggagatggatgcttcatccatggaaaagaggtttgcctataaatttctgaag aagattctcaaatacgttgactctgctcaagaattcattgcacatttagaagctattgtc accagtggaaaaactgagaaatcaccacatgaccaagaaattaagttctttgccaaagtt ctgcttccactagttgaccagtattttaccaaccattgcctgtatttcctctcctcccca actaagccactcagcagtagtggatatgcttcaaataaagaaaaagaaatggtagcaagc cttttctgcaaacttgctgctcttgttagacataggatttcactttttggtagtgatgct gctacaatggttagctgcctacacatcttagctcagacactagacacaagaaccgtcatg aaatcagggtcagagctggttaaagcaggactgcgtgccttctttgaaaatgcagctgaa gatctggagaagacatcagaaaatcttaaacttggaaaatttacccattcccgtacacaa attaaaggggtctcacagaatatcaactatacaacagtggcattgttgcctgttctaaca tcaatttttgaacatgttgctcagcatcattttggcaccgatttgctattaggtgatgtc caagtatcatgctacagaattctttgtagcctgtactctcttggaactggaaagaacatt tatgttgaaagacaacgtccggctcttggtgagtgcttagcgtctcttgcagctgccatt ccagtagcctttcttgaaccttctctcaatctttacaatcccctgtctgtcttcaacaca aaaactgcaagagagagagctattttaggtatgcctgaaaccgtagaagaaatgtgtcca gaaatccctcacttggatggcttaatgaaagaaataaacagcttggcagaatctggagcc agatatactgaaatgccacacgtgattgaggtgatcttgcccatgttatgcaactatcta tcatactggtgggaaagggggcctgaaaatgctgaaagtactggcccctgctgcacaatg gtaacttctgagcatctcagcataatactggggaacattttgaagatcatcaacaataac ctggggatagatgaggcaacttggatgaagcgaatagcagtgtatgctcagccaatcatt agcaaggccaggccggatctgttgaaaagtcattttatcccaacactggagaaactaaag aagaaagccataaagatagtgatggaggaggaacaactgaaagcagacagtaaaacggat acccaagaagcagaactcctcattctagatgaatttgcagttctttgccgcgacctttat gctttttatcctatgttgatccgctatgtggacaacaacagatcaaactggcttaagaaa ccagatgcagattctgatgaacttttccgaatggtagctgaagtcttcattctctggtgt aaatcacataatttcaagcgagaagaacaaaattttgttattcagaatgaaatcaacaac ttggcatttttgacaggagacagcaagagtaagatgtcaaaatctggaggtcatgatcaa gaacgaaagaaatcaaaacgtagaggggatttatattcaatacagacttctctaattgta gctgcacttaaaaaaatgcttcccattggactgaatatgtgtacgcctggagatcaagaa ctgatatctcttgctaagttcagatacagctgtaaagacacagaagaagaggtgaaggag catttacgcaataatttgcatttgcaggagaagtcagatgacccagctgtgaaatggcag ttgaatttgtacaaggatgtcttgaaagctgatgaacctgttgatcctgagaaaatagtg cagcgtgtgcaaaggatctcagcagctgtgtatcatctggagcaggttgagcaaccatta agatcaaagaaagcagtttggcacaaactcttgtcaaaacaacgtaaaagagctgttgtg gcttgtttcaggatggcaccgttgtataatctgccaaggcaccgctctattaacctgttc ctccatggttatcagaaatattggatagaaacagaggaatattcctttgaggagaaacta gttcaggatttggctactcccccgcaaaaaagtgaggaggaggaggaagaaactgaaaag catcctgatcctcttcatcagatcattcttcatttcagccggaatgctctaaccgaacga agcaaattggaaaatgaccctttgtacactgcatattcagcaatgatggcaatgagctgt cagagtggagaaagtgatgatgatgaagaagaaaaagagaagacatttgaggaaaaagaa atggaaaagcaaaaaactctttatcagcaatctcggctccatgaacgaggagcagcagag atggtattacagatgattagtgccagtaaaggtgaaatgggacacatggtagttgaaact ttgaaacttggtattgctgttctaaatggaggaaactcagttgttcaacagaaaatgttg gactatttgaaggagaaaaaagatgctggattttttcagagtctttctggcttaatgcaa tcttgcagtgttcttgacttgaatgcctttgagagacaaaataaagcagaaggccttgga atggttactgaagaaggaacactcatcgtacgtgagcgtggtgagaaagtactacagaat gatgagtttactaaagatctgtttagatttttacaactgctgtgtgaaggtcataacaat gattttcagaactacctgcgcactcagatgggcaataccaccacagttaatattattatt agcacagttgattatcttttgcgtcttcaggaatcaatcagtgacttctactggtactac tctggaaaagatgtcattgatgaatctggacaacgtaatttctctaaggcattggctgtg actaaacagatttttaattcacttactgaatatatccaaggtccttgcattggaaaccag cagagcttggctcacagtagactgtgggatgcggttgttggcttccttcatgtttttgct aacatgcaaatgaaactttcacaggattcgagtcagattgagttgctgaaggagctacta gatcttctgaaggatatggtggtgatgctcttgtcactacttgaaggtaatgttgtaaat ggcactatcgggaaacagatggtggacactctggttgaatcatctagcaatgtagaaatg atattgaagttctttgacatgtttctcaagttgaaggatctaacaagctcagaagctttc aaagagtatgacccagaaagtaaaggcataatttccaagaaggaattccagaaagccatg gaaggtcaaaagcaatatacccaatcggagattgagttcctgctgtcctgtgcagaaaca gatgaaaacgacatgtttaactatgctgattttgttgaaagatttcacgagccagccaaa gatattggatttaatgtggccgtcctcttaacaaacctatcagaacacatgccaaatgat tcgcggcttcagactctattagatccagcagaatgtgtccttaactattttgaaccttac cttgggcgcattgagataatgggtggtgccaagaagatagagcgggtttattttgagatc agtgaatccagtaggacgcagtgggaaaagcctcaagtgaaagaatcaaaaaggcagttt atttttgatgttgtaaatgaaggtggggaacaagagaagatggagctttttgtaaacttt tgcgaggacacgatttttgaaatgcagttggcatctcagatatctgaatcggatatagtt gacagacctgaggaggaggaagatgagccttgctatgtgagggaaattggagaagatgag aaaggagagcagtcccttgaatcagcttcagcttttgctatggcatgcgttgcaataaag aaaaatgctgccactgtttttaaaatgataagactgaaaaacttaagaaaacagtacaga aaagtgagaaagatgactgtaaaagaattggttaaagtatccttttcctttctctggatg ctatttgtaggattcttccaaatgtttctgactatactgtgcagtatttttcagattctt tggagtactgtgtttgggggtggcctaatagaaggagccaaaaacattagagttactaaa attttaggagacatgcctgacccaacacagtttggaattcacgatgatgtccttgaagca gaaaaagttgaagttacagaacatggcattacagctgaaattgtgcagtttgttaaaaat gagaagggagaaactgacatcttgtcagatatttttggcattcatacgaagaaagagagc ggatcaaagcatggtcatgctgttggcctaggggatatcgctgatatcattggatcagat acccctccttctttggaaagtgcagttcgcaagaagaaaaaagcacagacacctgaaatt gcaaaggatgatgaatcggaaacaagaacagaatctgagaaggctgacatggaggatggt gagaaacaagataaaatcaaggatgatatgtattctgaacatatggaactagaagaacct agaaaacggaaacgaaagcgtgggcaaaaaattgagaaacctgatgcagttatggccaac ttttttaaagtattggaagtttatcagacaaaaatgctgcactttttggcccgaaatttc tacaatttaagatttcttgcactttttgttgcattcgccatcaactttatcctgcttttc tacaaggtaacagaagagccatttgaagaaatggaagaagattcagatctgtggcattct ttagaggaggaggaagatgaagatggagtagtcttctttgttttacaagagagtacaggc tacatggcaccaacacttagggccctagctgttatccatacaatcatctcttttgtatgt gttattggatactattgtttaaaggttcctctggttgtattcaaacgggagaaggacatt gcaaggaagctggaatttgatggtctgtatattaccgaacaaccctccgaagatgacatt aaaggacagtgggatcgcctcgtcataaatacgccatattttcctaacaattattgggac aagtttgtaaaacgaaaggtaatcaacaagtatggtgatttatatggagcagaacgcatt gcagaactcctgggtctggacaaaaatgctctggatttcagcccagtggaacatactgaa ctagaggaggcatcccttgttttgtggttaagttctattgatgccaaataccatatctgg aagcttggtgttgttttcactgataattctttcttgtacttagcttggtacacaaccatg tcaattcttggtcattacaacaacttcttctttgctgcccacttgcttgatattgctatg ggttttaagactctgcgtaccatcctgtcttctgtaacccacaatggcaaacagcttgtt ttgactgttggactcttggctgtagtggtatacctttacacggttgtggcattcaacttc ttccgcaaattttataacaagagcgaagatgaagatgagccagacatgaagtgtgatgac atgatgacgtgttacctcttccacatgtatgtgggtgtaagagcaggtggaggcattgga gatgaaattgaagaccctgcaggagacccttatgagatgtatcgaattgtttttgatatc acgtttttcttctttgtcattgtcatcctactggccatcattcaaggtctgattattgat gcctttggtgaattaagagaccagcaagagcaggtgaaagaagatatggagaccaaatgt tttatttgtggaattggtaatgactattttgacacaaccccccatggatttgaaatgcat actttacaagagcacaacttggccaactacctgttcttcctgatgtatctcattaataag gatgaaactgagcacactggacaggagtcctatgtatggaaaatgtaccaagaaagatgc tgggattttttcccagctggagactgcttccgtaaacagtatgaagatcaacttggataa

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